Keywords: تیروزین کیناز Bruton; ABC; activated-B Cell; BTK; Bruton's tyrosine kinase; CNS; Central nervous system; CLL; chronic lymphocytic leukemia; DLBCL; Diffuse Large B-cell lymphoma; DAB; diaminobenzidin; DNMT; DNA methyltransferase; GO; gene ontology; GCB; germinal center cell lik
مقالات ISI تیروزین کیناز Bruton (ترجمه نشده)
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Keywords: تیروزین کیناز Bruton; DLBCL; diffuse large B-cell lymphoma; R-CHOP; rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone; NHL; non-Hodgkin lymphoma; GEP; gene expression profiling; COO; cell-of-origin; GCB; germinal center B-cell; ABC; activated B-cell; PMBL;
Keywords: تیروزین کیناز Bruton; Antibodies; Immunoconjugates; Immunotoxins; Ab; antibody; Ag; antigen; ADCC; antibody-dependent cell mediated cytotoxicity; ALL; acute lymphoblastic leukemia; AML; acute myeloid leukemia; AKT; protein kinase B; APC; antigen-presenting cell; Apo2L/TRAIL; t
Keywords: تیروزین کیناز Bruton; AP-1; activator protein-1; BLNK; B cell linker protein; BTK; Bruton's tyrosine kinase; CCT; choline cytidylyltransferase; CDP-choline; cytidine diphosphocholine; CEPT1; choline/ethanolamine phosphotransferase 1; Cer; ceramide; CK; choline kinase; CPT1; ch
Bruton's tyrosine kinase regulates TLR7/8-induced TNF transcription via nuclear factor-κB recruitment
Keywords: تیروزین کیناز Bruton; Macrophages; Bruton's tyrosine kinase; Toll-like receptors-7/8; R848; NFκB;
Bioanalysis of ibrutinib, and its dihydrodiol- and glutathione cycle metabolites by liquid chromatography-tandem mass spectrometry
Keywords: تیروزین کیناز Bruton; BTK; Bruton's tyrosine kinase; CGS; cysteinylglycine dipeptide; CYS; cysteine (amino acid); DHI; dihydrodiol-ibrutinib; DHP-I; dihydropeptidase-I; DMSO; dimethyl sulfoxide; GLU; glutamate (amino acid); GSH; glutathione tripeptide; GST; glutathione-S-trans
The spatial molecular pattern of integrin recognition sites and their immobilization to colloidal nanobeads determine α2β1 integrin-dependent platelet activation
Keywords: تیروزین کیناز Bruton; Platelet signaling; Platelet activation; Integrin α2β1 cluster; Nanopatterning; Biofunctionalized nanobeads and nano-sized membrane protein clusters; BCECF-AM; 2â²,7â²-Bis-(2-carboxyethyl)-5-(and-6)-carboxyfluorescein-acetoxymethyl ester; BSA; bovine
ERK1/2 inhibitors: New weapons to inhibit the RAS-regulated RAF-MEK1/2-ERK1/2 pathway
Keywords: تیروزین کیناز Bruton; Akt; oncogene in the transforming retrovirus, AKT8; AP-1; activator protein 1; ARAF; v-raf murine sarcoma 3611 viral oncogene homologue; ASK1; apoptosis signal-regulating kinase 1; BCL2; B-cell lymphoma 2; BCL-XL; B-cell lymphoma extra large; BRAF; v-raf
Patterns of constitutively phosphorylated kinases in B cells are associated with disease severity in common variable immunodeficiency
Keywords: تیروزین کیناز Bruton; BCR; B-cell receptor; Btk; Bruton's tyrosine kinase; CD40L; CD40 ligand; CVID; Common variable immunodeficiency; Erk; extracellular signal-related kinase; IκBα; NFκB inhibitor α; Ig; immunoglobulin; IVIG; intravenous immunoglobulin; PCA; principle com
A pleckstrin homology-like domain is critical for F-actin binding and cofilin-phosphatase activity of Slingshot-1
Keywords: تیروزین کیناز Bruton; Slingshot; Cofilin; Pleckstrin homology (PH) domain; Actin binding; Phosphatase; Btk; Bruton's tyrosine kinase; CD; circular dichroism; CFP; cyan fluorescent protein; Itk; interleukin-2-inducible T-cell tyrosine kinase; LHK motif; Leu-His-Lys motif; OSBP;
Compound Selectivity and Target Residence Time of Kinase Inhibitors Studied with Surface Plasmon Resonance
Keywords: تیروزین کیناز Bruton; FDA; US Food and Drug Administration; EGFR; epidermal growth factor receptor; BTK; Bruton's tyrosine kinase; SPR; surface plasmon resonance; PI3K; phosphoinositide 3-kinase; SD; standard deviation; SE; standard error; PI3K; phosphoinositide 3-kinase; SPR;
Terminal 14q32.33 deletion as a novel cause of agammaglobulinemia
Keywords: تیروزین کیناز Bruton; XLA; X-linked agammaglobulinemia; BTK; Bruton's tyrosine kinase; IGHC; Immunoglobulin heavy chain gene locus; SCID; Severe combined immunodeficiency syndrome; BCR; B-cell receptor; VDJ; Variable, diversity and joining gene segments; IGHM; Immunoglobulin h
Targeting cell adhesion and homing as strategy to cure Waldenström's macroglobulinemia
Keywords: تیروزین کیناز Bruton; Waldenström's macroglobulinemia; Adhesion; Homing; Integrin; Signaling; Bruton's tyrosine kinase;
Btk inhibition treats TLR7/IFN driven murine lupus
Keywords: تیروزین کیناز Bruton; Btk; Bruton's tyrosine kinase; TLR7; Toll-like receptor 7; BCR; B cell receptor; FcR; Fc receptor; SLE; systemic lupus erythematosus; IFN; interferon; FACS; fluorescence-activated cell sorting; MMF; mycophenolate mofetil; Lupus; Bruton's tyrosine kinase;
Immunoreceptors on neutrophils
Keywords: تیروزین کیناز Bruton; ADCC; antibody-dependent cellular cytotoxicity; ANCAs; anti-neutrophil autoantibodies; Btk; Bruton's tyrosine kinase; DAG; diacyl-glycerol; DAP12; DNAX activation protein of 12Â kDa; ERK; extracellular signal-regulated kinase; fMLP; N-Formylmethionine-leu
Microenvironment interactions and B-cell receptor signaling in Chronic Lymphocytic Leukemia: Implications for disease pathogenesis and treatment
Keywords: تیروزین کیناز Bruton; APRIL; a proliferation-inducing ligand; ATM; ataxia telangiectasia mutated; BAFF; B-cell activating factor; BAFFR; BAFF receptor; BAG6; BCL2-associated athanogene 6; BCMA; B-cell maturation antigen; BCL2; B-cell lymphoma 2; BCR; B cell receptor; bFGF; bas
PAX5 is the transcriptional activator of mucolipin-2 (MCOLN2) gene
Keywords: تیروزین کیناز Bruton; ARF6; ADP ribosylation factor 6; BAC; bacterial artificial chromosome; BLAST; basic local alignment search tool; BSAP; B-cell lineage specific activator protein; BTK; Bruton's tyrosine kinase; CD; cluster of differentiation; Cq; quantitative PCR cycle; CT
Ibrutinib and Indolent B-Cell Lymphomas
Keywords: تیروزین کیناز Bruton; Bruton's tyrosine kinase; Chronic lymphocytic leukemia/small lymphocytic lymphoma; Follicular lymphoma; Mantle cell lymphoma; Non-Hodgkin lymphoma;
The pivotal position of the actin cytoskeleton in the initiation and regulation of B cell receptor activation
Keywords: تیروزین کیناز Bruton; Abp1; actin binding protein 1; BCR; B cell receptor; Btk; Bruton's tyrosine kinase; ERM; ezrin/radixin/moesin; ITAMs; immunoreceptor tyrosine-based activation motifs; mIg; membrane immunoglobulin; PI3K; phosphatidylinositol-3 kinase; PI(3,4,5)P3; phosphat
BTK inhibitor ibrutinib is cytotoxic to myeloma and potently enhances bortezomib and lenalidomide activities through NF-κB
Keywords: تیروزین کیناز Bruton; BAFF; B cell-activating factor; BTK; Bruton's tyrosine kinase; CLL; chronic lymphocytic leukaemia; FLIP; FLICE (caspase-8)-like inhibitory protein; ibrutinib; 1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-o
B cell receptor signaling in chronic lymphocytic leukemia
Keywords: تیروزین کیناز Bruton; chronic lymphocytic leukemia; B cell receptor; microenvironment; Bruton's tyrosine kinase; spleen tyrosine kinase; phosphoinositide 3-kinase δ
STIM1 tyrosine-phosphorylation is required for STIM1-Orai1 association in human platelets
Keywords: تیروزین کیناز Bruton; STIM1; Stromal interaction molecule 1; SOCE; operated Ca2+ entry mechanism; SERCA2b; sarco-endoplasmic Ca2+-ATPase isotype 2b; IP3R II; inositol trisphosphate receptor; TRPC; transient receptor potential channel; SKFs; Src family of tyrosine kinases; Btk;
Management of indolent lymphoma: Where are we now and where are we going
Keywords: تیروزین کیناز Bruton; Indolent lymphoma; Non-Hodgkin; Follicular; Marginal zone; Small lymphocytic; Rituximab; CD20; Cyclophosphamide; Doxorubicin; Bendamustine; Fludarabine; Lenalidomide; Bortezomib; PI3K; mTOR; Bruton's tyrosine kinase; Histone deacetylase inhibitors
CommentaryClinical perspectives for irreversible tyrosine kinase inhibitors in cancer
Keywords: تیروزین کیناز Bruton; AE; adverse event; BTK; Bruton's tyrosine kinase; CI; confidence interval; CLL; chronic lymphocytic leukemia; CR; complete response; DTL; dose limiting toxicity; EGFR; epidermal growth factor receptor; FGFR; fibroblast growth factor receptor; HR; hazard r
Inhibition of IgE-mediated secretion from human basophils with a highly selective Bruton's tyrosine kinase, Btk, inhibitor
Keywords: تیروزین کیناز Bruton; Basophils; Atopy; Bruton's tyrosine kinase; Signal transduction; IgE
The transcription factor Bright plays a role in marginal zone B lymphocyte development and autoantibody production
Keywords: تیروزین کیناز Bruton; Bright; B cell regulator of immunoglobulin heavy chain transcription; MZ; marginal zone; ARID; AT-rich interaction domain; Ig; immunoglobulin; Btk; Bruton's tyrosine kinase; FO; follicular; BrTg; Bright transgenic; ANA; antinuclear antibody; BCR; B cell r
TLR signaling and effector functions are intact in XLA neutrophils
Keywords: تیروزین کیناز Bruton; XLA; X-linked agammaglobulinemia; Btk; Bruton's tyrosine kinase; Ig; immunoglobulin; TLR; Toll-like receptor; LPS; lipopolysaccharide; MFI; mean fluorescence intensity; DHR; dihydrorhodamine 123; SOD; superoxide dismutase; PMA; phorbol 12-myristate 13-ace
Genetic and demographic features of X-linked agammaglobulinemia in Eastern and Central Europe: A cohort study
Keywords: تیروزین کیناز Bruton; X-linked agammaglobulinemia; Bruton's tyrosine kinase; Demographics; Eastern and Central Europe;
Expression of IL-5Rα on B-1 cell progenitors in mouse fetal liver and involvement of Bruton's tyrosine kinase in their development
Keywords: تیروزین کیناز Bruton; B-1 cells; Eosinophils; Progenitor; Interleukin-5; Bruton's tyrosine kinase
Bruton's tyrosine kinase together with PI 3-kinase are part of Toll-like receptor 2 multiprotein complex and mediate LTA induced Toll-like receptor 2 responses in macrophages
Keywords: تیروزین کیناز Bruton; Bruton's tyrosine kinase; PI 3-kinase; Toll-like receptor-2; Lipoteichoic acid;
Btk regulates multiple stages in the development and survival of B-1 cells
Keywords: تیروزین کیناز Bruton; BCR; B cell antigen receptor; Btk; Bruton's tyrosine kinase; Btklo; transgene expressing low dose (25% of endogenous) of wild type murine Btk under the control of the IgH promoter and enhancer; PtC; phosphatidylcholine; xid; x-linked immunodeficiency; B c
Bruton's tyrosine kinase is not essential for LPS-induced activation of human monocytes
Keywords: تیروزین کیناز Bruton; X-linked agammaglobulinemia; Bruton's tyrosine kinase; LPS signaling; mitogen-activated protein kinases; tumor necrosis factor α; IL-6; oxidative burst activity; monocytesBCR, B-cell receptor; Btk, Bruton's tyrosine kinase; DC, Dendritic cell; Erk, Extrac
Spi-1 and Spi-B control the expression of the Grap2 gene in B cells
Keywords: تیروزین کیناز Bruton; BCR; B cell antigen receptor; BLNK; B cell linker protein; bp; base pair; Btk; Bruton's tyrosine kinase; cbl; Casitas b-lineage lymphoma; cDNA; complementary DNA; EDTA; ehylenediamine tetra-acetic acid; EMSA; electrophoretic mobility shift assay; FITC; fl