Keywords: CGD، بیماری مزمن گرانولوماتوز; ASC, apoptosis-associated speck-like protein containing a caspase recruitment domain; CGD, chronic granulomatous disease; DAMP, damage-associated molecular pattern; Drp1, dynamin-related protein 1; DUSP16/MKP-7, dual specificity protein phosphatase 16/mit
مقالات ISI CGD، بیماری مزمن گرانولوماتوز (ترجمه نشده)
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Keywords: CGD، بیماری مزمن گرانولوماتوز; Inflammatory Bowel Disease; Very Early Onset Inflammatory Bowel Disease; Whole Exome Sequencing; Mucosal ImmunologyADAM17, A disintegrin and metalloproteinase domain 17; CGD, chronic granulomatous disease; COL7A1, collagen, type VII, α1; CVID, common vari
The NOX2-mediated ROS producing capacity of recipient cells is associated with reduced T cell infiltrate in an experimental model of chronic renal allograft inflammation
Keywords: CGD، بیماری مزمن گرانولوماتوز; CGD, Chronic granulomatous disease; DA, Dark Agouti; DHE, Dihydroethidium; Lew, Lewis; Mph, Macrophage; NOX2, NADPH oxidase 2; ROS, Reactive oxygen species; Tx, Transplantation; Tregs, Regulatory T cellsMacrophage; ROS; T cell; Transplantation
High glucose modulates IL-6 mediated immune homeostasis through impeding neutrophil extracellular trap formation
Keywords: CGD، بیماری مزمن گرانولوماتوز; 2-DG, 2-deoxy-d-glucose; CGD, Chronic Granulomatous disease; IL-6, interleukin-6; LPS, lipopolysaccharide; NETs, neutrophil extracellular traps; l-NAME, NG-nitro-l-arginine methyl ester; NCM, neutrophil culture medium; NADPH, nicotinamide adenine dinucleo
Quinone compounds regulate the level of ROS production by the NADPH oxidase Nox4
Keywords: CGD، بیماری مزمن گرانولوماتوز; AA-861, 2-(12-hydroxydodeca-5,10-diynyl)-3,5,6-trimethyl-p-benzoquinone; BQ, benzoquinone; CGD, chronic granulomatous disease; CHX, cycloheximide; DPI, diphenyliodonium; Duroquinone, 2,3,5,6-tetramethyl-1,4-benzoquinone; HQ, hydroquinone; tMetBQ, 2,5-dime
Different unequal cross-over events between NCF1 and its pseudogenes in autosomal p47phox-deficient chronic granulomatous disease
Keywords: CGD، بیماری مزمن گرانولوماتوز; CGD, chronic granulomatous disease; CYBB, Cytochrome b beta; EDTA, ethylenediaminetetraacetic acid; MLPA, multiplex ligase-dependent probe amplification; NCF1, neutrophil cytosolic factor-1; p47, protein of 47kD; phox, phagocyte oxidase; Ψ-NCF1, pseudo-NC
Teaching the basics of redox biology to medical and graduate students: Oxidants, antioxidants and disease mechanisms
Keywords: CGD، بیماری مزمن گرانولوماتوز; 4-HNE, hydroxynonenol; 8-OHdG, 8-hydroxy-2-deoxyguanosine; ATP, adenosine triphosphate; BH4, tetrahydrobiopterin; CAT, catalase; CGD, chronic granulomatous disease; cGMP, cyclic GMP; CKD, chronic kidney disease; CO2, carbon dioxide; CO3–, carbonate radica
Exaggerated inflammatory responses mediated by Burkholderia cenocepacia in human macrophages derived from Cystic fibrosis patients
Keywords: CGD، بیماری مزمن گرانولوماتوز; CF, Cystic fibrosis; CGD, Chronic granulomatous disease; IL-1β, Interleukin 1β; IL-10, Interleukin 10; IFN-γ, Interferon gamma; LDH, Lactate dehydrogenase; MCP-1, Monocyte chemotactic protein 1; MDM, Monocyte derived macrophageCystic fibrosis; Burkholderi
Consensus in silico computational modelling of the p22phox subunit of the NADPH oxidase
Keywords: CGD، بیماری مزمن گرانولوماتوز; Homology Modelling; p22phox; NADPH Oxidase3D, three-dimensional; a.a., amino acids; AMBER, assisted model building with energy refinement; CGD, chronic granulomatous disease; EBI, European Bioinformatics Institute; MOE, molecular operating environment; NA
Chronic granulomatous disease: Overview and hematopoietic stem cell transplantation
Keywords: CGD، بیماری مزمن گرانولوماتوز; Chronic granulomatous disease; infection; inflammation; autoimmune; allogeneic hematopoietic transplantationATG, Antithymocyte globulin; CGD, Chronic granulomatous disease; GvHD, Graft-versus-host disease; NADPH, Nicotinamide adenine dinucleotide phosphat
High levels of Crohn's disease-associated anti-microbial antibodies are present and independent of colitis in chronic granulomatous disease
Keywords: CGD، بیماری مزمن گرانولوماتوز; ABPA, allergic bronchopulmonary aspergillosis; ACCA, anti-chitobioside IgA; ALCA, anti-laminaribioside IgG; AMCA, anti-mannobioside IgG; ASCA, antibody to Saccharomyces cerevisiae; CD, Crohn's disease; CGD, Chronic granulomatous disease; EDID, ectodermal
Peptide-based inhibitors of the phagocyte NADPH oxidase
Keywords: CGD، بیماری مزمن گرانولوماتوز; DPI, diphenylene iodonium; CGD, chronic granulomatous disease; fMLF, formyl-methionyl-leucyl-phenylalanine; MPO, myeloperoxidase; phox, phagocyte oxidase; ROS, reactive oxygen speciesPhagocytes; NADPH oxidase; Inhibitors; gp91phox/NOX2; p22phox; p47phox
Amiloride derivatives modulate PS externalization in neutrophil-like PLB-985 cells
Keywords: CGD، بیماری مزمن گرانولوماتوز; APLT, aminophospholipid translocase; Carboxy-H2DCFDA-AM, carboxy-H2-dichloro-dihydrofluorescein-diacetate-diacetoxy methylester; CGD, chronic granulomatous disease; EIPA, 5-(N-ethyl-N-isopropyl)amiloride; ER, endoplasmic reticulum; FITC, fluorescein isoth
Transplantation immunology: Solid organ and bone marrow
Keywords: CGD، بیماری مزمن گرانولوماتوز; Bone marrow transplantation; solid-organ transplantation; graft rejection; graft-versus-host diseaseADA, Adenosine deaminase; ALG, Antilymphocyte globulin; APC, Antigen-presenting cell; ATG, Antithymocyte globulin; CGD, Chronic granulomatous disease; GVHD
Characterization of P-Rex1 for its role in fMet-Leu-Phe-induced superoxide production in reconstituted COSphox cells
Keywords: CGD، بیماری مزمن گرانولوماتوز; P-Rex1, phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1; fMLF, fMet-Leu-Phe; CGD, chronic granulomatous disease; FPR1, formyl peptide receptor 1; GEF, guanine nucleotides exchange factors; PIP3, phosphatidylinositol (3,4,5)-trisphosphat
Gene modulation and immunoregulatory roles of Interferonγ
Keywords: CGD، بیماری مزمن گرانولوماتوز; AP1, Activator Protein 1; APC, antigen presenting cells; CGD, chronic granulomatous disease; EAE, experimental autoimmune encephalomyelitis; ER, endoplasmic reticulum; GAS, Gamma Activation Sequence; GBP, guanylate-binding proteins; IDO, Indoleamine 2,3 d
Multiple endoscopic biopsies in research subjects: safety results from a National Institutes of Health series
Keywords: CGD، بیماری مزمن گرانولوماتوز; APS, autoimmune polyendocrine syndrome; CGD, chronic granulomatous disease; CVID, common variable immunodeficiency; HPS, Hermansky-Pudlak syndrome; NIH, National Institutes of Health; NSAID, nonsteroidal anti-inflammatory drug
The cytosolic subunit p67phox of the NADPH-oxidase complex does not bind NADPH
Keywords: CGD، بیماری مزمن گرانولوماتوز; CGD, chronic granulomatous disease; GST, glutathione-S-transferase; MF, neutrophil membrane fractionNADPH-oxidase; NADPH-binding; Tryptophan fluorescence; NADPH-dialdehyde; p67phox
Genetic deficiency of NADPH oxidase does not diminish, but rather enhances, LPS-induced acute inflammatory responses in vivo
Keywords: CGD، بیماری مزمن گرانولوماتوز; AP-1, activator protein-1; bw, body weight; CGD, chronic granulomatous disease; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; HBSS, Hanks’ balanced salt solution; ICAM-1, intercellular adhesion molecule-1; IL, interleukin; LPS, lipopolysaccharide; MCP-
Thapsigargin and flavin adenine dinucleotide ex vivo treatment rescues trafficking-defective gp91phox in chronic granulomatous disease leukocytes
Keywords: CGD، بیماری مزمن گرانولوماتوز; CGD, chronic granulomatous disease; EBV, Epstein–Barr virus; Endo-H, endoglycosidase H; ER, endoplasmic reticulum; FAD, flavin adenine dinucleotide; H338Y, amino acid change of His-338 to Tyr; THAPS, thapsigargin; NADPH oxidase, nicotinamide adenine dinuc
Regulation of cell proliferation by NADPH oxidase-mediated signaling: Potential roles in tissue repair, regenerative medicine and tissue engineering
Keywords: CGD، بیماری مزمن گرانولوماتوز; CGD, chronic granulomatous disease; DPI, diphenyleneiodonium; ERK, extracellular signal-regulated kinase; FAD, flavin adenine nucleotide; LMW-PTP, low-molecular weight-protein tyrosine phosphatase; Nox, NADPH oxidase catalytic subunit; PDGF, platelet-deri
Nox proteins in signal transduction
Keywords: CGD، بیماری مزمن گرانولوماتوز; Ang II, angiotensin II; CGD, chronic granulomatous disease; CLC-3, chloride channel 3; CNS, central nervous system; DPI, diphenylene iodonium; Duox, Dual oxidase; EGF, epidermal growth factor; elF4E, eukaryotic translation initiation factor 4E; eNOS, endo
Optical probes for detection and quantification of neutrophils’ oxidative burst. A review
Keywords: CGD، بیماری مزمن گرانولوماتوز; APF, 2-[6-(4′-amino)-phenoxy-3H-xanthen-3-on-9-yl] benzoic acid; CGD, chronic granulomatous disease; cNOS, nitric oxide synthase constitutive; DAF-FM, 4-amino-5-methylamino-2′,7′-difluorofluorescein; DAF-FM DA, 4-amino-5-methylamino-2′,7′-difluorofluoresc
Chronic granulomatous disease as a risk factor for autoimmune disease
Keywords: CGD، بیماری مزمن گرانولوماتوز; Chronic granulomatous disease; autoimmune; antiphospholipid syndrome; IgA nephropathy; lupus; juvenile idiopathic nephropathyANA, Antinuclear antibody; aPL, Antiphospholipid syndrome; CGD, Chronic granulomatous disease; CT, Computed tomography; JIA, Juven
Allogeneic hematopoietic cell transplantation for primary immune deficiency diseases: Current status and critical needs
Keywords: CGD، بیماری مزمن گرانولوماتوز; Allogeneic hematopoietic cell transplantation; primary immune deficiency; clinical trialADA, Adenosine deaminase; BMT, Bone marrow transplantation; CGD, Chronic granulomatous disease; CIBMTR, Center for International Blood and Marrow Transplant Research;
Hepatic Involvement and Portal Hypertension Predict Mortality in Chronic Granulomatous Disease
Keywords: CGD، بیماری مزمن گرانولوماتوز; ALP, alkaline phosphatase; CGD, chronic granulomatous disease; CI, confidence interval; HVPG, hepatic-venous pressure gradient; NRH, nodular regenerative hyperplasia; OR, odds ratio
ROS-deficient monocytes have aberrant gene expression that correlates with inflammatory disorders of chronic granulomatous disease
Keywords: CGD، بیماری مزمن گرانولوماتوز; AP-1, activator protein-1; CREB, cAMP response element-binding protein; CCL-, chemokine (C–C motif) ligand; CGD, chronic granulomatous disease; ERK-1/2, extracellular response kinase 1/2; GO, gene ontology; IFIT1, interferon-induced protein with tetratric
NADPH oxidases in lung biology and pathology: Host defense enzymes, and more
Keywords: CGD، بیماری مزمن گرانولوماتوز; ADAM, a disintegrin and metalloproteinase; BCR, B cell receptor; CGD, chronic granulomatous disease; ClC3, chloride channel 3; COPD, chronic obstructive pulmonary disease; DC, dendritic cell; DUOX, dual oxidase; DUOXA, DUOX maturation factor; EGF(R), epid
Insights into extensive deletions around the XK locus associated with McLeod phenotype and characterization of two novel cases
Keywords: CGD، بیماری مزمن گرانولوماتوز; MLS, McLeod syndrome; DMD, Duchenne muscular dystrophy; CYBB, chronic granulomatous disease; RPGR, retinitis pigmentosa; OTC, ornithine transcarbamylase deficiency; CGD, chronic granulomatous disease; XLRP, X-linked retinitis pigmentosa; dN/dS, synonymous
Opening the black box: Lessons from cell-free systems on the phagocyte NADPH-oxidase
Keywords: CGD، بیماری مزمن گرانولوماتوز; NADPH-oxidase; Phox; Cell-free system; Phagocytosis; Cytochrome b558AIR, autoinhibitory region; CGD, chronic granulomatous disease; GEF, Guanine nucleotide exchange factor; LiDS, lithium dodecyl sulfate; PA, phosphatidic acid; PAK, p21-activated kinase; P
Role of the small GTPase Rac in p22phox-dependent NADPH oxidases
Keywords: CGD، بیماری مزمن گرانولوماتوز; Rac; gp91phox; Nox1; Nox3; p67phoxROS, Reactive oxygen species; Nox, NADPH oxidase; CGD, chronic granulomatous disease; PMA, phorbol 12-myristate 13-acetate; TPR, tetratricopeptide repeat; Noxo1, Nox organizer 1; Noxa1, Nox activator 1
A splice-supporting intronic mutation in the last bp position of a cryptic exon within intron 6 of the CYBB gene induces its incorporation into the mRNA causing chronic granulomatous disease (CGD)
Keywords: CGD، بیماری مزمن گرانولوماتوز; BSA, bovine serum albumin; CAT scan, computerized axial tomography or CT scan; CGD, chronic granulomatous disease; CYBB, cytochrome b-245, beta polypeptide; ddH2O, double-distilled water; MIR, mammalian interspersed repeat; NADPH, nicotinamide adenine din
Hyperimmunoglobulin E syndrome: Two cases and a review of the literature
Keywords: CGD، بیماری مزمن گرانولوماتوز; ABPA, allergic bronchopulmonary aspergillosis; CGD, chronic granulomatous disease; HIES, hyperimmunoglobulin E syndrome; IFN, interferon; IgE, immunoglobulin E; IL, interleukin; IVIg, intravenous immunoglobulin; MRSA, methicillin-resistant Staphylococcus