دانلود مقالات ISI درباره Cdk8 + ترجمه فارسی

پاتوژنز مولکولی و سلولی تومورهای هیپوفیز

Molecular and cellular pathogenesis of pituitary tumors

Keywords: Sporadic/hereditary pituitary tumors; Whole genome/exome sequencing; USP8 mutation; Pituitary adenoma progression; Pituitary carcinoma; Pituitary tumor senescence; AIP; aryl hydrocarbon-interacting protein; BC; bromocriptine; bFGF; basic fibroblast growth

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

تنظیم پروموتور دیررس نوع 16 پاپیلومای انسانی با طول عمر رونویسی

Regulation of the human papillomavirus type 16 late promoter by transcriptional elongation

Keywords: Papillomavirus; Gene expression; Late promoter; CDK9; CDK8; P-TEFb; Mediator; Pol II carboxy terminal domain; Brd4; Differentiation; Transcriptional elongation;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

MicroRNA-26a is a key regulon that inhibits progression and metastasis of c-Myc/EZH2 double high advanced hepatocellular carcinoma

Keywords: c-Myc/EZH2 double positive; microRNA-26a; Epigenetics modification; Metastasis; Advanced hepatocellular carcinoma; AAV; adeno-associated virus; CDK8; cyclin dependent kinase 8; CTDSP2; CTD small phosphatase 2; DEN; diethylnitrosamine; DZNep; 3-deazaneplan

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2018 سفارش ترجمه

CDK8 regulates the angiogenesis of pancreatic cancer cells in part via the CDK8-β-catenin-KLF2 signal axis

Keywords: CDK8; Angiogenesis; β-catenin; KLF2; Pancreatic cancer;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

Mediator, known as a coactivator, can act in transcription initiation in an activator-independent manner in vivo

Keywords: Transcriptional coactivator; General transcription factor; MED14; MED17; CDK8;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

Discovery of potent and selective CDK8 inhibitors through FBDD approach

Keywords: CDK8; Inhibitor; Fragment-based drug discovery (FBDD);

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Design and synthesis of selective CDK8/19 dual inhibitors: Discovery of 4,5-dihydrothieno[3′,4′:3,4]benzo[1,2-d]isothiazole derivatives

Keywords: CDK8; CDK19; Cyclin-dependent kinases (CDKs); Transcriptional regulation; STAT1; RPMI8226; SW480; DMG; 4,5-Dihydrothieno[3′,4′:3,4]benzo[1,2-d]isothiazole;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Studies of CDK 8/19 inhibitors: Discovery of novel and selective CDK8/19 dual inhibitors and elimination of their CYP3A4 time-dependent inhibition potential

Keywords: ADME; absorption, distribution, metabolism, and excretion; AML; acute myelogenous leukemia; AUC; area under the blood concentration time curve; b.i.d.; twice a day; CDK; Cyclin-dependent kinase; CLtotal; clearance; Cmax; maximum drug concentration; CRC; c

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه

Mediator Kinase Phosphorylation of STAT1 S727 Promotes Growth of Neoplasms With JAK-STAT Activation

Keywords: STAT1; MPN; CDK8; Kinase inhibitor; Leukemia; Super-enhancer; Cortistatin A; Ruxolitinib;

دانلود رایگان متن کامل مقاله ISI 49 صفحه سال انتشار : 2017 سفارش ترجمه

H19 Noncoding RNA, an Independent Prognostic Factor, Regulates Essential Rb-E2F and CDK8-β-Catenin Signaling in Colorectal Cancer

Keywords: H19; RB1; E2F; CDK8; β-Catenin; Colorectal cancer;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Mutated K-ras activates CDK8 to stimulate the epithelial-to-mesenchymal transition in pancreatic cancer in part via the Wnt/β-catenin signaling pathway

Keywords: CDK8; Pancreatic cancer; K-ras mutation; Wnt/β-catenin; EMT;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

The two faces of Cdk8, a positive/negative regulator of transcription

Keywords: Cdk8; Transcription regulation;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

New insights into Notch1 regulation of the PI3K-AKT-mTOR1 signaling axis: Targeted therapy of γ-secretase inhibitor resistant T-cell acute lymphoblastic leukemia

Keywords: ADAM; a disintegrin and metalloprotease; AICAR; 5-aminoimidazole-4-carboxamide ribonucleotide; AKT; protein kinase B (PKB); ALL; acute lymphoblastic leukemia; AML; acute myeloid leukemia; AMPK; adenosine monophosphate (AMP) activated protein kinase; ANK;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Wogonin induced G1 cell cycle arrest by regulating Wnt/β-catenin signaling pathway and inactivating CDK8 in human colorectal cancer carcinoma cells

Keywords: Wogonin; G1 arrest; β-catenin; CDK8; Colorectal cancerTCF, T-cell factor; LRP, low-density lipoprotein receptor-related protein; GSK3β, glycogen synthase kinase 3β; Lef, lymphoid enhancer factor; CDK, cyclin-dependent kinases; Dvl, disheveled; AXIN, axis

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

The C. elegans CDK8 Mediator module regulates axon guidance decisions in the ventral nerve cord and during dorsal axon navigation

Keywords: Neuronal development; Axon guidance; Transcription; Mediator; CDK8; SAX-3; ROBO; C. elegans

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

The retroviral cyclin of walleye dermal sarcoma virus binds cyclin-dependent kinases 3 and 8

Keywords: WDSV; Retroviral cyclin; rv-cyclin; Cyclin C; cdk8; cdk3; Mediator; Retinoblastoma protein; Rb; Cell cycle

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Dysregulation of CDK8 and Cyclin C in tumorigenesis

Keywords: Mediator complex; CDK8; Transcription; Tumorigenesis; MD simulation

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2011 سفارش ترجمه

Prenatal exposure to the acetylcholinesterase inhibitor methanesulfonyl fluoride alters forebrain morphology and gene expression

Keywords: Development and regeneration; Neurotrophic factors: biological effects; ACh; acetylcholine; AChE; acetylcholinesterase; ChAT; choline acetyltransferase; CNS; central nervous system; CDK8; cyclin-dependent kinase 8; CGI 110; comparative gene identification

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

An activation domain within the walleye dermal sarcoma virus retroviral cyclin protein is essential for inhibition of the viral promoter

Keywords: WDSV; rv-cyclin; cdk8; Cyclin C; Sur2; TBP; VP16; Mediator;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه