Mecanismos que aceleran el envejecimiento: relación de la resistencia a la leptina con la insulínica

caloric restriction appears to act directly on the normalization process of hyperleptinemia. Finally, it is postulated that this phenomenon would be part of a sort of repair mechanism to the hypothalamic leptin resistance of obesity, on which indirectly depends, or follows, the recovery of insulin sensitivity linked to weight and glycaemic normalization.