
In vivo veritas, the next frontier for functionally selective GPCR ligands
Keywords: بتا آرسستین; GPCR, G protein coupled receptors; βArr1, beta-arrestin 1; βArr2, beta arrestin 2; D2R, D2 dopamine receptor; GSK3, glycogen synthase kinase 3G protein coupled receptor; Functional selectivity; Animal models; Beta-arrestin; Cell signaling