Keywords: هیپرفرفی عروق کرونر; APL; allosterically potentiating ligand; AD; Alzheimer's disease; Aβ; amyloid-β; ALS; amyotrophic lateral sclerosis; BCCAs; bilateral common carotid arteries stenosis; CTX; cerebral cortex; DAB; diaminobenzidine; Drp1; dynamin-related protein 1; ECTX;
مقالات ISI هیپرفرفی عروق کرونر (ترجمه نشده)
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Keywords: هیپرفرفی عروق کرونر; Chronic cerebral hypoperfusion; Diabetes; Aging; Memory impairment; Brain damage; Neuroinflammation;
Keywords: هیپرفرفی عروق کرونر; Phosphodiesterase inhibitor; Roflumilast; Chronic cerebral hypoperfusion; Memory;
Keywords: هیپرفرفی عروق کرونر; Treadmill exercise; Chronic cerebral hypoperfusion; Blood-brain barrier; Cognitive impairment; White matter injury;
Keywords: هیپرفرفی عروق کرونر; CCH; Chronic cerebral hypoperfusion; AD; Alzheimer's disease; VaD; vascular dementia; BBB; blood brain barrier; CNS; central nervous system; PKC; protein kinase C; mAb; Mouse monoclonal antibody; CREB; cAMP-response element binding protein; BDNF; brain de
Keywords: هیپرفرفی عروق کرونر; Chronic cerebral hypoperfusion; 4-VO/ICA model; Middle-aged rat; Neurodegeneration; Memory; Atorvastatin;
Keywords: هیپرفرفی عروق کرونر; Bilateral common carotid artery occlusion; Chronic cerebral hypoperfusion; Acetylcholine; Morris water maze; Oxidative stress;
Keywords: هیپرفرفی عروق کرونر; Chronic cerebral hypoperfusion; Cognitive impairment; Histone acetylation; NF-E2 related factor 2; Sodium butyrate;
Keywords: هیپرفرفی عروق کرونر; Chronic cerebral hypoperfusion; Middle-aged rat; Memory loss; Cilostazol; Sildenafil; Memory recovery
Keywords: هیپرفرفی عروق کرونر; Luteolin; Chronic cerebral hypoperfusion; Antioxidant; Anti-inflammatory; Amyloid beta
Keywords: هیپرفرفی عروق کرونر; Transient, Global cerebral ischemia; Chronic cerebral hypoperfusion; Retrograde amnesia; Fish oil; Antiamnesic effect; Functional recovery;
Keywords: هیپرفرفی عروق کرونر; Angiotensin-(1-7); Chronic cerebral hypoperfusion; Hippocampus; Nitric oxide; Neuronal loss; Astrocyte proliferation;
Keywords: هیپرفرفی عروق کرونر; vascular dementia; rat; chronic cerebral hypoperfusion; magnetic resonance spectroscopy; microimaging;
Keywords: هیپرفرفی عروق کرونر; Potassium 2-(1-hydroxypentyl)-benzoate; Chronic cerebral hypoperfusion; Oxidative damage; White matter impairment; Astrocyte activation;
Keywords: هیپرفرفی عروق کرونر; Chronic cerebral hypoperfusion; Middle-aged rat; Brain neurodegeneration; Sildenafil; Neuroprotection; Learning deficit;
Keywords: هیپرفرفی عروق کرونر; Oligoemia; Cerebral ischemia; Vascular dysfunction; Cerebrovascular disease; Chronic cerebral hypoperfusion; Cerebral blood flow; Alzheimer's disease; Vascular risk factors;
FoxO1-mediated autophagy plays an important role in the neuroprotective effects of hydrogen in a rat model of vascular dementia
Keywords: هیپرفرفی عروق کرونر; Atg7; autophagy associated gene 7; Bax; Bcl-2 associated X protein; Bak; Bcl-2 homologous antagonist/killer; Bcl-2; B-cell lymphoma-2; Beclin 1; Bcl-2 interacting protein 1; CCH; chronic cerebral hypoperfusion; Cleaved caspase-3; Cleaved cysteinyl asparta
Activation of liver X receptor β-enhancing neurogenesis ameliorates cognitive impairment induced by chronic cerebral hypoperfusion
Keywords: هیپرفرفی عروق کرونر; Liver X receptors; Chronic cerebral hypoperfusion; Phosphoinositide-3-kinase (PI3K)/phosphorylated protein kinase B (Akt); Neural stem cell; Neurogenesis;
HMGB1 Neutralization Attenuates Hippocampal Neuronal Death and Cognitive Impairment in Rats with Chronic Cerebral Hypoperfusion via Suppressing Inflammatory Responses and Oxidative Stress
Keywords: هیپرفرفی عروق کرونر; AD; Alzheimer's disease; BBB; blood-brain barrier; CAT; catalase; CBF; cerebral blood flow; CCH; chronic cerebral hypoperfusion; DAMPs; damage-associated molecular patterns; EB; Evans Blue; HMGB1; High-mobility group box-1; MDA; decreased malondialdeh
Etidronate-zinc Complex Ameliorated Cognitive and Synaptic Plasticity Impairments in 2-Vessel Occlusion Model Rats by Reducing Neuroinflammation
Keywords: هیپرفرفی عروق کرونر; 2-VO; two-vessel occlusion; BPs; bisphosphonates; CCH; chronic cerebral hypoperfusion; COX-2; cyclooxygenase-2; DEP; depotentiation; Eti; etidronate; Eti-Zn; etidronate-zinc complex; fEPSP; field excitatory postsynaptic potential; Iba1; ionized calciu
Nimodipine attenuates tau phosphorylation at Ser396 via miR-132/GSK-3β pathway in chronic cerebral hypoperfusion rats
Keywords: هیپرفرفی عروق کرونر; Chronic cerebral hypoperfusion; Tau phosphorylation; GSK-3β; miR-132; Nimodipine; Rat;
Clitoria ternatea L. root extract ameliorated the cognitive and hippocampal long-term potentiation deficits induced by chronic cerebral hypoperfusion in the rat
Keywords: هیپرفرفی عروق کرونر; CCH; chronic cerebral hypoperfusion; CT; Clitoria ternatea L.; CA1; Cornu Ammonis 1; PBOCCA; permanent bilateral occlusion of common carotid arteries; LTP; long-term potentiation; VaD; vascular dementia; AD; Alzheimer's disease; NMDA; N-methyl-d-aspartate
MCP-1-mediated activation of microglia promotes white matter lesions and cognitive deficits by chronic cerebral hypoperfusion in mice
Keywords: هیپرفرفی عروق کرونر; MCP-1; Microglia; White matter lesions; Chronic cerebral hypoperfusion;
Inhibition of SENP3 by URB597 ameliorates neurovascular unit dysfunction in rats with chronic cerebral hypoperfusion
Keywords: هیپرفرفی عروق کرونر; 2VO; 2-vessel occlusion; Bax; Bcl-2-associated X protein; BBB; blood-brain barrier; Bcl; B cell lymphoma; Caspase3; cysteinyl aspartate specific proteinase 3; CCH; chronic cerebral hypoperfusion; DHE; dihydroethidium; ECM; extracellular matrix; ECS; endoc
Neuroprotective and axonal outgrowth-promoting effects of tetramethylpyrazine nitrone in chronic cerebral hypoperfusion rats and primary hippocampal neurons exposed to hypoxia
Keywords: هیپرفرفی عروق کرونر; Chronic cerebral hypoperfusion; Oxygen glucose deprivation; Tetramethylpyrazine nitrone; Neuroprotection; Axonal outgrowth;
URB597 improves cognitive impairment induced by chronic cerebral hypoperfusion by inhibiting mTOR-dependent autophagy
Keywords: هیپرفرفی عروق کرونر; 3-MA; 3-methyladenine; ACSF; artificial cerebrospinal fluid; AD; Alzheimer's disease; BCCAO; bilateral common carotid artery occlusion; CCH; chronic cerebral hypoperfusion; CNS; central nervous system; ECS; endocannabinoid system; EM; electron microscop
Interleukin-1β impedes oligodendrocyte progenitor cell recruitment and white matter repair following chronic cerebral hypoperfusion
Keywords: هیپرفرفی عروق کرونر; Chronic cerebral hypoperfusion; Interleukin-1β (IL-1β); IL-1 receptor type 1 (IL-1R1); Oligodendrocyte progenitor cells (OPCs); Recruitment; White matter;
Chronic cerebral hypoperfusion independently exacerbates cognitive impairment within the pathopoiesis of Parkinson's disease via microvascular pathologys
Keywords: هیپرفرفی عروق کرونر; PD; Parkinson's disease; CHH; chronic cerebral hypoperfusion; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; BCCAs; bilateral common carotid arteries stenosis; PDCN; Parkinson's disease with normal cognitive performance; PD-MCI; Parkinson's disease w
Fluoxetine ameliorates cognitive impairments induced by chronic cerebral hypoperfusion via down-regulation of HCN2 surface expression in the hippocampal CA1 area in rats
Keywords: هیپرفرفی عروق کرونر; Fluoxetine; Chronic cerebral hypoperfusion; Cognitive impairments; HCN2 subunit;
The Effect of Sympathetic Denervation on Cerebral Arteriogenesis After Chronic Cerebral Hypoperfusion
Keywords: هیپرفرفی عروق کرونر; Chronic cerebral hypoperfusion; Cerebral collateral arteriogenesis; Perivascular sympathetic nerve
Research reportBaclofen ameliorates spatial working memory impairments induced by chronic cerebral hypoperfusion via up-regulation of HCN2 expression in the PFC in rats
Keywords: هیپرفرفی عروق کرونر; GABAB receptors; Chronic cerebral hypoperfusion; Spatial working memory; HCN subunits; PFC;
Leonurine ameliorates cognitive dysfunction via antagonizing excitotoxic glutamate insults and inhibiting autophagy
Keywords: هیپرفرفی عروق کرونر; Chronic cerebral hypofusion; Long-term depression; Leonurine; Hippocampus; Autophagy; CCH; Chronic cerebral hypoperfusion; OGD; oxygen-glucose deprivation; aCSF; artificial cerebral spinal fluid; 2-VO; bilateral common carotid arteries; NMDARs; N-methyl
Ginkgo biloba L. extract protects against chronic cerebral hypoperfusion by modulating neuroinflammation and the cholinergic system
Keywords: هیپرفرفی عروق کرونر; Chronic cerebral hypoperfusion; Choline acetyltransferase; Ginkgo biloba; Neuroinflammation; Toll-like receptor; Ang-II; angiotensin II; BCCAo; Bilateral common carotid artery occlusion; CCH; chronic cerebral hypoperfusion; ChAT; choline acetyltransferase
Research reportCilostazol reduces blood brain barrier dysfunction, white matter lesion formation and motor deficits following chronic cerebral hypoperfusion
Keywords: هیپرفرفی عروق کرونر; Cerebral small vessel disease; Blood brain barrier permeability; Chronic cerebral hypoperfusion; Circulating microparticles; Cilostazol; Gait disturbance;
Research reportCannabinoid receptor agonist WIN55,212-2 and fatty acid amide hydrolase inhibitor URB597 may protect against cognitive impairment in rats of chronic cerebral hypoperfusion via PI3K/AKT signaling
Keywords: هیپرفرفی عروق کرونر; Endocannabinoid system; Chronic cerebral hypoperfusion; Cognitive impairment; PI3K/AKT signaling;
Chronic cerebral hypoperfusion induces memory deficits and facilitates Aβ generation in C57BL/6J mice
Keywords: هیپرفرفی عروق کرونر; Alzheimer's disease; Chronic cerebral hypoperfusion; APP; Aβ; Cognitive impairment;
Activation of GABAB2 subunits alleviates chronic cerebral hypoperfusion-induced anxiety-like behaviours: A role for BDNF signalling and Kir3 channels
Keywords: هیپرفرفی عروق کرونر; Anxiety-like behaviour; Chronic cerebral hypoperfusion; GABAB2 subunit; BDNF/TrkB/NCAM; Kir3 channels; 2VO; two-vessel occlusion; GABAB; γ-aminobutyric acid type B; CA1; Cornu ammonis 1; MWM; Morris water maze test; NOR; novel object recognition test; OF
Everolimus (RAD001) ameliorates vascular cognitive impairment by regulating microglial function via the mTORC1 signaling pathway
Keywords: هیپرفرفی عروق کرونر; VaD; vascular dementia; mTORC1; mammalian target of rapamycin complex 1; AD; Alzheimer's disease; ROS; reactive oxygen species; GWAS; genome-wide association study; IFN; interferon; TNF-α; tumor necrosis factor alpha; IL; interleukin; Arg-1; arginase-1;
Icariin, a major constituent of flavonoids from Epimedium brevicornum, protects against cognitive deficits induced by chronic brain hypoperfusion via its anti-amyloidogenic effect in rats
Keywords: هیپرفرفی عروق کرونر; Icariin; Permanent occlusion of bilateral common carotid arteries; Chronic cerebral hypoperfusion; Beta-amyloid; Transforming growth factor-β1 signaling
BMSCs transplantation improves cognitive impairment via up-regulation of hippocampal GABAergic system in a rat model of chronic cerebral hypoperfusion
Keywords: هیپرفرفی عروق کرونر; AD; Alzheimer's diseases; ANOVA; analysis of variance; BMSCs; bone marrow mesenchymal stem cells; BrdU; bromo-2-deoxy uridine; EDTA; ethylenediaminetetraacetic acid; GABA; gamma amino butyric acid; GABABR1; GABAB receptor 1; GAD; glutamic acid decarboxy
Long-lasting spatial learning and memory impairments caused by chronic cerebral hypoperfusion associate with a dynamic change of HCN1/HCN2 expression in hippocampal CA1 region
Keywords: هیپرفرفی عروق کرونر; Chronic cerebral hypoperfusion; Spatial learning and memory impairments; HCN1 subunit; HCN2 subunit
Cannabinoid receptor agonist WIN55,212-2 and fatty acid amide hydrolase inhibitor URB597 suppress chronic cerebral hypoperfusion-induced neuronal apoptosis by inhibiting c-Jun N-terminal kinase signaling
Keywords: هیپرفرفی عروق کرونر; AD; Alzheimer's disease; AEA; anandamide; Bax; Bcl-2-associated X protein; BCCAo; bilateral common carotid artery occlusion; Bcl; B cell lymphoma; CCH; chronic cerebral hypoperfusion; DAPI; 4â²,6-diamidino-2-phenylindole; DMSO; dimethyl sulfoxide; ECS;
Effects of chronic cerebral hypoperfusion and low-dose progesterone treatment on apoptotic processes, expression and subcellular localization of key elements within Akt and Erk signaling pathways in rat hippocampus
Keywords: هیپرفرفی عروق کرونر; 2VO; bilateral common carotid artery occlusion; Akt; protein kinase B; Casp 3; caspase 3; CCH; chronic cerebral hypoperfusion; Cyt C; cytochrome c; EDTA; ethylenediaminetetraacetic acid; EGTA; ethylene glycol tetraacetic acid; EPM; elevated plus maze; Erk
Ecto-5â²-nucleotidase (CD73) is involved in chronic cerebral hypoperfusion-induced white matter lesions and cognitive impairment by regulating glial cell activation and pro-inflammatory cytokines
Keywords: هیپرفرفی عروق کرونر; Abs; antibodies; ANOVA; analysis of variance; BCAS; bilateral common carotid artery stenosis; CCAs; common carotid arteries; CCH; chronic cerebral hypoperfusion; CNS; central nervous system; EAE; experimental autoimmune encephalomyelitis; ELISA; enzyme-li
Lipoxin A4 methyl ester ameliorates cognitive deficits induced by chronic cerebral hypoperfusion through activating ERK/Nrf2 signaling pathway in rats
Keywords: هیپرفرفی عروق کرونر; Lipoxin A4 methyl ester; Chronic cerebral hypoperfusion; Learning and memory; Extracellular signal regulated kinase; Nuclear factor erythroid 2-related factor 2; Antioxidation;
Catalpol promotes oligodendrocyte survival and oligodendrocyte progenitor differentiation via the Akt signaling pathway in rats with chronic cerebral hypoperfusion
Keywords: هیپرفرفی عروق کرونر; Catalpol; Oligodendrocyte; Oligodendrocyte progenitor; Akt; White matter lesions; Chronic cerebral hypoperfusion
Neurohistological and behavioral changes following the four-vessel occlusion/internal carotid artery model of chronic cerebral hypoperfusion: Comparison between normotensive and spontaneously hypertensive rats
Keywords: هیپرفرفی عروق کرونر; 4-VO/ICA model; Chronic cerebral hypoperfusion; Chronic hypertension; Aging; neurodegeneration; Memory impairment
Chronic brain ischemia induces the expression of glial glutamate transporter EAAT2 in subcortical white matter
Keywords: هیپرفرفی عروق کرونر; APC; adenomatous polyposis coli; CBF; cerebral blood flow; EAAT; excitatory amino acid transporter; GFAP; glial-fibrillary acidic protein; GSTÏ; glutathione-S-transferase pi; LBCCA; ligation of bilateral common carotid arteries; MCAO; middle cerebral art
Rosiglitazone treatment reduces hippocampal neuronal damage possibly through alleviating oxidative stress in chronic cerebral hypoperfusion
Keywords: هیپرفرفی عروق کرونر; Oxidative stress; Chronic cerebral hypoperfusion; Rosiglitazone;
Increased serum S100B concentration correlates with hippocampal S100B overexpression and cellular damage following chronic cerebral hypoperfusion
Keywords: هیپرفرفی عروق کرونر; Chronic cerebral hypoperfusion; Serum; Hippocampus; S100B; Rat