Mechanistic studies of sodium pump
Keywords: تغییر کنفورماسیونی; Na,K-ATPase; Sodium pump; Active ion transport; Phosphoryl group transfer; Conformational change; Reaction mechanism
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Reversible inactivation of cytochrome P450 by alkaline earth metal ions: Auxiliary metal ion induced conformation change and formation of inactive P420 species in CYP101
Keywords: تغییر کنفورماسیونی; Cytochrome P450cam; Auxiliary metal ion; Alkaline-earth metal ion; Circular dichroism; Conformational change; Site-directed mutagenesis; Heme; P420
Energetics of binding and protein unfolding upon amphiphilic drug complexation with a globular protein in different aqueous media
Keywords: تغییر کنفورماسیونی; Myoglobin; Phenothiazine drug; Complexation; Energetics; Conformational change
Analysis of residues near the fusion peptide in the influenza hemagglutinin structure for roles in triggering membrane fusion
Keywords: تغییر کنفورماسیونی; Influenza; Hemagglutinin; Membrane fusion; Fusion peptide; HA structure; Conformational change
Quantitative effects of allosteric ligands and mutations on conformational equilibria in Salmonella typhimurium tryptophan synthase
Keywords: تغییر کنفورماسیونی; Allosteric; Conformational change; Hydrostatic pressure;
Mutation in the SH1 helix reduces the activation energy of the ATP-induced conformational transition of myosin
Keywords: تغییر کنفورماسیونی; Myosin; Motor domain; SH1 helix; Conformational change; Activation energy; Green fluorescent protein; Fluorescence resonance energy transfer;
Urea-induced Inactivation and Unfolding of Recombinant Phospholipid Hydroperoxide Glutathione Peroxidase from Oryza sativa
Keywords: تغییر کنفورماسیونی; Keywords Circular dichroism; Fluorescence; Conformational change; Phospholipid hydroperoxide glutathione peroxidase (PHGPx); Urea titration;
Direct Visualization of KirBac3.1 Potassium Channel Gating by Atomic Force Microscopy
Keywords: تغییر کنفورماسیونی; AFM, atomic force microscopy; EM, electron microscopy; 2D, two-dimensionalatomic force microscopy; channel gating mechanism; conformational change; ligand binding; potassium channel
Optical probes to identify the glucocorticoid receptor ligands in living cells
Keywords: تغییر کنفورماسیونی; Glucocorticoids; Glucocorticoid receptor; Coregulators; Conformational change; Fluorescence resonance energy transfer;
Solvent as a competitive inhibitor for Candida antarctica lipase B
Keywords: تغییر کنفورماسیونی; Kinetics; Organic solvent; Molecular modeling; Solid/gas biocatalysis; Conformational change; Solubility
A fluorescent indicator to visualize ligand-induced receptor/coactivator interactions for screening of peroxisome proliferator-activated receptor γ ligands in living cells
Keywords: تغییر کنفورماسیونی; Peroxisome proliferator-activated receptor γ; Conformational change; Coactivator; Agonist; Antagonist; Fluorescence resonance energy-transfer
Interaction of brilliant red X-3B with bovine serum albumin and application to protein assay
Keywords: تغییر کنفورماسیونی; Brilliant red X-3B; Bovine serum albumin; Non-covalent binding; Conformational change; Molecular spectrometry; Protein assay;
Three hydrolases and a transferase: Comparative analysis of active-site dynamics via the BioSimGrid database
Keywords: تغییر کنفورماسیونی; Biomolecular simulation; Database; Data mining; Molecular dynamics; Catalytic triad; Conformational change
Picogram detection of metal ions by melanin-sensitized piezoelectric sensor
Keywords: تغییر کنفورماسیونی; Quartz crystal microbalance; Melanin; Heavy metal; Conformational change; Circular dichroism; Infrared spectroscopy
Spectroscopic studies on the interaction between human hemoglobin and CdS quantum dots
Keywords: تغییر کنفورماسیونی; Hemoglobin; CdS quantum dots; Binding constant; Conformational change; Thermodynamic parameters; Fluorescence spectroscopy; CD spectroscopy; Raman spectroscopy;
Molecular Mechanisms of Cyclic Nucleotide-Gated Ion Channel Gating
Keywords: تغییر کنفورماسیونی; cyclic nucleotide-gated ion channel (CNG); conformational change; gating
Displaying 3D data on RNA secondary structures: coloRNA
Keywords: تغییر کنفورماسیونی; Display program; Visualization software; Three-dimensional structure; Conformational change; Tertiary fold; RMSD
C-terminal effect of Thermoanaerobacter tengcongensis ribosome recycling factor on its activity and conformation changes
Keywords: تغییر کنفورماسیونی; C-terminal effect; Ribosome recycling factor activity; Conformational change; ANS binding fluorescence; Thermoanaerobacter tengcongensis; Escherichia coli
Conformational Transitions of Adenylate Kinase: Switching by Cracking
Keywords: تغییر کنفورماسیونی; conformational change; energy landscape theory; cracking; strain
G protein coupled receptor structure and activation
Keywords: تغییر کنفورماسیونی; β2AR, beta 2 adrenoceptor; GPCR, G protein coupled receptor; TM, transmembraneGPCR; 7TM; Structure; Conformational change; Efficacy
Monitoring of conformational change in maltose binding protein using split green fluorescent protein
Keywords: تغییر کنفورماسیونی; Maltose binding protein; Green fluorescent protein; Conformational change
A complementary microscopy analysis of Sticholysin II crystals on lipid films: Atomic force and transmission electron characterizations
Keywords: تغییر کنفورماسیونی; StnII; Sticholysin II; EqtII; Equinatoxin II; PFPs; pore-forming proteins; AFM; atomic force microscopy; TEM; transmission electron microscopy; Actinoporin; Atomic force; Conformational change; Lipid films; Protein structure; Transmission electron microsc
Enzyme conformational dynamics during catalysis and in the ‘resting state’ monitored by hydrogen/deuterium exchange mass spectrometry
Keywords: تغییر کنفورماسیونی; Steady-state; Carboxypeptidase B; Lysozyme; Conformational change; Induced fit
FRET-based monitoring of conformational change of the β2 adrenergic receptor in living cells
Keywords: تغییر کنفورماسیونی; G protein-coupled receptor; β2 Adrenergic receptor; Fluorescence imaging; Conformational change; Agonist; Fluorescence resonance energy transfer; FlAsH; Cyan fluorescent protein
Change in conformation upon complexation of double-armed terephthalamide hosts: dynamic molecular recognition of ditopic guests with strong CD signaling
Keywords: تغییر کنفورماسیونی; Dynamic molecular recognition; Host-guest complex; Hydrogen bond; Circular dichroism; Exotopic receptor; Terephthalamide; tert-Amide; Conformational change; Helicity; Chirality;
Conformational changes and S1 â S0 origin transition energies: Polychlorinated biphenyls (PCBs)
Keywords: تغییر کنفورماسیونی; Ab initio MO calculation; PCB; Conformational change; Electronic spectrum; Electron correlation energy; Additivity rule;
Identification of critical arginine residues in the functioning of Rubisco activase
Keywords: تغییر کنفورماسیونی; ATP binding/hydrolysis; Arginine finger; AAA+ protein; Conformational change; Oligomerization
Time-resolved molecular dynamics of bacteriophage HK97 capsid maturation interpreted by electron cryo-microscopy and X-ray crystallography
Keywords: تغییر کنفورماسیونی; X-ray crystallography; Cryo-electron microscopy; Molecular movie; HK97 bacteriophage; Capsid expansion; Molecular machine; Conformational change
Probing conformations of the β subunit of F0F1-ATP synthase in catalysis
Keywords: تغییر کنفورماسیونی; F0F1; ATP synthase; F1-ATPase; Conformational change; Rotation; Motor protein
Targeted molecular dynamics simulation studies of calcium binding and conformational change in the C-terminal half of gelsolin
Keywords: تغییر کنفورماسیونی; Gelsolin C-terminal half; Calcium binding; Conformational change; Targeted molecular dynamics simulation
Bead-like passage of chloride ions through ClC chloride channels
Keywords: تغییر کنفورماسیونی; ClC channels; Chloride channels; Molecular dynamics; Conformational change; Selectivity filter; Ion permeation;
A Flexible Loop in Tyrosine Hydroxylase Controls Coupling of Amino Acid Hydroxylation to Tetrahydropterin Oxidation
Keywords: تغییر کنفورماسیونی; tyrosine hydroxylase; conformational change; iron-oxygen chemistry; substrate specificity; alanine scanningTyrH, tyrosine hydroxylase; PheH, phenylalanine hydroxylase; DTPA, diethylenetriaminepentaacetate; 6-MePH4, 6-methyltetrahydropterin; BH4, tetrahydr
Significance of the extra C-terminal tail of CaLP, a novel calmodulin-like protein involved in oyster calcium metabolism
Keywords: تغییر کنفورماسیونی; Extra C-terminal tail; Calmodulin-like protein; Ca2+/Mg2+; Conformational change; Target interaction; Calcium metabolism; Pearl oyster; Pinctada fucata
Checking the conformational stability of cystatin C and its L68Q variant by molecular dynamics studies: Why is the L68Q variant amyloidogenic?
Keywords: تغییر کنفورماسیونی; Human cystatin C; Molecular dynamics simulation; Conformational change; Amyloidosis; Single-point mutation
Responses of enantioselective characteristics of imidazolinone herbicides and Chiralcel OJ column to temperature variations
Keywords: تغییر کنفورماسیونی; Imidazolinone herbicides; Chiralcel OJ column; Temperature effects; Cyclic van’t Hoff plots; Step-temperature program; Conformational change
Electron transfer between cofactors in protein domains linked by a flexible tether
Keywords: تغییر کنفورماسیونی; Tethered protein; Electron transfer; Conformational change; Diffusion controlled electron transfer; Sulfite oxidase; Cytochrome bc1 complex;
Structural Evidence for Adaptive Ligand Binding of Glycolipid Transfer Protein
Keywords: تغییر کنفورماسیونی; crystal structure; homology modeling; conformational change; cavity; fluorescenceGLTP, glycolipid transfer protein; rGLTP, recombinant GLTP; MIR, multiple isomorphous replacement; NEM, N-ethylmaleimide
Evidence that Membrane Insertion of the Cytosolic Domain of Bcl-xL is Governed by an Electrostatic Mechanism
Keywords: تغییر کنفورماسیونی; apoptosis; Bcl-2 family; conformational change; membrane insertion; protein–membrane interactionsDOPG, dioleoyl phosphatidyl glycerol; DOPE, dioleoyl phosphatidyl ethanolamine; DOPC, dioleoyl phosphatidyl choline; TBPC, 1,2-distearoyl-9,10-dibromo-SN-glyc
Structural Snapshots of β-1,4-Galactosyltransferase-I Along the Kinetic Pathway
Keywords: تغییر کنفورماسیونی; β-1,4-galactosyltransferase; conformational change; structural snapshots; catalytic intermediates; role of conserved water moleculeGal-T1, β1,4-galactosyltransferase-1; GlcNAc, N-acetylglucosamine; α-LA, α-lactalbumin; Glc, glucose; LS, lactose synthase
Conformational changes and activity alterations induced by nickel ion in horseradish peroxidase
Keywords: تغییر کنفورماسیونی; Horseradish peroxidase; Nickel ion; Conformational change; Circular dichroism; Enzymatic activity
A mutant fusion (F) protein of simian virus 5 induces hemagglutinin-neuraminidase-independent syncytium formation despite the internalization of the F protein
Keywords: تغییر کنفورماسیونی; Simian virus 5; Fusion protein; Conformational change; Endocytosis; Syncytium formation
Going through the motions: The ATPase cycle of p97
Keywords: تغییر کنفورماسیونی; p97; AAA ATPase; Conformational change; Mechanism; SAXS; X-ray crystallography; Electron microscopy
Activity and structural changes of mushroom tyrosinase induced by n-alkyl sulfates
Keywords: تغییر کنفورماسیونی; Mushroom tyrosinase; n-Alkyl sulfates; Activation; Circular dichroism; Fluorescence; Conformational change;
Redox regulation of protein-tyrosine phosphatases
Keywords: تغییر کنفورماسیونی; Protein-tyrosine phosphatase; Regulation; Oxidation; Redox; Conformational change; Dimerization;
Titration of E. coli transhydrogenase domain III with bound NADP+ or NADPH studied by NMR reveals no pH-dependent conformational change in the physiological pH range
Keywords: تغییر کنفورماسیونی; Proton-translocating transhydrogenase; NADP(H); pH-titration; NMR; Domain III; Conformational change;
Detection of Bax protein conformational change using a surface plasmon resonance imaging-based antibody chip
Keywords: تغییر کنفورماسیونی; SPR imaging; Conformational change; Bax; TRAIL; SPR sensor;
Confinement and crowding effects on tryptophan synthase α2β2 complex
Keywords: تغییر کنفورماسیونی; TS, tryptophan synthase; PLP, pyridoxal 5′-phosphate; BTP, bis-tris propane; GP, α-d-glycerol-3-phosphatePyridoxal 5′-phosphate-dependent enzyme; Conformational change; Silica gel; Crowding; Confinement
Crystal structure of a mutant elongation factor G trapped with a GTP analogue
Keywords: تغییر کنفورماسیونی; EF-TU, elongation factor Tu; EF-G, elongation factor G; aa-tRNA, aminoacyl-tRNA; SAXS, small angle X-ray scattering; cryo-EM, cryo-electron microscopyTranslation; Protein synthesis; Elongation factor G; Translocation; Conformational change; GDPNP complex
Binding properties and conformational change of human growth hormone upon interaction with Fe3+
Keywords: تغییر کنفورماسیونی; Human growth hormone (hGH); Fe3+; Conformational change; Metal binding; Isothermal titration calorimetry (ITC); Differential scanning calorimetry (DSC);
Crucial role of the lipid part of lipopolysaccharide for conformational change of minor spike H protein of bacteriophage ÏX174
Keywords: تغییر کنفورماسیونی; Bacteriophage ÏX174; Minor spike H protein; Lipopolysaccharide; Host-recognition; Conformational change; Phage infection;