دانلود مقالات ISI درباره سرطان زایی + ترجمه فارسی

Mechanistic insights into the bioactivation of phenacetin to reactive metabolites: A DFT study

Keywords: سرطان زایی; Phenacetin; Carcinogenicity; Density functional theory; Reactive metabolites; Electrophilicity; Quinone imine;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Evaluation of propargyl alcohol toxicity and carcinogenicity in F344/N rats and B6C3F1/N mice following whole-body inhalation exposure

Keywords: سرطان زایی; Propargyl alcohol; Toxicity; Carcinogenicity; Chronic; Occupational; Respiratory;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

The OSIRIS Weight of Evidence approach: ITS mutagenicity and ITS carcinogenicity

Keywords: سرطان زایی; Bayes' theorem; Carcinogenicity; Decision theory; In vitro; In vivo; Mutagenicity; QSARs; Read-across; Swing weighting; Testing strategies;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Toxicogenomic approaches for understanding molecular mechanisms of heavy metal mutagenicity and carcinogenicity

Keywords: سرطان زایی; Carcinogenicity; Heavy metal; Mutagenicity; Toxicogenomics; Environment

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Exposición a fármacos citotóxicos en el personal sanitario

Keywords: سرطان زایی; Agente citotóxico; Nivel umbral; Exposición ocupacional; Carcinogenicidad; Cytotoxic agent; Threshold level; Exposure in the workplace; Carcinogenicity;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Naphthalene animal carcinogenicity and human relevancy: Overview of industries with naphthalene-containing streams

Keywords: سرطان زایی; Naphthalene; Epidemiology; Human; Carcinogenicity; Nasal cancer; Lung cancer; Respiratory;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Human safety risk assessment of lymph node angiomas observed in 2-year carcinogenicity studies in rats

Keywords: سرطان زایی; Angioma; Carcinogenicity; Lymph node; Lymphangioma; Rat; Human safety risk assessment;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Mini-reviewRecent progress in studies of metallic nickel and nickel-based nanoparticles' genotoxicity and carcinogenicity

Keywords: سرطان زایی; Genotoxicity; Carcinogenicity; Nickel; Nanoparticles;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Preliminary evaluation of the human relevance of respiratory tumors observed in rodents exposed to naphthalene

Keywords: سرطان زایی; Naphthalene; Mode of action; Human relevance framework; Carcinogenicity; Nasal cancer

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

DNA-damage effect of polycyclic aromatic hydrocarbons from urban area, evaluated in lung fibroblast cultures

Keywords: سرطان زایی; PM2.5; PM2.5-10; Comet assay; PAHs; Mobile sources; Carcinogenicity; Genotoxicity;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

INTEGRATION OF QSAR AND SAR METHODS FOR THE MECHANISTIC INTERPRETATION OF PREDICTIVE MODELS FOR CARCINOGENICITY

Keywords: سرطان زایی; Counter propagation artificial neural network; mechanistic interpretation of model; carcinogenicity; (quantitative) structure-activity relationships; structural alerts; Toxtree application; Dragon descriptors; Kohonen maps; non-congeneric chemicals

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Identification of molecular signatures predicting the carcinogenicity of polycyclic aromatic hydrocarbons (PAHs)

Keywords: سرطان زایی; Polycyclic aromatic hydrocarbons (PAHs); Carcinogenicity; Microarray; Molecular signature

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Development of classification and regression based QSAR models to predict rodent carcinogenic potency using oral slope factor

Keywords: سرطان زایی; OSF; Carcinogenicity; QSAR; OECD; LDA; PDD

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Development of a unit risk factor for nickel and inorganic nickel compounds based on an updated carcinogenic toxicity assessment

Keywords: سرطان زایی; Nickel; Carcinogenesis; Carcinogenicity; Cancer; Lung; Respiratory; Mortality; Incidence; Toxicity; Inhalation;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Photo catalogue for the classification of foci in the BALB/c 3T3 cell transformation assay

Keywords: سرطان زایی; Cell transformation assay; BALB/c 3T3 cell line; Carcinogenicity; Transformed foci; Photo catalogue

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Fumonisin B1 and the kidney: Modes of action for renal tumor formation by fumonisin B1 in rodents

Keywords: سرطان زایی; AP; aminopentol; aSMase; acid sphingomyelinase; FB1; fumonisin B1; JNK; c-Jun N-terminal kinase; CYP; cytochrome P450 superfamiliy; ERK; extracellular regulated kinase; GCS; glucosylceramide synthase; GSH; glutathione; HFB1; hydrolyzed FB1; MAPK; mitogen-

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

Development of a cancer-based chronic inhalation reference value for hexavalent chromium based on a nonlinear-threshold carcinogenic assessment

Keywords: سرطان زایی; Chromium; Hexavalent; Carcinogenicity; Cancer; Lung; Risk; Toxicity; Inhalation; Nonlinear; Threshold;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2012 سفارش ترجمه

First report on development of quantitative interspecies structure–carcinogenicity relationship models and exploring discriminatory features for rodent carcinogenicity of diverse organic chemicals using OECD guidelines

Keywords: سرطان زایی; Carcinogenicity; Interspecies correlation; Quantitative structure–activity relationship; Organization for Economic Cooperation and Development; Chemicals

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2012 سفارش ترجمه

DEHP: Genotoxicity and potential carcinogenic mechanisms-A review

Keywords: سرطان زایی; ADME; absorption, distribution, metabolism and elimination; CAR; constitutive androstane receptor; CERHR; NTP Center for the Evaluation of Risks to Human Reproduction; CHO; Chinese hamster ovary; CYP; cytochrome p450; CpG; cytosine guanine dinucleotide; D

دانلود رایگان متن کامل مقاله ISI 76 صفحه سال انتشار : 2012 سفارش ترجمه

Asphalt fume dermal carcinogenicity potential: I. dermal carcinogenicity evaluation of asphalt (bitumen) fume condensates

Keywords: سرطان زایی; Asphalt; Bitumen; Fume condensate; Dermal; Carcinogenicity; Irritation; Polycyclic aromatic hydrocarbons; Middle distillates; Initiation-promotion

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Improved in silico prediction of carcinogenic potency (TD50) and the risk specific dose (RSD) adjusted Threshold of Toxicological Concern (TTC) for genotoxic chemicals and pharmaceutical impurities

Keywords: سرطان زایی; TTC; Threshold of toxicological concern; Genotoxic; Mutagenic; Impurities; QSAR; SAR; TD50; Pharmaceuticals; Food contact substances; RSD; Carcinogenicity;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Development and application of a skin cancer slope factor for exposures to benzo[a]pyrene in Soil

Keywords: سرطان زایی; Polycyclic aromatic hydrocarbons (PAHs); Benzo[a]pyrene; Carcinogenicity; Human health risk assessment; Dermal exposure; Soil; Skin cancer;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Safer alternatives assessment: the Massachusetts process as a model for state governments

Keywords: سرطان زایی; Alternatives assessment; Carcinogenicity; DEHP; Life cycle thinking; PBT; Plasticizers; PVC; Reproductive toxicity; Resilient flooring; Safer chemicals; Toxic chemicals

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

RITA—Registry of Industrial Toxicology Animal data: The application of historical control data for Leydig cell tumors in rats

Keywords: سرطان زایی; Leydig cell tumor; Interstitial cell adenoma; Leydig cell adenoma; Leydig cell carcinoma; Interstitial cell carcinoma; Interstitial cell tumor; Testis; Testes; Rat; Rodent; Carcinogenicity testing; Carcinogenicity; Oncogenicity; Registry of Industrial Tox

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Evaluation of a multi-endpoint assay in rats, combining the bone-marrow micronucleus test, the Comet assay and the flow-cytometric peripheral blood micronucleus test

Keywords: سرطان زایی; Genotoxicity; Carcinogenicity; Comet assay; Bone-marrow micronucleus; Peripheral blood micronucleus; Flow cytometry; 2-Acetylaminofluorene; Benzo[a]pyrene; Carbendazim; Cyclophosphamide; Dimethylnitrosamine; Ethyl methanesulfonate; Ethyl nitrosurea; Mitom

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2011 سفارش ترجمه

In vitro genotoxicity data of nanomaterials compared to carcinogenic potency of inorganic substances after inhalational exposure

Keywords: سرطان زایی; Nanomaterials; Genotoxicity; In vitro; Carcinogenicity; Lung; In vivo

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2011 سفارش ترجمه

Evaluation of carcinogenicity studies of medicinal products for human use authorised via the European centralised procedure (1995–2009)

Keywords: سرطان زایی; Medicinal products; Carcinogenicity; Rodents

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2011 سفارش ترجمه

A review of mammalian carcinogenicity study design and potential effects of alternate test procedures on the safety evaluation of food ingredients

Keywords: سرطان زایی; Carcinogenicity; Study design; Food ingredients

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2011 سفارش ترجمه

Morphological cell transformation of Syrian hamster embryo (SHE) cells by the cyanotoxin, cylindrospermopsin

Keywords: سرطان زایی; Cylindrospermopsin (CYN); Cyanotoxin; Low-dose effects; Carcinogenicity; Syrian hamster embryo (SHE); Cell transformation

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Pooled analysis of studies on DNA adducts and dietary vitamins

Keywords: سرطان زایی; Biomarkers; Carcinogenicity; Molecular epidemiology

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

SMILES-based optimal descriptors: QSAR modeling of carcinogenicity by balance of correlations with ideal slopes

Keywords: سرطان زایی; QSAR; Carcinogenicity; Optimal descriptor; Balance of correlations

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

SKH-1 mouse skin painting: A short-term assay to evaluate the tumorigenic activity of cigarette smoke condensate

Keywords: سرطان زایی; SKH-1; Cigarette; Smoke; Condensate; Carcinogenicity; Skin painting

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

In silico approaches to predicting cancer potency for risk assessment of genotoxic impurities in drug substances

Keywords: سرطان زایی; Genotoxic; Impurities; In silico; Carcinogenicity; Threshold of toxicological concern; Pharmaceutical; TD50; Cancer potency;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

A Bayesian statistical analysis of mouse dermal tumor promotion assay data for evaluating cigarette smoke condensate

Keywords: سرطان زایی; Bayesian analysis; Dermal tumor promotion; Cigarette smoke condensate; Carcinogenicity;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Toxicity and carcinogenicity studies of methylene blue trihydrate in F344N rats and B6C3F1 mice

Keywords: سرطان زایی; Methylene blue trihydrate; Methemoglobin; Chronic toxicity; Carcinogenicity

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Toxicity prediction of compounds from turmeric (Curcuma longa L)

Keywords: سرطان زایی; Turmeric; Toxicity; Mutagenicity; Carcinogenicity; Hepatotoxicity

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

A quantitative assessment of the carcinogenicity of hexavalent chromium by the oral route and its relevance to human exposure

Keywords: سرطان زایی; Chromium; Hexavalent chromium; Cr6+; Cr(VI); Carcinogenicity; Cancer potencyABW, animal body weight; BMD, benchmark dose; BMDL, benchmark dose lower confidence interval; BMDS, USEPA’s benchmark dose software; HBW, human body weight; HED, human equivalent

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

3-Methylcholanthrene (3-MC) and 4-chlorobiphenyl (PCB3) genotoxicity is gender-related in Fischer 344 transgenic rats

Keywords: سرطان زایی; Polychlorinated biphenyl, PCB3; 3-methylcholanthrene, 3-MC; Gender difference; Genotoxicity; Biotransformation; Carcinogenicity

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Genotoxicity and carcinogenicity testing of pharmaceuticals: Correlations between induction of DNA lesions and carcinogenic activity

Keywords: سرطان زایی; Pharmaceuticals; DNA adducts; DNA strand breaks; DNA repair synthesis; Carcinogenicity

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2010 سفارش ترجمه

The transgenic mouse assay as an alternative test method for regulatory carcinogenicity studies—Implications for REACH

Keywords: سرطان زایی; REACH; Carcinogenicity; Transgenic mice; Alternative models; High production volume chemicals; Genotoxicity; ICH; NTP; HESI; Two-year rodent bioassay

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

PGRMC1 (progesterone receptor membrane component 1): A targetable protein with multiple functions in steroid signaling, P450 activation and drug binding

Keywords: سرطان زایی; Progesterone; P450 proteins; Cholesterol; Carcinogenicity; ChemotherapyInsig, insulin-induced gene; PAIR-BP1, plasminogen activator inhibitor mRNA binding protein; PGRMC1, progesterone receptor membrane component 1; Scap, SREBP cleavage activating protein

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

ECETOC workshop on the biological significance of DNA adducts: Summary of follow-up from an Expert Panel Meeting

Keywords: سرطان زایی; DNA adducts; Mutagenesis; Thresholds; Genotoxicity; Carcinogenicity; Dose–response; Mode of action; Risk assessment; Workshop

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Assessment of the environmental toxicity and carcinogenicity of tungsten-based shot,

Keywords: سرطان زایی; Tungsten; Alloys; Environmental toxicity; Carcinogenicity; Shot

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Carcinogenesis studies of cresols in rats and mice

Keywords: سرطان زایی; Carcinogenicity; Cresols; m-Cresol; p-Cresol; Forestomach papilloma; Renal tubule adenoma

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Modifying effects of prepubertal exposure to potassium perchlorate and tetrabromobisphenol A on susceptibility to N-bis(2-hydroxypropyl)nitrosamine- and 7,12-dimethylbenz(a)anthracene-induced carcinogenesis in rats

Keywords: سرطان زایی; Potassium perchlorate; Tetrabromobisphenol A; Rat; Carcinogenicity; Juvenile toxicity;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Assessment of genomic instability in normal and diabetic rats treated with metformin

Keywords: سرطان زایی; Diabetes; Metformin; Oxidative stress; Chromosomal aberrations; Micronuclei; Carcinogenicity

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Use of rasH2 transgenic mice for carcinogenesis testing of medical implants

Keywords: سرطان زایی; Carcinogenicity; Transgenic; rasH2; Medical device; Animal model; Mouse; Pathology

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Carcinogenic effect of arsenate in C57BL/6J/Han mice and its modulation by different dietary selenium status

Keywords: سرطان زایی; Arsenate; Carcinogenicity; Selenium; Diet; Drinking water; Mouse

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Assessment of the genotoxic and carcinogenic risks of p-nitrophenol when it is present as an impurity in a drug product

Keywords: سرطان زایی; p-Nitrophenol; Paranitrophenol; Nitrophenol; Genotoxicity; Carcinogenicity; Hazard identification; Impurity; Drug product; Exposure

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Monoarylamines in the general population – A cross-sectional population-based study including 1004 Bavarian subjects

Keywords: سرطان زایی; Monoarylamines; General population; Reference values; Carcinogenicity

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2009 سفارش ترجمه