Keywords: Colorectal cancer; Cytokines; Immune response; Immunotherapy; Inflammation; Anatomical subsite heterogeneity; CIMP; CpG island methylator phenotype; CIN; chromosomal instability; CRC; colorectal cancer; FGF-2; fibroblast growth factor 2 (basic); G-CSF; gr
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Keywords: CIMP; CpG island methylator phenotype; CIN; Chromosome instability; CRC; Colorectal cancer; CS; CIN score; FISH; Fluorescent in situ hybridization; I-CRC; Interval CRC; IHC; Immunohistochemistry; MMR; DNA mismatch repair; MPE; Molecular pathologic epidemi
Keywords: 5mc; 5-methyl cytosine; 5hmc; 5-hydroxymethylcytosine; ALL; Acute Lymphoblastic Leukemia; ASE; Allele-specific gene expression; B-All; B-cell precursor lineage ALL; CpG; CG dinucleotide; CGI; CpG island; CIMP; CpG island methylator phenotype; DMCs; Differ
Keywords: AMPK-GLUT1; AMP-activated protein kinase-glucose transporter 1; Bax; bcl-2 associated X protein; Bcl-2; B-cell lymphoma gene 2; Bim; bcl-2-like 4; BRAF; v-raf murine sarcoma viral oncogene homolog B1; Cdk; cyclin-dependent kinase; CIMP; CpG island methyla
Keywords: APC; Antigen presenting cells; CIMP; CpG island methylator phenotype; CIN; chromosomal instability; CRC; colorectal cancer; CTLA-4; cytotoxic T lymphocyte-associated protein 4; DAMPs; danger-associated molecular patterns; FDA; US Food and Drug Administr
Keywords: 5mC; 5- hydroxymethylcytosine; AML; acute myeloid leukemia; BET; bromodomain inhibitors; CCOC; clear cell ovarian cancer; ctDNA; cell-free tumor DNA; ChIP-on-chip; chromatin immunoprecipitation with DNA microarray; CIMP; CpG island methylator phenotype; C
Keywords: aCGH; array comparative genomic hybridization; CIMP; CpG island methylator phenotype; CIN; chromosomal instability; CNA; copy number alteration; CRC; colorectal cancer; DFS; disease-free survival; EOCRC; early-onset colorectal cancer; GII; genomic Instabi
Keywords: Colorectal cancer; CIMP; Epigenetic alterations; Biomarkers; Prognosis; Treatment;
Keywords: Gastric Cancer; Cancer Genomics; Molecular Classification; Preclinical Models; CIMP; CpG island methylator phenotype; CIN; chromosomally unstable/chromosomal instability; EBV; Epstein-Barr virus; GAPPS; gastric adenocarcinoma and proximal polyposis of the
Keywords: Lymphoma; Methylation; Decitabine; Marginal zone; MALT; CIMP;
Keywords: Diallyl sulfide; Mitotic arrest; Cell death; Autophagic flux; Zebrafish xenografts; Baf; bafilomycin A1; BRAF; v-Raf murine sarcoma viral oncogene homolog B; CFAs; colony formation assays; CHCA; α-cyano-4-hydroxy-cinnamic acid; CHX; cycloheximide; CIMP;
Keywords: Microorganism; Gastrointestinal carcinoma; Tumor location; CagA; cytotoxin-associated gene A; CIMP; CpG island methylator phenotype; EAC; esophageal adenocarcinoma; ESCC; esophageal squamous cell carcinoma; MSI; microsatellite instability; NOD; nucleotide
Keywords: CD; cytologic dysplasia; CIMP; CpG island methylator phenotype; CRC; colorectal cancer; MINT; methylated in tumor; SSA/P; sessile serrated adenoma/polyp; TSA; traditional serrated adenoma;
Keywords: CRC; colorectal cancer; SNP; single nucleotide polymorphism; CNV; copy number variant; GWAS; genome-wide association studies; GO; gene ontology; BP; biological process; CAM; cell adhesion molecule; CIN; chromosomal instability; MSI; microsatellite instabi
Keywords: ABC transporter; ATP-binding cassette transporter; CAF; cancer-associated fibroblasts; CSCs; cancer stem cells; CTR1; Copper transporter 1; CIMP; CpG island methylator phenotype; CRC; colorectal cancer; DPD; dihydropyrimidine dehydrogenase; ECM; extracell
Keywords: CI; confidence interval; CIMP; CpG island methylator; RR; risk ratio;
Keywords: Predictive Markers; Prognostic Markers; Colorectal Cancer; Molecular Subtypes; RAS; BRAF; MSI; DNA Mismatch Repair; Immunotherapy; Targeted Therapy; Biologics; Anti-EGFR; Anti-VEGF; CCS; colon cancer subtypes; CIMP; CpG island methylator phenotype; CIN; c
Keywords: Alternative medicine; Complementary therapies; Integrative medicine; Massage therapy; CIMP; Complementary Integrative Medicine Program; CVS; Division of Cardiovascular Surgery;
Keywords: Serrated polyp; Traditional serrated adenoma; CIMP; KRAS; BRAF
Keywords: MSI-H; microsatellite instability high; MSS; microsatellite stable; PAM; prediction analysis for microarrays; IL 1B; interleukin 1B; TYMS; thymidylate synthase; MDX 1100; monoclonal antibody MDX 1100; CIMP; CpG island methylator phenotype; BAT25; mononucl
Keywords: Cancer Genetics; Cancer Genomics; Gastric Cancer; CIMP; CpG island methylation phenotype; CIN; Chromosomal instability; EBV; Epstein-Barr virus; EMT; epithelial-mesenchymal transition; GC; gastric cancer; GS; genome stable; Helicobacter pylori; H pylori;
Keywords: Oncogene; Methylation; Serrated Colorectal Cancer; Prognostic Factor; CI; confidence interval; CRC; colorectal cancer; CIMP; CpG island methylator phenotype; HR; hazard ratio; MSI; microsatellite instability; MSS; microsatellite stable; PMR; percentage of
Keywords: AK; adenylate kinase; ANT; adenine nucleotide translocator; AP5A; diadenosine pentaphosphate; BSA; bovine serum albumin; BB-CK; - brain type creatine kinase; CAT; carboxyatractyloside; CIMP; CpG island methylator phenotype; COX; cytochrome c oxidase; CK
Keywords: Genetic Testing; Cancer Genetics; Hereditary Cancer Syndromes; CIMP; CpG island methylator phenotype; FAP; familial adenomatous polyposis; HNPCC; hereditary non-polyposis colorectal cancer; JPS; juvenile polyposis syndrome; MAP; MutYH-associated polyposis
Keywords: cNMPs; Nucleotidyl cyclases; Phosphodiesterases; Protein kinases; Bacterial toxins; Second messengers; AC; adenylyl cyclase; cAMP; adenosine 3â²,5â²-cyclic monophosphate; CC; cytidylyl cyclase; cCMP; cytidine 3â²,5â²-cyclic monophosphate; cGMP; guanos
Keywords: CIMP; CpG island methylator phenotype; CRC; colorectal cancer; MSI; microsatellite instability; SSA/P; sessile serrated adenoma/polyp; SSA/P-D; sessile serrated adenoma/polyp with cytologic dysplasia;
Keywords: cAMP; adenosine 3â²,5â²-cyclic monophosphate; cGMP; guanosine 3â²,5â²-cyclic monophosphate; cCMP; cytidine 3â²,5â²-cyclic monophosphate; cNMP; 3â²,5â²-cyclic nucleoside monophosphate; cUMP; uridine 3â²,5â²-cyclic monophosphate; cTMP; thymidine 3
Keywords: Molecular Epidemiology; Colon Cancer; Prognostic Factor; Integrated Pathways; CI; confidence interval; CIMP; CpG island methylator phenotype; CRC; colorectal cancer; IWHS; Iowa Women's Health Study; MSI; microsatellite instability; PCR; polymerase chain
Keywords: Serrated polyps; serrated polyposis; appendix; KRAS; BRAF; CIMP
Vitamin D status after colorectal cancer diagnosis and patient survival according to immune response to tumour
Keywords: Clinical outcome; Immunology; Molecular pathological epidemiology; Precision medicine; Tumour microenvironment; 25(OH)D; 25-hydroxyvitamin D; BMI; body mass index; CI; confidence interval; CIMP; CpG island methylator phenotype; FFPE; formalin-fixed paraff
Crystal structure and substrate specificity of ExoY, a unique T3SS mediated secreted nucleotidyl cyclase toxin from Pseudomonas aeruginosa
Keywords: X-ray crystallography; Nucleotidyl cyclase toxins; T3SS; Anthrax toxA family; Non-canonical secondary messengers; One-metal-ion dependent catalysis; ExoY; exogenous toxin Y; T3SS; Type III secretory systems; AA-NC; actin-activated nucleotidyl cyclase; EF;
Readers of DNA methylation, the MBD family as potential therapeutic targets
Keywords: NuRD; nucleosome remodeling and deacetylase; CpG; cytosine-guanosine dinucleotide; mCpG; 5-methylcytosine-guanosine dinucleotide; MBD; 5-methylcytosine binding domain; DNMT; DNA methyltransferase; CGI; CpG island; TET; ten-eleven translocation dioxygenase
NDRG2, suppressed expression associates with poor prognosis in pancreatic cancer, is hypermethylated in the second promoter in human gastrointestinal cancers
Keywords: NDRG2; Hypermethylation; Type II transcript; Gastrointestinal cancers; NDRG2; N-myc downstream regulated gene 2; 5-aza-dC; 5-Aza-2'deoxycytidine; TSA; Trichostatin A; qRT-PCR; quantitative reverse transcription polymerase chain reaction; cDNA; complementa
Cardiovascular Complications of Cancer Therapy
Keywords: cancer therapy; cardiomyopathy; cardiovascular complication; ischemia; 5-FU; 5-fluorouracil; ACS; acute coronary syndrome(s); ATE; arterial thrombotic event; CAD; coronary artery disease; CIMP; chemotherapy-induced cardiomyopathy; cTnI; cardiac troponin I
Integrating RNA sequencing into neuro-oncology practice
Keywords: CNS; central nervous system; RNA-seq; RNA sequencing; qRT-PCR; quantitative reverse transcription polymerase chain reaction; NGS; next-generation sequencing; GBM; glioblastoma; SNPs; single nucleotide polymorphisms; exRNAs; extracellular RNAs; lncRNAs; lo
Original StudyEvaluation of CpG Island Methylator Phenotype as a Biomarker in Colorectal Cancer Treated With Adjuvant Oxaliplatin
Keywords: CIMP; Methylation; MSI; Prognosis; Survival;
Association of cigarette smoking and microRNA expression in rectal cancer: Insight into tumor phenotype
Keywords: microRNAs; Smoking; Rectal; Neoplasms; Life style; CIMP; MSI;
Hypermethylation in gastric cancer
Keywords: 5-hmC; 5-hydroxymethylcytosine; 5-mC; 5-methylcytosine; ADAM23; ADAM metallopeptidase domain 23; APC; adenomatosis polyposis coli; ATP; adenosine-triphosphate; BCL6B; B-Cell CLL/Lymphoma 6, Member B; BGS; bisulfite genomic sequencing; BMP-2; bone morphoge
Original ResearchFull Report: Clinical-Alimentary TractMolecular Markers Identify Subtypes of Stage III Colon Cancer Associated With Patient Outcomes
Keywords: Colorectal Cancer; Oncogene; Prognostic Factor; Genetics; CI; confidence interval; CIMP; CpG island methylator phenotype; CIN; chromosomal instability; CRC; colorectal cancer; DFS; disease-free survival; dMMR; deficient DNA mismatch repair; FOLFOX; 5-fluo
Temporal and organ-specific detection of cNMPs including cUMP in the zebrafish
Keywords: Cyclic CMP; Cyclic UMP; Zebrafish; cAMP; adenosine 3â²,5â²-cyclic monophosphate; cCMP; cytidine 3â²,5â²-cyclic monophosphate; cGMP; guanosine 3â²,5â²-cyclic monophosphate; cIMP; inosine 3â²,5â²-cyclic monophosphate; cNMP; nucleoside 3â²,5â²-cycl
Sessile Serrated Adenomas: An Evidence-Based Guide to Management
Keywords: Sessile Serrated Adenoma; Sessile Serrated Polyp; Serrated Neoplasia; Colorectal Cancer Screening; Colonoscopy; Endoscopic Detection; Polypectomy; CI; confidence interval; CIMP; CpG island methylator phenotype; CRC; colorectal cancer; CT; computed tomogra
Genetics and Genetic Biomarkers in Sporadic Colorectal Cancer
Keywords: Genomic Instability; Microsatellite Instability; Chromosomal Instability; CIMP; ACF; aberrant crypt focus; CIMP; CpG island methylator phenotype; CIN; chromosomal instability; Cox-2; cyclo-oxygenase-2; CRC; colorectal cancer; EGFR; epithelial growth facto
PDE7A1 hydrolyzes cCMP
Keywords: A549; human lung carcinoma cell line; AMP; adenosine 5â²-monophosphate; cAMP; adenosine 3â²,5â²-cyclic monophosphate; B103; rat neuroblastoma cells; CMP; cytidine 5â²-monophosphate; cCMP; cytidine 3â²,5â²-cyclic monophosphate; CyaA; Bordetella pertu
Epigenetic biomarkers of colorectal cancer: Focus on DNA methylation
Keywords: Colorectal cancer; Epigenetics; DNA methylation; CIMP; One-carbon metabolism; Folate; Biomarkers; Polymorphism
Colorectal Carcinomas With CpG Island Methylator Phenotype 1 Frequently Contain Mutations in Chromatin Regulators
Keywords: Colon Cancer; Hypermethylation; Microsatellite Instability; Gene Silencing; CIMP; CpG island methylator phenotype; CRC; colorectal carcinoma; SNP; single-nucleotide polymorphism; TCGA; The Cancer Genome Atlas;
Differences in DNA Methylation Signatures Reveal Multiple Pathways of Progression From Adenoma to Colorectal Cancer
Keywords: Epigenetic Modifications; Colon Cancer; Progression; Gene Regulation; adenoma-H; high methylator phenotype adenoma; adenoma-L; low methylator phenotype adenoma; CIMP; CpG island methylator phenotype; CRC; colorectal cancer; DMP; differentially methylated
Clinical Subtypes and Molecular Characteristics of Serrated Polyposis Syndrome
Keywords: Serrated Polyps; Molecular Markers; Hypermethylation; Hyperplastic Polyps; BMI; body mass index; CIMP; CpG island methylator phenotype; CRC; colorectal cancer; SD; standard deviation; SPS; serrated polyposis syndrome; WHO; World Health Organization;
Serrated Colon Polyps as Precursors to Colorectal Cancer
Keywords: Serrated Polyps; Sessile Serrated Adenomas; Serrated Polyposis Syndrome; Colon Cancer; CIMP; CpG island-methylator phenotype; CRC; colorectal carcinoma; HP; hyperplastic polyp; MMR; mismatch repair; MSI; microsatellite instability; MSI-H; high-frequency M
Relationship of colonoscopy-detected serrated polyps with synchronous advanced neoplasia in average-risk individuals
Keywords: CIMP; CpG island methylation phenotype; CRC; colorectal cancer; HP; hyperplastic polyp; LSP; large serrated polyp; MSI-H; high degree of microsatellite instability; SSA; sessile serrated adenoma; TSA; traditional serrated adenoma;
The cutting edge of serrated polyps: a practical guide to approaching and managing serrated colon polyps
Keywords: CIMP; CPG island methylator phenotype; CRC; colorectal carcinoma; GCHP; goblet cell-rich hyperplastic polyp; MPHP; mucin-poor hyperplastic polyp; MSI; microsatellite instability; MVHP; microvesicular hyperplastic polyp; SSA/P; sessile serrated adenoma/p