
Induction of oxidative DNA damage by mesalamine in the presence of copper: A potential mechanism for mesalamine anticancer activity
Keywords: BCS, bathocuproinedisulfonic acid; 5-ASA, 5-acteylsalicylic acid, mesalamine; POBN, α-(4-pyridyl-1-oxide)-N-tert-butylnitrone; PBS, phosphate buffered saline; EPR, electron paramagnetic resonance; ROS, reactive oxygen speciesMesalamine; Copper; DNA strand