Keywords: Human carboxylesterases; CES1; CES2; Substrate preference; Inhibitor spectra; Inducer;
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Keywords: AADAC; arylacetamide deacetylase; AChE; acetylcholinesterase; AEA; arachidonoylethanolamide; 2-AG; 2-arachidonoylglycerol; BChE; butyrylcholinesterase; BBB; blood-brain barrier; CES1; carboxylesterases 1; CES2; carboxylesterases 2; CNS; central nervous sy
Presence and inter-individual variability of carboxylesterases (CES1 and CES2) in human lung
Keywords: 4-Nitrophenyl acetate (PubChem CID: 13243); 4-Nitrophenol (PubChem CID: 980); Fluorescein diacetate (PubChem CID: 16850); 4-methylumbelliferone (PubChem CID: 5280567); Fast Blue RR salt (PubChem CID: 2724074); Bis-4-nitrophenyl phosphate (PubChem CID: 255
In vitro approach to elucidate the relevance of carboxylesterase 2 and N-acetyltransferase 2 to flupirtine-induced liver injury
Keywords: AADAC; arylacetamide deacetylase; AcetylCoA; acetyl coenzyme A; Ad; adenovirus; BNPP; bis-(p-nitrophenyl) phosphate; BSO; l-buthionine sulfoximine; CES; carboxylesterase; DFP; diisopropyl phosphorofluoride; DMSO; dimethyl sulfoxide; Eserine; sulfate physo
Single-nucleotide polymorphisms in the genes of CES2, CDA and enzymatic activity of CDA for prediction of the efficacy of capecitabine-containing chemotherapy in patients with metastatic breast cancer
Keywords: 5â²DFCR; 5â²deoxy-5-fluorocytidine; 5â²DFUR; 5â²-deoxy-5-fluorouridine; 5-FU; 5-fluorouracil; AEs; adverse events; AML; acute promyelocytic leukemia; AU; arbitrary unit; CDA; cytidine deaminase; CES; carboxylesterase; DPD; dihydropyrimidine dehydrogen
Ontogenic expression of human carboxylesterase-2 and cytochrome P450 3A4 in liver and duodenum: Postnatal surge and organ-dependent regulation
Keywords: CES2; carboxylesterase-2; CYP3A4; cytochrome P450 3A4; GAPDH; glyceradehyde-3-phosphate dehydrogenase; GI; gastrointestinal; PBS; phosphate buffered saline; PPARα; peroxisome proliferator-activated receptor-α; RT-qPCR; reverse transcription-quantitative
A proposed mechanism for the adverse effects of acebutolol: CES2 and CYP2C19-mediated metabolism and antinuclear antibody production
Keywords: AO; aldehyde oxidase; ANA; antinuclear antibody; AADAC; arylacetamide deacetylase; BNPP; bis(4-nitrophenyl)phosphate; CES; carboxylesterase; CYP; cytochrome P450; DTNB; 5,5â²-dithiobis(2-nitrobenzoic acid); EDTA; ethylenediamine-N,N,Nâ²Nâ²-tetraacetic
Regulation and expression of aberrant methylation on irinotecan metabolic genes CES2, UGT1A1 and GUSB in the in-vitro cultured colorectal cancer cells
Keywords: Colorectal cancer cell; Aberrant methylation; CES2; UGT1A1; GUSB; CPT-11; Gene expression
Catabolism of 4-hydroxy-2-trans-nonenal by THP1 monocytes/macrophages and inactivation of carboxylesterases by this lipid electrophile
Keywords: HNE; 4-hydroxy-2-trans-nonenal; CES1; carboxylesterase 1; CES2; carboxylesterase 2; oxLDLs; oxidized low-density lipoproteins; Carboxylesterases; 4-Hydroxynonenal; THP1 monocytes; THP1 macrophages;
Inhibition of carboxylesterase activity of THP1 monocytes/macrophages and recombinant human carboxylesterase 1 by oxysterols and fatty acids
Keywords: AA; arachidonic acid; ABCA1; ATP binding cassette transporter A1; ABCG1; ATP binding cassette transporter G1; apoA1; apolipoproteinA1; apoE; apolipoproteinE; BSA; bovine serum albumin; CE; carboxylesterase; CES1; carboxylesterase 1; CES2; carboxylesterase
Inhibition of carboxylesterase 1 is associated with cholesteryl ester retention in human THP-1 monocyte/macrophages
Keywords: ACAT-1; acyl CoA cholesterol acyltransferase; BSA; bovine serum albumin; CEH; cholesteryl ester hydrolase; CES1; carboxylesterase 1; CES2; carboxylesterase 2; CPO; chlorpyrifos oxon; CVD; cardiovascular disease; EDTA; ethylenediamine tetraacetetic acid; F