Keywords: CDC، سمیت سلولی وابسته به مکمل; ADCC, antibody-de-pendent cytotoxicity; ALM, alemtuzumab; CLL, chronic lymphocytic leukemia; CCP, complement control protein; CDC, complement-dependent cytotoxicity; MAC, membrane attack complex; NIP, 5-iodo-4-hydroxy-3-nitrophenacetyl; OFA, ofatumumab; r
مقالات ISI CDC، سمیت سلولی وابسته به مکمل (ترجمه نشده)
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Keywords: CDC، سمیت سلولی وابسته به مکمل; ABMR, antibody-mediated rejection; CDC, complement-dependent cytotoxicity; CDCXM, complement-dependent cytotoxicity crossmatch; DSA, donor-specific antibodies; DTT, dithiothreitol; EDTA, ethylenediaminetetraacetic acid; FCXM, flow cytometry crossmatch; HL
Keywords: CDC، سمیت سلولی وابسته به مکمل; Crohn's disease; IBD; Inflammatory pathways; TNF inhibitors; Ulcerative colitisADA, Adalimumab; ADCC, Antibody-dependent cellular cytotoxicity; CD, Crohn's disease; CDC, Complement-dependent cytotoxicity; CZP, Certolizumab pegol; ETA, Etanercept; FcγR, Fc
Keywords: CDC، سمیت سلولی وابسته به مکمل; AMR, antibody mediated rejection; BAL, bronchoalveolar lavage; BOS, bronchiolitis obliterans syndrome; CDC, complement-dependent cytotoxicity; CF, cystic fibrosis; CLAD, chronic lung allograft dysfunction; CMV, cytomegalovirus; CT, computed tomography; DA
Different sensitivity of rituximab-treatment to B-cells between ABO-incompatible kidney and liver transplantation
Keywords: CDC، سمیت سلولی وابسته به مکمل; Ab, antibody; ABO-C, ABO-blood-type compatible; ABO-I, ABO-blood-type incompatible; ADCC, antibody-dependent cell-mediated cytotoxicity; AMR, antibody-mediated rejection; AR, acute rejection; BMI, body mass index; CDC, complement-dependent cytotoxicity; C
Epitope-specificities of HLA antibodies: The effect of epitope structure on Luminex technique-dependent antibody reactivity
Keywords: CDC، سمیت سلولی وابسته به مکمل; HLA, human leukocyte antigen; CDC, complement-dependent cytotoxicity; CDCXM, complement-dependent cytotoxicity crossmatch; MFI, median fluorescence intensity; PRA, panel reactive antibody; SA, single antigenEplet; HLA antibodies; Luminex; HLAMatchmaker; H
Single molecule Förster resonance energy transfer studies of the effect of EndoS deglycosylation on the structure of IgG
Keywords: CDC، سمیت سلولی وابسته به مکمل; Fab, fragment antigen binding; Fc, fragment crystallizable; IgG, immunoglobulin G; FcγR, Fcγ receptor; ADCC, antibody-dependent cell-mediated cytotoxicity; CDC, complement-dependent cytotoxicity; SAXS, small-angle X-ray scattering; FRET, Förster resonance
Evolution of serum and intra-graft donor-specific anti-HLA antibodies in a patient with two consecutive liver transplantations
Keywords: CDC، سمیت سلولی وابسته به مکمل; aAMR, acute antibody-mediated rejection; AMR, antibody-mediated rejection; B(+)ND1SA, non-donor 1 specific anti-HLA antibodies eluted from liver biopsy; CDC, complement-dependent cytotoxicity; CT, computed tomography; D, day; DSA, anti-HLA donor-specific
Early acute antibody-mediated rejection of a negative flow crossmatch 3rd kidney transplant with exclusive disparity at HLA-DP
Keywords: CDC، سمیت سلولی وابسته به مکمل; a.a., amino acid; Abs, antibodies; AMR, antibody-mediated rejection; cPRA, calculated panel reactive antibody; C’, complement; CDC, complement-dependent cytotoxicity; DSA, donor-specific alloantibodies; FXM, flow cross-match; IgG MFI, IgG mean fluorescenc
The effect of sugar removal on the structure of the Fc region of an IgG antibody as observed with single molecule Förster Resonance Energy Transfer
Keywords: CDC، سمیت سلولی وابسته به مکمل; IgG, immunoglobulin G; FRET, Förster Resonance Energy Transfer; Fab, fragment antigen binding; Fc, fragment crystallizable; ADCC, antibody-dependent cell-mediated cytotoxicity; CDC, complement-dependent cytotoxicity; SAXS, small-angle X-ray scattering; Fc
Acute myeloid leukemia and novel biological treatments: Monoclonal antibodies and cell-based gene-modified immune effectors
Keywords: CDC، سمیت سلولی وابسته به مکمل; AML, acute myeloid leukemia; LSC, leukemic stem cell; mAb, monoclonal antibody; ADCC, antibody-dependent cell-mediated cytotoxicity; CDC, complement-dependent cytotoxicity; GO, Gentuzumab Ozogamicin; OS, overall survival; EFS, event-free survival; BiTE, b
Modified solid-phase alloantibody detection for improved crossmatch prediction
Keywords: CDC، سمیت سلولی وابسته به مکمل; AMR, antibody-mediated rejection; AUC, area under the curve; CDC, complement-dependent cytotoxicity; CDCXM, complement-dependent cytotoxicity crossmatch; DSA, donor-specific antibodies; DTT, dithiotreitol; IQR, interquartile range; MFI, mean fluorescence
Analytical characterization of biosimilar antibodies and Fc-fusion proteins
Keywords: CDC، سمیت سلولی وابسته به مکمل; ADCC, Antibody-dependent cell-mediated cytotoxicity; Ala, Alanine; Asn, Asparagine; CDC, Complement-dependent cytotoxicity; CDR, Complementarity-determining region; CE, Capillary electrophoresis; CE-LIF, Capillary electrophoresis with laser-induced fluore
Diagnostic accuracy of solid phase HLA antibody assays for prediction of crossmatch strength
Keywords: CDC، سمیت سلولی وابسته به مکمل; AHG, anti-human globulin; AUC, area under the curve; CDC, complement-dependent cytotoxicity; CI, confidence interval; DSA, donor-specific antibody; FC, flow cytometric; MCS, median channel shift; MFI, mean fluorescence intensity; ROC, receiver operating c
HBXIP upregulates CD46, CD55 and CD59 through ERK1/2/NF-κB signaling to protect breast cancer cells from complement attack
Keywords: CDC، سمیت سلولی وابسته به مکمل; HBXIP, hepatitis B X-interacting protein; mCRPs, membrane-bound complement regulatory proteins; CDC, complement-dependent cytotoxicity; NF-κB, nuclear factor κB; IκB, inhibitor κB; ERK, extracellular regulatory kinase; JNK, c-Jun N-terminal kinaseHBXIP; m
Enhanced antibody-dependent cellular phagocytosis by chimeric monoclonal antibodies with tandemly repeated Fc domains
Keywords: CDC، سمیت سلولی وابسته به مکمل; Ab, antibody; ADCC, antibody-dependent cellular cytotoxicity; ADCP, antibody-dependent cellular phagocytosis; CDC, complement-dependent cytotoxicity; (G4S)3 linker, a -Gly-Gly-Gly-Gly-Ser- triple tandem repeat; IVIG, intravenous Ig; mAb, monoclonal antibo
CD4 ligation excludes the Carma1–Bcl10–MALT1 complex from GM1-positive membrane rafts in CD3/CD28 activated T cells
Keywords: CDC، سمیت سلولی وابسته به مکمل; ADCC, antibody-dependent cell-mediated cytotoxicity; APC, antigen-presenting-cells; Bcl10, B cell lymphoma 10; Carma1, caspase-recruitment domain-membrane-associated guanylate kinase protein1; CDC, complement-dependent cytotoxicity; EGFP, enhance green fl
Generation of a panel of monoclonal antibodies against atypical chemokine receptor CCX-CKR by DNA immunization
Keywords: CDC، سمیت سلولی وابسته به مکمل; CDC, Complement-dependent cytotoxicity; CTM, Cytotoxicity medium; DARC, Duffy antigen receptor for chemokine; E. coli, Escherichia coli; FBS, Fetal bovine serum; FCM, Flow cytometry; FITC, Fluorescein isothiocyanate; IF, Immunofluorescence; IP, Immunoprec
Nonfucosylated anti-CD20 antibody potentially induces apoptosis in lymphoma cells through enhanced interaction with FcγRIIIb on neutrophils
Keywords: CDC، سمیت سلولی وابسته به مکمل; ADCC, antibody-dependent cellular cytotoxicity; CDC, complement-dependent cytotoxicity; NK cell, natural killer cell; G-CSF, granulocyte colony-stimulating factor; PBMC, peripheral blood mononuclear cell; LPS, lipopolysaccharide; PMA, phorbol myristate ac
High throughput screening for antibody induced complement-dependent cytotoxicity in early antibody discovery using homogeneous macroconfocal fluorescence imaging
Keywords: CDC، سمیت سلولی وابسته به مکمل; CDC, Complement-dependent cytotoxicity; FACS, Fluorescent Activated Cell Sorter; FMAT, fluorometric microvolume assay technology; NHS, Normal Human Serum; IgG, Immunoglobulin G; HuIgG, Human IgG; HMFI, homogeneous macroconfocal fluorescence imagingComplem
Development and optimization of a cell-based neutralizing antibody assay using a sample pre-treatment step to eliminate serum interference
Keywords: CDC، سمیت سلولی وابسته به مکمل; IgT, therapeutic monoclonal antibody; CDC, complement-dependent cytotoxicity; mAb, monoclonal antibody; pAb, polyclonal antibody; ATA, anti-therapeutic antibody; NAb, neutralizing antibody; RF, rheumatoid factor; CIC, complement immune complex; NHS, norma
Comparisons of affinities, avidities, and complement activation of adalimumab, infliximab, and etanercept in binding to soluble and membrane tumor necrosis factor
Keywords: CDC، سمیت سلولی وابسته به مکمل; TNF-R, TNF receptor; RA, rheumatoid arthritis; mTNF, membrane TNF; CDC, complement-dependent cytotoxicity; TACE, TNF-alpha-converting enzyme; RU, response units; Kon, association rate constant; Koff, dissociation rate constant; BSA, bovine serum albumin;
Quantitative proteomic analysis of follicular lymphoma cells in response to rituximab
Keywords: CDC، سمیت سلولی وابسته به مکمل; ADCC, antibody-dependent cellular cytotoxicity; amu, atomic mass units; B-NHL, B-cell non-Hodgkin's lymphoma; CDC, complement-dependent cytotoxicity; ICAT, isotope-coded affinity tag; LC, liquid chromatography; MS/MS, tandem mass spectrometry; SCX, strong
A role for autoantibodies in enhancement of pro-inflammatory cytokine responses to a self-antigen, thyroid peroxidase
Keywords: CDC، سمیت سلولی وابسته به مکمل; Ab, antibody; ADCC, antibody-dependent cellular cytotoxicity; AITD, autoimmune thyroid disease; APC, antigen-presenting cell; CDC, complement-dependent cytotoxicity; FcR, Fcγ-receptor; GD, Graves' disease; FCS, foetal calf serum; HT, Hashimoto's thyroidit
The GD2-specific 14G2a monoclonal antibody induces apoptosis and enhances cytotoxicity of chemotherapeutic drugs in IMR-32 human neuroblastoma cells
Keywords: CDC، سمیت سلولی وابسته به مکمل; ADCC, antibody-dependent cell-mediated cytotoxicity; CDC, complement-dependent cytotoxicity; dox, doxorubicin; ECM, extra cellular matrix; FAK, focal adhesion kinase; mAb, monoclonal antibody; NB, neuroblastoma; PI, propidium iodide; TPT, topotecan; VP-16
The Design and Characterization of Oligospecific Antibodies for Simultaneous Targeting of Multiple Disease Mediators
Keywords: CDC، سمیت سلولی وابسته به مکمل; scFv, single-chain Fv; DSC, differential scanning calorimetry; SEC-HPLC, size-exclusion HPLC; ADCC, antibody-dependent cellular cytotoxicity; HRP, horseradish peroxidase; CDC, complement-dependent cytotoxicity; E/T ratio, effector-to-target ratio; CDR, co
Crystal structure of chimeric antibody C2H7 Fab in complex with a CD20 peptide
Keywords: CDC، سمیت سلولی وابسته به مکمل; mAb, monoclonal antibody; CDC, complement-dependent cytotoxicity; ADCC, antibody-dependent cell cytotoxicity; CDRs, complementarity determining regionsC2H7; CD20; Epitope; Antibody structure
Mapping of binding epitopes of a human decay-accelerating factor monoclonal antibody capable of enhancing rituximab-mediated complement-dependent cytotoxicity
Keywords: CDC، سمیت سلولی وابسته به مکمل; mAb, monoclonal antibody; CDC, complement-dependent cytotoxicity; mCRPs, membrane complement regulatory proteins; DAF, decay-accelerating factor; SCR, short consensus repeat; NHS, normal human serumDecay-accelerating factor; Monoclonal antibody; Complemen
Anti-CD20 antibody suppresses anti-HLA antibody formation in a HLA-A2 transgenic mouse model of sensitization
Keywords: CDC، سمیت سلولی وابسته به مکمل; AMR, Antibody-mediated rejection; CDC, complement-dependent cytotoxicity; CI, cytotoxicity index; DSA, donor-specific antibodies; FlowPRA, flow cytometric PRA assay; PRA, panel reactive antibodies; PSG, primary skin graft; SSG, secondary skin graftAnti-CD
Therapeutic potential of a fully human monoclonal antibody against influenza A virus M2 protein
Keywords: CDC، سمیت سلولی وابسته به مکمل; M2, matrix protein 2; M2e, ectodomain of M2; MAb, monoclonal antibody; ADCC, antibody-dependent cell-mediated cytotoxicity; CDC, complement-dependent cytotoxicity; HA, hemagglutinin; NA, neuraminidaseInfluenza A; Matrix protein; Antibody; Virus infection;
Soluble CD30 in patients with antibody-mediated rejection of the kidney allograft
Keywords: CDC، سمیت سلولی وابسته به مکمل; CDC, complement-dependent cytotoxicity; DSA, donor-specific antibodies; FCXM, flow-cytometry crossmatch; HR, humoral rejection; PRA, panel reactive antibodies; sCD30, soluble CD30.Kidney transplantation; Soluble CD30; Antibody-mediated rejection; C4d
High concentrations of therapeutic IgG1 antibodies are needed to compensate for inhibition of antibody-dependent cellular cytotoxicity by excess endogenous immunoglobulin G
Keywords: CDC، سمیت سلولی وابسته به مکمل; ADCC, antibody-dependent cellular cytotoxicity; CDC, complement-dependent cytotoxicity; EGF, epidermal growth factor; Ep-CAM, epithelial cell adhesion molecule; FACS, fluorescence-activated cell sorting; FcγR, Fc gamma receptor; FITC, fluoresceine isothio