دانلود مقالات ISI درباره CAR، گیرنده اصلی آندروستان + ترجمه فارسی

Pregnane X receptor mediates the induction of P-glycoprotein by spironolactone in HepG2 cells

Keywords: CAR، گیرنده اصلی آندروستان; CAR, constitutive androstane receptor; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; KTZ, ketoconazole; P-gp, P-glycoprotein; PXR, pregnane X receptor; Rh123, rhodamine 123; RIF, rifampicin; SL, spironolactoneHepG2 cells; Cytotoxicity; P-glycoprotein;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Modulation of constitutive androstane receptor (CAR) and pregnane X receptor (PXR) by 6-arylpyrrolo[2,1-d][1,5]benzothiazepine derivatives, ligands of peripheral benzodiazepine receptor (PBR)

Keywords: CAR، گیرنده اصلی آندروستان; CAR, constitutive androstane receptor; CITCO, 6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime; DCPPBT, 7-(dimethylcarbamoyloxy)-6-phenylpyrrolo-[2,1-d][1,5]benzothiazepine; FGIN-1-27, N,N-dihexyl-2-(4-fluorophenyl)

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

From differential induction of UDP-glucuronosyltransferases in rat liver to characterization of responsible ligand-activated transcription factors, and their multilevel crosstalk in humans

Keywords: CAR، گیرنده اصلی آندروستان; AhR, Ah receptor; BaP, benzo[a]pyrene; CAR, constitutive androstane receptor; CYP, cytochrome P450; GR, glucocorticoid receptor; GST, glutathione S-transferase; gtPBREM, glucuronyltransferase Phenobarbital-Responsive Enhancer Module; HETE, hydroxyeicosate

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

The cap’n’collar transcription factor Nrf2 mediates both intrinsic resistance to environmental stressors and an adaptive response elicited by chemopreventive agents that determines susceptibility to electrophilic xenobiotics

Keywords: CAR، گیرنده اصلی آندروستان; AhR, arylhydrocarbon receptor; ARE, antioxidant response element; BSO, buthionine sulfoximine; bZIP, basic-region leucine zipper; CAR, constitutive androstane receptor; CNC, cap’n’collar; CYP, cytochrome P450; GCLC, glutamate–cysteine ligase catalytic; GC

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Induction of a detoxification gene in Drosophila melanogaster requires an interaction between tissue specific enhancers and a novel cis-regulatory element

Keywords: CAR، گیرنده اصلی آندروستان; Xenobiotic; Cytochrome P450; Gene regulation; Tissue specific expression; Midgut; DetoxificationCRE, cis-regulatory element; PB, Phenobarbital; P450, cytochrome 450; PXR, pregnane X receptor; CAR, constitutive androstane receptor; AhR, aryl hydrocarbon re

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Cytochrome P450 is regulated by noradrenergic and serotonergic systems

Keywords: CAR، گیرنده اصلی آندروستان; CYP, cytochrome P450; AhR, arylhydrocarbon receptor; CAR, constitutive androstane receptor; PXR, pregnane X receptor; GR, glucocorticoid receptor; HPLC, high performance liquid chromatography; DSP-4, N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine; PCA, p-ch

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Ortho-aminoazotoluene activates mouse constitutive androstane receptor (mCAR) and increases expression of mCAR target genes

Keywords: CAR، گیرنده اصلی آندروستان; OAT, Ortho-Aminoazotoluene 2′-3-dimethyl-4-aminoazobenzene; 3′-MeDAB, 3′-methyl-4-dimethylaminoazobenzene; CAR, Constitutive Androstane Receptor; CYP450s, Cytochromes P450; TCPOBOP, 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene; BrdU, bromodeoxyuridineOrtho-

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

PXR Prevents Cholesterol Gallstone Disease by Regulating Biosynthesis and Transport of Bile Salts

Keywords: CAR، گیرنده اصلی آندروستان; Fgf15; PCN; Nuclear Receptor; Gene Regulation; Transgenic MiceAbc, ATP binding cassette; Asbt, apical sodium-dependent bile acid transporter; Bsep, bile salt export pump; CAR, constitutive androstane receptor; CGD, cholesterol gallstone disease; CSI, chol

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

A comparative integrated transcript analysis and functional characterization of differential mechanisms for induction of liver hypertrophy in the rat

Keywords: CAR، گیرنده اصلی آندروستان; AhR, Aryl hydrocarbon Receptor; CAR, Constitutive Androstane Receptor; Cyp, Cytochrome P450; FA, fatty acid; LH, liver hypertrophy; Nrf2, NF-E2-related factor 2; PP, Peroxisome Proliferator; PPAR, Peroxisome Proliferator Activated Receptor; PXR, Pregnane

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Effects of dinuclear copper(II) complexes with 6-(benzylamino)purine derivatives on AhR and PXR dependent expression of cytochromes P450 CYP1A2 and CYP3A4 genes in primary cultures of human hepatocytes

Keywords: CAR، گیرنده اصلی آندروستان; Human hepatocytes; Cytochrome P450; Dinuclear copper(II) complexes; Gene inductionAhR, Aryl hydrocarbon receptor; CAR, Constitutive androstane receptor; CYP, Cytochrome P450; DRE, Dioxin-responsive element; HepG2, Human hepatoma cells; L1, 6-[(2-methoxybe

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Investigation of Orlistat effects on PXR activation and CYP3A4 expression in primary human hepatocytes and human intestinal LS174T cells

Keywords: CAR، گیرنده اصلی آندروستان; AhR, aryl hydrocarbon receptor; CAR, constitutive androstane receptor; CYP3A4, cytochrome P450 isoform 3A4; DMSO, dimethylsulphoxide; LS174T, human Caucasian colon adenocarcinoma cell line; ORL, Orlistat; PXR, pregnane X receptor; RIF, rifampicinCytochrom

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Benzodiazepines medazepam and midazolam are activators of pregnane X receptor and weak inducers of CYP3A4: Investigation in primary cultures of human hepatocytes and hepatocarcinoma cell lines

Keywords: CAR، گیرنده اصلی آندروستان; AhR, Aryl hydrocarbon receptor; ALP, Alprazolam; BRO, Bromazepam; CAR, Constitutive Androstane Receptor; CDX, Chlordiazepoxide; CLO, Clonazepam; CYP, Cytochrome P450; DIA, Diazepam; DMSO, Dimethylsulfoxide; HepG2, Human Caucasian Hepatocarcinoma Cells; LO

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Regulation of CYP3A4 by pregnane X receptor: The role of nuclear receptors competing for response element binding

Keywords: CAR، گیرنده اصلی آندروستان; CAR, constitutive androstane receptor; COUP-TF, chicken ovalbumin upstream promoter transcription factor; CYP, cytochrome P450; DMSO, dimethyl sulfoxide; DR, direct repeat; ER, everted repeat; FXR, farnesoid X receptor; IR, inverted repeat; kb, kilobase p

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Retinoids activate RXR/CAR-mediated pathway and induce CYP3A

Keywords: CAR، گیرنده اصلی آندروستان; ALHD, aldehyde dehydrogenases; CYP, cytochrome P450; RA, retinoic acid; All-trans RP, all-trans retinol palmitate; PXR, pregnane X receptor; CAR, constitutive androstane receptor; RXR, retinoid X receptor; mCAR, mouse constitutive androstane receptor; mRX

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Functions and transcriptional regulation of adult human hepatic UDP-glucuronosyl-transferases (UGTs): Mechanisms responsible for interindividual variation of UGT levels

Keywords: CAR، گیرنده اصلی آندروستان; AhR, Ah receptor; CAR, constitutive androstane receptor; PPAR, peroxisome proliferator-activated receptor; PXR, pregnane X receptor; UGT, UDP-glucuronosyltransferaseHepatic UGTs; Human liver; Interindividual variation; Transcription factors; Xenosensors

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Werner's syndrome helicase participates in transcription of phenobarbital-inducible CYP2B genes in rat and mouse liver

Keywords: CAR، گیرنده اصلی آندروستان; Ab, antibody; CAR, constitutive androstane receptor; C/EBPα, CCAAT/enhancer binding protein α; ChIP, chromatin immunoprecipitation; EMSA, electrophoresis mobility shift assay; FXR, farnesoid X receptor; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; HPR

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Involvement of pregnane X receptor in the regulation of CYP2B6 gene expression by oltipraz in human hepatocytes

Keywords: CAR، گیرنده اصلی آندروستان; ARE, antioxidant responsive element; CAR, constitutive androstane receptor; CYP, cytochrome P450; Nrf2, nuclear factor-erythroid 2-related factor 2; PBREM, Phenobarbital Responsive Enhancer Module; PXR, pregnane X receptor; RXR, retinoid acid X receptorOl

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Constitutive androstane receptor transcriptionally activates human CYP1A1 and CYP1A2 genes through a common regulatory element in the 5′-flanking region

Keywords: CAR، گیرنده اصلی آندروستان; AhR, aryl hydrocarbon receptor; XRE, xenobiotic-responsive element; CYP, cytochrome P450; CAR, constitutive androstane receptor; RXRα, retinoid X receptor α; h, human; PB, phenobarbital; DMEM, Dulbecco's modified Eagle's medium; FBS, fetal bovine serum; C

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Endocrine disruptors and thyroid hormone physiology

Keywords: CAR، گیرنده اصلی آندروستان; T3, triiodothyronine; T4, thyroxine; TH, thyroid hormone; TSH, thyrotropin; CAR, constitutive androstane receptor; PPAR, peroxisome proliferator-activated receptors; PXR, pregnane X receptor; RXR, retinoid X receptor; TR, thyroid hormone receptor; N-CoR,

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Estrogen receptor-dependent regulation of CYP2B6 in human breast cancer cells

Keywords: CAR، گیرنده اصلی آندروستان; ER, estrogen receptor; ChIP, chromatin immunoprecipitation; ChIP-chip, chromatin immunoprecipitation on microarray chip; NCoA3, nuclear coactivator 3; ERE, estrogen response element; CYP, cytochrome P450; CAR, constitutive androstane receptor; RXR, retino

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Enhanced steatosis by nuclear receptor ligands: A study in cultured human hepatocytes and hepatoma cells with a characterized nuclear receptor expression profile

Keywords: CAR، گیرنده اصلی آندروستان; AR, androgen receptor; BSA, bovine serum albumin; CAR, constitutive androstane receptor; CD36/FAT, fatty acid translocase; COUP-TF, chicken ovalbumin upstream promoter transcription factor; DMEM, Dulbecco's modified eagle medium; ER, estrogen receptor; FA

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2010 سفارش ترجمه

Rational quantitative structure–activity relationship (RQSAR) screen for PXR and CAR isoform-specific nuclear receptor ligands

Keywords: CAR، گیرنده اصلی آندروستان; BPA, bisphenol A; CAR, constitutive androstane receptor; CITCO, 6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime; DMSO, dimethylsulfoxide; LBD, ligand binding domain; NR, nuclear receptor; PK11195, 1-(2-chlorophenyl

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2010 سفارش ترجمه

Up-regulation of CAR expression through Elk-1 in HepG2 and SW480 cells by serum starvation stress

Keywords: CAR، گیرنده اصلی آندروستان; Constitutive androstane receptor; Serum starvation; Elk-1; SP600125; HepG2 cell; SW480 cellAhR, aryl hydrocarbon receptor; CAR, constitutive androstane receptor; DMEM, Dulbecco’s modified Eagle’s medium; FCS, fetal calf serum; HNF4α, hepatocyte nuclear fa

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

PXR-mediated transcriptional activation of CYP3A4 by cryptotanshinone and tanshinone IIA

Keywords: CAR، گیرنده اصلی آندروستان; PXR, pregnane X receptor; CAR, constitutive androstane receptor; GR, glucocorticoid receptor; PXRE, PXR response element; hPXR, human PXR; PCR, polymerase chain reaction; wt, wild-typeCryptotanshinone; Tanshinone IIA; PXR; CYP3A4; Induction

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Comparison of citrus coumarins on carcinogen-detoxifying enzymes in Nrf2 knockout mice

Keywords: CAR، گیرنده اصلی آندروستان; ARE, antioxidant response element; CAR, constitutive androstane receptor; CDNB, 1-chloro-2,4-dinitrobenzene; DCPIP, 2,6-dichloroindophenolate; DCNB, 1,2-dichloro-4-nitrobenzene; FAD, flavin adenine dinucleotide; GST, glutathione S-transferase; Keap 1, Kel

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Reproducible chemical-induced changes in gene expression profiles in human hepatoma HepaRG cells under various experimental conditions

Keywords: CAR، گیرنده اصلی آندروستان; CAR, constitutive androstane receptor; Cy3-CTP, cyanine 3-cytosine triphosphate; Cy5-CTP, cyanine 5-cytosine triphosphate; CYP450, cytochrome P450; DMSO, dimethyl sulfoxide; FCS, fetal calf serum; IPA, Ingenuity Pathways Analysis; PB, phenobarbital; PCA,

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Metabolic preconditioning of donor organs: Defatting fatty livers by normothermic perfusion ex vivo

Keywords: CAR، گیرنده اصلی آندروستان; Nuclear receptors; Normothermic perfusion; Hepatocytes; Steatosis; Liver transplantationOLT, Orthotopic liver transplantation; PPARs, Peroxisome proliferators-activated receptors; PXR, Pregnane X receptor (PXR); CAR, Constitutive Androstane Receptor; PBEF

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Identification of potential mechanisms of toxicity after di-(2-ethylhexyl)-phthalate (DEHP) adult exposure in the liver using a systems biology approach

Keywords: CAR، گیرنده اصلی آندروستان; Alas1, aminolevulinic acid synthase 1; Bmal1/Arntl, aryl hydrocarbon receptor nuclear translocator-like; CAR, Constitutive Androstane Receptor; Cyp, cytochrome P450; DEHP, di-(2-ethylhexyl)-phthalate; Elovl3, elongation of very long chain fatty acids 3; G

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Coordinate regulation of human drug-metabolizing enzymes, and conjugate transporters by the Ah receptor, pregnane X receptor and constitutive androstane receptor

Keywords: CAR، گیرنده اصلی آندروستان; AHR, aryl hydrocarbon receptor; ARE, antioxidant response element; BaP, benzo[a]pyrene; BCRP, breast cancer resistance protein; BSEP, bile salt export pump; CAR, constitutive androstane receptor; FXR, farsenoid X receptor; GR, glucocorticoid receptor; LXR

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Expression and transcriptional regulation of ABC transporters and cytochromes P450 in hCMEC/D3 human cerebral microvascular endothelial cells

Keywords: CAR، گیرنده اصلی آندروستان; ABC, ATP-binding cassette; AhR, aryl hydrocarbon receptor; BBB, blood–brain barrier; BCRP, breast cancer resistance protein; CAR, constitutive androstane receptor; CNS, central nervous system; CYP, cytochromes P450; MDR, multidrug resistance; MRP, multidr

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2009 سفارش ترجمه

Recent insights into hepatic lipid metabolism in non-alcoholic fatty liver disease (NAFLD)

Keywords: CAR، گیرنده اصلی آندروستان; ACC, acetyl-CoA carboxylase; 2-AG, 2-arachidonoylglycerol; AMPK, AMP-activated protein kinase; ASO, antisense oligonucleotides; BMI, body mass index; CAR, constitutive androstane receptor; ChREBP, carbohydrate responsive element binding protein; CPT1A, ca

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2009 سفارش ترجمه

Expression of CAR in SW480 and HepG2 cells during G1 is associated with cell proliferation

Keywords: CAR، گیرنده اصلی آندروستان; CAR, constitutive androstane receptor; CDK, cyclin-dependent kinase; PXR, pregnane X receptor; RXR, retinoid X receptor; UGT, UDP-glucuronosyltransferaseCAR; CDK4; MDM2; Cell proliferation; HGF; UGT1A1

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

The CYP2B2 5′ flank contains a complex glucocorticoid response unit

Keywords: CAR، گیرنده اصلی آندروستان; CAR, constitutive androstane receptor; DEX, dexamethasone; DMSO, dimethyl sulfoxide; EMSA, electrophoretic mobility shift assays; FBS, fetal bovine serum; GR, glucocorticoid receptor; GRE, glucocorticoid response element; GRU, glucocorticoid response unit

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Application and interpretation of hPXR screening data: Validation of reporter signal requirements for prediction of clinically relevant CYP3A4 inducers

Keywords: CAR، گیرنده اصلی آندروستان; CAR, constitutive androstane receptor; CYP, cytochrome P450; DEX, dexamethasone; GR, glucocorticoid receptor; NCEs, new chemical entities; PB, phenobarbital; PCN, pregnenolone 16α-carbonitrile; PPAR, peroxisome proliferator activated receptor; PXR, pregna

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Discovery of substituted sulfonamides and thiazolidin-4-one derivatives as agonists of human constitutive androstane receptor

Keywords: CAR، گیرنده اصلی آندروستان; CAR, constitutive androstane receptor; CITCO, 6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)-oxime; CYP, cytochrome P450; EE2, 17α-ethynyl-3,17β-estradiol; H12, helix 12; LBD, ligand-binding domain; LBP, ligand-binding

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Coordinated induction of drug transporters and phase I and II metabolism in human liver slices

Keywords: CAR، گیرنده اصلی آندروستان; PB, phenobarbital; BNF, β-naphthoflavone; RIF, rifampicin; CAR, constitutive androstane receptor; AhR, aryl hydrocarbon receptor; PXR, steroid and xenobiotics receptor; 7-EC, 7-ethoxycoumarin; BSEP (ABCB11), canalicular bile salt export pump; 7-HC, 7-hydr

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Microtubules-interfering agents restrict aryl hydrocarbon receptor-mediated CYP1A2 induction in primary cultures of human hepatocytes via c-jun-N-terminal kinase and glucocorticoid receptor

Keywords: CAR، گیرنده اصلی آندروستان; AhR, aryl hydrocarbon receptor; ARNT, aryl hydrocarbon receptor nuclear translocator; CAR, constitutive androstane receptor; CHX, cycloheximide; CYP, cytochrome P450; ERK, extracellular-regulated protein kinase; dimethylsulfoxide; GAPDH, glyceraldehyde-3-

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Changes in maternal liver Cyp2c and Cyp2d expression and activity during rat pregnancy

Keywords: CAR، گیرنده اصلی آندروستان; RT-PCR, real time PCR; RAR, retinoic acid receptor; RXR, retinoid X receptor; HNF, hepatic nuclear factor; PXR, pregnane X receptor; CAR, constitutive androstane receptor; PBS, phosphate buffered saline; TE, tris-EDTA(8) Pharmacokinetics; Drug metabolismL

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Expression profile of liver genes in response to hepatotoxicants identified using a SAGE-based customized DNA microarray system

Keywords: CAR، گیرنده اصلی آندروستان; BPA, bisphenol A; CAR, constitutive androstane receptor; Cd, cadmium chloride; CT, carbon tetrachloride; CYP, cytochrome P-450; DEHP, di-(2-ethylhexyl) phthalate; E2, 17β-estradiol; EDC, endocrine-disrupting chemical; ER, estrogen receptor; IPA, ingenuity

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Effects of naturally occurring coumarins on hepatic drug-metabolizing enzymes inmice

Keywords: CAR، گیرنده اصلی آندروستان; B[a]P, Benzo[a]pyrene; CAR, constitutive androstane receptor; CDNB, 1-chloro-2,4-dinitrobenzene; DCNB, 1,2-dichloro-4-nitrobenzene; DCPIP, 2,6-dichloroindophenolate hydrate; DMBA, 7,12-dimethylbenz[a]anthracene; DME, drug-metabolizing enzymes; EA, ethacry

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2008 سفارش ترجمه

Phenobarbital suppresses vitamin D3 25-hydroxylase expression: A potential new mechanism for drug-induced osteomalacia

Keywords: CAR، گیرنده اصلی آندروستان; CYP, cytochrome P450; CYP27A1, mitochondrial sterol 27-hydroxylase/vitamin D3 25-hydroxylase; CAR, constitutive androstane receptor; PXR, pregnane X receptor; RXR, retinoid X receptor; RLU, relative light unitsBioactivation of vitamin D3; 25-Hydroxylation

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Xenobiotic- and vitamin D-responsive induction of the steroid/bile acid-sulfotransferase Sult2A1 in young and old mice: The role of a gene enhancer in the liver chromatin

Keywords: CAR، گیرنده اصلی آندروستان; PCN, pregnenolone-16α-carbonitrile; D3, 1α,25-dihydroxy vitamin D3; IR0, inverted repeat-zero spacer; VDR, vitamin D receptor; PXR, pregnane X receptor; RXR-α, retinoid X receptor α; CAR, constitutive androstane receptor; ChIP, chromatin immunoprecipitati

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Expression, protein stability and transcriptional activity of retinoic acid receptors are affected by microtubules interfering agents and all-trans-retinoic acid in primary rat hepatocytes

Keywords: CAR، گیرنده اصلی آندروستان; AhR, aryl hydrocarbon receptor; ATRA, all-trans-retinoic acid; CAR, constitutive androstane receptor; COL, colchicine; DEX, dexamethasone; GR, glucocorticoid receptor; HeLa, human cervix carcinoma epithelial cell line; JNK, c-Jun-N-terminal kinase; MG-132

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

The human hepatoma HepaRG cells: A highly differentiated model for studies of liver metabolism and toxicity of xenobiotics

Keywords: CAR، گیرنده اصلی آندروستان; AhR, aryl hydrocarbon receptor; BSEP, bile salt export pump; CAR, constitutive androstane receptor; CYP, cytochrome P450; DMSO, dimethylsulfoxide; GST, glutathione transferase; MRP, multidrug-resistance associated protein; NTCP, Na+-taurocholate co-transp

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Regulatory mechanisms to control tissue α-tocopherol

Keywords: CAR، گیرنده اصلی آندروستان; α-CEHC, 2,5,7,8-tetramethyl-2-(2′-carboxyethyl)-6-hydroxychroman; CYP, cytochrome P450; MDR, multidrug resistance; SQ, subcutaneous; ABC transport protein, ATP-binding cassette transport protein; DEX, dexamethasone; CAR, constitutive androstane receptor;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Downregulation of the reduced folate carrier transport activity by phenobarbital-type cytochrome P450 inducers and protein kinase C activators

Keywords: CAR، گیرنده اصلی آندروستان; ALL, acute lymphoblastic leukemia; BHQ, black hole quencher; BIM, bisindolylmaleimide, bZIP, leucine-rich dimerization domain; DB-cAMP, dibutyryl-3′,5′cyclo-adenosinmonophosphate; cDNA, complementary DNA; CAR, constitutive androstane receptor; DMEM, Dulbe

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Nuclear receptors in human immune cells: Expression and correlations

Keywords: CAR، گیرنده اصلی آندروستان; ARM, adjacent rank mismatch; CAR, constitutive androstane receptor; CoupTF, chicken ovalbumin upstream promoter-transcription factor; ER, estrogen receptor; FXR, farnesoid X receptor; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; GCNF, germ cell nuclea

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Corepressors of agonist-bound nuclear receptors

Keywords: CAR، گیرنده اصلی آندروستان; aa, amino acid; AF-2, activation function 2; at-RA, all trans-retinoic acid; CAR, constitutive androstane receptor; CBP, CREB-binding protein; CtBP, C-terminal-binding protein; ER, estrogen receptor; EZH2, enhancer of zeste homolog 2; GR, glucocorticoid r

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Proximal HNF1 element is essential for the induction of human UDP-glucuronosyltransferase 1A1 by glucocorticoid receptor

Keywords: CAR، گیرنده اصلی آندروستان; UGT, UDP-glucuronosyltransferase; PB, phenobarbital; PBREM, PB response enhancer module; DE, distal element; DEX, dexamethasone; GR, human glucocorticoid receptor; GRE, glucocorticoid responsive element; CAR, constitutive androstane receptor; PXR, human p

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Inducibility of UDP-glucuronosyltransferase 1As by β-naphthoflavone in HepG2 cells

Keywords: CAR، گیرنده اصلی آندروستان; UDP-glucuronosyltransferase (UGT); UGT1A; HepG2 cells; β-naphthoflavone (BNF); InducibilityAhR, aryl hydrocarbon receptor; BNF, β-naphthoflavone; CAR, constitutive androstane receptor; CYP, cytochrome P450; DMSO, dimethyl sulfoxide; GAPDH, glyceraldehyde

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه