دانلود مقالات ISI درباره CHO، تخمدان هامستر چینی + ترجمه فارسی

A Molecular Mechanism for Adrenergic-Induced Long QT Syndrome

Keywords: CHO، تخمدان هامستر چینی; heterologous expression; KCNQ1 mutation; long QT syndrome; protein kinase A stimulationcDNA, complementary deoxyribonucleic acid; CHO, Chinese hamster ovary; DNA, deoxyribonucleic acid; ECG, electrocardiogram; FK, forskolin; HEK293, human embryonic kidney

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

TRR469, a potent A1 adenosine receptor allosteric modulator, exhibits anti-nociceptive properties in acute and neuropathic pain models in mice

Keywords: CHO، تخمدان هامستر چینی; A1 adenosine receptors; Positive allosteric modulator; TRR469; Analgesia; Acute and chronic painAR, adenosine receptor; CCPA, 2-chloro N(6)-cyclopentyladenosine; CHO, chinese hamster ovary; CNS, central nervous system; CPA, N(6)-cyclopentyladenosine; DPCP

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Antiarrhythmic efficacy of CPUY102122, a multiple ion channel blocker, on rabbits with ischemia/reperfusion injury

Keywords: CHO، تخمدان هامستر چینی; CHO, Chinese Hamster Ovary; Cx43, connexin 43; CY22, CPUY102122; CK, creatine kinase; ECG, electrocardiograms; HE, hematoxylin and eosin stain; hERG, human Ether-à-go-go-Related Gene; IR, ischemia-reperfusion; LDH, lactate dehydrogenase; MDA, malondialdeh

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Recombinant human tripeptidyl peptidase-1 infusion to the monkey CNS: Safety, pharmacokinetics, and distribution

Keywords: CHO، تخمدان هامستر چینی; aCSF, artificial cerebrospinal fluid; AUC, area under the curve; CHO, Chinese hamster ovary; CLN2, ceroid lipofuscinosis neuronal type 2; Cmax, maximal concentration; CRIM, cross-reactive immunological material; D, deep tissue; ERT, enzyme replacement the

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Up-regulation of cholesterol associated genes as novel resistance mechanism in glioblastoma cells in response to archazolid B

Keywords: CHO، تخمدان هامستر چینی; ArchB, archazolid B; CHO, Chinese hamster ovary; Ct, cycle threshold; DMEM, Dulbecco's Modified Eagle Medium; DMSO, dimethyl sulfoxide; DPBS, Dulbecco's phosphate-buffered saline; FACS, fluorescence-activated cell sorting; FBS, fetal bovine serum; FC, fol

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

HCN4 Mutations in Multiple Families With Bradycardia and Left Ventricular Noncompaction Cardiomyopathy

Keywords: CHO، تخمدان هامستر چینی; exome sequencing; genetics; HCN4; ion channel; left ventricular noncompaction cardiomyopathy; sinus bradycardiacDNA, complementary deoxyribonucleic acid; CHO, Chinese hamster ovary; ECG, electrocardiogram; GoNL, Genome of the Netherlands; ICD, implantable

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Synthesis and evaluation of N6-substituted apioadenosines as potential adenosine A3 receptor modulators

Keywords: CHO، تخمدان هامستر چینی; AR, adenosine receptor; BAIB, bis-acetoxyiodobenzene; cAMP, adenosine 3′,5′-cyclic phosphate; CDI, carbonyldiimidazole; Cl-IB-MECA, 2-chloro-N6-(3-iodobenzyl)-5′-N-methylcarboxamidoadenosine; CHO, Chinese hamster ovary; DMF, N,N-dimethylformamide; DMEM, D

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Gene expression measurements normalized to cell number reveal large scale differences due to cell size changes, transcriptional amplification and transcriptional repression in CHO cells

Keywords: CHO، تخمدان هامستر چینی; CCI, cell cycle inhibitor; CHO, Chinese Hamster Ovary; ERCC, External RNA Controls Consortium; HC, heavy chain; IRES, Internal Ribosome Entry Site; LC, light chain; mTOR, mammalian target of rapamycin; mTORI, mTOR inhibitor; qP, specific productivity; qPC

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

A Fibrin-Specific Monoclonal Antibody from a Designed Phage Display Library Inhibits Clot Formation and Localizes to Tumors In Vivo

Keywords: CHO، تخمدان هامستر چینی; CDR, complementarity-determining region; SIP, small immune protein; CHO, Chinese hamster ovary; PEI, polyethyleneimine; RT, room temperaturefibrin; antibody phage display; tumor neovasculature; vascular targeting

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Induction of cholesterol biosynthesis by archazolid B in T24 bladder cancer cells

Keywords: CHO، تخمدان هامستر چینی; Archazolid B; Cholesterol biosynthesis; Fluvastatin; LDL uptake; SREBP; V-ATPase inhibition.ArchB, archazolid B; CHO, chinese hamster ovary; Ct, cycle threshold; DMEM, Dulbecco's Modified Eagle Medium; DMSO, dimethyl sulfoxide; DPBS, Dulbecco's phosphate-

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Overexpression of N-acetylglucosaminyltransferases III and V in human melanoma cells. Implications for MCAM N-glycosylation

Keywords: CHO، تخمدان هامستر چینی; Glycosyltransferases; N-glycosylation; Activity assay; Melanoma; MCAM; Transendothelial migrationAP, alkaline phosphatase; ATRA, all-trans-retinoic acid; CHO, Chinese hamster ovary; CML, chronic myelogenous leukemia; ESI-LTQ-FTICR, electrospray ionization

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Structural Characterization of Anti-Inflammatory Immunoglobulin G Fc Proteins

Keywords: CHO، تخمدان هامستر چینی; IgG, immunoglobulin G; IVIG, intravenous immunoglobulin G; PDB, Protein Data Bank; HEK, human embryonic kidney; CHO, Chinese hamster ovary; LC, liquid chromatography; ESI, electrospray ionization; MS, mass spectrometry; MM, molecular mass; PEG, polyethyle

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Modulation of in vivo IgG crystallization in the secretory pathway by heavy chain isotype class switching and N-linked glycosylation

Keywords: CHO، تخمدان هامستر چینی; BFA, Brefeldin A; CB, crystalline body; CDR, complementarity-determining region; CH1, heavy chain constant domain-1; CH2, heavy chain constant domain-2; CH3, heavy chain constant domain-3; CL, light chain constant domain; CHO, Chinese hamster ovary; DIC,

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Transport of glycosylphosphatidylinositol-anchored proteins from the endoplasmic reticulum

Keywords: CHO، تخمدان هامستر چینی; CHO, Chinese hamster ovary; ERES, endoplasmic reticulum exit site; EtNP, ethanolamine phosphate; GPI, glycosylphosphatidylinositol; GPI-AP, glycosylphosphatidylinositol-anchored protein; Man, mannoseCargo receptor; COPII coated vesicles; Endoplasmic retic

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

In vitro micronucleus assay for the analysis of total particulate matter in cigarette smoke: Comparison of flow cytometry and laser scanning cytometry with microscopy

Keywords: CHO، تخمدان هامستر چینی; TPM, Total particulate matter; CHO, Chinese hamster ovary; MN, Micronucleus frequencies; SYTOX, Green nucleic acid stain; EMA, Ethidium monoazide; FITC, Fluorescein 5(6)-isothiocyanate; PI, Propidium iodide; OECD, Organisation for Economic Co-operation an

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Tuning cell cycle of insect cells for enhanced protein production

Keywords: CHO، تخمدان هامستر چینی; cycE, cyclin E; RNAi, ribonucleic acid interference; GFP, green fluorescent protein; CAT, chloramphenicol acetyl transferase; CHO, Chinese hamster ovary; ds, double stranded; G1, gap-1; G2, gap-2; M, mitosis; MOI, multiplicity of infection; S, DNA synthes

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Discovery of a subtype selective inhibitor of the human betaine/GABA transporter 1 (BGT-1) with a non-competitive pharmacological profile

Keywords: CHO، تخمدان هامستر چینی; BGT-1, betaine/GABA transporter 1; BPDBA, N-(1-benzyl-4-piperidinyl)-2,4-dichlorobenzamide; CHO, Chinese hamster ovary; CNS, central nervous system; DMEM, Dulbecco's Modified Eagle Medium; DPBS, Dulbecco's Phosphate Buffered Saline; EF-1502, N-[4,4-bis(3-

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Characterization of two pathogenic mutations in cystathionine beta-synthase: Different intracellular locations for wild-type and mutant proteins

Keywords: CHO، تخمدان هامستر چینی; A, absorbance (1 cm); CBS, cystathionine β-synthase; cDNA, DNA complementary to RNA; CHO, Chinese hamster ovary; DAPI, 4′,6-diamidino-2-phenylindole; DSC, differential scanning calorimetry; ER, endoplasmic reticulum; GAPDH, glyceraldehyde 3-phosphate dehy

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Progress in the development of enzyme-based nerve agent bioscavengers

Keywords: CHO، تخمدان هامستر چینی; AChE, acetylcholinesterase; BChE, butyrylcholinesterase; CaE, carboxylesterase; CBDP, 2-(o-cresyl)-4H-1,3,2-benzodioxaphosphoran-2-one or cresyl saligenin phosphate; ChE, cholinesterase; CHO, Chinese hamster ovary; HDL, high density lipoprotein; OPNA, org

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Development of a Scale-Down Model of hydrodynamic stress to study the performance of an industrial CHO cell line under simulated production scale bioreactor conditions

Keywords: CHO، تخمدان هامستر چینی; ANOVA, analysis of variance; bG0, nongalactosylated glycan structure; bG1, monogalactosylated glycan structure; bG2, bigalactosylated glycan structure; HighM, high-mannose isoforms; CHO, Chinese Hamster Ovary; VCD, viable cell density [cells/mL]Scale-Down

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Cell-penetrating peptides: 20 years later, where do we stand?

Keywords: CHO، تخمدان هامستر چینی; CPP, cell-penetrating peptide; MALDI, matrix-assisted laser desorption; TOF, time of flight; MS, mass spectrometry; ON, oligonucleotide; EGFP, enhanced green fluorescent protein; CHO, Chinese hamster ovary; FITC, fluorescein isothiocyanate; CS, chondroiti

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Efficient recombinant protein production and secretion from nuclear transgenes in Chlamydomonas reinhardtii

Keywords: CHO، تخمدان هامستر چینی; ALG, asparagine linked glycosylation; CAH1, Chlamydomonas reinhardtii carbonic anhydrase 1; cCA, secretion signal of CAH1; CHO, Chinese hamster ovary; gLuc, Gaussia princeps luciferase; LpIBP, Lollium perenne ice binding protein; PTM, posttranslational mo

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Characterization by flow cytometry of fluorescent, selective agonist probes of the A3 adenosine receptor

Keywords: CHO، تخمدان هامستر چینی; cAMP, 3′,5′-cyclic adenosine monophosphate; CHO, Chinese hamster ovary; Cl-IB-MECA, 1-[2-chloro-6-[[(3-iodophenyl)methyl]amino]-9H-purin-9-yl]-1-deoxy-N-methyl-β-d-ribofuranuronamide; DMEM, Dulbecco's Modified Eagle Medium; DMSO, dimethyl sulfoxide; FBS,

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Development of a high-throughput electrophysiological assay for the human ether-à-go-go related potassium channel hERG

Keywords: CHO، تخمدان هامستر چینی; CHO, Chinese hamster ovary; cLogP, calculated logP, where P is the partition coefficient between n-octanol and water; Cm, membrane capacitance; HEK, human embryonic kidney; hERG, human ether-à-go-go related gene; IC50, 50% inhibitory concentration; IW, Io

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Synthesis and structure–activity relationships of 2-hydrazinyladenosine derivatives as A2A adenosine receptor ligands

Keywords: CHO، تخمدان هامستر چینی; AR, adenosine receptor(s); binodenoson, 2-((cyclohexylmethylene)hydrazino)adenosine; BSA, bovine serum albumin; CADO, 2-chloroadenosine; [3H]CCPA, [3H]2-chloro-N6-cyclopentyladenosine; CHO, Chinese hamster ovary; [3H]CGS21680, [3H]((2-(4-(2-carboxyethyl)p

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

β-Arrestin-biased signaling of PTH analogs of the type 1 parathyroid hormone receptor

Keywords: CHO، تخمدان هامستر چینی; CHO, Chinese hamster ovary; CRE, cAMP-responsive element; EFC, enzyme fragment complementation; ERK1/2, Extracellular signal-regulated kinase 1/2; GFP, Green fluorescent protein; GPCR, G protein-coupled receptor; HEK293, Human embryonic kidney 293; IP, In

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Mechanism of HERG potassium channel inhibition by tetra-n-octylammonium bromide and benzethonium chloride

Keywords: CHO، تخمدان هامستر چینی; CHO, Chinese hamster ovary; HERG, human ether-a-go-go related gene; IC50, concentrations of half-maximal inhibitory effects; κ, slope factor; QACs, quaternary ammonium compounds; V1/2, half-maximal activation (or inactivation) voltageQuaternary ammonium;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Parallel labeling experiments with [1,2-13C]glucose and [U-13C]glutamine provide new insights into CHO cell metabolism

Keywords: CHO، تخمدان هامستر چینی; ACL, ATP citrate lyase; AT, aminotransferase; CHO, Chinese hamster ovary; MFA, metabolic flux analysis; EMU, elementary metabolite unit; GC–MS, gas chromatography–mass spectrometry; GDH, glutamate dehydrogenase; IDH, isocitrate dehydrogenase; ME, malic en

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

Different matrix attachment regions flanking a transgene effectively enhance gene expression in stably transfected Chinese hamster ovary cells

Keywords: CHO، تخمدان هامستر چینی; CAT, chloramphenicol acetyltransferase; CHO, Chinese hamster ovary; ELISA, enzyme-linked immunosorbent assay; MARs, matrix attachment regions; RT-PCR, reverse transcription polymerase chain reaction; qPCR, Quantitative real-time PCRMatrix attachment regio

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

CB2: Therapeutic target-in-waiting

Keywords: CHO، تخمدان هامستر چینی; CHO, Chinese hamster ovary; CNS, central nervous system; ERK, extracellular-regulated kinase; GPCR, G protein-coupled receptor; GRK, G protein receptor kinase; HEK, human embryonic kidney; JNK, c-jun N terminal kinase; MAP kinase, mitogen-activated protei

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Crystal structure of a single-chain trimer of human adiponectin globular domain

Keywords: CHO، تخمدان هامستر چینی; ACRP30, adipocyte complement-related protein of 30 kDa; AMPK, 5′-AMP-activated protein kinase; CHO, Chinese hamster ovary; PEG, polyethylene glycol; ob/ob, obese mouseX-ray crystal structure; Adiponectin; Single-chain globular domain; Calcium binding

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Molecular basis of type I antithrombin deficiency in two women with recurrent venous thromboembolism in the first trimester of pregnancy

Keywords: CHO، تخمدان هامستر چینی; AT, antithrombin; VTE, venous thromboembolism; WT, wild-type; HEK293T, Human embryonic kidney 293T; CHO, Chinese hamster ovary; ER, endoplasmic reticulumAntithrombin; Gene mutation; Pregnancy; Venous thromboembolism

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Species-specific differences in the processing of acid α-glucosidase are due to the amino acid identity at position 201

Keywords: CHO، تخمدان هامستر چینی; GAA, acid α-glucosidase; rhGAA, recombinant human acid α-glucosidase; CHO, Chinese hamster ovary; MSX, methionine sulfoximine; ERT, enzyme replacement therapyAcid α-glucosidase; Glycogen storage disease type II; Pompe disease; Lysosome processing

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Peroxisome biogenesis disorders: Molecular basis for impaired peroxisomal membrane assembly : In metabolic functions and biogenesis of peroxisomes in health and disease

Keywords: CHO، تخمدان هامستر چینی; CG, complementation group; CHO, Chinese hamster ovary; ER, endoplasmic reticulum; PBD, peroxisome biogenesis disorder; PMP, peroxisomal membrane protein; PTS, peroxisomal targeting signalPeroxisome biogenesis disorder; Membrane biogenesis; Peroxin; CHO ce

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Persistently bound Ku at DNA ends attenuates DNA end resection and homologous recombination

Keywords: CHO، تخمدان هامستر چینی; DSBs, DNA double strand breaks; NHEJ, non-homologous end joining; HR, homologous recombination; MRX/N, Mre11-Rad50-Xrs2/Nbs1; Mt-Ku, Ku homolog from Mycobacterium tuberculosis; CHO, Chinese hamster ovary; Ku DKO, Ku70/80 double knock-out mouse embryonic f

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Transient receptor potential ankyrin 1 activation enhances hapten sensitization in a T-helper type 2-driven fluorescein isothiocyanate-induced contact hypersensitivity mouse model

Keywords: CHO، تخمدان هامستر چینی; AITC, allyl isothiocyanate; CHO, Chinese hamster ovary; CHS, contact hypersensitivity; CGRP, calcitonin gene-related peptide; CNA, cinnamaldehyde; DBP, dibutyl phthalate; DC, dendritic cell; FITC, fluorescein isothiocyanate; TRPA1, transient receptor pote

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Mephedrone, a new designer drug of abuse, produces acute hemodynamic effects in the rat

Keywords: CHO، تخمدان هامستر چینی; CHO, Chinese hamster ovary; HERG, human ether-a-go-go-related gene; ANOVA, analysis of variance; ECG, electrocardiogram; LVIDD, left ventricular internal diameter in diastole; LVIDS, left ventricular internal diameter in systole; LVVD, left ventricular vo

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

A novel dihydro-pyrazolo(3,4d)(1,2,4)triazolo(1,5a)pyrimidin-4-one (AJ23) is an antagonist at adenosine A1 receptors and enhances consolidation of step-down avoidance

Keywords: CHO، تخمدان هامستر چینی; AJ23, 7-methyl-1-phenyl-1,8-dihydropyrazolo-(3,4d)(1,2,4)triazolo(1,5a)pyrimidin-4-one; ACSF, artificial cerebrospinal fluid; CHO, Chinese Hamster Ovary; DMSO, d6 – dimethylsulphoxide; DPCPX, 1,3-dipropyl-8-cyclopentylxanthine; HEK, Human Embryonic Kidney

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

R222Q SCN5A Mutation Is Associated With Reversible Ventricular Ectopy and Dilated Cardiomyopathy

Keywords: CHO، تخمدان هامستر چینی; familial dilated cardiomyopathy; SCN5A mutations; ventricular ectopyAF, atrial fibrillation; CD, conduction system abnormalities; CHO, Chinese hamster ovary; DCM, dilated cardiomyopathy; ECG, electrocardiogram; EPS, electrophysiology studies; ICD, implant

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Is there still a future for neurokinin 3 receptor antagonists as potential drugs for the treatment of psychiatric diseases?

Keywords: CHO، تخمدان هامستر چینی; 5-HT, serotonin; BPRS, Brief Psychiatric Rating Scale; cAMP, cyclic adenosine monophosphate; CGI, Clinical Global Impressions; CHO, Chinese hamster ovary; CNS, central nervous system; DA, dopamine; DOPAC, 3,4-dihydroxyphenylacetic acid; GABA, γ-aminobutyr

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Congenital disorder of glycosylation type Ij (CDG-Ij, DPAGT1-CDG): Extending the clinical and molecular spectrum of a rare disease

Keywords: CHO، تخمدان هامستر چینی; CDG, congenital disorder of glycosylation; DPAGT1, UDP-GlcNAc: Dolichol Phosphate N-Acetylglucosamine-1-Phosphotransferase; ER, endoplasmatic reticulum; CHO, chinese hamster ovary; IEF, isoelectric focusing; SDS-PAGE, sodium dodecyl sulphate-polyacrylamid

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Blinatumomab: A historical perspective

Keywords: CHO، تخمدان هامستر چینی; AE, Adverse event; ALL, Acute lymphoblastic leukemia; BiTE®, Bispecific T cell Engager; CHO, Chinese hamster ovary; CLL, Chronic lymphocytic leukemia; CNS, Central nervous system; CR, Complete remission; DLBCL, Diffuse large B cell lymphoma; FL, Follicula

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Carvedilol blocks the cloned cardiac Kv1.5 channels in a β-adrenergic receptor-independent manner

Keywords: CHO، تخمدان هامستر چینی; Kv, voltage-gated K+ channel; CHO, Chinese hamster ovary; HERG, human ether-a-go-go related geneKv1.5; Carvedilol; Antiarrhythmic drug; Open channel block; Use-dependent block

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Minor structural modifications to alchemix influence mechanism of action and pharmacological activity

Keywords: CHO، تخمدان هامستر چینی; CHO, Chinese hamster ovary; CT DNA, calf thymus DNA; DMSO, dimethyl sulphoxide; DSB, double strand break; H2AX, histone-2AX; MDR, multidrug resistance; MTT, (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; TdT, terminal deoxynucleotidyl tran

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Epistatic Effects of Potassium Channel Variation on Cardiac Repolarization and Atrial Fibrillation Risk

Keywords: CHO، تخمدان هامستر چینی; atrial cell modeling; familial atrial fibrillation; genetics; potassium channelsAF, atrial fibrillation; AP, action potential; APD, action potential duration; CHO, Chinese hamster ovary; DNA, deoxyribonucleic acid; MAF, minor allele frequency; WT, wild-ty

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Design and characterization of novel cell-penetrating peptides from pituitary adenylate cyclase-activating polypeptide

Keywords: CHO، تخمدان هامستر چینی; CD, circular dichroism; CHO, Chinese hamster ovary; CPP, cell-penetrating peptide; FITC, fluorescein isothiocyanate; GFP, green-fluorescent protein; hCT, human calcitonin; HEK293, human embryonic kidney 293; MALDI-TOF MS, matrix-assisted laser desorption/

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Novel fluorescent antagonist as a molecular probe in A3 adenosine receptor binding assays using flow cytometry

Keywords: CHO، تخمدان هامستر چینی; AF488, Alexa Fluor-488; CHO, Chinese hamster ovary; CGS15943, N-[9-chloro-2-(2-furanyl)[1,2,4]triazolo[1,5-c]quinazolin-5-amine; CGS21680, 2-[p-(2-carboxyethyl)phenylethylamino]-5′-N-ethylcarboxamido-adenosine; Cl-IB-MECA, 1-[2-chloro-6-[[(3-iodophenyl)me

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Metabolic engineering of Chinese hamster ovary cells: Towards a bioengineered heparin

Keywords: CHO، تخمدان هامستر چینی; GAG, glycosaminoglycan; IdoA, l-iduronic acid; GlcA, d-glucuronic acid; GlcNAc, N-acetyl-d-glucosamine; CHO, Chinese hamster ovary; HS, heparan sulfate; ATIII, antithrombin III; Ext, exostosin; Ndst, N-deacetylase/N-sulfotransferase; Hs6st, heparan sulfat

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

N-glycosylation of the mammalian dipeptidyl aminopeptidase-like protein 10 (DPP10) regulates trafficking and interaction with Kv4 channels

Keywords: CHO، تخمدان هامستر چینی; CHO, Chinese hamster ovary; co-IP, co-immunoprecipitation; DMEM, Dulbecco's modified Eagle's medium; DPPL, dipeptidyl aminopeptidase-like protein; DPP6, dipeptidyl aminopeptidase-like protein 6; DPP10, dipeptidyl aminopeptidase-like protein 10; FACS, fluo

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Functional characteristics of the novel, human-derived recombinant FVIII protein product, human-cl rhFVIII

Keywords: CHO، تخمدان هامستر چینی; APTT, activated partial thromboplastin time; ANOVA, analysis of variance; APC, activated Protein C; BDD, B-domain deleted; BHK, baby hamster kidney; BSA, bovine serum albumin; CHO, Chinese hamster ovary; ETP, endogenous thrombin potential; FVIII(a), (acti

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه