Keywords: CM، شرایط محیطی; 1-DE, one-dimensional gel electrophoresis; 2-DE, two-dimensional gel electrophoresis; AB, apoptotic body; SCX, strong cation exchange chromatography; CM, conditioned medium; DC, differential centrifugation; DGC, density gradient centrifugation; ESI, elect
مقالات ISI CM، شرایط محیطی (ترجمه نشده)
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Keywords: CM، شرایط محیطی; MeHg, methylmercury; CNS, central nervous system; NGF, nerve growth factor; BDNF, brain-derived neurotrophic factor; NT-3, neurotrophin-3; NT-4/5, neurotrophin-4/5; Trk, tropomyosin related kinase; CM, conditioned medium; MTT, 3-[4,5-dimethylthiazol-2-yl]
Keywords: CM، شرایط محیطی; CNS, central nervous system; CM, conditioned medium; DAPI, 4′, 6-diamidino-2-phenylindole dihydrochloride; DMEM, Dulbecco's modified Eagle medium; ELISA, enzyme-linked immunosorbent assay; ERK, extracellular signal-regulated kinase; FBS, fetal bovine seru
Keywords: CM، شرایط محیطی; CM, conditioned medium; DM, differentiation medium; ECM, extracellular matrix; GM, growth medium; iTRAQ®, isobaric tags for relative and absolute quantitation; MS, mass spectrometryMyokine; Skeletal muscle; Proteome; Growth factor; Differentiation
Combined replacement effects of human modified β-hexosaminidase B and GM2 activator protein on GM2 gangliosidoses fibroblasts
Keywords: CM، شرایط محیطی; CI-M6PR, cation-independent M6P receptor; CM, conditioned medium; ERT, enzyme replacement therapy; GM2, GM2 ganglioside; GM2A, GM2 activator protein; Hex, β-hexosaminidase; LAMP-1, lysosomal associated membrane protein 1; LSD, lysosomal storage disease; M
Neuromedin U is upregulated by Snail at early stages of EMT in HT29 colon cancer cells
Keywords: CM، شرایط محیطی; CM, conditioned medium; CRC, colorectal cancers; CIMP, CpG island methylation phenotype; CIN, chromosomal instability; DEGs, differentially expressed genes; EGF, epidermal growth factor; EMT, epithelial-mesenchymal transition; IPA, Ingenuity Pathway Analy
Anti-neuroinflammatory and neuroprotective effects of the Lindera neesiana fruit in vitro
Keywords: CM، شرایط محیطی; Lindera neesiana; Neuroprotection; Anti-apoptosis; Anti-oxidant; NeuroinflammationANOVA, analysis of variance; Bcl-2, B cell lymphoma; CM, Conditioned medium; CNS, Central nervous system; COX2, Cyclooxygenases 2; DMEM, Dulbecco's modified Eagle medium; DM
SULF2, a heparan sulfate endosulfatase, is present in the blood of healthy individuals and increases in cirrhosis
Keywords: CM، شرایط محیطی; 4-MUS, 4-methylumbelliferyl sulfate; 6OS, 6-O-sulfate; CM, conditioned medium; HAMA, human anti-mouse antibodies; HD, hydrophilic domain; HSPG, heparan sulfate proteoglycan; IPF, idiopathic pulmonary fibrosis; TMB, 3,3′,5,5′-tetramethylbenzidineSULF2; Ext
Novel CT domain-encoding splice forms of CTGF/CCN2 are expressed in B-lineage acute lymphoblastic leukaemia
Keywords: CM، شرایط محیطی; pre-B ALL, precursor B cell acute lymphoblastic leukaemia; mRNA, messenger RNA; qRT-PCR, quantitative real-time polymerase chain reaction; RT-PCR, reverse-transcriptase polymerase chain reaction; CM, conditioned medium; NMD, nonsense-mediated decay; DN, d
Single chain precursor prohaptoglobin promotes angiogenesis by upregulating expression of vascular endothelial growth factor (VEGF) and VEGF receptor2
Keywords: CM، شرایط محیطی; Hp, haptoglobin; proHp, prohaptoglobin; Clr-LP, complement Clr-like protein; HUVECs, human umbilical vein endothelial cells; EPC, endothelial progenitor cells; EGM, endothelial growth medium; EBM, endothelial basal medium; CM, conditioned medium; VEGFR, v
CCL5 promotes vascular endothelial growth factor expression and induces angiogenesis by down-regulating miR-199a in human chondrosarcoma cells
Keywords: CM، شرایط محیطی; VEGF, vascular endothelial growth factor; miRNAs, microRNAs; MMP-3, matrix metalloproteinase-3; CM, conditioned medium; JJ012, human chondrosarcoma cell line; EPCs, endothelial progenitor cells; PBMCs, peripheral blood mononuclear cells; CAM, chorioallant
Secretory prostate apoptosis response (Par)-4 sensitizes multicellular spheroids (MCS) of glioblastoma multiforme cells to tamoxifen-induced cell death
Keywords: CM، شرایط محیطی; CM, conditioned medium; GBM, glioblastoma multiforme; LGG, low grade gliomas; MCS, multicellular spheroids; TAM, tamoxifen; TCGA, The Cancer Genome AtlasGlioblastoma; Par-4; Drug resistance; Multicellular spheroids (MCS); Tamoxifen; Cytotoxicity
Differentiated tonsil-derived mesenchymal stem cells embedded in Matrigel restore parathyroid cell functions in rats with parathyroidectomy
Keywords: CM، شرایط محیطی; Parathyroid cells; Parathyroid hormone (PTH); Tonsil-derived mesenchymal stem cells (TMSC); Parathyroidectomy (PTX); Matrigel (MA)CaSR, calcium sensing receptor; CHGA, chromogranin; CM, conditioned medium; cCM, CM collected from the non-differentiated con
Blockade of VEGF-C and VEGF-D modulates adipose tissue inflammation and improves metabolic parameters under high-fat diet
Keywords: CM، شرایط محیطی; Vegfc; Obesity; Adipose tissue; Inflammation; MacrophagessR3, soluble-VEGFR-3; HFD, high-fat diet; SWAT, subcutaneous white adipose tissue; EWAT, epididymal white adipose tissue; CM, conditioned medium
γ-Irradiated cord blood MNCs: Different paracrine effects on mature and progenitor endothelial cells
Keywords: CM، شرایط محیطی; BM, bone marrow; CB, cord blood; CB-MNCs, umbilical cord blood-derived MNCs; CM, conditioned medium; EBM2, endothelial basal medium; ECs, endothelial cells; ECFCs, endothelial-colony forming cells; EGF, epidermal growth factor; EGM2, endothelial complete
IMM-H004, a novel coumarin derivative compound, attenuates the production of inflammatory mediatory mediators in lipopolysaccharide-activated BV2 microglia
Keywords: CM، شرایط محیطی; CNS, central nervous system; Aβ, β-amyloid; LPS, lipopolysaccharide; CM, conditioned medium; TNF-α, tumor necrosis factor-α; IL, interleukin; NO, nitric oxide; ROS, reactive oxygen species; NF-κB, nuclear factor kappa B; MAPK, mitogen-activated protein ki
Tissue-Infiltrating Neutrophils Constitute the Major In Vivo Source of Angiogenesis-Inducing MMP-9 in the Tumor Microenvironment 12
Keywords: CM، شرایط محیطی; BM, bone marrow; BMD, bone marrow–derived; CM, conditioned medium; IL, interleukin; KO, knockout; M-CSF, macrophage colony-stimulating factor; MMP, matrix metalloproteinase; PB, peripheral blood; PBD, peripheral blood–derived; TAM, tumor-associated macrop
Anti-angiogenic effects of lycopene through immunomodualtion of cytokine secretion in human peripheral blood mononuclear cells ★
Keywords: CM، شرایط محیطی; APC, antigen-presenting cells; BC, β-carotene; CM, conditioned medium; DE, dexamethasone; EC, endothelial cell; ECGS, endothelial cell growth supplement; ELISA, enzyme-linked immunosorbent assay; FBS, fetal bovine serum; HUVECs, human umbilical vein endot
PDT-induced HSP70 externalization up-regulates NO production via TLR2 signal pathway in macrophages
Keywords: CM، شرایط محیطی; AC, apoptotic cell; CFP, cyan fluorescent protein; CM, conditioned medium; Cyt B, cytochalasin B; DN MyD88, dominant negative myeloid differentiation factor-88; DN TLR2, dominant negative TLR2; FRET, fluorescence resonance energy transfer; GFP, green fluo
Mitigation of radiation injury by selective stimulation of the LPA2 receptor
Keywords: CM، شرایط محیطی; Akt, protein kinase B; Bax, Bcl-2-associated X protein; Bcl-XL, B-cell lymphoma XL; BSA, bovine serum albumin; CM, conditioned medium; Cs, Cesium; Ct, threshold cycle value; DMEM, Dulbeco's modified Eagle medium; DMSO, dimethyl sulfoxide; DlgA, Drosophila
The protein pheromone Er-1 of the ciliate Euplotes raikovi stimulates human T-cell activity: Involvement of interleukin-2 system
Keywords: CM، شرایط محیطی; BrdU, 5-Bromo-2′deoxyuridine; CCL, chemokine (C–C motif) ligand; CFSE, carboxyfluorescein succinimidyl ester; CM, conditioned medium; DMEM, Dulbecco′s Modified Eagle′s Medium; DMSO, dimethyl sulfoxide; ERK1/2, extracellular signal-regulated kinase 1/2; FB
Neurotoxins released from interferon-gamma-stimulated human astrocytes
Keywords: CM، شرایط محیطی; AD, Alzheimer disease; cDNA, complementary DNA; CM, conditioned medium; COX, cyclooxygenase; DMEM, Dulbecco’s-modified Eagle’s medium; DPI, diphenylene iodonium; EDTA, ethylene diamine tetra-acetic acid; EGTA, ethylene glycol tetraacetic acid; FBS, fetal
Pasteurella multocida toxin (PMT) upregulates CTGF which leads to mTORC1 activation in Swiss 3T3 cells
Keywords: CM، شرایط محیطی; CM, conditioned medium; CCN, a family of cysteine rich matricellular proteins including CTGF, Cyr61 and Nov; GPCR, G-protein coupled receptor; mTORC1, mammalian target of rapamycin complex 1; PMT, Pasteurella multocida toxin; S6K1, ribosomal S6 kinase; DA
Loss of the Prader–Willi obesity syndrome protein necdin promotes adipogenesis
Keywords: CM، شرایط محیطی; CM, conditioned medium; Dkk, Dickkopf; Irs, insulin receptor substrate; MAGE, melanoma antigen gene; MDI, isobutylmethylxanthine, dexamethasone, and insulin; MEFs, mouse embryonic fibroblasts; PWS, Prader–Willi syndromeGenetic obesity; Mouse embryonic fib
Identification and characterization of canine growth differentiation factor-9 and its splicing variant
Keywords: CM، شرایط محیطی; ALK, activin receptor-like kinase; BLAST, basic local alignment search tool; BMP, bone morphogenetic protein; CM, conditioned medium; COX, cyclooxygenase; DIG, digoxigenin; FSH, follicle stimulating hormone; GDF, growth differentiation factor; HAS, hyalur
Rapamycin inhibits osteolysis and improves survival in a model of experimental bone metastases
Keywords: CM، شرایط محیطی; Bone metastases; Breast cancer; Osteoclast; mTOR; RapamycinαMEM, Alpha Modification of Eagle Medium; CM, conditioned medium; DMEM, Dulbecco Modified Eagle Medium; mTOR, mammalian Target of Rapamycin; RANKL, Receptor Activator of Nuclear factor κB Ligand;
Secretion of IL-6 and IL-8 from lysophosphatidic acid-stimulated oral squamous cell carcinoma promotes osteoclastogenesis and bone resorption
Keywords: CM، شرایط محیطی; LPA, lysophosphatidic acid; OSCC, oral squamous cell carcinoma; RANKL, receptor activator of nuclear factor (NF)-κB ligand; CM, conditioned medium; TRAP, tartrate-resistant acid phosphataseLysophosphatidic acid; IL-6; IL-8; Osteoclastogenesis; Oral squamo
Amyloid precursor protein (APP) regulates synaptic structure and function
Keywords: CM، شرایط محیطی; AD, Alzheimer's disease; APP, amyloid precursor protein; eGFP, enhanced green fluorescent protein; LTP, long-term potentiation; PPF, paired-pulse facilitation; CM, conditioned medium; PBS, phosphate-buffered saline; fEPSP, excitatory postsynaptic potentia
Laminin-511 expression is associated with the functionality of feeder cells in human embryonic stem cell culture
Keywords: CM، شرایط محیطی; hESC, human embryonic stem cell; ECM, extracellular matrix; HS, human serum; hFF, human foreskin fibroblast; hDF, human dermal fibroblast; mEF, mouse embryonic fibroblast; FBS, fetal bovine serum; GMP, good manufacturing practice; CM, conditioned medium;
In-depth analysis of the secretome identifies three major independent secretory pathways in differentiating human myoblasts
Keywords: CM، شرایط محیطی; CM, Conditioned medium; ECM, Extracellular matrix; MP, Microparticle; MV, Microvesicle; MVE, Multivesicular endosomeSkeletal muscle; Myoblast differentiation; Secretome; Proteomics; Secreted factors; Secreted membrane microvesicles
Pure populations of murine macrophages from cultured embryonic stem cells. Application to studies of chemotaxis and apoptotic cell clearance
Keywords: CM، شرایط محیطی; BMDM, bone marrow-derived macrophages; CM, conditioned medium; DC, dendritic cell; EB, embryoid bodies; EBV, Epstein–Barr virus; ESC, embryonic stem cell; ESDM, embryonic stem cell-derived macrophages; LIF, leukaemia inhibitory factorEmbryonic stem cells;
Modified Si-Miao-San extract inhibits inflammatory response and modulates insulin sensitivity in hepatocytes through an IKKβ/IRS-1/Akt-dependent pathway
Keywords: CM، شرایط محیطی; Akt, protien kinase B (PKB); BSA, bovine serum albumin; CM, conditioned medium; FFAs, free fatty acids; IKKβ, inhibitor of NF-κB kinase-β; IRS-1, insulin receptor substrates-1; mSMS, modified Si-Miao-San; NF-κB, nuclear factor-kappa B; PA, palmitate; TG,
Toll-like receptor cross-talk in human monocytes regulates CC-chemokine production, antigen uptake and immune cell recruitment
Keywords: CM، شرایط محیطی; APC, antigen-presenting cell; CM, conditioned medium; DC, dendritic cell; LPS, lipopolysaccharide; MDDC, monocyte-derived dendritic cell; PAMP, pathogen-associated molecular pattern; PRR, pattern recognition receptor; PBMC, peripheral blood mononuclear ce
Collection of in vivo-like liver cell secretome with alternative sample enrichment method using a hollow fiber bioreactor culture system combined with tangential flow filtration for secretomics analysis
Keywords: CM، شرایط محیطی; CM, conditioned medium; GPC3, glypican-3; HCC, hepatocellular carcinoma; HFB, hollow fiber bioreactor; HPRD, human protein reference database; LDH, lactate dehydrogenase; TFF, tangential flow filtrationHepG2; Hollow fiber bioreactor; LC–MS/MS; Proteome; S
Breast cancer cells inhibit spontaneous and bisphosphonate-induced osteoclast apoptosis
Keywords: CM، شرایط محیطی; αMEM, Alpha Modification of Eagle Medium; BIM, BCL-2-interacting mediator of cell death; CM, conditioned medium; DMEM, Dulbecco Modified Eagle Medium; EDTA, ethylene diamine tetra acetic acid; ERK, extracellular signal-regulated kinase; FITC, fluorescein
Accumulation of neurons differentiated from mouse embryonic stem cells in particular areas of culture plate surface
Keywords: CM، شرایط محیطی; BSA, bovine serum albumin; CM, conditioned medium; DRG, dorsal root ganglion; ES, embryonic stem; FITC, fluorescein isothiocyanate; NGF, nerve growth factor; PBS, phosphate-buffered saline.ES cell; Accumulation; Neuron; NGF-coated nanoscale magnetic bead
SERPINE2 is a possible candidate promotor for lymph node metastasis in testicular cancer
Keywords: CM، شرایط محیطی; Testicular germ cell tumor; Metastasis; SERPINE2; Secreted protein; XenograftTGCT, testicular germ cell tumor; CM, conditioned medium
Microvesicle Induction of Prostate Specific Gene Expression in Normal Human Bone Marrow Cells
Keywords: CM، شرایط محیطی; prostate; prostatic neoplasms; phenotype; bone marrow; gene expressionBM, bone marrow; CFSE, carboxyfluorescein diacetate succinimidyl ester; CM, conditioned medium; CT, cycle threshold; DAPI, 4,6-diamidino-2-phenylindole; EBV, Epstein Barr virus; FITC, f
Inactivation of insulin-like-growth factors diminished the anabolic effects of pregnancy-associated plasma protein-A (PAPP-A) on bone in mice
Keywords: CM، شرایط محیطی; BMD, bone mineral density; CM, conditioned medium; DEXA, dual energy X-ray absorptiometry; DMEM, Dulbecco’s modified Eagle’s medium; FCS, fetal calf serum; His, histidine; IGF, insulin-like-growth factor; IGFBP, IGF binding protein; KO, knockout; OB, oste
Enhanced mitochondrial biogenesis contributes to Wnt induced osteoblastic differentiation of C3H10T1/2 cells
Keywords: CM، شرایط محیطی; ALP, alkaline phosphatase; CM, conditioned medium; DCF, dichlorofluorescein; DMEM, Dulbecco's Modified Eagle Medium; FBS, fetal bovine serum; GSK-3β, glycogen synthase kinase-3β; mtDNA, mitochondrial DNA; Tfam, mitochondrial transcription factor A; NAO, n
Iron-mediated oxidative stress plays an essential role in ferritin-induced cell death
Keywords: CM، شرایط محیطی; CM, conditioned medium; DAPI, 4′,6-diamidino-2-phenylindole; DFO, desferrioxamine mesylate; EGF, epidermal growth factor; FER-CM, ferritin purified from CM collected after 3 h of primary rat hepatocyte culture; FER-T, commercially available ferritin prepa
Transplantation of magnetically labeled mesenchymal stem cells in a model of perinatal brain injury
Keywords: CM، شرایط محیطی; DAPI, 4′,6-diamidino-2-phenylindole; BrdU, 5-bromo-2′-deoxyuridine; CNS, central nervous system; CM, conditioned medium; CC, corpus callosum; CC/AC, corpus callosum and anterior commissure; DG, dragon green; FCS, fetal calf serum; FITC, fluorescein isothi
Isolation and characterization of a large soluble form of fibronectin that stimulates adhesion, spreading, and alignment of mouse erythroleukemia cells
Keywords: CM، شرایط محیطی; Ab, antibody; AF, adhesion factor; APRT, adenine phosphoribosyl transferase; cFN, cellular FN; CM, conditioned medium; D-MEM, Dulbecco's minimal essential medium; EDTA, ethylene diaminetetraacetic acid; EGTA, ethylene glycol-bis(2-aminoethylether)-N,N,N′N
Induction of mitotic S-phase of host and neighboring cells by Toxoplasma gondii enhances parasite invasion
Keywords: CM، شرایط محیطی; HFF, human foreskin fibroblast; CM, conditioned medium; BrdU, bromodeoxyuridine; PSFs, parasite secreted factors; MNP, mean number of parasitesToxoplasma; Invasion; Cell cycle; S-phase; BrdU
Anti-angiogenic effects and mechanisms of polysaccharides from Antrodia cinnamomea with different molecular weights
Keywords: CM، شرایط محیطی; CAM, chorioallantoic membrane; CM, conditioned medium; HL-60, human leukemia cells; HUVECs, human umbilical vein endothelial cells; IFN-γ, interferon-γ; IL-12, interleukin-12; MNC, mononuclear cells; PMAC, polysaccharides from mycelia of Antrodia cinnamom
Orphan nuclear receptor Nurr1 induces neuron differentiation from embryonic cortical precursor cells via an extrinsic paracrine mechanism
Keywords: CM، شرایط محیطی; BDNF, brain-derived neurotrophic factor; CM, conditioned medium; CNTF, ciliary neurotrophic factor; GDNF, glial cell line-derived neurotrophic factor; GFAP, glial fibrillary acidic protein; MAP2, microtubule-associated protein 2; LIF, leukemia inhibitory
Differential proteomic analysis of soluble extracellular proteins reveals the cysteine protease and cystatin involved in suspension-cultured cell proliferation in rice
Keywords: CM، شرایط محیطی; CBB, Coomassie Brilliant Blue; CM, conditioned medium; 2-DE, two-dimensional electrophoresis; ECM, extracellular matrix; IEF, isoelectric focusing; PSK, phytosulfokine; PVDF, polyvinylidene difluorideCell proliferation; Cystatin; Cysteine protease; Solubl
Signaling factors for irradiated glioma cells induced bystander responses in fibroblasts
Keywords: CM، شرایط محیطی; MN, micronucleus; TGF-β1, transforming growth factor-β1; AG, aminoguanidine; DEANO, diethylamine nitric oxide; NO, nitric oxide; iNOS, inducible NO synthase; ROS, reactive oxygen species; CM, conditioned medium; RIBE, radiation-induced bystander effectMic
R-spondin1 synergizes with Wnt3A in inducing osteoblast differentiation and osteoprotegerin expression
Keywords: CM، شرایط محیطی; ALP, alkaline phosphatase; CM, conditioned medium; Dkk1, Dickkopf-1; LRP6, low density lipoprotein receptor-related protein 6; OCN, osteocalcin; OPG, osteoprotegerin; Rspo1, R-spondin 1; RANKL, receptor activator of NF-kappaB ligandR-spondin1; Wnt3A; Wnt
Tumor anti-angiogenic effect and mechanism of action of δ-tocotrienol
Keywords: CM، شرایط محیطی; ASK-1, apoptosis signal-regulating kinase; CM, conditioned medium; DAB, 3,3′-diaminobenzidine; DCDHF, 2,7-dichlorodihydrofluorescein; DHF, 2,7-dichlorofluorescein; DLD-1, human colorectal adenocarcinoma cells; EGF, epidermal growth factor; eNOS, endotheli