Chiral-pool synthesis of 1,2,4-trisubstituted 1,4-diazepanes as novel Ï1 receptor ligands
Keywords: سنتز استخر کریال; 1,2,4-Trisubstituted 1,4-diazepanes; Chiral pool synthesis; Late stage diversification; Ï ligands; Ï1 agonists; Selectivity; Cholesterol biosynthesis; Sterol Î8/7-isomerase; Irwin test; Cognition enhancement;