ATF4 regulates CCL2 expression to promote endometrial cancer growth by controlling macrophage infiltration
Keywords: ATF4; Unfolded protein response; Endometrial cancer; CCL2;
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Selective inhibition of BET proteins reduces pancreatic damage and systemic inflammation in bile acid- and fatty acid ethyl ester- but not caerulein-induced acute pancreatitis
Keywords: Acute pancreatitis; Epigenetics; BET inhibition; Drug discovery; AP; acute pancreatitis; AUC; area under the curve; BET proteins; bromodomain and extra-terminal proteins; CCL2; chemokine (C-C motif) ligand 2; CER-AP; caerulein-induced AP; Cmax; peak serum
Inflammatory chemokines and their receptors in human visceral leishmaniasis: Gene expression profile in peripheral blood, splenic cellular sources and their impact on trafficking of inflammatory cells
Keywords: VL; visceral leishmaniasis; CXCL10; C-X-C motif chemokine ligand 10; CXCL9; C-X-C motif chemokine ligand 9; CXCL8; C-X-C motif chemokine ligand 8; CCL5; chemokine (C-C motif) ligand 5; CCL2; chemokine (C-C motif) ligand 2; CX3CR1; CX3C chemokine receptor
Quantum chemical and kinetic study of the CCl2 self-recombination reaction
Keywords: CCl2; C2Cl4; Quantum-chemical calculations; Statistical adiabatic channel model/classical trajectory calculations; Recombination reactions;
Tumor necrosis factor-alpha inhibitors suppress CCL2 chemokine in monocytes via epigenetic modification
Keywords: RA; rheumatoid arthritis; TNF-α; tumor necrosis factor-alpha; MCP-1; chemoattractant protein-1, also called CCL2; HAT; histone acetyltransferase; HDAC; histone deacetylase; IL; interleukin; LPS; lipopolysaccharide; ELISA; Enzyme-linked immunosorbent assa
Anakinra reduces blood pressure and renal fibrosis in one kidney/DOCA/salt-induced hypertension
Keywords: ASC; apoptosis-associated speck-like protein containing a (CARD); BP; blood pressure; CARD; caspase activation and recruitment domain; CCL2; chemokine ligand 2; CCL5; chemokine ligand 5; cDNA; complementary DNA; DAMP; danger-associated molecular pattern;
Minocycline prevents cerebral malaria, confers neuroprotection and increases survivability of mice during Plasmodium berghei ANKA infection
Keywords: CM; cerebral malaria; ECM; experimental cerebral malaria; CXCL10; C-X-C-motif ligand 10; CCL5; C-C motif ligand 5; CCL2; C-C motif ligand 2; CXCR3; C-X-C-motif receptor 3; CCR2; C-C chemokine receptor type 2; Plasmodium berghei; Minocycline; Cerebral mala
THP-1 and human peripheral blood mononuclear cell-derived macrophages differ in their capacity to polarize in vitro
Keywords: ACTB; β-actin; CCL2; chemokine (C-C motif) ligand 2; CCL18; chemokine (C-C motif) ligand 18; CCL22; chemokine (C-C motif) ligand 22; CCR7; chemokine (C-C motif) receptor 7; CD; cluster of differentiation; COX2; cytochrome C oxidase-2; IFNγ; interferon-Î
Danshen improves survival of patients with colon cancer and dihydroisotanshinone I inhibit the proliferation of colon cancer cells via apoptosis and skp2 signaling pathway
Keywords: NHIRD; National Health Insurance Research Database; NHI; National Health Insurance; CRC; Colorectal cancer; Skp2; S-phase kinase-associated protein 2; CCL2; CC chemokine ligand 2; TAMs; tumor-associated macrophages; TCM; Traditional Chinese Medicine; FHPs
Transgenic mice with increased astrocyte expression of CCL2 show altered behavioral effects of alcohol
Keywords: 2BC; two-bottle-choice; ANOVA; analysis of variance; CCL2; chemokine ligand 2; CIE; chronic intermittent vapor exposure; ELISA; enzyme-linked immunosorbent assay; GFAP; glial fibrillary acidic protein; huGFAP; human glial fibrillary acidic protein; mRNA;
Novel peptidyl α-aminoalkylphosphonates as inhibitors of hepatitis C virus NS3/4A protease
Keywords: Hepatitis C virus; NS3/4A protease; Serine protease inhibitors; Peptidyl phosphonates; Boc-Oic-OH; Boc-L-octahydroindole-2-carboxylic acid; Boc-Pip-OH; N-Boc-L-pipecolinic acid; CCR2; CC chemokine receptor 2; CCL2; CC chemokine ligand 2; CCR5; CC chemokin
FAP positive fibroblasts induce immune checkpoint blockade resistance in colorectal cancer via promoting immunosuppression
Keywords: Colorectal cancer; Cancer-associated fibroblast; Fibroblast activation protein-alpha; Immune checkpoint blockade; CCL2;
Mesenchymal stromal cell-based therapies reduce obesity and metabolic syndromes induced by a high-fat diet
Keywords: Acta2; smooth muscle aortic alpha-actin; Adipoq; adiponectin; Alb; albumin; Ccl2; chemokine (C-C Motif) ligand 2; Col1a1; Collagen, type I, alpha 1; Col1a2; Collagen, type I, alpha 2; Fn1; fibronectin; G6pc; glucose-6-phosphatase catalytic-subunit; Glut2;
Basophils, high-affinity IgE receptors, and CCL2 in human anaphylaxis
Keywords: Anaphylaxis; basophils; CD63 activation; FcεRI expression; CCL2; serum tryptase; CPA3; Carboxypeptidase A3; CRTH2; Chemoattractant receptor-homologous molecule expressed on TH2 lymphocytes; DBPCFC; Double-blind, placebo-controlled food challenge; ED; E
Inhibition of human cytomegalovirus replication by tricin is associated with depressed CCL2 expression
Keywords: Cytomegalovirus replication; Tricin; CCL2; CCR2; Anti-inflammatory compound; DMEM; Dulbecco's Modified Eagle's Medium; HCMV; human cytomegalovirus; HEL; human embryonic lung fibroblasts cells; IE; immediate early gene;
Oxidized phospholipids exert a dual effect on bile acid-induced CCL2 expression in pancreatic acini
Keywords: Inflammatory gene expression; Pancreatic acinar cells; PPARγ; Oxidized phospholipids; TLR4; CCL2; chemokine (C-C motif) ligand 2; FA; fatty acid; JAK; janus kinase; JNK-MAPK; c-Jun NH2-terminal kinase mitogen-activated protein kinase; NF-κB; nuclear fac
Impact of BRAF kinase inhibitors on the miRNomes and transcriptomes of melanoma cells
Keywords: ASNS; asparagine synthetase; AXL; proto-oncogene tyrosine kinase receptor AXL; BRAF; B-Raf proto-oncogene serine/threonine kinase/v-raf murine sarcoma viral oncogene homolog B; CCL2; chemokine C-C motif ligand 2; CE; coexpression coefficient; CHAC1; ChaC
Dual signaling evoked by oxidized LDLs in vascular cells
Keywords: AAPH; 2,2'-azobis(2-amidinopropane) dihydrochloride; AIF; apoptotic inducing factor; AMVN; 2,4-dimethylvaleronitrile; AP-1; activator protein 1; ATF6; activating transcription factor 6; CDE; clathrin-dependent endocytosis; CCL2; chemokine ligand 2 (or MCP
Alternative splicing of hepatitis B virus: A novel virus/host interaction altering liver immunity
Keywords: HBV; Liver fibrosis; HBSP; Alternate splicing; Macrophages; CCL2;
Lactate produced during labor modulates uterine inflammation via GPR81Â (HCA1)
Keywords: CCL2; chemokine; chorioamnionitis; cytokine; endotoxin; GPR81; inflammation; interleukin; interleukin-1; interleukin-6; labor; lactate; lactic acid; lipopolysaccharide; PGHS2; mouse; myometrium; parturition; preterm labor; pyruvate; spontaneous labor;
The translocator protein (18Â kDa) and its role in neuropsychiatric disorders
Keywords: 3α-HSD; 3α-hydroxysteroid dehydrogenase; 3β-HSD; 3β-hydroxysteroid dehydrogenase/Î5âÎ4; AIF; apoptosis inducing factor; AD; Alzheimer's disease; ANT; adenine nucleotide translocator; AP-1; activator protein 1; APAF-1; apoptotic peptidase activat
Preliminary reportCCL2 gene polymorphism is associated with post-transplant diabetes mellitus
Keywords: CCL2; CCL5; Polymorphism; Kidney; Graft; Post-transplant diabetes mellitus;
Luteolin inhibits recruitment of monocytes and migration of Lewis lung carcinoma cells by suppressing chemokine (C-C motif) ligand 2 expression in tumor-associated macrophage
Keywords: TAMs; IL-4; Luteolin; STAT6; CCL2; Migration;
CC chemokine ligand 2 and CXC chemokine ligand 8 as neutrophil chemoattractant factors in canine idiopathic polyarthritis
Keywords: IPA; idiopathic polyarthritis; SF; synovial fluid; PMNs; polymorphonuclear leukocytes; CCL2; CC chemokine ligand 2; hRA; human rheumatoid arthritis; CCR2; chemokine (CC motif) receptor 2; CXCL8; CXC chemokine ligand 8; OA; osteoarthropathy; PBS; phosphate
Stimulation of nuclear receptor REV-ERBs regulates tumor necrosis factor-induced expression of proinflammatory molecules in C6 astroglial cells
Keywords: REV-ERB; Astrocytes; Tumor necrosis factor; Matrix metalloprotease-9; CCL2; HDAC3;
Pro-inflammatory chemokines CCL2, chemerin, IP-10 and RANTES in human serum during an oral lipid tolerance test
Keywords: Inflammation; Chemokine; CCL2; Chemerin; IP-10; RANTES; Oral lipid tolerance test; Hypertriglyceridemia
Paquinimod reduces skin fibrosis in tight skin 1 mice, an experimental model of systemic sclerosis
Keywords: α-SMA; α-smooth-muscle-actin; CCL2; chemokine (C-C motif) ligand 2; CCR2; chemokine receptor 2; Col1a1; collagen 1a1; Col1a2; collagen 1a2; Col3a1; collagen 3a1; Ctgf; connective tissue growth factor; DAMP; damage-associated molecular pattern; ECM; extr
High expression of chemokine CCL2 is associated with recurrence after surgery in clear-cell renal cell carcinoma
Keywords: Clear-cell renal cell carcinoma; CCL2; Prognostic biomarker; Recurrence-free survival; Nomogram;
The chemokine (C-C motif) ligand protein synthesis inhibitor bindarit prevents cytoskeletal rearrangement and contraction of human mesangial cells
Keywords: AngII; angiotensin II; CCL2; Chemokine (C-C motif) ligand-2; ECM; extracellular matrix; ET1; endothelin 1; FCS; fetal calf serum; GMCs; glomerular mesangial cells; HRMCs; human renal mesangial cells; MAPK; mitogen-activated protein kinases; MCs; mesangial
Different forms of alpha-1 antitrypsin and neutrophil activation mediated by human anti-PR3 IgG antibodies
Keywords: A1AT; alpha 1 antitrypsin; ANCA; antineutrophil cytoplasmic antibodies; CACNA1D; calcium channel voltage-dependent l type alpha 1d subunit; CACNB2; calcium channel voltage-dependent beta 2 subunit; CCL2; chemokine (C-C motif) ligand 2; CXCL2; chemokine (C
ReviewMyelin and macrophages in the PNS: An intimate relationship in trauma and disease
Keywords: AIDP; acute inflammatory demyelinating polyneuropathy; AMAN; acute motor axonal neuropathy; BC; Büngner cells; CCL2; monocyte chemoattractant protein-1; CIDP; chronic inflammatory, demyelinating polyradiculopathy; CMT; Charcot-Marie-Tooth; CNS; centr
Voluntary exercise blocks Western diet-induced gene expression of the chemokines CXCL10 and CCL2 in the prefrontal cortex
Keywords: CREB; cAMP response element binding protein; CNS; central nervous system; CCL2; chemokine (C-C Motif) ligand 2; CCR2; chemokine (C-C Motif) receptor 2; CTRL; control; CXCL10; C-X-C motif chemokine 10; COX-2; cyclooxygenase 2; EPM; elevated plus maze; EX R
Enhanced Ccl2-Ccr2 signaling drives more severe choroidal neovascularization with aging
Keywords: Aging; Choroid; Retina; Myeloid cells; CCL2; Choroidal neovascularization;
General control non-derepressible 2 (GCN2) in T cells controls disease progression of autoimmune neuroinflammation
Keywords: General control non-derepressible 2 (GCN2); Chemokines; CCL2; Regulatory T cell (Treg); Experimental autoimmune encephalomyelitis (EAE);
Cancer development, chemoresistance, epithelial to mesenchymal transition and stem cells: A snapshot of IL-6 mediated involvement
Keywords: Cytokine; IL-6; Cancer stem cell; Chemoresistance and EMT; MAPK; mitogen-activated protein kinases; STAT3; signal transducer and activator of transcription 3; gp130; glycoprotein 130; C/EBP; CCAAT/enhancer-binding protein; JAK; Janus kinase; PI3K; phospho
Research ArticleIL-23 prevents IL-13-dependent tissue repair associated with Ly6Clo monocytes in Entamoeba histolytica-induced liver damage
Keywords: IL; interleukin; CCR2; C-C chemokine receptor 2; mAb; monoclonal antibody; E. histolytica; Entamoeba histolytica; ALA; amebic liver abscess; TNF; tumor necrosis factor; Th; T helper; CCL2; C-C chemokine ligand 2; Ly6C; lymphocyte antigen 6C; NOS2; nitric
Direct and indirect pharmacological modulation of CCL2/CCR2 pathway results in attenuation of neuropathic pain - In vivo and in vitro evidence
Keywords: ANOVA; analysis of variance; CCI; chronic constriction injury; CCL2; CC chemokine ligand 2; CCR2; CC chemokine receptor 2; CD40; cluster of differentiation 40; DMSO; dimethyl sulfoxide; GFAP; glial fibrillary acidic protein; HPRT; hypoxanthine-guanine pho
Effect of CCL2 on BV2 microglial cell migration: Involvement of probable signaling pathways
Keywords: CCL2; CCR2; BV2 cells; Migration; Intracellular signaling pathways;
Role of chemokine pathways in hepatobiliary cancer
Keywords: Angiogenesis; Macrophages; CCR2; CCL2; CXCR4; CXCL12
CCL2–CCR2 signaling promotes hepatic ischemia/reperfusion injury
Keywords: CCL2; CCR2; Ischemia/reperfusion; Neutrophils; Kupffer cells
The P72R Polymorphism of p53 Predisposes to Obesity and Metabolic Dysfunction
Keywords: p53; obesity; diabetes; islet hypertrophy; NAFLD; lipid metabolism; inflammation; Pck1; Ccl2; Tnf; Npc1l1
Overexpression of the monocyte chemokine CCL2 in dorsal root ganglion neurons causes a conditioning-like increase in neurite outgrowth and does so via a STAT3 dependent mechanism
Keywords: CCL2; MCP-1; DRG; Regeneration; Macrophage; Neuroinflammation; STAT3
Increased percentage of Th17 cells in peritoneal fluid is associated with severity of endometriosis
Keywords: TGF-β; transforming growth factor β; IL-6; interleukin-6; STAT3; signal-transducer and activator of transcription; RORα; retinoid acid-related orphan receptor α; ICAM-1; intercellular adhesion molecule-1; MCP-1; monocyte chemoattractant protein-1; PGE
Synthesis, biological evaluation and molecular modeling of a novel series of 7-azaindole based tri-heterocyclic compounds as potent CDK2/Cyclin E inhibitors
Keywords: Cyclin-dependent kinase 2; Kinase inhibitors; Anti-tumor agent; 1H-pyrrolo[2,3-b]pyridine; [3Â +Â 2] cycloaddition; 1,4-Triazole; 1,5-Triazole; 3D-QSAR CoMFA; CCR2; CC chemokine receptor 2; CCL2; CC chemokine ligand 2; CCR5; CC chemokine receptor 5;
Glycans Related to the CA19-9 Antigen Are Increased in Distinct Subsets of Pancreatic Cancers and Improve Diagnostic Accuracy Over CA19-9
Keywords: Biomarkers; Sialyl-Lewis A; Antibody Arrays; Lectins; AUC; area under the ROC curve; BSA; bovine serum albumin; CA19-9; cancer antigen 19-9; CCL2; Coprinopsis cinerea lectin 2; LacNAc; N-acetyl-lactosamine; PBS; phosphate-buffered saline; ROC; receiver op
Pleural Effusions from Patients with Mesothelioma Induce Recruitment of Monocytes and Their Differentiation into M2 Macrophages
Keywords: CCL2; Mesothelioma; Pleural effusions; Macrophages; M-CSF;
Microvesicles enhance the mobility of human diabetic adipose tissue-derived mesenchymal stem cells in vitro and improve wound healing in vivo
Keywords: Microvesicles; Mesenchymal stem cells; Wound healing; Flap mouse model; Diabetes; SDF-1; stromal cell-derived factor 1; CXCR4; C-X-C chemokine receptor type 4; CXCR7; C-X-C chemokine receptor type 7; CCL2; chemokine (CeC motif) ligand 2; ANGPTL4; angiopoi
CCL2 mediates the circadian response to low dose endotoxin
Keywords: Circadian; Suprachiasmatic; Ccl2; Ccr2; Chemokine; Lipopolysaccharide; Immune; Bindarit;
Gu-Ben-Fang-Xiao decoction attenuates sustained airway inflammation by suppressing ER stress response in a murine asthma remission model of respiratory syncytial virus infection
Keywords: GBFXD; GuBenFangXiao decoction; RSV; respiratory syncytial virus; OVA; ovalbumin; ER; endoplasmic reticulum; UPR; unfolded protein response; TCM; traditional Chinese medicine; Mont; montelukast sodium; DEX; dexamethasone; HPLC; high performance liquid chr
In vitro expansion of human cardiac progenitor cells: exploring 'omics tools for characterization of cell-based allogeneic products
Keywords: hCPC; human cardiac stem/progenitor cells; CSC; cardiac stem cells; CM; cardiomyocytes; ATMP; advanced therapy medicinal product; 2DE; 2-D electrophoresis; MS; mass spectrometry; MALDI; matrix-assisted laser desorption/ionization; IGF-I; insulin-like grow