Standard CD44 modulates YAP1 through a positive feedback loop in hepatocellular carcinoma
Keywords: Hepatocellular carcinoma; CD44; YAP; Hippo signaling pathway;
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BMP-2 enhances the migration and proliferation of hypoxia-induced VSMCs via actin cytoskeleton, CD44 and matrix metalloproteinase linkage
Keywords: BMP-2; bone morphogenetic protein 2; VMSCs; vascular smooth muscle cells; ECM; extracellular matrix; MMPs; matrix metalloproteinases; PEX; hemopexin-like C-terminal domain; IP3; inositol phosphatidyl 3; CABG; Coronary Artery Bypass Grafting; CCA; Common C
CD44 collaborates with ERBB2 mediate radiation resistance via p38 phosphorylation and DNA homologous recombination pathway in prostate cancer
Keywords: CD44; ERBB2; p-p38; Homologous recombination; Prostate cancer;
Increase in hyaluronic acid degradation decreases the expression of estrogen receptor alpha in MCF7 breast cancer cell line
Keywords: Estrogen signaling; Hyaluronic acid; Hyaluronidase; Breast cancer; Hormonal therapy resistance; CD44; cluster of differentiation 44; CV; crystal violet; E2; 17β-estradiol; ECM; extracellular matrix; EMT; epithelial-mesenchymal transition; ER; estrogen re
High CD44 expression mediates p62-associated NFE2L2/NRF2 activation in breast cancer stem cell-like cells: Implications for cancer stem cell resistance
Keywords: AKR; aldo-keto reductase; ARE; antioxidant response element; CD44; cluster of differentiation 44; CSC; cancer stem cell; GCLC; glutamate-cysteine ligase catalytic subunit; GPX; glutathione peroxidase; GSH; glutathione; HO-1; heme oxygenase-1; HA; hyaluron
Extracellular matrix component expression in human pluripotent stem cell-derived retinal organoids recapitulates retinogenesis in vivo and reveals an important role for IMPG1 and CD44 in the development of photoreceptors and interphotoreceptor matrix
Keywords: BCAN; Brevican; BrM; Bruch's membrane; CD44; cluster of differentiation 44; Col4A1; Collagen IV; ECM; extracellular matrix; FBS; Fetal bovine serum; FN1; Fibronectin; GCL; ganglion cell layer; HDBR; human developmental biology resource; hESCs; human emb
Substrate stiffness modulates the multipotency of human neural crest derived ectomesenchymal stem cells via CD44 mediated PDGFR signaling
Keywords: Neural crest; Ectomesenchymal stem cells; Substrate stiffness; Multipotency; CD44; PDGFRβ;
CD44 is required for the pathogenesis of experimental crescentic glomerulonephritis and collapsing focal segmental glomerulosclerosis
Keywords: CD44; cell migration; collapsing FSGS; crescentic glomerulonephritis; parietal epithelial cells;
The role of CD44, hyaluronan and NHE1 in cardiac remodeling
Keywords: Cardiac remodeling; Cardiac hypertrophy; Extracellular matrix remodeling; Heart failure; Cardiac fibroblast; CD44; Hyaluronan; NHE-1; Fibrosis; TGF-β;
Aptamer-guided siRNA-loaded nanomedicines for systemic gene silencing in CD-44 expressing murine triple-negative breast cancer model
Keywords: Liposomes; siRNA; Protamine; Aptamers; Cancer stem cell; CD44;
Dual targeting system by supramolecular complex of folate-conjugated methyl-β-cyclodextrin with adamantane-grafted hyaluronic acid for the treatment of colorectal cancer
Keywords: Dual targeting; Folate receptor; CD44; Methylâβâcyclodextrin; Hyaluronic acid; Supramolecular complex;
Expression and shedding of CD44 in the endometrium of women with endometriosis and modulating effects of vitamin D: A randomized exploratory trial
Keywords: Endometriosis; Endometrium; CD44; Vitamin D;
A functional glycoproteomics approach identifies CD13 as a novel E-selectin ligand in breast cancer
Keywords: CD44; HCELL; CD13; sLeX; E-selectin ligand; Breast cancer;
Cyclometalated iridium(III) luminescent complexes in therapy and phototherapy
Keywords: A2058; human metastatic melanoma cell; A2780; human ovarian carcinoma cell; A2780cisR; cisplatin-resistant A2780; A375; human melanoma cell; A549; human lung adenocarcinoma epithelial cell; A549R; cisplatin-resistant A549 cell; Aβ; beta-amyloid; acac; ac
CD44 targeted PLGA nanomedicines for cancer chemotherapy
Keywords: Poly(lactide-co-glycolide); CD44; Hyaluronic acid; Nanoparticle; Chemotherapy;
Cholesterol inhibits hepatocellular carcinoma invasion and metastasis by promoting CD44 localization in lipid rafts
Keywords: Cholesterol; HCC; Metastasis; CD44; Lipid raft;
Original articleExpression profiles of cancer stem cell markers: CD133, CD44, Musashi-1 and EpCAM in the cardiac mucosa-Barrett's esophagus-early esophageal adenocarcinoma-advanced esophageal adenocarcinoma sequence
Keywords: Barrett's esophagus; Esophageal cancer; Neoplastic stem cells; CD44; CD133; EpCAM;
CD44 deficiency enhanced Streptococcus equi ssp. zooepidemicus dissemination and inflammation response in a mouse model
Keywords: Streptococcus equi ssp. zooepidemicus; CD44; Inflammatory cytokine production; Bacterial dissemination;
Activation of Wnt signaling pathway by AF1q enriches stem-like population and enhance mammosphere formation of breast cells
Keywords: AF1q; Wnt; Stem; CD44; CD24;
A cancer/testis antigen, NY-SAR-35, induces EpCAM, CD44, and CD133, and activates ERK in HEK293 cells
Keywords: Cancer/testis antigen; NY-SAR-35; EpCAM; CD44; CD133; Pluripotency genes;
Expression of p63 and CD44 in oral squamous cell carcinoma and correlation with clinicopathological parameters
Keywords: Squamous cell carcinoma; Cancer stem cell; CD44; p63;
Hyaluronic acid modification of RNase A and its intracellular delivery using lipid-like nanoparticles
Keywords: Targeted protein delivery; Lipidoids; Protein engineering; CD44; Hyaluronic acid;
Original contributionPTEN loss and p27 loss differ among morphologic patterns of prostate cancer, including cribriform
Keywords: Gleason grading; Prostate cancer; PTEN; CDKN1B; p27; CD44;
The PBX1 lupus susceptibility gene regulates CD44 expression
Keywords: Lupus; PBX1; CD44; T cells;
Endogenous and exogenous miR-520c-3p modulates CD44-mediated extravillous trophoblast invasion
Keywords: Human placenta; Extravillous trophoblast; Cell invasion; MicroRNA; CD44; Exosome;
Original articlePrognostic value of putative cancer stem cell markers (CD24, CD44, CD133, and ALDH1) in human papillary thyroid carcinoma
Keywords: Thyroid neoplasms; CD24; CD44; CD133; ALDH1; Cancer stem cell;
Rheostatic CD44 isoform expression and its association with oxidative stress in human malignant mesothelioma
Keywords: Malignant mesothelioma; CD44; Glutathione; Nrf2; Oxidative stress;
Original ResearchMetformin targets gastric cancer stem cells
Keywords: Gastric carcinoma; CD44; Primary tumour; Xenograft; Self-renewal; Tumourspheres;
Original ArticleThe depletion of ATM inhibits colon cancer proliferation and migration via B56γ2-mediated Chk1/p53/CD44 cascades
Keywords: ATM; Colon cancer; B56γ2; CD44; Tumorigenic potential; ATM; Ataxia-telangiectasia mutated; PIKK; phosphatidylinositol-3 kinase related kinase; FAT; FRAP-ATM-TRRAP domain; FATC; FAT-C-terminal domain; DDR; DNA damage response; DSBs; double strand breaks;
CEACAM1 is associated with recurrence after hepatectomy for colorectal liver metastasis
Keywords: CEACAM1; Colorectal cancer; Liver metastasis; Cancer stem cell marker; CD44; ALDH activity;
Original ArticleStatin suppresses Hippo pathway-inactivated malignant mesothelioma cells and blocks the YAP/CD44 growth stimulatory axis
Keywords: Statin; CD44; Hippo pathway; YAP; Cancer stem cell; Malignant mesothelioma;
Hyaluronate synthase-2 overexpression alters estrogen dependence and induces histone deacetylase inhibitor-like effects on ER-driven genes in MCF7 breast tumor cells
Keywords: Hyaluronan; Hyaluronate synthase 2; Estrogen signaling; Histone deacetylases; Breast cancer; AP1; activating protein -1; CD44; cluster of differenciation 44; DMEM; Dulbelcoo's modified Eagle's Medium; E2; 17β-estradiol; ER; estrogen receptor; ERE; estrog
3D-spheroids: What can they tell us about pancreatic ductal adenocarcinoma cell phenotype?
Keywords: 3D-spheroids; Pancreatic ductal adenocarcinoma; Cytokeratins; Proteoglycans; CD44; MMP-7;
Collagen XIV and a related recombinant fragment protect human vascular smooth muscle cells from calcium-/phosphate-induced osteochondrocytic transdifferentiation
Keywords: ALP; alkaline phosphatase; ANKH; progressive ankyloses gene; αSMA; alpha smooth muscle actin; BSA; bovine serum albumin; Ca/P; pro-calcifying culture medium containing elevated concentrations of calcium and phosphate; CD44; cluster of differentiation 44;
CD44 is a key player in non-alcoholic steatohepatitis
Keywords: CD44; Liver; NAFLD; Steatosis; NASH; MCP1; Macrophages;
Original ArticleTransforming growth factor-β-induced plasticity causes a migratory stemness phenotype in hepatocellular carcinoma
Keywords: CD44; EMT; HCC; TGF-beta; Stem; CI; Cell Index; CK-18; cytokeratin-18; CSCs; cancer stem cells; EMT; epithelial-mesenchymal transition; FBS; fetal bovine serum; HCC; hepatocellular carcinoma; mRNA; messenger RNA; qRT-PCR; quantitative reverse-transcript
Full length articleChondroitin sulfate-functionalized polyamidoamine as a tumor-targeted carrier for miR-34a delivery
Keywords: Chondroitin sulfate; Polyamidoamine; CD44; miR-34a delivery; Gene therapy;
Full length articleRetro-inverso d-peptide-modified hyaluronic acid/bioreducible hyperbranched poly(amido amine)/pDNA core-shell ternary nanoparticles for the dual-targeted delivery of short hairpin RNA-encoding plasmids
Keywords: Self-assembly; Nanoparticles; Dual-targeting; Anxa1; CD44; Retro-inverso d-peptide;
Biomaterial-enabled delivery of SDF-1α at the ventral side of breast cancer cells reveals a crosstalk between cell receptors to promote the invasive phenotype
Keywords: Chemokines; SDF-1α/CXCL12; Breast cancer cells; Metastasis; Tumoral niche; Hyaluronan; Polyelectrolyte multilayer films; CXCR4; CD44;
Metabolic pathway of 4-pyridone-3-carboxamide-1β-d-ribonucleoside and its effects on cellular energetics
Keywords: A375; human malignant melanoma cells; ADA; adenosine deaminase; ADK; adenosine kinase; AMPD; AMP deaminase; CD 31; platelet endothelial cell adhesion molecule; CD44; CD44 antigen; CD 45; receptor type tyrosine-protein phosphatase; CD73; 5â²-nucleotidase;
EMT induced by EGF and wounding activates hyaluronan synthesis machinery and EV shedding in rat primary mesothelial cells
Keywords: BSA; bovine serum albumin; CD44; hyaluronan receptor, cluster of differentiation 44; DAB; 3,3â²-diaminobenzidine; GFP; green fluorescent protein; ECM; extracellular matrix; EM; electron microscope; EMT; epithelial to mesenchymal transition; EV; extracell
Roles and targeting of the HAS/hyaluronan/CD44 molecular system in cancer
Keywords: ADAM; a disintegrin and metalloproteinase; ADAMTS; a disintegrin and metalloproteinase with thrombospondin motifs; AMPK; adenosine monophosphate activated protein kinase; CD44; cluster of differentiation 44; CD44s; standard CD44; CD44v; CD44 variant isofo
A CD44-biosensor for evaluating metastatic potential of breast cancer cells based on quartz crystal microbalance
Keywords: CD44; Quartz crystal microbalance; Metastatic potential; Breast cancer cells; Stiffness;
CD44 enhances macrophage phagocytosis and plays a protective role in Streptococcus equi subsp. zooepidemicus infection
Keywords: CD44; Macrophages; Phagocytosis; Streptococcus equi subsp. zooepidemicus;
Trametinib plus 4-Methylumbelliferone Exhibits Antitumor Effects by ERK Blockade and CD44 Downregulation and Affects PD-1 and PD-L1 in Malignant Pleural Mesothelioma
Keywords: 4-Methylumbelliferone; CD44; ERK; Malignant pleural mesothelioma; Trametinib;
CD44Â + cancer cell-induced metastasis: A feasible neck metastasis model
Keywords: Neck metastasis; Animal model; Oral squamous cell carcinoma; Cancer stem cell; Xenograft; CD44;
Epigallocatechin-3-Gallate: The Prospective Targeting of Cancer Stem Cells and Preventing Metastasis of Chemically-Induced Mammary Cancer in Rats
Keywords: Epigallocatechin gallate; Mammary tumor; Cancer stem cells; Antioxidant; Ki-67; CD44;
Pathological α-synuclein exacerbates the progression of Parkinson's disease through microglial activation
Keywords: AKT; protein kinase B; AP-1; activator protein-1; BV-2; immortalized murine microglia cell line; CD11b; cluster of differentiation 11b; CD36; cluster of differentiation 36; CD44; cluster of differentiation 44; CD68; cluster of differentiation 68; CNS; cen
Human mesenchymal stem cells secrete hyaluronan-coated extracellular vesicles
Keywords: 4-MU; 4-methylumbelliferone; BSA; bovine serum albumin; CD44; hyaluronan receptor, cluster of differentiation 44; CLEM; correlative light and electron microscopy; GFP; green fluorescent protein; ECM; extracellular matrix; EM; electron microscope; EV; extr
The CD44 ligand hyaluronic acid is elevated in the cerebrospinal fluid of suicide attempters and is associated with increased blood-brain barrier permeability
Keywords: Suicide; CSF; Hyaluronic acid; CD44; MMP9; Inflammation;