دانلود مقالات ISI درباره Bcrp + ترجمه فارسی

ATP-binding cassette transporters P-glycoprotein and breast cancer related protein are reduced in capillary cerebral amyloid angiopathy

Keywords: Cerebral amyloid angiopathy; Alzheimer's disease; P-gp; BCRP; ABC transporters; Blood-brain barrier;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

DJ-1 mediates the resistance of cancer cells to dihydroartemisinin through reactive oxygen species removal

Keywords: ARTs; artemisinin and its derivatives; BCRP; breast cancer resistance protein; DCF-DA; 2′,7′-dichlorodihydrofluorescein diacetate; DHA; dihydroartemisinin; DHE; dihydroethidine; 5-FU; 5-fluorouracil; GCLC; glutamate-cysteine ligase catalytic subunit

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Multidrug resistance (MDR) reversers: High activity and efficacy in a series of asymmetrical N,N-bis(alkanol)amine aryl esters

Keywords: MDR reversers; P-gp inhibitors; N,N-bis(alkanol)amine aryl esters; Chemosensitizers; Doxorubicin-resistant erythroleukemia K562 cells (K562/DOX); Pirarubicin uptake; P-gp; P-glycoprotein; BCRP; breast cancer resistance protein; MRP1; multidrug resistance-

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2014 سفارش ترجمه

Single pre-treatment with hypericin, a St. John's wort secondary metabolite, attenuates cisplatin- and mitoxantrone-induced cell death in A2780, A2780cis and HL-60 cells

Keywords: ABC; ATP-binding cassette; ABCC1; ATP-binding cassette, Sub-family C, Member 1; ABCC2; ATP-binding cassette, Sub-family C, Member 2; ABCG2; ATP-binding cassette, Sub-family G, Member 2; BCRP; breast cancer resistance protein; CDDP; cisplatin (cis-diammine

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2014 سفارش ترجمه

[11C-carbonyl]CEP-32496: Radiosynthesis, biodistribution and PET study of brain uptake in P-gp/BCRP knockout mice

Keywords: [11C]CEP-32496; PET; BRAF; P-gp; BCRP; [11C]phosgene;

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2014 سفارش ترجمه

Phenethyl isothiocyanate: A comprehensive review of anti-cancer mechanisms

Keywords: BaP; Benzo(a)pyrene; BCRP; Breast Cancer Resistance Protein; CSC; Cancer Stem cells; ECS; Environmental Cigarette Smoke; GPX; Glutathione peroxidase; GSH; Glutathione; GST; Glutathione S-transferase; HBEC; Human Bronchial Epithelial Cells; HBP; 4-hydroxy-

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2014 سفارش ترجمه

The ABC gene family in arthropods: Comparative genomics and role in insecticide transport and resistance

Keywords: Traffic ATPases; Primary carriers; Allelochemicals; Multidrug resistance; Detoxification; Phase III; Arthropoda; P-gp; MDR; MRP; BCRP; SUR; Bt toxins;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2014 سفارش ترجمه

Fatty acid-bearing albumin but not fatty acid-depleted albumin induces HIF-1 activation in human renal proximal tubular epithelial cell line HK-2

Keywords: AP-1; activator protein-1; BCRP; breast cancer resistance protein; FA(+)HSA; fatty acid-bearing human serum albumin; FA(−)HSA; fatty acid-depleted human serum albumin; FBS; fetal bovine serum; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; GLUT1; gluc

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2014 سفارش ترجمه

In vivo methods for drug absorption - Comparative physiologies, model selection, correlations with in vitro methods (IVIVC), and applications for formulation/API/excipient characterization including food effects

Keywords: ABC; ATP-Binding Cassette; An; absorption number; API; active pharmaceutical ingredient; AUC; area under the curve; BCRP; breast cancer resistant protein; BCS; biopharmaceutic classification system; BDDCS; biopharmaceutics drug disposition drug classifica

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2014 سفارش ترجمه

Activity-lipophilicity relationship studies on P-gp ligands designed as simplified tariquidar bulky fragments

Keywords: Tariquidar; P-Glycoprotein; 2-Alkyloxyquinoline; Lipophilicity; BCRP; MRP1;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

Potential role of ATP-binding cassette transporters in the intestinal transport of rhein

Keywords: ABC; ATP-binding cassettet; P-gp; P-glycoprotein; BCRP; breast cancer resistance protein; MRP2; multidrug resistance-associated protein 2; B; basolateral; A; apical; MDCKII; Mardin-Darby canine kidney II; Rhein; ATP-binding cassette transporters; Rat in

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Serotonin transporter protein (SERT) and P-glycoprotein (P-gp) binding activity of montanine and coccinine from three species of Haemanthus L. (Amaryllidaceae)

Keywords: AChE; acetylcholinesterase; BBB; blood-brain-barrier; BCRP; breast cancer resistance protein; CNS; central nervous system; P-gp; P-glycoprotein; SERT; serotonin transporter protein; SSRI; selective serotonin reuptake inhibitor; Haemanthus; Amaryllidacea

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

P-glycoprotein (Mdr1a/1b) and breast cancer resistance protein (Bcrp) decrease the uptake of hydrophobic alkyl triphenylphosphonium cations by the brain

Keywords: ABC proteins; ATP binding cassette proteins; BBB; blood-brain barrier; Bcrp; breast cancer resistance protein; CsA; cyclosporin A; IP; intra peritoneal; IV; intra venous; Mdr1; multi drug resistance 1; MitoF; 11-fluoroundecyltriphenylphosphonium mesylat

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Polycyclic aromatic hydrocarbons in food - Efflux of the conjugated biomarker 1-hydroxypyrene is mediated by Breast Cancer Resistance Protein (ABCG2) in human intestinal Caco-2 cells

Keywords: 1-OHP; 1-hydroxypyrene; ABC; ATP-binding cassette; AhR; aryl hydrocarbon receptor; BCRP; breast cancer resistance protein; B[k]F; benzo[k]fluoranthene; BP; benzo[a]pyrene; CYP; cytochrome P450 monooxygenase; INF; indeno[1,2,3-cd]fluoranthene; MRP2; multid

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

P-glycoprotein (MDR1/ABCB1) and breast cancer resistance protein (BCRP/ABCG2) restrict brain accumulation of the JAK1/2 inhibitor, CYT387

Keywords: AUC; area under the plasma concentration-time curve; Cmax; maximum drug concentration in plasma; Tmax; the time after administration of a drug when the maximum plasma concentration is reached; BBB; blood-brain barrier; BCRP; breast cancer resistance p

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

MiR-487a resensitizes mitoxantrone (MX)-resistant breast cancer cells (MCF-7/MX) to MX by targeting breast cancer resistance protein (BCRP/ABCG2)

Keywords: MiR-487a; BCRP; Multidrug resistance; Breast cancer;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Mitochondrial genome depletion in human liver cells abolishes bile acid-induced apoptosis: Role of the Akt/mTOR survival pathway and Bcl-2 family proteins

Keywords: ABC; ATP-binding cassette; Akt; protein kinase B; BCRP; Breast cancer resistance protein; BSEP; Bile salt export pump; DCA; Deoxycholic acid; DCFH-DA; 2′,7′-dichlorofluorescein diacetate; ERK; Extracellular regulated kinase; EtBr; Ethidium bromide; GC

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Research ReportPregnane X receptor upregulates ABC-transporter Abcg2 and Abcb1 at the blood-brain barrier

Keywords: ABC-transporter; ATP-binding cassette transporter; BBB; blood-brain barrier; BCRP; breast cancer related protein; BMDP; brain multidrug resistance protein; CNS; central nervous system; Fumitremorgin; C; hPXR; human PXR; Mrp2; multidrug resistance-associ

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Reversal of multidrug resistance by the inhibition of ATP-binding cassette pumps employing “Generally Recognized As Safe” (GRAS) nanopharmaceuticals: A review

Keywords: ABC; ATP-binding cassette superfamily; ART; Antiretroviral therapy; AUC; Area-Under-the-Curve; BCS; Biopharmaceutic Classification System; BCRP; Breast cancer resistance protein; CD; Cyclodextrins; CFR; Code of Federal Regulations; CMC; Critical Micellar

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2013 سفارش ترجمه

Interrelationship between ATP-binding cassette transporters and oxysterols

Keywords: ABC; ATP-binding cassette; apo; apolipoprotein; BCRP; breast cancer resistance protein; CYP; cytochrome P450; EC; epoxycholesterol; ER; endoplasmic reticulum; GS-X; glutathione-conjugate; HDL; high-density lipoprotein; INSIG; insulin-inducible genes; 7-KC

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2013 سفارش ترجمه

Effect of oxygen on multidrug resistance in the first trimester human placenta

Keywords: P-glycoprotein; BCRP; First-trimester placenta; Hypoxia; Hyperoxia; Multidrug resistance

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Phosphorylated Crkl reduction levels are associated with the lowest P-glycoprotein activity levels in cells from chronic myeloid leukemia patients

Keywords: Chronic myeloid leukemia; p-Crkl; P-glycoprotein; BCRP; Imatinib

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Constitutive androstane receptor upregulates Abcb1 and Abcg2 at the blood-brain barrier after CITCO activation

Keywords: ABC-transporter; ATP-binding cassette transporter; BBB; blood-brain barrier; BCRP; breast cancer resistance protein; BMDP; brain multidrug resistance protein; CAR; constitutive androstane receptor; CYP; cytochrome P450; pgCAR; porcine CAR; CITCO; 6-(4-c

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Intestinal drug transporters: An overview

Keywords: Intestinal drug transport; Transporter–enzyme interplay; P-gp; MRP; BCRP; PEPT; OCT; OCTN; OATP; MCT; BDDCS

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2013 سفارش ترجمه

4-Substituted-2-phenylquinazolines as inhibitors of BCRP

Keywords: BCRP; Inhibitors; Multidrug resistance; Quinazolines; Hoechst 33342;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Absolute immunoquantification of the expression of ABC transporters P-glycoprotein, breast cancer resistance protein and multidrug resistance-associated protein 2 in human liver and duodenum

Keywords: BCRP, breast cancer resistance protein; MRP2, multidrug resistance-associated protein 2; Pgp, P-glycoproteinDrug transporters; Immunoquantification; BCRP; MRP2; P-glycoprotein

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Involvement of UDP-glucuronosyltranferases and sulfotransferases in the liver and intestinal first-pass metabolism of seven flavones in C57 mice and humans in vitro

Keywords: 3-HF; 3-hydroxyflavone; 4′-HF; 4′-hydroxyflavone; 5-HF; 5-hydroxyflavone; 7-HF; 7-hydroxyflavone; 3,5-diHF; 3,5-dihydroxyflavone; 3,7-diHF; 3,7-dihydroxyflavone; 3,4′-diHF; 3,4′-dihydroxyflavone; BCRP; breast cancer resistance protein; BSA; bovine

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Potential for food-drug interactions by dietary phenolic acids on human organic anion transporters 1 (SLC22A6), 3 (SLC22A8), and 4 (SLC22A11)

Keywords: ACN; anthocyanin; BCRP; breast cancer resistance protein; Cmax; maximum plasma concentration; CHO; Chinese hamster ovary; DDI; drug-drug interaction; ES; estrone sulfate; fu; fraction unbound in plasma; FDA; Food and Drug Administration; HEK; human embr

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Mechanistic insights from comparing intrinsic clearance values between human liver microsomes and hepatocytes to guide drug design

Keywords: Metabolic stability; Human liver microsomes; Human hepatocytes; Intrinsic clearance; Hepatic transporters; Drug discovery; ADME; Absorption, distribution, metabolism, and excretion; AO; Aldehyde oxidase; BCRP; Breast cancer resistance protein; CYP; Cytoch

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Coupling of UDP-glucuronosyltransferases and multidrug resistance-associated proteins is responsible for the intestinal disposition and poor bioavailability of emodin

Keywords: AIC; Akaike's information criterion; UGT; UDP-glucuronosyltransferase; UDPGA; uridine diphosphoglucuronic acid; LTC4; leukotriene C4; NTP; National Toxicology Program; SD; Sprague-Dawley; DMEM; Dulbecco's modified Eagle's medium; AP; apical; BL; basolat

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Synthesis of methylated quercetin derivatives and their reversal activities on P-gp- and BCRP-mediated multidrug resistance tumour cells

Keywords: Quercetin; Methylated quercetin derivatives; Multidrug resistance (MDR); P-gp; BCRP; MRP1;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Actions of estrogens and endocrine disrupting chemicals on human prostate stem/progenitor cells and prostate cancer risk

Keywords: E2; estradiol; EDCs; endocrine disrupting chemicals; AR; androgen receptor; ER; estrogen receptor; PIN; prostate intraepithelial neoplasia; PCBs; Polychlorinated biphenyls; PCDDs; polychlorinated dibenzo-p-dioxins; POPs; persistent organic pollutants; TCD

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Impact of terminal dimethylation on the resistance profile of α-N-heterocyclic thiosemicarbazones

Keywords: ABC; ATP-binding cassette; BCRP; breast cancer resistance protein; BSA; bovine serum albumin; CDNB; 1-chloro-2,4-dinitrobenzene; CSA; cyclosporin A; DMF; dimethylformamide; DMSO; dimethyl sulfoxide; ESI-MS; electrospray ionization mass spectrometry; GSH;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Oleic acid decreases BCRP mediated efflux of mitoxantrone in Caco-2 cell monolayers

Keywords: Oleic acid; BCRP; Mitoxantrone; Ko143; Caco-2 cell monolayers;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Influence of hepatic and intestinal efflux transporters and their genetic variants on the pharmacokinetics and pharmacodynamics of raloxifene in osteoporosis treatment

Keywords: A - B; apical-to-basolateral; ABC transporters; ATP-binding cassette transporters; ABCB1; ATP-binding cassette transporter B1 gene (Pgp); ABCC2; ATP-binding cassette transporter C2 gene (MRP2); B - A; basolateral-to-apical; BCRP; breast cancer resista

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Research ReportThe transport of nifurtimox, an anti-trypanosomal drug, in an in vitro model of the human blood-brain barrier: Evidence for involvement of breast cancer resistance protein

Keywords: BBB; blood-brain barrier; BCRP; breast cancer resistance protein; CT; combination therapy; HAT; human African trypanosomiasis; NECT; nifurtimox-eflornithine combination therapy; S1; stage 1 of human African trypanosomiasis; S2; stage 2 of human Africa

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Perspectives des thérapies ciblées dans le cancer du sein métastatique

Keywords: thérapie ciblée; cancer du sein métastatique; HER-2; anti-angiogénèse; étude clinique; targeted therapy; metatstatic breast cancer; HER-2; anti-agiogenesis; clinical trial; ADCC; cytotoxicité à médiation cellulaire anticorps-dépendante; Akt; pro

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

Ivermectin Interacts With Human ABCG2

Keywords: BCRP; macrocyclic lactones; ADME; toxicity; ABC transporter

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Posttranslational negative regulation of glycosylated and non-glycosylated BCRP expression by Derlin-1

Keywords: BCRP; Derlin-1; N-linked glycosylation; Posttranslational regulation; ER-associated degradation (ERAD)

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Targeting maladaptive glutathione responses in lung disease

Keywords: BSO; l-buthionine sulfoximine; γ-GCL; γ-glutamylcysteine ligase; GSH; glutathione; MRP; multi-drug resistant protein; ELF; epithelial lining fluid; BALF; bronchoalveolar lavage fluid; SOD; superoxide dismutase; IPF; idiopathic pulmonary fibrosis; ARDS;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Glutamine residues in Q-loops of multidrug resistance protein MRP1 contribute to ATP binding via interaction with metal cofactor

Keywords: Sf21; Spodoptera frugiperda 21; ABC; ATP binding cassette; P-gp; P-glycoprotein; BCRP; breast cancer resistance protein; MRP1; multidrug resistance protein 1; NBD; nucleotide binding domain; TMD; transmembrane domain; LTC4; leukotriene C4; 8-N3ATP; 8-azid

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Breast cancer resistance protein BCRP (ABCG2)-mediated transepithelial nitrofurantoin secretion and its regulation in human intestinal epithelial (Caco-2) layers

Keywords: Nitrofurantoin; Intestinal secretion; Induction; β-napthoflavone; Rosiglitazone; Caco-2 cells; BCRP

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Evaluation of the P-glycoprotein- and breast cancer resistance protein-mediated brain penetration of 11C-labeled topotecan using small-animal positron emission tomography

Keywords: [11C]TPT; PET; Pgp; BCRP; Elacridar

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Research ReportP-glycoprotein and breast cancer resistance protein expression and function at the blood-brain barrier and blood-cerebrospinal fluid barrier (choroid plexus) in streptozotocin-induced diabetes in rats

Keywords: Pgp; Bcrp; Diabetes mellitus; Blood-brain barrier; Choroid plexus; ABC; ATP-binding cassette; aCSF; artificial cerebrospinal fluid; BBB; blood-brain barrier; BCEC; brain capillary endothelial cells; Bcrp; breast cancer resistance protein; BSA; bovine

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Modulation of the expression of ABC transporters in murine (J774) macrophages exposed to large concentrations of the fluoroquinolone antibiotic moxifloxacin

Keywords: Moxifloxacin; Ciprofloxacin; Efflux; Mrp4; P-gp; Bcrp

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Spatial expression and functionality of drug transporters in the intact lung: Objectives for further research

Keywords: Transporter; Lung; Pulmonary; Delivery; ATP; P-glycoprotein; MRP; BCRP; OAT; OATP; OCT; OCTN; Pharmacokinetics

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

The role of P-glycoprotein and breast cancer resistance protein (BCRP) in bacterial attachment to human gastrointestinal cells

Keywords: Caco2; MDR1; E. coli; BCRP; IBD;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Synthesis and antiproliferative activity of novel 2-aryl-4-benzoyl-imidazole derivatives targeting tubulin polymerization

Keywords: ABI; 2-aryl-4-benzoyl-imidazoles; BCRP; breast cancer resistance protein; MDR; multidrug resistance; MRP; multidrug resistance-associated proteins; Pgp; P-glycoprotein; SAR; structure-activity relationships; SMART; 4-substituted methoxybenzoyl-aryl-thia

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2011 سفارش ترجمه

Identification of MET and SRC Activation in Melanoma Cell Lines Showing Primary Resistance to PLX4032

Keywords: AK; adenylate kinase; AKT; v-akt murine thymoma viral oncogene homolog; ANOVA; analysis of variance; BCRP; breast cancer resistance protein; BRAF; v-raf murine sarcoma viral oncogene homolog B1; CCND1; cyclin D1; CRAF; v-raf-1 murine leukemia viral oncoge

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2011 سفارش ترجمه

Individual variability in the disposition of and response to clopidogrel: Pharmacogenomics and beyond

Keywords: ACS; acute coronary syndrome; ADP; adenosine 5′-diphosphate; ACEI; angiotensin-converting enzyme inhibitor; ADR; adverse drug reaction; AUC; area under the curve; BMI; body mass index; BCRP; breast cancer resistance protein; CGTA; candidate gene testing

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2011 سفارش ترجمه