Keywords: BFA، brefeldin A; ADF, actin-depolymerizing factor; ARF-GEF, adenosine diphosphate ribosylation factor-guanine nucleotide exchange factor; BFA, Brefeldin A; BIC, biotrophic interfacial complex; EHM, extrahaustorial membrane; EIHM, extra-invasive hyphal membrane; EIX, ethyl
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Calcineurin and mTOR inhibitors have opposing effects on regulatory T cells while reducing regulatory B cell populations in kidney transplant recipients
Keywords: BFA، brefeldin A; BFA, brefeldin A; Breg cells, regulatory B cells; B10, IL10-secreting B cells; CNI, calcineurin inhibitors; eGFR, estimated glomerular filtration rate; KT, kidney transplant; LPS, lipopolysaccharide; mTOR, mammalian target of rapamycin; PBMCs, peripheral
cCMP causes caspase-dependent apoptosis in mouse lymphoma cell lines
Keywords: BFA، brefeldin A; AM, acetoxymethylester; Bcl2, B-cell lymphoma 2; BFA, brefeldin A; Bim, Bcl-2 interacting protein; cAMP, adenosine 3′,5′-cyclic monophosphate; cCMP, cytidine 3′,5′-cyclic monophosphate; cGMP, guanosine 3′,5′-cyclic monophosphate; cNMP, nucleoside 3′,5′-cy
Mechanisms regulating cell membrane localization of the chemokine receptor CXCR4 in human hepatocarcinoma cells
Keywords: BFA، brefeldin A; AMD, AMD3100; APC, allophycocyanin; BIS, bisindolylmaleimide II; BFA, brefeldin A; DMA, dimethylamiloride; EGFP, enhanced green fluorescent protein; EGFR, epidermal growth factor receptor; ER, endoplasmic reticulum; HCC, hepatocellular carcinoma cells; Mβ
Early to Late Endosome Trafficking Controls Secretion and Zymogen Activation in Rodent and Human Pancreatic Acinar Cells
Keywords: BFA، brefeldin A; Endosome; Pancreatitis; PIKfyve; TrypsinAP, adaptor protein; BFA, brefeldin A; CCK, cholecystokinin; CLP, constitutive-like pathway; DMEM, Dulbecco’s minimal essential medium; DMSO, dimethyl sulfoxide; EE, early endosome; GDP, guanosine diphosphate; GFP,
Characterization of the putative amino acid transporter genes AtCAT2, 3 & 4: The tonoplast localized AtCAT2 regulates soluble leaf amino acids
Keywords: BFA، brefeldin A; CAT, cationic amino acid transporter; TMD, transmembrane domain; RT-PCR, reverse transcription polymerase chain reaction; GUS, β-glucuronidase; GFP, green fluorescent protein; BFA, Brefeldin A; FW, fresh weight; SD, standard deviation; Arg, arginine; Gln,
Targeting V-ATPase in primary human monocytes by archazolid potently represses the classical secretion of cytokines due to accumulation at the endoplasmic reticulum
Keywords: BFA، brefeldin A; BFA, brefeldin A; CHX, cycloheximide; DECP, diethylpyrocarbonate; ER, endoplasmic reticulum; IL, interleukin; PBMC, peripheral blood mononuclear cells; V-ATPase, vacuolar-type H(+)-ATPaseVacuolar-type H(+)-ATPase; Archazolid; Cytokines; Monocytes; Interle
Modulation of in vivo IgG crystallization in the secretory pathway by heavy chain isotype class switching and N-linked glycosylation
Keywords: BFA، brefeldin A; BFA, Brefeldin A; CB, crystalline body; CDR, complementarity-determining region; CH1, heavy chain constant domain-1; CH2, heavy chain constant domain-2; CH3, heavy chain constant domain-3; CL, light chain constant domain; CHO, Chinese hamster ovary; DIC,
Should IFN-γ, IL-17 and IL-2 be considered predictive biomarkers of acute rejection in liver and kidney transplant? Results of a multicentric study
Keywords: BFA، brefeldin A; AR, acute rejection; AUC, area under the curve; BFA, brefeldin A; ELISPOT, enzyme-linked immunosorbent spot; HCV, hepatitis C virus; IFN, interferon; IL, interleukin; Io, ionomycin; MMF, mycophenolate mofetil; PBS, phosphate buffered saline; PMA, phorbol
Low cytoplasmic pH reduces ER-Golgi trafficking and induces disassembly of the Golgi apparatus
Keywords: BFA، brefeldin A; ER, endoplasmic reticulum; CGN, cis-Golgi network; ERGIC, ER-Golgi intermediate compartment; GFP, green fluorescent protein; VSV-G, vesicular stomatitis virus glycoprotein; BFA, brefeldin A; DMEM, Dulbecco׳s modified Eagle׳s medium; GlcNAcT1, N-acetylgluc
Insulin-like growth factor binding protein-4 and -5 modulate ligand-dependent estrogen receptor-α activation in breast cancer cells in an IGF-independent manner
Keywords: BFA، brefeldin A; BFA, brefeldin A; BP-4, IGFBP-4; BP-5, IGFBP-5; BSA, bovine serum albumin; DCC, dextran-coated charcoal; DMEM, Dulbecco's modified Eagle's Medium; E2, 17β-estradiol; EGFP, enhanced green fluorescent protein; ERα, estrogen receptor-alpha; ERE, estrogen res
Dual Effects of IL-1 Overactivity on the Immune System in a Mouse Model of Arthritis due to Deficiency of IL-1 Receptor Antagonist
Keywords: BFA، brefeldin A; Arthritis; Gene expression; Mouse; TranscriptomeRA, rheumatoid arthritis; IL-1, interleukin 1; IL-1rn, IL-1 receptor antagonist; Pira, paired-Ig-like receptor A; BFA, brefeldin A; WT, wild-type; KO, IL-1rn knockout; 1M, 1 month; 4M, 4 months; Hsp, heat sh
Targeting ER stress induced apoptosis and inflammation in cancer
Keywords: BFA، brefeldin A; AP1, activator protein 1; APR, acute-phase response; ATF6, activating transcription factor 6; BFA, Brefeldin A; BiP, binding immunoglobulin protein; CHOP, C/EBP homologous protein; COX, cyclooxygenase-2; CREBH, cyclic-AMP-responsive-element-binding protei
Intracellular IL-10 detection in T cells by flowcytometry: The use of protein transport inhibitors revisited
Keywords: BFA، brefeldin A; BFA, brefeldin A; CSIF, cytokine synthesis inhibitory factor; ER, endoplasmic reticulum; IFN-γ, interferon-gamma; IL, interleukin; MFI, median fluorescence intensity; monensin−/monensin+ ratio, fraction (or MFI) of cytokine positive cells measured in the
A cell-based MHC stabilization assay for the detection of peptide binding to the canine classical class I molecule, DLA-88
Keywords: BFA، brefeldin A; β2M, beta-2-microglobulin; BARC, Bispecies Antigen Recognition Cells; BFA, brefeldin A; DLA, Dog Leukocyte Antigen; LCMV, lymphocytic choriomeningitis virus; MFI, mean fluorescence intensity; NP, nucleoprotein; TAP, transporter associated with antigen pro
Reversible stress-induced lipid body formation in fast twitch rat myofibers
Keywords: BFA، brefeldin A; ADRP, adipocyte differentiation related protein; BFA, brefeldin A; cav3-YFP, caveolin 3-yellow fluorescent protein; ER/SR, endoplasmic/sarcoplasmic reticulum; FDB, flexor digitorum brevis; HRP, horse radish peroxidase; LB, lipid body; PDI, protein disulfi
Involvement of putative glutamate receptors in plant defence signaling and NO production
Keywords: BFA، brefeldin A; Glutamate receptor; Calcium signaling; Nitric oxide; Plant defence; Tobacco; ElicitorsAP-5, d-2-amino-5-phosphono pentanoic acid; AtGLR, A. thaliana glutamate receptor-like protein; BFA, brefeldin A; [Ca2+]cyt, cytosolic free calcium concentration variati
Molecular cloning and characterization of a class II ADP ribosylation factor from the shrimp Marsupenaeus japonicus
Keywords: BFA، brefeldin A; Shrimp; WSSV; ADP ribosylation factor; DefenseArf, ADP ribosylation factor; WSSV, white spot syndrome virus; BFA, Brefeldin A; CT, cycle threshold value; EGFP, enhanced green fluorescence protein
Recent insights into the building and cycling of synaptic vesicles
Keywords: BFA، brefeldin A; AP, adaptor protein; BFA, brefeldin A; HIP1, Huntingtin-interacting protein 1; QD, quantum dot; SCAMP, secretory carrier membrane protein; VAMP, vesicle-associated membrane protein; SNAP, soluble NSF attachment protein; STED, stimulated emission depletion
Characterization of two novel ADP ribosylation factors from the shrimp Marsupenaeus japonicus
Keywords: BFA، brefeldin A; Marsupenaeus japonicus; WSSV; ADP ribosylation factor; MjArf1; MjArfnArf, ADP ribosylation factor; WSSV, white spot syndrome virus; GEFs, guanine nucleotide exchange factors; BFA, Brefeldin A; CT,, cycle threshold value; EGFP, enhanced green fluorescence
Apigenin protects HT22 murine hippocampal neuronal cells against endoplasmic reticulum stress-induced apoptosis
Keywords: BFA، brefeldin A; ATF6, activating transcription factor 6; BFA, brefeldin A; CHOP, C/EBP homologous protein; eIF2α, eukaryotic initiation factor 2α; ER, endoplasmic reticulum; ERK, extracellular-regulated kinase; GRP, glucose-regulated protein; GSH, glutathione; IRE1, inos
Biogenesis of tartrate-resistant acid phosphatase isoforms 5a and 5b in stably transfected MDA-MB-231 breast cancer epithelial cells
Keywords: BFA، brefeldin A; TRAP, tartrate-resistant acid phosphatase; FPLC, fast protein liquid chromatography; BfA, Brefeldin A; Con A, Concanavalin A; pNPP, p-nitrophenylphosphate; PVDF, polyvinylidene fluoride; AMC, 7-amino-4-methylcoumarinTartrate-resistant acid phosphatase; Pu
SAXS and X-ray Crystallography Suggest an Unfolding Model for the GDP/GTP Conformational Switch of the Small GTPase Arf6
Keywords: BFA، brefeldin A; ArfGEF, Arf-specific guanine nucleotide exchange factor; BFA, brefeldin A; GEF, guanine nucleotide exchange factor; Arf6-GDPFL, full-length Arf6-GDP; HSQC, heteronuclear single quantum coherence; SAXS, small-angle X-ray scattering; SEC-MALS, size-exclusio
Mechanisms of COPI vesicle formation
Keywords: BFA، brefeldin A; ARF, ADP-ribosylation factor; ARFGAP, ADP-ribosylation factor GTPase activating protein; BARS, brefeldin-A ADP-ribosylated substrate; BFA, brefeldin A; COP, coat protein; CtBP, C-terminal binding protein; DAG, diacylglycerol; GAP, GTPase-activating protei
A possible role of lysophospholipids produced by calcium-independent phospholipase A2 in membrane-raft budding and fission
Keywords: BFA، brefeldin A; ALP, alkaline phosphatase; LTD4, leukotriene D4; BFA, brefeldin A; BEL, bromoenol lactone; FCS, fetal calf serum; GPI, glycosylphosphatidylinositol; GPN, glycyl-l-phenylalanine 2-naphthylamide; LDH, lactate dehydrogenase; MAFP, methyl arachidonyl fluoroph
Upregulation and maintenance of gap junctional communication in lens cells
Keywords: BFA، brefeldin A; lens; gap junctions; connexin; proteasome; ERKATO, arsenic trioxide; BFA, brefeldin A; Cx, connexin; DCDMLs, dissociated cell-derived monolayers; ERK, extracellular signal-regulated kinase; FGF, fibroblast growth factor; GJIC, gap junction-mediated interc
Association of a GPI-anchored protein with detergent-resistant membranes facilitates its trafficking through the early secretory pathway
Keywords: BFA، brefeldin A; BFA, Brefeldin A; DMEM, Dulbecco's Modified Eagle Medium; DRMs, detergent-resistant membranes; ER, endoplasmic reticulum; GPI, glycosylphosphatidylinositol; MDCK, Madin Darby canine kidney; MDP, membrane dipeptidase; PrP, prion protein; TGN, trans-Golgi n
Shaping tubular carriers for intracellular membrane transport
Keywords: BFA، brefeldin A; ARF, ADP-ribosylation factor; APs, adaptor proteins; APP, amyloid precursor protein; β-COP, beta subunit of coatomer protein; BAR domain, Bin-Amphiphysin-Rvs domain; BFA, brefeldin A; CERT, ceramide-transfer protein; cPLA2α, cytosolic phospholipase A2α; C
Iron loaded ferritin secretion and inhibition by CI-976 in Aedes aegypti larval cells
Keywords: BFA، brefeldin A; H, heavy; L, light; PBM, post-blood meal; FAC, ferric ammonium citrate; DES, deferoxamine mesylate salt; HBSS, Hanks' balance salt solution; BFA, Brefeldin A; EtOH, ethanol; CytoD, Cytochalasin D; HCH, heavy chain homologue; LCH, light chain homologue; LP
Stabilization of the Tertiary Structure of the Cholera Toxin A1 Subunit Inhibits Toxin Dislocation and Cellular Intoxication
Keywords: BFA، brefeldin A; BfA, brefeldin A; CT, cholera toxin; ER, endoplasmic reticulum; ERAD, ER-associated degradation; EDTA, ethylenediaminetetraacetic acid; β-ME, β-mercaptoethanol; GSH, glutathione; PBS, phosphate-buffered saline; PBST, PBS containing 1% Triton X-100; PDI, p
Aggregation of proteins having Golgi apparatus sorting determinant induces large globular structures derived from the endoplasmic reticulum in plant seed cells
Keywords: BFA، brefeldin A; BFA, brefeldin A; DsRED, Discosoma sp. red fluorescent protein; ER, endoplasmic reticulum; GFP, green fluorescent protein; mRFP, monomeric red fluorescent protein; PAC vesicle, precursor accumulating vesicle; YFP, yellow fluorescent proteinAggregation; ER
Adenosine, through the A1 receptor, inhibits vesicular MHC class I cross-presentation by resting DC
Keywords: BFA، brefeldin A; Ado, Adenosine; 2-Cl-Ado, 2-Chloro-Adenosine; AR, Adenosine receptor; BFA, Brefeldin A; CCD, Cytochalasin D; rDC, resting DC; LAMP1, Lysosomal-associated membrane protein 1; MHC-I, Major histocompatibility complex class IAdenosine; Vesicular MHC-I cross-p
Brefeldin A inhibits vesicular MHC class I processing in resting but not in CpG- and disruption-activated DC
Keywords: BFA، brefeldin A; DC, dendritic cells; VP, vesicular MHC class I processing; BFA, Brefeldin A; OVA, ovalbumin; Cat S, cathepsin S; LAMP1, lysosomal-associated membrane protein 1DC; Vesicular MHC-I processing; TLR; Cat S; LAMP1
Adiponectin and leptin are secreted through distinct trafficking pathways in adipocytes
Keywords: BFA، brefeldin A; ARF, ADP-ribosylating factor; BFA, Brefeldin A; BSA, Bovine Serum Albumin; DAB, 3,3′-Diaminobenzidine; GGA1, Golgi localizing γ-adaptin ear homology domain ARF binding protein; GST, Glutathione-S-transferase; HRP, Horse-Radish Peroxidase; PDK1, protein ki
Transient dimerization and interaction with ERGIC-53 occur in the fibroblast growth factor receptor 3 early secretory pathway
Keywords: BFA، brefeldin A; FGFR3, fibroblast growth factor receptor 3; EndoH, endoglycosidase H; PNGaseF, peptidyl N-glycosidase F; wt, wild type; TDII, thanatophoric dysplasia type II; BFA, Brefeldin A; ER, endoplasmic reticulum; ERGIC, ER-Golgi intermediate compartment; YFP-PCA,
Opposing roles of prion protein in oxidative stress- and ER stress-induced apoptotic signaling
Keywords: BFA، brefeldin A; PrP, prion protein; BFA, brefeldin A; TUN, tunicamycin; Z-VAD-FMK, Z-Val-Ala-Asp-fluoromethyl ketone; Z-DEVD-FMK, Z-Asp-Glu-Val-Asp-fluoromethyl ketone; Z-IETD-FMK, Z-Ile-Glu-Thr-Asp-fluoromethyl ketone; Z-LEHD-FMK, Z-Leu-Glu-His-Asp-fluoromethyl ketone;
Human fucosyltransferase IX: Specificity towards N-linked glycoproteins and relevance of the cytoplasmic domain in intra-Golgi localization
Keywords: BFA، brefeldin A; Fucosyltransferase IX; Lewisx; N-Glycans; Erythropoietin; Golgi localizationAF, asialofetuin; AP-1, adaptor protein 1; BFA, brefeldin A; CNS, central nervous system; dHex, deoxyhexose; EPO, erythropoietin; FUT9, fucosyltransferase IX; FUT, fucosyltransfer
Endoplasmic reticulum-associated degradation of mutant CFTR requires a guanine nucleotide-sensitive step
Keywords: BFA، brefeldin A; CF, cystic fibrosis; CFTR, cystic fibrosis transmembrane conductance regulator; ER, endoplasmic reticulum; CHX, cycloheximide; MPA, mycophenolic acid; BFA, brefeldin A; Noc, nocodazol; H-89, isoquinolinesulfonamide; HA, hemagglutinin; mAb, monoclonal anti
Methamphetamine and 3,4-methylenedioxymethamphetamine interact with central nicotinic receptors and induce their up-regulation
Keywords: BFA، brefeldin A; BFA, Brefeldin A; CHX, cycloheximide; CsA, cyclosporin A; DA, dopamine; H-89, N-[2-((p-Bromocinnamyl)amino)ethyl]-5-isoquinolinesulfonamide; HEPES, N-[2-hydroxyethil]piperazine-N′-[2-ethanesulfonic acid]; MDMA, 3,4-methylenedioxymethamphetamine; METH, met
FGFR3 intracellular mutations induce tyrosine phosphorylation in the Golgi and defective glycosylation
Keywords: BFA، brefeldin A; ACH, achondroplasia; BFA, Brefeldin A; ER, endoplasmic reticulum; FGFR, Fibroblast Growth Factor Receptor; HCH, hypochondroplasia; TDI and TDII, thanatophoric dysplasia types I and II; TK, tyrosine kinase; WT, wild typeChondrodysplasia; Receptor; Kinase;
Dicer expression and localization in post-mitotic neurons
Keywords: BFA، brefeldin A; miRNAs, microRNAs; siRNAs, small interfering RNAs; dsRNAs, double-stranded RNAs; RNAi, RNA interference; CGNs, cerebellar granule neurons; FBS, fetal bovine serum; BME, basal medium eagle; AraC, cytosine-β-d-arabinofuranoside; BFA, brefeldin A; CHX, cyclo
Food vacuole targeting and trafficking of falcipain-2, an important cysteine protease of human malaria parasite Plasmodium falciparum
Keywords: BFA، brefeldin A; BFA, brefeldin A; BODIPY-TR-ceramide, N-((4-(4,4-difluoro-5-(2-thienyl)-4-bora-3a,4a-diaza-s-indacene-3-yl)phenoxy)acetyl)sphingosine; ER, endoplasmic reticulum; FP-2, falcipain-2; FRAP, fluorescence recovery after photobleaching; FV, food vacuole; GFP, g
Flow cytometric detection of degranulation reveals phenotypic heterogeneity of degranulating CMV-specific CD8+ T lymphocytes in rhesus macaques
Keywords: BFA، brefeldin A; APC, allophycocyanin; APC-Cy7, allophycocyanin-Cy7; Alexa700, Alexa Fluor 700; BFA, brefeldin A; CTL, cytotoxic T lymphocyte; CM, central memory; ECD, energy coupled dye; Eff, effectors; ELISPOT, enzyme-linked immunospot; EM, effector memory; FITC, fluore
The Endoplasmic Reticulum Ca2+-pump SERCA2b Interacts with G Protein-coupled Receptors and Enhances their Expression at the Cell Surface
Keywords: BFA، brefeldin A; ER, endoplasmic reticulum; β2AR, β2 adrenergic receptor; δOR, δ opioid receptor; GPCR, G protein-coupled receptor; BFA, brefeldin A; DDM, n-dodecyl-β-D-maltoside; DMEM, Dulbecco's modified Eagle medium; h, human; HEK293, human embryonic kidney 293; LH, lu
Role of the leader sequence in tobacco pectin methylesterase secretion
Keywords: BFA، brefeldin A; aa; amino acid; proPME, full-length PME gene including the 5′-sequence coding for the N-terminal PME pro-sequence region; as-proPME, proPME gene in antisense orientation; BFA, brefeldin A; CW, cell wall; ER, endoplasmic reticulum; GFP, green fluorescent p
Dynamic quantification of MHC class I–peptide presentation to CD8+ T cells via intracellular cytokine staining
Keywords: BFA، brefeldin A; APC, antigen-presenting cell; BFA, Brefeldin A; DC, dendritic cell; FCS, fetal calf serum; ICS, intracellular cytokine staining; MHC, major histocompatibility complex.CD8+ T cell; Antigen presentation; Kinetics; Intracellular cytokine staining; Brefeldin
Bafilomycin A1-sensitive pathway is required for the maturation of cystic fibrosis transmembrane conductance regulator
Keywords: BFA، brefeldin A; CF, cystic fibrosis; CFTR, CF transmembrane conductance regulator; ER, endoplasmic reticulum; BafA1, bafilomycin A1; BFA, brefeldin A; BHK, baby hamster kidney; CHO, Chinese hamster ovary; GFP, green fluorescence protein; ERGIC, ER-Golgi intermediate comp
The long and winding road: Protein trafficking mechanisms in the Plasmodium falciparum infected erythrocyte
Keywords: BFA، brefeldin A; BFA, brefeldin A; COP, coat protein; EM, electron-microscopy; ER, endoplasmic reticulum; FRAP, fluorescent recovery after photobleaching; GBP, glycophorin binding protein; GFP, green fluorescent protein; GPI, glycosyl phosphatidylinositol; HCT, host cell
Evidence for serum-deprivation-induced co-release of FGF-1 and S100A13 from astrocytes
Keywords: BFA، brefeldin A; FGF, fibroblast growth factor; ER, endoplasmic reticulum; CM, conditioned medium; BFA, Brefeldin A; TTM, ammonium tetrathiomolybdate; CICR, Ca2+-induced Ca2+ release; CNS, central nervous system; MALDI-TOF, matrix-assisted laser desorption/ionisation-time
Peroxisome biogenesis: Where Arf and coatomer might be involved
Keywords: BFA، brefeldin A; Arf, ADP ribosylation factor; BFA, brefeldin A; COP, coat protein; ER, endoplasmic reticulum; GAP, GTPase activating protein; GEF, guanine nucleotide exchange factor; GDPβS, Guanosine 5′-[β-thio]diphosphate; GMP-PNP, Guanosine 5′-[β,γ-imido]triphosphate;