دانلود مقالات ISI درباره برای + ترجمه فارسی

Investigating the metabolic alterations in a depressive-like rat model of chronic forced swim stress: An in vivo proton magnetic resonance spectroscopy study at 7T

Keywords: برای; In vivo proton magnetic resonance spectroscopy (1H MRS); Major depressive disorders; Chronic forced swim stress; MDD; major depressive disorder; 1H MRS; proton magnetic resonance spectroscopy; Cho; choline-compounds; mIns; myo-inositol; Cr; creatine; Glu

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Value of 18F-FET PET in adult brainstem glioma

Keywords: برای; ADC; apparent diffusion coefficient; BSG; brain stem glioma; Cho; choline; CT; computed tomography; DTI; diffusion tensor imaging; DWI; diffusion weighted imaging; FET; 18F-fluoro-ethyl-tyrosine; FLAIR; fluid-attenuated inversion recovery; GBM; glioblasto

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Changes in zinc status and zinc transporters expression in whole blood of patients with Systemic Inflammatory Response Syndrome (SIRS)

Keywords: برای; ICU; Intensive Care Unit; SIRS; Systemic Inflammatory Response Syndrome; APACHE II; Acute Physiology and Chronic Health Evaluation; SOFA; Sequential Organ Failure Assessment; ZnT/SCL30A (1-10); Solute Carrier Family 30; ZIP/SCL39A (1-14); Solute Carrier F

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Qing brick tea (QBT) aqueous extract protects monosodium glutamate-induced obese mice against metabolic syndrome and involves up-regulation Transcription Factor Nuclear Factor-Erythroid 2-Related Factor 2 (Nrf2) antioxidant pathway

Keywords: برای; MetS; metabolic syndrome; QBT; Qing brick tea; HOMA IR; insulin resistance index; TG; triglyceride; CHO; total cholesterol; MDA; malonaldehyde; ROS; reactive oxygen species; SOD; superoxide dismutase; GPx; glutathione peroxidase; CAT; catalase; GR; glutat

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Identification of novel thiazolo[5,4-d]pyrimidine derivatives as human A1 and A2A adenosine receptor antagonists/inverse agonists

Keywords: برای; AR; adenosine receptor; cAMP; 3′,5′-cyclic adenosine monophosphate; CHO; chinese hamster ovary; DPCPX; 8-cyclopentyl-1,3-dipropyl-xanthine; I-AB-MECA; 4-[((4-amino-3-iodophenyl)methyl)amino]-5′-N-methylcarboxamidoadenosine; ZM 241385; (4-(2-[7-amino

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Role of 6-O-α-maltosyl-β-cyclodextrin in lysosomal cholesterol deprivation in Npc1-deficient Chinese hamster ovary cells

Keywords: برای; 6-O-α-maltosyl-β-cyclodextrin (Mal-βCD); Npc1-deficient cells; Lysosomal unesterified cholesterol; Cholesterol/efflux; Endocytosis; Liquid chromatography-mass spectrometry; βCD; β-cyclodextrin; CHO; Chinese hamster ovary; DAOS; (hydroxy-3-sulfopropyl

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Improving transcriptional activity of human cytomegalovirus major immediate-early promoter by mutating NF-κB binding sites

Keywords: برای; Transcriptional activity; Major immediate-early promoter; NF-κB binding site; Mutation; CMV; cytomegalovirus; MIEP; major immediate-early promoter; SELEX; systematic evolution of ligands by exponential enrichment; HCMV; human cytomegalovirus; CHO; Chines

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Visualisation of intracellular production bottlenecks in suspension-adapted CHO cells producing complex biopharmaceuticals using fluorescence microscopy

Keywords: برای; bsAb; bispecific antibody; CHO; chinese hamster ovary; ER; endoplasmic reticulum; IgG; Immunoglobulin G; DTE; difficult-to-express; DHFR; dihydrofolate reductase; MTX; Methotrexate; VCD; viable cell density; qRT-PCR; quantitative real-time polymerase chai

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

In vivo gamma-aminobutyric acid and glutamate levels in people with first-episode schizophrenia: A proton magnetic resonance spectroscopy study

Keywords: برای; 1H-MRS; proton magnetic resonance spectroscopy; ACC; anterior cingulate cortex; AUC; area under curve; Cho; choline; CI; confidence interval; Cr; creatine; CRLBs; Cramér Rao Lower Bounds; CSF; cerebrospinal fluid; FFE; fast field echo; FWHM; full width

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

A new lipid carrier protein in the cattle tick Rhipicephalus microplus

Keywords: برای; CHO; Free Cholesterol; CHOE; Cholesterol Ester; DAG; Diacylglycerol; FFA; Free Fatty Acids; HC; Hydrocarbons; HPTLC; HighPerformance Thin-layer chromatography; Lp; Lipophorin; MAG; Monoacylglycerol; NL; Neutral Lipids; PL; Phospholipids; RmLCP; Rhipicepha

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

MLN3126, an antagonist of the chemokine receptor CCR9, ameliorates inflammation in a T cell mediated mouse colitis model

Keywords: برای; CCL25; C-C motif chemokine ligand 25; CCR9; C-C chemokine receptor 9; CD; Crohn's disease; CHO; Chinese hamster ovary; FLIPR; fluorometric imaging plate reader; IBD; inflammatory bowel disease; LP; lamina propria; SCID; C.B-17/Icr-scid mice; TNF; tumor ne

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Design and synthesis of 1-(1-benzothiophen-7-yl)-1H-pyrazole, a novel series of G protein-coupled receptor 52 (GPR52) agonists

Keywords: برای; GPR52; G protein-coupled receptor 52; SAR; structure-activity relationship; cAMP; 3′,5′-cyclic adenosine monophosphate; EC50; half maximal effective concentration; MAP; methamphetamine; NMDA; N-methyl-d-aspartate; PK; pharmacokinetic; CHO; Chinese h

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Cholesterol ester hydrolase inhibitors reduce the production of synaptotoxic amyloid-β oligomers

Keywords: برای; AD; Alzheimer's disease; Aβ; amyloid-β; APP; amyloid precursor protein; AACOCF3; arachidonyl trifluoromethyl ketone; CHO; Chinese hamster ovary; CEH; cholesterol ester hydrolase; CM; conditioned media; CSP; cholesteryl N-(2-dimethylaminoethyl) carbamate

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

The beneficial effects of Zn on Akt-mediated insulin and cell survival signaling pathways in diabetes

Keywords: برای; Akt2-KO; Akt2 gene deletion; CHO; Chinese hamster ovary; DM; diabetes mellitus; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; ER; endoplasmic reticulum; GLUT4; glucose transporter type-4; GS; glycogen synthase; GSK-3; glycogen synt

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Targeting phosphatases of regenerating liver (PRLs) in cancer

Keywords: برای; Protein tyrosine phosphatase; Metastasis; Theinopyridone; Structure; CBS; cystathionine-beta-synthase; CHO; Chinese hamster ovary; CNNM; magnesium transporters of cyclin M; EMT; epithelial-mesenchymal transition; HMVEC; human microvascular endothelial c

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

A pilot study of the modulation of sirtuins on arylamine N-acetyltransferase 1 and 2 enzymatic activity

Keywords: برای; Ac-INH; acetyl-Isoniazid; Ac-PABA; acetyl-p-aminobenzoic acid; APC; allophycocyanin; CHO; Chinese hamster ovary cells; DMEM; Dulbecco's modified Eagle's medium; E2F1; E2F transctriptios factor 1; ER81; ETS-related protein 81; FITC; fluorescein IsoTioCyana

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

The tamoxifen derivative ridaifen-B is a high affinity selective CB2 receptor inverse agonist exhibiting anti-inflammatory and anti-osteoclastogenic effects

Keywords: برای; Cannabinoid receptors; G-protein coupled receptors; Inverse agonist; Antagonist; Drug action; AC; adenylyl cyclase; CB1R; cannabinoid receptor type 1; CB2R; cannabinoid receptor type 2; CHO; Chinese hamster ovary; CP-55,940; 5-(1,1-dimethylheptyl)-2-[5-hy

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Curve-linear relationship between altered carbohydrate traits with molecular structure and truly absorbed nutrient supply to dairy cattle in new hulless barley (Hordeum vulgare L.)

Keywords: برای; ABCP; truly absorbed bypass protein in the small intestine; AECP; truly absorbed rumen endogenous protein in the small intestine; AMCP; truly absorbed microbial protein in the small intestine; ARUP; truly absorbed rumen undegradable protein in the small i

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Functional characterization of the dual allatostatin-A receptors in mosquitoes

Keywords: برای; AstA; allatostatin-A; N-terminus; amino-terminus; AstAR; AstA receptor; C-terminus; carboxy-terminus; cDNA; complementary deoxyribonucleic acid; CHO; chinese hamster oocyte; ECL; extracellular loop; EC50; Half maximal effective concentration; ICL; intrace

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

DNA and chromosome damage induced by bleomycin in mammalian cells: An update

Keywords: برای; BLM; bleomycin; CAs; chromosomal aberrations; MN; micronucleus; FISH; fluorescent in situ hybridization; mtDNA; mitochondrial DNA; SCEs; sister-chromatid exchanges; ITSs; interstitial telomeric sequences; γ-H2AX; phosphorylated histone H2AX; PNA; peptide

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

C-C motif chemokine ligand (CCL) production in equine peripheral blood mononuclear cells identified by newly generated monoclonal antibodies

Keywords: برای; CCL; C-C motif chemokine ligand; CHO; Chinese hamster ovary cells; EEC; equine endothelial cells; ERU; equine recurrent uveitis; ETEC; equine tracheal respiratory epithelial cells; FPLC; Fast Protein Liquid Chromatography; MCP; Macrophage Chemoattractant

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Selectively targeting prostanoid E (EP) receptor-mediated cell signalling pathways: Implications for lung health and disease

Keywords: برای; ASM; airway smooth muscle; BAL; bronchoalveolar; CHO; Chinese hamster ovary; COX; cyclooxygenase; EP; prostanoid E; ERK; extracellular signal-regulated kinase; GPCR; G protein-coupled receptors; GSK-3; glucogen synthase kinase-3; HMLC; human lung mast cel

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

The aminopyridine-3,5-dicarbonitrile core for the design of new non-nucleoside-like agonists of the human adenosine A2B receptor

Keywords: برای; G protein-coupled receptors; Adenosine A2B receptor agonists; Aminopyridine-3,5-dicarbonitriles; Ligand-adenosine receptor modelling studies; ABMECA; N6-(4-aminobenzyl)N-methylcarboxamidoadenosine; Ado; Adenosine; AR; adenosine receptor; CHO; Chinese hams

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

The effects of rumen nitrogen balance on in vitro rumen fermentation and microbial protein synthesis vary with dietary carbohydrate and nitrogen sources

Keywords: برای; BCFA; branched-chain fatty acids; CHO; carbohydrates; CP; crude protein; DM; dry matter; GP; in vitro gas production; LAM; liquid-associated microbes; ME; metabolizable energy; N; nitrogen; NH3-N; ammonia-nitrogen; RNB; rumen nitrogen balance; SAM; solid-

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

The effects of 1st and 2nd generation biodiesel exhaust exposure on hematological and biochemical blood indices of Fisher344 male rats - The FuelHealth project

Keywords: برای; ALP; alkaline phosphatase; ALT; alanine aminotransferase; AST; aspartate aminotransferase; CC; carbonyl compounds; CHO; cholesterol; CRE; creatinine; DEE; diesel exhaust emission; DEP; diesel exhaust particles; DPF; diesel particle filter; EPO; erythropoi

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

Stress Adaptation Upregulates Oxytocin within Hypothalamo-Vagal Neurocircuits

Keywords: برای; Che; chronic heterotypic stress; Cho; chronic homotypic stress; CRF; corticotrophin-release factor; CTB; cholera toxin B; DMV; dorsal motor nucleus of the vagus; DVC; dorsal vagal complex; FD; functional dyspepsia; FGIDs; functional gastrointestinal disor

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2018 سفارش ترجمه

Frontal Tumefactive Demyelinating Lesion Mimicking Glioblastoma Differentiated by Methionine Positron Emission Tomography

Keywords: برای; Demyelinating lesion; Glioblastoma; Methionine; PET; Tumefactive; Cho; Choline; Cr; Creatine; GBM; Glioblastoma multiforme; Lac; Lactate; MAID; Monofocal acute inflammatory demyelination; MET PET; Methionine positron emission tomography; MRI; Magnetic res

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2018 سفارش ترجمه

Deficiency in GnRH receptor trafficking due to a novel homozygous mutation causes idiopathic hypogonadotropic hypogonadism in three prepubertal siblings

Keywords: برای; CDGP; constitutional delay of growth and puberty; CHO; Chinese hamster ovary; E2; estradiol; ER; endoplasmic reticulum; FSH; follicle-stimulating hormone; GnRH; gonadotropin-releasing hormone; HEK; human embryonic kidney; H-P-G axis; hypothalamic-pituit

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2018 سفارش ترجمه

Luminescent rhenium(I), ruthenium(II), and iridium(III) polypyridine complexes containing a poly(ethylene glycol) pendant or bioorthogonal reaction group as biological probes and photocytotoxic agents

Keywords: برای; 5CNU; 5-cyanouracil; Ac4ManNAz; 1,3,4,6-tetra-O-acetyl-N-azidoacetyl-d-mannosamine; BARAC; biarylazacyclooctynone; BCN; bicyclo[6.1.0]nonyne; BCN-C10; N-[(1R,8S,9S)-bicyclo[6.1.0]non-4-yn-9-ylmethyloxycarbonyl]-1-aminodecane; bis-BCN; 1,13-bis((1R,8S,9s

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

The ADRA2A rs553668 variant is associated with type 2 diabetes and five variants were associated at nominal significance levels in a population-based case-control study from Mexico City

Keywords: برای; ADRA2A; Alpha-2a-adrenergic receptor; BMI; Body mass index; CHO; Cholesterol; DNA; Deoxyribonucleic acid; ENSANUT; National Survey of Health and Nutrition; FPG; Fasting plasma glucose; GWAS; Genome wide association study; HDL-C; Cholesterol high density l

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

Proteomic analysis of micro-scale bioreactors as scale-down model for a mAb producing CHO industrial fed-batch platform

Keywords: برای; Proteomics; Scale-down model; Micro-bioreactor; Fed-batch; CHO; Monoclonal antibody;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

Glyco-Mapper: A Chinese hamster ovary (CHO) genome-specific glycosylation prediction tool

Keywords: برای; CCM; central carbon metabolism; CHO; Chinese hamster ovary; DReaM-zyP; Discretized Reaction Network Modeling using Fuzzy Parameters; EPO; erythropoietin; mAb; monoclonal antibody; SEAP; secreted alkaline phosphatase; siRNA; short interfering RNA; Chinese

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

Acid Sensing Ion Channel 1a (ASIC1a) Mediates Activity-induced Pain by Modulation of Heteromeric ASIC Channel Kinetics

Keywords: برای; ASIC; acid sensing ion channels; CHO; Chinese hamster ovary; DRG; dorsal root ganglia; EGTA; ethylene glycol-bis(β-aminoethyl ether)-N,N,N′,N′-tetraacetic acid; HEPES; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; MWT; muscle withdrawal thresho

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

The prebiotic inulin improves substrate metabolism and promotes short-chain fatty acid production in overweight to obese men

Keywords: برای; AMPK; adenosine monophosphate (AMP)-activated protein kinase; CHO; carbohydrate; DP; degree of polymerization; FFA; free fatty acid; GLP-1; glucagon-like peptide-1; GPR; G-coupled protein receptor; iAUC; incremental area under the curve; INU; inulin treat

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

Identification of an oxime-containing C-glucosylarene as a potential inhibitor of sodium-dependent glucose co-transporter 2

Keywords: برای; Oxime; Sodium-dependent glucose co-transporter; Aryl C-glycosides; Diabetes management; Ac2O; acetic anhydride; AMG; α-methyl-d-glucopyranoside; BF3·OEt2; boron trifluoride etherate; CHO; Chinese hamster ovary; DMAP; 4-N,N-dimethylaminopyridine; hERG; h

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2018 سفارش ترجمه

Anticancer activity study of A3 adenosine receptor agonists

Keywords: برای; AC; adenylyl cyclase; A3AR; A3 Adenosine receptor; Caco-2; epithelial colorectal carcinoma; CHO; Chinese hamster ovary; Cl-IB-MECA; 2-chloro-N6-(3-iodobenzyl)-adenosine-5′-N-methyluronamide; DMEM; Dulbecco's modified eagle medium; DMSO; dimethyl sulphox

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2018 سفارش ترجمه

Optimization of a high-cell-density polyethylenimine transfection method for rapid protein production in CHO-EBNA1 cells

Keywords: برای; r-protein; recombinant protein; PEI; polyethylenimine; CHO; Chinese Hamster Ovary; TGE; transient gene expression; EBNA1; Epstein Barr virus Nuclear Antigen-1; BCDT; BalanCD Transfectory CHO; Transient gene expression; CHO cells; Recombinant proteins; Mon

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

Identification of homocysteine-suppressive mitochondrial ETC complex genes and tissue expression profile - Novel hypothesis establishment

Keywords: برای; Bet; betaine; BM; bone marrow; C. elegans; caenorhabditis elegans; CBS; cystathionine-β-synthase; CELMP; cardioencephalomyopathy; Cho; choline; CSE; cystathionineγ-lyase; CT; connective tissue; Cysta; cystathionine; D; days; DCC; dog cardiac cells; DD;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

Chemical characterization and cytotoxic, genotoxic, and mutagenic properties of Baccharis trinervis (Lam, Persoon) from Colombia and Brazil

Keywords: برای; CHO; Chinese Hamster Ovary; AE; Aqueous extracts; B; Brazil; C; Colombia; EAF; Ethyl Acetate Fraction; BF; Butanol Extract; ARF; Aqueous Residue Fraction; HPLC; High Performance Liquid Chromatography; HRMS; High Resolution Mass Spectrometry; MTT; 3-(4.5-d

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

Targeting α1 inserted domain (I) of α1β1 integrin by Lebetin 2 from M. lebetina transmediterranea venom decreased tumorigenesis and angiogenesis

Keywords: برای; MIDAS; metal ion-dependent adhesion site MIDAS; L2; Lebetin 2; ANP; atrial natriuretic peptide; BNP; brain or b-type natriuretic peptide; CNP; c-type natriuretic peptide; CHO; Chinese hamster ovary; FCS; fetal calf serum; ECM; extracellular matrix; CAM; c

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

A proton MR spectroscopy study of the thalamus in twins with autism spectrum disorder

Keywords: برای; TD; typically-developing; BAP; broader autism phenotype; SCI; social communication impairments; RRB; restricted and repetitive behaviors; SPA; sensory processing abnormalities; SSP; Short Sensory Profile; MZ; monozygotic; DZ; dizygotic; MRS; magnetic reso

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

Astrocytic γ-aminobutyric acid (GABA) transporters mediate guanidinoacetate transport in rat brain

Keywords: برای; Guanidinoacetate; Creatine; GABA transporter; Astrocyte; GABA; Neuron-glial relationship; aCSF; artificial cerebrospinal fluid; AGAT; l-arginine-glycine amidinotransferase; CHO; Chinese hamster ovary; CRT; creatine transporter; DAPI; 4′,6-diamidino-2-ph

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

An evaluation of lipid metabolism in the insect trypanosomatid Herpetomonas muscarum uncovers a pathway for the uptake of extracellular insect lipoproteins

Keywords: برای; Herpertomonas muscarum; Lipid metabolism; Lipophorin; Insect trypanosomatid; Parasite-vector insect interaction; Sterols; Amu; Atomic mass units; CHO; Cholesterol; CHOE; Esterified cholesterol; DAG; Diacylglycerol; Lp; Lipophorin; 125I-Lp; Radiolabeled Li

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

In-vitro metabolomics to evaluate toxicity of particulate matter under environmentally realistic conditions

Keywords: برای; Particulate matter; Indoor sampling; A549; Cytotoxicity; HP-LC/MS; Metabolomics; ACN; Acetonitrile; CCOHS; Canadian Centre for Occupational Health and Safety; CERs; Ceramides; CHCl3; Chloroform; Cho; Choline; CLs; Cardiolipins; Etn; Ethanolamine; EU; Euro

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

Amino acid misincorporation in recombinant proteins

Keywords: برای; Amino acid misincorporation; Sequence variant analysis; Mass spectrometry; LC-MS/MS; Biopharmaceuticals; CHO; E. coli;

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

α1A-Adrenoceptors activate mTOR signalling and glucose uptake in cardiomyocytes

Keywords: برای; AMPK; 5′ adenosine monophosphate-activated protein kinase; AR; adrenoceptor; CaMKK; calmodulin-dependent protein kinase kinase; CHO; Chinese hamster ovary; Comp C; compound C; DAG; diacylglycerol; IP3; inositol 1,4,5-trisphosphate; mTOR; mechanistic tar

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2018 سفارش ترجمه

Ultra-high resolution brain metabolite mapping at 7 T by short-TR Hadamard-encoded FID-MRSI

Keywords: برای; Ac; acetate; AD; acquisition delay; CAIPIRINHA; controlled aliasing in parallel imaging results in higher acceleration; Cho; choline; CRLB; Cramér-Rao lower bound; Cr; creatine; CSF; cerebrospinal fluid; DIR; double inversion recovery; EPSI; echo-planar

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

Structure-activity relationship studies and pharmacological characterization of N5-heteroarylalkyl-substituted-2-(2-furanyl)thiazolo[5,4-d]pyrimidine-5,7-diamine-based derivatives as inverse agonists at human A2A adenosine receptor

Keywords: برای; G protein coupled receptors; A2A adenosine receptors; Inverse agonists; Thiazolopyrimidine derivatives; Bicyclic heteroaromatic system; AR; adenosine receptor; cAMP; 3′,5′-cyclic adenosine monophosphate; CHO; chinese hamster ovary; DPCPX; 8-cyclopenty

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

Cell cultures in drug discovery and development: The need of reliable in vitro-in vivo extrapolation for pharmacodynamics and pharmacokinetics assessment

Keywords: برای; 3Rs; Reduction, Replacement, Refinement; PBPK; physiologically based pharmacokinetic; 2D; two-dimensional; 3D; three-dimensional; HTS; high-throughput screening; IVIVE; in vitro-in vivo extrapolation; ADME; absorption, distribution, metabolism and excreti

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Development of novel oxazolo[5,4-d]pyrimidines as competitive CB2 neutral antagonists based on scaffold hopping

Keywords: برای; Cannabinoid; CB2 receptor; Neutral antagonist; oxazolo[5,4-d]pyrimidine; Boc; tert-butyloxycarbonyl; cAMP; cyclic adenosine monophosphate; CHO; Chinese hamster ovary cells; CHO-CB2; Chinese hamster ovary cells expressing CB2 receptors; CHO-WT; Chinese ham

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2018 سفارش ترجمه