Keywords: CcO، cytochrome c oxidase; Small Intestine; Cancer; Malignancy; Gene ExpressionACEC, aberrant crypt containing endocrine cell cluster; APC, adenomatous polyposis coli; Bmi1, B lymphoma Mo-MLV insertion region 1 homolog; CCO, cytochrome c oxidase; ChgA, chromogranin A; DCLK1, double
مقالات ISI CcO، cytochrome c oxidase (ترجمه نشده)
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Keywords: CcO، cytochrome c oxidase; BEC, blood ethanol concentrations; E2, 17β-estradiol; EW, ethanol withdrawal; Vt.E + Co-Q10, Vitamin E + Co-enzyme Q10; CcO, cytochrome c oxidase; MDA, malondialdehyde; ROS, reactive oxygen species; TBARS, thiobarbituric acid reactive substancesAntioxidan
Keywords: CcO، cytochrome c oxidase; ET, electron transfer; PS-I/II, photosystem I/II; FeS, iron–sulfur; FNR, ferredoxin-NADPH reductase; NAD, nicotinamide adenosine dinucleotide; HSAB, hard-soft acid-base; CcO, cytochrome c oxidase; T1/2Cu, type 1/2 copper protein; SOD, superoxide dismutase
Keywords: CcO، cytochrome c oxidase; PD, Parkinson's disease; PDD, Parkinson's disease with depressive-like behavior; LHb, The lateral habenula; SN, substantia nigra; HRP, horseradish peroxidase; FST, forced swim test; OFT, open-field test; CCO, cytochrome c oxidase; MFB, medial forebrain bu
Keywords: CcO، cytochrome c oxidase; Metal pollution; Fish; Chronic exposure; Biomarkers; Gene transcription; Functional responseANOVA, Analysis of variance; BHT, Butylated hydroxytoluene; BSA, Bovine serum albumin; CAT, Catalase; CCO, Cytochrome c oxidase; cDNA, Complementary DNA; CDNB, Chl
Mitochondria-targeted heme oxygenase-1 induces oxidative stress and mitochondrial dysfunction in macrophages, kidney fibroblasts and in chronic alcohol hepatotoxicity
Keywords: CcO، cytochrome c oxidase; HO-1, Heme Oxygenase-1; ROS, Reactive Oxygen Species; NPR, NADPH cytochrome P 450 reductase; CcO, cytochrome c oxidase; ER, Endoplasmic reticulum; DCFH-DA, Dichlorofluorescein diacetateHeme oxygenase-1; Mitochondrial targeting; Cytochrome c Oxidase; Heme
Redox biology of hydrogen sulfide: Implications for physiology, pathophysiology, and pharmacology
Keywords: CcO، cytochrome c oxidase; ARE, Antioxidant response element; CO, Carbon monoxide; CBS, Cystathionine-β-synthase; CGL, Cystathionine-γ-lyase; CcO, Cytochrome c oxidase; GSH, Glutathione; HSP, Heat shock protein; H2S, Hydrogen sulfide; HIF, Hypoxic inducible factor; IL-1β, Interleuk
Design and use of photoactive ruthenium complexes to study electron transfer within cytochrome bc1 and from cytochrome bc1 to cytochrome c
Keywords: CcO، cytochrome c oxidase; Cc, cytochrome c; yCc, yeast Cc; cyt bc1, cytochrome bc1; CcO, cytochrome c oxidase; 2Fe2S, Rieske iron–sulfur center; ISP, iron–sulfur protein; bpy, 2,2′-bipyridine; dmb, 4,4′-dimethyl-2,2′-bipridine; bpz, 2,2′-bipyrazine; bpd, 3,3′-bipyridazine; qpy, 2,
Age-related decline of the cytochrome c oxidase subunit expression in the auditory cortex of the mimetic aging rat model associated with the common deletion
Keywords: CcO، cytochrome c oxidase; CcO, cytochrome c oxidase; mtDNA, mitochondrial DNA; CD, common deletion; d-gal, D-galactose; PGC-1α, peroxisome proliferator-activated receptor-γ coactivator 1α; NRF-1, nuclear respiratory factor 1; TFAM, mitochondrial transcription factor A; AHL, age-re
Dynamic water networks in cytochrome cbb3 oxidase
Keywords: CcO، cytochrome c oxidase; HCO, heme-copper oxidase; MD, molecular dynamics; PLS, proton-loading site; CcO, cytochrome c oxidase; DFT, density functional theory; CcP, cytochrome c peroxidase; pT, proton-transferProton channel; Proton pumping; cbb3-type cytochrome c oxidase; Continu
The roles of Rhodobacter sphaeroides copper chaperones PCuAC and Sco (PrrC) in the assembly of the copper centers of the aa3-type and the cbb3-type cytochrome c oxidases
Keywords: CcO، cytochrome c oxidase; CCCP, carbonylcyanide m-chlorophenylhydrazone; CcO, cytochrome c oxidase; ICP-OES, inductively coupled plasma optical emission spectroscopy; TMPD, N,N,N′,N′-tetramethyl-p-phenylenediaminecbb3-type cytochrome c oxidase; aa3-type cytochrome c oxidase; Coppe
The identity of the transient proton loading site of the proton-pumping mechanism of cytochrome c oxidase
Keywords: CcO، cytochrome c oxidase; CcO, Cytochrome c Oxidase; BNC, Binuclear Center; Glu, Glutamic Acid; Asp, Aspartic Acid; MD, Molecular Dynamics; PLS, Proton-loading SiteProton pump; Heme-copper oxidase; MD simulation; Proton-coupled electron transfer; Continuum electrostatics
The role of mitochondrial membrane potential in ischemic heart failure
Keywords: CcO، cytochrome c oxidase; CcO, cytochrome c oxidase; ROS, reactive oxygen species; MPTP, mitochondrial permeability transition pore; I/R, ischemia/reperfusionHeart ischemia/reperfusion; Cytochrome c oxidase; Mitochondrial membrane potential; Reactive oxygen species; Protein phosph
Time-resolved single-turnover of caa3 oxidase from Thermus thermophilus. Fifth electron of the fully reduced enzyme converts OH into EH state
Keywords: CcO، cytochrome c oxidase; BNC, binuclear catalytic center; CcO, cytochrome c oxidase; RubiPy, tris(2,2′-bipyridyl) ruthenium; CHES, 2-(N-cyclohexylamino)ethane sulfonic acid; DM, n-dodecyl-β-d-maltoside; MOPS, 3-(N-morpholino)propanesulfonic acid; TMPD, N,N,N′,N′-tetramethyl-1,4-p
The medium reorganization energy for the charge transfer reactions in proteins
Keywords: CcO، cytochrome c oxidase; BRC, bacterial reaction center of photosynthesis; CcO, cytochrome c oxidase; cyt c, cytochrome c; ESP, electrostatic potential (charges); MADH, methylamine dehydrogenase; MO, molecular orbital; pdb, protein data bank; THI, tetrahedral intermediateProtein
A theoretical investigation of the functional role of the axial methionine ligand of the CuA site in cytochrome c oxidase
Keywords: CcO، cytochrome c oxidase; CcO, cytochrome c oxidase; MD, Molecular dynamics; QM, Quantum mechanics; MM, Molecular mechanics; Cyt c, cytochrome c; MOE, molecular operating environmentTransition metal binding protein; Redox potential; Electron transfer; Electronic structure; Structu
Cytochrome c oxidase loses catalytic activity and structural integrity during the aging process in Drosophila melanogaster
Keywords: CcO، cytochrome c oxidase; CcO, cytochrome c oxidase; O2-, superoxide anion radical; H2O2, hydrogen peroxide; ETC, electron transport chainCytochrome c oxidase; Complex IV subunits; Electron transport chain; Mitochondria; Aging; Oxidative stress
Mitochondrial respiration and membrane potential are regulated by the allosteric ATP-inhibition of cytochrome c oxidase
Keywords: CcO، cytochrome c oxidase; BSA, bovine serum albumin; CCCP, carbonyl cyanide m-chlorophenylhydrazone; CcO, cytochrome c oxidase; ∆Ψm, mitochondrial membrane potential; PEP, phosphorenolpyruvate; PK, pyruvate kinase; ROS, reactive oxygen species; TPP+, tetraphenyl phosphonium ionCyt
Kinetic model of the inhibition of respiration by endogenous nitric oxide in intact cells
Keywords: CcO، cytochrome c oxidase; NO, nitric oxide; NOS, NO synthase; CcO, cytochrome c oxidase; O2, oxygen; CN−, cyanide; CO, carbon monoxide; iNOS, inducible NOS; DMEM, Dulbecco's modified Eagle's medium; Tet-iNOS 293, tetracycline-inducible iNOS-expressing HEK 293 cells; S-EITU, S-ethy
A suggested role for mitochondria in Noonan syndrome
Keywords: CcO، cytochrome c oxidase; CcO, cytochrome c oxidase; Cytc, cytochrome c; CS, citrate synthase; ETC, electron transport chain; IMS, intermembrane space; KD, knockdown; NS, Noonan syndrome; OxPhos, oxidative phosphorylation; WT, wild-typeCardio-facio-cutaneous syndrome; Cytochrome c
Time-resolved OH → EH transition of the aberrant ba3 oxidase from Thermus thermophilus
Keywords: CcO، cytochrome c oxidase; CcO, cytochrome c oxidase; DM, (dodecyl L-D-maltoside); Em, midpoint redox potential; RubiPy, tris(2,2′-bipyridyl) ruthenium; TMPD, N,N,N,N-tetramethyl-p-phenylenediamine; Tris, tris(hydroxymethyl)aminomethane; τ, time constantCatalytic cycle; Cytochrome
Antioxidants activities and concentration of selenium, zinc and copper in preterm and IUGR human placentas
Keywords: CcO، cytochrome c oxidase; IUGR, intrauterine growth restriction; ROS, reactive oxygen species; Cu–Zn SOD, superoxide dismutase; GSH, glutathione; GSH-Px, glutathione peroxidase; GSSG, glutathione disulfide; CCO, cytochrome c oxidase; G6PDH, dehydrogenase glucose-6-phosphate; Zn, z
Differential impact of copper deficiency in rats on blood cuproproteins
Keywords: CcO، cytochrome c oxidase; AAS, flame atomic absorption spectroscopy; CCS, copper chaperone for superoxide dismutase; CCO, cytochrome c oxidase; COX IV, subunit four of cytochrome c oxidase; Cp, ceruloplasmin; CuA, copper-adequate; CuD, copper-deficient; DAO, diamine oxidase; ESOD,
Mechanism and energetics by which glutamic acid 242 prevents leaks in cytochrome c oxidase
Keywords: CcO، cytochrome c oxidase; CcO, cytochrome c oxidase; G−/g− and GH/gH, deprotonated and protonated forms of glutamic acid 242; g and G, “down” and “up” conformational isomers of Glu-242 where the side chain points towards the D-pathway and towards the active site/proton-loading sit
Respiratory metabolism in the embryonic axis of germinating pea seed exposed to cadmium
Keywords: CcO، cytochrome c oxidase; Cadmium; Germination; Pisum sativum; RespirationADH, alcohol dehydrogenase; CCO, cytochrome c oxidase; G6PDH, glucose-6-phosphate dehydrogenase; INADH, alcohol dehydrogenase inactivator; INV-AS, soluble acid invertase; INV-AW, cell wall bound acid inverta
The chemistry of the CuB site in cytochrome c oxidase and the importance of its unique His–Tyr bond
Keywords: CcO، cytochrome c oxidase; pmf, proton motive force; DFT, density functional theory; Em,7, mid-point redox potential at pH 7 relative to NHE; CcO, cytochrome c oxidase; cyt c, cytochrome c; RMSD, root mean square deviation; wt, the model system of the “wild type” structure of the C
Suppression of the inducible form of nitric oxide synthase prior to traumatic brain injury improves cytochrome c oxidase activity and normalizes cellular energy levels
Keywords: CcO، cytochrome c oxidase; trauma; mitochondria; iNOS; cytochrome c oxidase; nitric oxide; ATPANOVA, analysis of variance; CcO, cytochrome c oxidase; EDTA, ethylenediaminetetraacetic acid; EGTA, ethylene glycol-bis(2-aminoethylether)-N,N,N′,N′-tetraacetic acid; ETC, electron transp
Electrostatic control of proton pumping in cytochrome c oxidase
Keywords: CcO، cytochrome c oxidase; CcO, cytochrome c oxidase; BNC, binuclear center; PLS, proton loading siteCytochrome c oxidase; Vectorial proton transport; Redox-coupled proton transport; Proton-pumping mechanism; Binuclear center; Continuum electrostatics
Alterations in mitochondrial respiratory functions, redox metabolism and apoptosis by oxidant 4-hydroxynonenal and antioxidants curcumin and melatonin in PC12 cells
Keywords: CcO، cytochrome c oxidase; CYP2E1, cytochrome P450 2E1; CcO, cytochrome c oxidase; DCFDA, 2′,7′-dichlorofluorescein diacetate; DMNA, dimethylnitrosamine; DNPH, dinitrophenol hydrazine; GSH, glutathione; GST, glutathione S-transferase; 4-HNE, 4-hydroxynonenal; LPO, lipid peroxidatio
Theoretical and computational analysis of the membrane potential generated by cytochrome c oxidase upon single electron injection into the enzyme
Keywords: CcO، cytochrome c oxidase; CcO, cytochrome c oxidase; BNC, binuclear center; PLS, proton-loading site; N-side, negative side of the membrane; P-side, positive side of the membrane; M.P., membrane position; SD, standard deviationParacoccus denitrificans; Cytochrome c oxidase; Electr
Tryptophan 334 oxidation in bovine cytochrome c oxidase subunit I involves free radical migration
Keywords: CcO، cytochrome c oxidase; CcO, cytochrome c oxidase; HPLC, high-performance liquid chromatography; HPLC-ESI/MS/MS, reversed-phase HPLC with electrospray ionization tandem mass spectrometry detection and analysis; MALDI-TOF/MS, matrix-assisted laser desorption ionization time-of-fl
Adverse effects of excessive nitric oxide on cytochrome c oxidase in lenses of hereditary cataract UPL rats
Keywords: CcO، cytochrome c oxidase; CCO, cytochrome c oxidase; GAPDH, glyceraldehyde-3-phosophate dehydrogenase; NO, nitric oxide; iNOS, inducible nitric oxide synthase; NFκB, nuclear factor kappa BCataract; Cytochrome c oxidase; Nitric oxide; Anti-cataract drugs; Calcium
Time-resolved single-turnover of ba3 oxidase from Thermus thermophilus
Keywords: CcO، cytochrome c oxidase; A, ferrous oxy species; CcO, cytochrome c oxidase; DM, dodecyl-β-d-maltoside; F, ferryl species; HEPES, 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; N-side, electrically negative side of the membrane (bacterial cytoplasm); O, fully oxidized species
Knockdown of Human Oxa1l Impairs the Biogenesis of F1Fo-ATP Synthase and NADH:Ubiquinone Oxidoreductase
Keywords: CcO، cytochrome c oxidase; OXPHOS, oxidative phosphorylation system; CcO, cytochrome c oxidase; SDH, succinate:ubiquinone oxidoreductase; CS, citrate synthase; SDHA, 70 kDa flavoprotein subunit of SDH; PDH, pyruvate dehydrogenase; HEK293, human embryonic kidney 293; RNAi, RNA inter
Rates and Equilibrium of CuA to Heme a Electron Transfer in Paracoccus denitrificans Cytochrome c Oxidase
Keywords: CcO، cytochrome c oxidase; CcO, cytochrome c oxidase; ET, electron transfer; MNA, 1-methyl nicotinamide; DM, n-dodecyl-β-d-maltoside
Elementary steps of proton translocation in the catalytic cycle of cytochrome oxidase
Keywords: CcO، cytochrome c oxidase; CcO, cytochrome c oxidase; COMV, “mixed-valence” (two-electron reduced) enzyme ligated by carbon monoxide; P-side, positive side of the membrane (corresponds to the outside of the inner mitochondrial or bacterial membrane); N-side, negative side of the me
Modulation of mitochondrial metabolic function by phorbol 12-myristate 13-acetate through increased mitochondrial translocation of protein kinase Cα in C2C12 myocytes
Keywords: CcO، cytochrome c oxidase; CcO, cytochrome c oxidase; PDH, pyruvate dehydrogenase; PKC, protein kinase C; PMA, phorbol 12-myristate 13-acetate; ROS, reactive oxygen species
Transmembrane proton translocation by cytochrome c oxidase
Keywords: CcO، cytochrome c oxidase; CcO, cytochrome c oxidase; CuA, CuB, copper A and B, respectively; R, CcO with a fully reduced catalytic site (i.e. heme a3 and CuB are both reduced); A, CcO with a reduced catalytic site and with O2 bound to the reduced heme a3; PM, PR, the “peroxy” inte
Combined DFT and electrostatics study of the proton pumping mechanism in cytochrome c oxidase
Keywords: CcO، cytochrome c oxidase; CcO, cytochrome c oxidase; DFT, density functional theory; MeIm, methylimidazole; QM, quantum mechanical; PBE, Poisson–Boltzmann equation; PRD, heme propionate D; SCRF, self-consistent reaction field; The numbering refers to bovine CcOCytochrome c oxidase
Respiratory cytochrome c oxidase can be efficiently reduced by the photosynthetic redox proteins cytochrome c6 and plastocyanin in cyanobacteria
Keywords: CcO، cytochrome c oxidase; CcO, cytochrome c oxidase; Cyt, cytochrome; dRf, 5-deazariboflavin; kbim, bimolecular rate constant; ket′, apparent electron transfer rate constant; kobs, observed pseudo first-order rate constant; Pc, plastocyaninCyanobacteria; Cytochrome c6; Cytochrome
Structural characterization of the PCO/O2PCO/O2 compound of cytochrome c oxidase
Keywords: CcO، cytochrome c oxidase; EPR, electron paramagnetic resonance; CcO, cytochrome c oxidase; PR, PM, PH, PCO/O2PCO/O2, the P species in cytochrome c oxidase formed in the reaction of the fully reduced enzyme with oxygen, formed in the reaction of the mixed-valence enzyme with oxygen
Metal compounds and small molecules activation – case studies
Keywords: CcO، cytochrome c oxidase; ΦΔ, quantum yield of 1O2 formation; Cbl, cobalamin; CcO, cytochrome c oxidase; cyclam, 1,4,7,9-tetraazacyclotetradecane; DNICs, dinitrosyl iron complexes; DTC, dithiocarbamate; dtpa5−, diethylenetriaminepentaacetate; edampda2−, N,N′-bis(2-pyridylmethyl)et