Behavioral impairments of the aging rat
Keywords: محدودیت کالری; Survival; Motor system; Sensory system; Sarcopenia; Caloric restriction
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Dietary restriction in Drosophila is dependent on mitochondrial efficiency and constrained by pre-existing extended longevity
Keywords: محدودیت کالری; Drosophila; Dietary restriction; Caloric restriction; Long life; Delayed onset of senescence; CR; DR; Mitochondria; Malnutrition
Transcriptome analysis of age-, gender- and diet-associated changes in murine thymus
Keywords: محدودیت کالری; Thymus; Involution; Aging; Microarray; AGEMAP; Thymocytes; Caloric restriction
Long-term treatment with N-acetylcysteine, but not caloric restriction, protects mesenchymal stem cells of aged rats against tumor necrosis factor-induced death
Keywords: محدودیت کالری; N-Acetylcysteine; Caloric restriction; Mesenchymal stem cells; Cell death; Cell proliferation; Tumor necrosis factor
La restricción de metionina en la dieta disminuye el estrés oxidativo en mitocondrias de corazón
Keywords: محدودیت کالری; Mitocondrias; Restricción calórica; Radicales libres; Envejecimiento; Daño al ADN; Mitochondria; Caloric restriction; Free radicals; Ageing; DNA damage;
Autophagy: Role in surviving environmental stress
Keywords: محدودیت کالری; Autophagy; Caloric restriction; Functional ecological assemblages; Lipofuscin; Lysosomes; Lysosomal stability; Macrofaunal diversity; Mussels; Oxidative stress; Pollutants; Selection; Tolerance
Dietary caloric restriction modifies inflammatory responses in the livers of streptozotocin-induced diabetic rats
Keywords: محدودیت کالری; Inflammation; Caloric restriction; Streptozotocin-induced diabetic rats; Interleukins; TNF-α; Haptoglobin
Caloric restriction and mitochondrial function in the ageing myocardium
Keywords: محدودیت کالری; Mitochondria; Ageing; Caloric restriction; Mitochondrial DNA polymerase; Neuregulin; Nitric oxide; Bcl-xNO, nitric oxide; mtDNA, mitochondrial deoxyribonucleic acid; Nrg, neuregulin
Caloric restriction in humans: Potential pitfalls and health concerns
Keywords: محدودیت کالری; Caloric restriction; Potential pitfalls; Health
Effects of caloric restriction and gender on rat serum paraoxonase 1 activity
Keywords: محدودیت کالری; apoA-I; apolipoprotein A-I; apoJ; apolipoprotein J; CR; caloric restriction; HDL; high-density lipoprotein; LDL; low-density lipoprotein; PON1; paraoxonase 1; 18S; 18S ribosomal RNA;
A role for fruit content in energy-restricted diets in improving antioxidant status in obese women during weight loss
Keywords: محدودیت کالری; Obesity; Oxidative stress; Fruit; Caloric restriction; Malondialdehyde; Antioxidant capacity in plasma
Stress resistance and aging: Influence of genes and nutrition
Keywords: محدودیت کالری; Stress resistance; Caloric restriction; Methionine restriction; Snell dwarf; Growth hormone receptor knockout
Overlapping and distinct functions for a Caenorhabditis elegans SIR2 and DAF-16/FOXO
Keywords: محدودیت کالری; SIR2; DAF-16; Longevity; Insulin/IGF-1 signaling; Caenorhabditis elegans; UNC-13; sir-2.1; Caloric restriction
Nampt/PBEF/Visfatin: A regulator of mammalian health and longevity?
Keywords: محدودیت کالری; Caloric restriction; Dietary restriction; Aging; PBEF; Nampt; Lifespan; Sirtuin; Sir2; NAD+ salvage pathway; Nmnat; Longevity; Nicotinamide; SIRT1; Chromatin; DNA stability; CR; DR
Caloric restriction and growth hormone receptor knockout: Effects on expression of genes involved in insulin action in the heart
Keywords: محدودیت کالری; Caloric restriction; Aging; GHR-KO; Insulin; Fatty acid; Heart
Modulation of canine immunosenescence by life-long caloric restriction
Keywords: محدودیت کالری; CR, caloric restriction; CTAC, canine thyroid adenocarcinomaAging; Caloric restriction; Immune response; Immunosenescence; Canine; longitudinal study
Uncoupling protein homologs may provide a link between mitochondria, metabolism and lifespan
Keywords: محدودیت کالری; UCP; Mitochondria; Lifespan; Oxidative stress; Insulin; Caloric restriction
Proteomics analysis provides insight into caloric restriction mediated oxidation and expression of brain proteins associated with age-related impaired cellular processes: Mitochondrial dysfunction, glutamate dysregulation and impaired protein synthesis
Keywords: محدودیت کالری; Proteomics; Brain aging; Oxidative stress; Caloric restriction; Cellular dysfunction
The involvement of macroautophagy in aging and anti-aging interventions
Keywords: محدودیت کالری; Aging; Anti-aging interventions; Caloric restriction; Insulin; IGF1; MTOR; Anti-lipolytic drug; Proteolysis; Protein; Mitochondria
Caloric restriction and intermittent fasting: Two potential diets for successful brain aging
Keywords: محدودیت کالری; Caloric restriction; Intermittent fasting; Aging
Macrosialin increases during normal brain aging are attenuated by caloric restriction
Keywords: محدودیت کالری; Macrosialin; Aging; Microglia; Caloric restriction; oxLDL; Inflammation;
Mrg19 depletion increases S. cerevisiae lifespan by augmenting ROS defence
Keywords: محدودیت کالری; CR, caloric restriction; ROS, reactive oxygen species; DCFDA, dichloro fluorescein di acetateMRG19; CSR2; Caloric restriction; Reactive oxygen species; SOD; Catalase
Effects of caloric restriction on post-spawning death of ayu
Keywords: محدودیت کالری; Apoptosis; Ayu; Caloric restriction; Caspase; Longevity; 8-OHdG;
Mecanismos que aceleran el envejecimiento: relación de la resistencia a la leptina con la insulÃnica
Keywords: محدودیت کالری; Leptinemia; Secreción insulÃnica; Obesidad; Resistencia insulÃnica; Reducción calórica; Leptinemia; Insulin secretion; Obesity; Insulin resistance; Caloric restriction;
Caloric restriction attenuates Aβ-deposition in Alzheimer transgenic models
Keywords: محدودیت کالری; Caloric restriction; AD transgenics; Amyloid deposition; Astrocyte activation;
Effects of caloric restriction on insulin pathway gene expression in the skeletal muscle and liver of normal and long-lived GHR-KO mice
Keywords: محدودیت کالری; Caloric restriction; Aging; GHR-KO; Insulin;
Starvation in humans: Evolutionary background and contemporary implications
Keywords: محدودیت کالری; Caloric restriction; Starvation; Famine; Human longevity;
Mitochondrial production of reactive oxygen species and incidence of age-associated lymphoma in OF1 mice: Effect of alternate-day fasting
Keywords: محدودیت کالری; Intermittent fasting; Caloric restriction; Aging; Lymphoma; Free radical production; Antioxidant status;
Evaluation of ovarian functionality after a dietary treatment in obese women with polycystic ovary syndrome
Keywords: محدودیت کالری; PCOS; Caloric restriction; Obesity;
Fructose metabolizing enzymes from mouse liver: influence of age and caloric restriction
Keywords: محدودیت کالری; CR; caloric restriction; F-1-P; fructose-1-phosphate; F-1,6-BP; fructose-1,6-bisphosphate; DHAP; dihydroxyacetone phosphate; GAP; glyceraldehyde-3-phosphate; 1-PFK; 1-phosphofructokinase; FK; fructokinase; TK; triokinase; PFK-1; phosphofructokinase-1; Agi
αMUPA mice: a transgenic model for longevity induced by caloric restriction
Keywords: محدودیت کالری; αMUPA transgenic mice; uPA plasminogen activator; Caloric restriction; Aging; Mitochondria; Apoptosis;
Rapid and reversible induction of the longevity, anticancer and genomic effects of caloric restriction
Keywords: محدودیت کالری; Caloric restriction; Short-term; Longevity; Cancer; Microarray; Affymetrix;
Caloric restriction and melatonin substitution: Effects on murine circadian parameters
Keywords: محدودیت کالری; Neuronal basis of behavior; Biological rhythms and sleep; Melatonin; Caloric restriction; Circadian period Ï; SCN; Locomotor activity; DD; LD;
Tandem action of exercise training and food restriction completely preserves ischemic preconditioning in the aging heart
Keywords: محدودیت کالری; Aging; Ischemic preconditioning; Exercise training; Caloric restriction;
Aging and caloric restriction: Effects on Leydig cell steroidogenesis
Keywords: محدودیت کالری; Testosterone; Leydig cell; Aging; Caloric restriction; Brown Norway rat;
Longevity genes: from primitive organisms to humans
Keywords: محدودیت کالری; Aging; Longevity; Stress resistance; Caloric restriction; Insulin-signaling;
Reversal of a hallmark of brain ageing: lipofuscin accumulation
Keywords: محدودیت کالری; Advanced glycosylation end product; Anti-ageing; Antioxidant; Blood transport; Caloric restriction; Carbonyl; CNS biopsy; Degradability; Deleteriousness; Exocytosis; Free radical; Glial uptake; Hormesis; Insulin receptor gene; In vivo; Late-life mortality
DAF-2 pathway mutations and food restriction in aging Caenorhabditis elegans differentially affect metabolism
Keywords: محدودیت کالری; Aging; Longevity; Metabolism; C. elegans; Caloric restriction; Ins/IGF-1 signaling;
Peripheral lymphocyte 8-OHdG levels correlate with age-associated increase of tissue oxidative DNA damage in Sprague-Dawley rats. Protective effects of caloric restriction
Keywords: محدودیت کالری; Aging; DNA oxidation; 8-hydroxy-deoxyguanosine; Caloric restriction; Immunohistochemistry;
Caloric restriction prevents aging-associated changes in spike-mediated Ca2+ accumulation and the slow afterhyperpolarization in hippocampal CA1 pyramidal neurons
Keywords: محدودیت کالری; hippocampus; aging; calcium; diet; CA1; dendrite; aCSF; artificial cerebrospinal fluid; ANOVA; analysis of variance; CR; caloric restriction; EGTA; ethylene glycol-bis[β-aminoethyl ether]-N,N,Nâ²,Nâ²-tetraacetic acid; HEPES; n-[2-hydroxyethyl]piperazin
Effects of long-term caloric restriction on glucose homeostasis and on the first steps of the insulin signaling system in skeletal muscle of normal and Ames dwarf (Prop1df/Prop1df) mice
Keywords: محدودیت کالری; Ames dwarf mice; Aging; Caloric restriction; Insulin sensitivity; Insulin receptor; IRS-1; PI 3-kinase;
Undernutrition without malnutrition as a protective factor to prevent DNA damage in the elderly
Keywords: محدودیت کالری; Caloric restriction; DNA damage; Elderly; Comet assay;
Caloric restriction modulates insulin receptor signaling in liver and skeletal muscle of rat
Keywords: محدودیت کالری; Caloric restriction; Tyrosine phosphorylation; Insulin receptor; Protein tyrosine phosphatase-1B;
Accelerated aging pathology in ad libitum fed XpdTTD mice is accompanied by features suggestive of caloric restriction
Keywords: محدودیت کالری; Accelerated aging; Caloric restriction; Longevity study; Pathology features; XpdTTD mice;
Energy expenditure of calorically restricted rats is higher than predicted from their altered body composition
Keywords: محدودیت کالری; Caloric restriction; Aging; Metabolic rate; Doubly labeled water; Organ morphometrics;
Why dietary restriction substantially increases longevity in animal models but won't in humans
Keywords: محدودیت کالری; Aging; Caloric restriction; Primate life extension; Reproductive effort; Life history trade-offs; Evolution of senescence; Maximum longevity;
Short-term caloric restriction improves ischemic tolerance independent of opening of ATP-sensitive K+ channels in both young and aged hearts
Keywords: محدودیت کالری; Aging; Caloric restriction; Myocardial ischemia; Potassium channel; Preconditioning;
The influence of dominant lethal mutations on litter size and body weight and the consequent impact on transgenerational carcinogenesis
Keywords: محدودیت کالری; Transgenerational carcinogenesis; Dominant lethal mutations; Body weight; Caloric restriction; Radiation;
Fat intake reverses the beneficial effects of low caloric intake on skeletal muscle mitochondrial H2O2 production
Keywords: محدودیت کالری; ROS; reactive oxygen species; HC; high carbohydrate; HF; high fat; ETC; electron transport chain; PTP; permeability transition pore; EE; energy expenditure; TEE; total EE; EEdark; EE during the dark phase; BSA; bovine serum albumin; BCA; bicinchoninic aci
Genes determining yeast replicative life span in a long-lived genetic background
Keywords: محدودیت کالری; Yeast aging; Caloric restriction; Genetic pathways;