Keywords: کنونوکسین ها; Peptide toxins; Conotoxins; Cyclotides; Disulfide mimics; Chemical synthesis;
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Keywords: کنونوکسین ها; Venomics; Proteomics; Transcriptomics; Conotoxins; Venom peptides
Keywords: کنونوکسین ها; Conotoxins; Peptides; Cyclic peptides; Regulation; Select agents;
Mass spectrometric identification of bromotryptophan containing conotoxin sequences from the venom of C. amadis
Keywords: کنونوکسین ها; Conus venom; Conotoxins; Transcriptome; Mass spectrometry and bromotryptophan;
Glycine-rich conotoxins from the Virgiconus clade
Keywords: کنونوکسین ها; Conotoxins; O1 superfamily; Virgiconus
A new subfamily of conotoxins belonging to the A-superfamily
Keywords: کنونوکسین ها; Conotoxins; A-superfamily; Cysteine framework 14; Nicotinic acetylcholine receptors;
Molecular simulation study of the unbinding of α-conotoxin [Ï4E]GID at the α7 and α4β2 neuronal nicotinic acetylcholine receptors
Keywords: کنونوکسین ها; Conotoxins; Nicotinic acetylcholine receptors; Molecular-dynamics simulations; Binding-free energy; Antagonist; Umbrella-sampling;
Conotoxin truncation as a post-translational modification to increase the pharmacological diversity within the milked venom of Conus magus
Keywords: کنونوکسین ها; Conotoxins; N-terminal modification; Milked venom; Post-translational modification; α-Conotoxin; Mass spectrometry; API; Atmospheric pressure ionization; Arg(Pbf); N-alpha-9-fluorenylmethoxycarbonyl-N-g-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl-l
Characterization of the peptidylglycine α-amidating monooxygenase (PAM) from the venom ducts of neogastropods, Conus bullatus and Conus geographus
Keywords: کنونوکسین ها; Posttranslational modification; Conotoxins; Peptidylglycine α-amidating monooxygenase;
The three-dimensional solution structure of mini-M conotoxin BtIIIA reveals a disconnection between disulfide connectivity and peptide fold
Keywords: کنونوکسین ها; Conotoxins; Conpeptides; Structure
Towards an integrated venomics approach for accelerated conopeptide discovery
Keywords: کنونوکسین ها; Venomics; Conotoxins; Next generation sequencing; Mass spectrometry; Cone snails;
Recombinant expression and insecticidal properties of a Conus ventricosus conotoxin-GST fusion protein
Keywords: کنونوکسین ها; Conotoxins; Ion channels; Recombinant expression; Conus ventricosus; GST; glutathione-S-transferase; CTX; conotoxin;
Diversity and evolution of conotoxins in Conus virgo, Conus eburneus, Conus imperialis and Conus marmoreus from the South China Sea
Keywords: کنونوکسین ها; cDNA library; Transcripts; Conotoxins; Diversity; Evolution;
Cyclization of conotoxins to improve their biopharmaceutical properties
Keywords: کنونوکسین ها; Conotoxins; Cyclization; Cyclic peptides; Drug design; Cyclotides; Marine toxins
Large-scale discovery of conopeptides and conoproteins in the injectable venom of a fish-hunting cone snail using a combined proteomic and transcriptomic approach
Keywords: کنونوکسین ها; Conus venom; Peptidomics; Transcriptomics; Conopeptides; Conotoxins;
Cone snail milked venom dynamics - A quantitative study of Conus purpurascens
Keywords: کنونوکسین ها; Cone snail; Toxins; Conus purpurascens; Envenomation; Conotoxins; Conopeptides; Mass spectrometry; Milked venom; Peptide quantification; Amino acid analysis; Radula harpoon; aq.; aqueous; aq. TFA; Aqueous Trifluroacetic acid; Calc. MH+; Calculated Monoiso
Electrophysiological characterization of a novel small peptide from the venom of Conus californicus that targets voltage-gated neuronal Ca2+ channels
Keywords: کنونوکسین ها; Conus californicus; Conotoxins; Calcium channel; Electrophysiology; Xenopus laevis; Dorsal-root ganglion neurons;
Diversity of conotoxin types from Conus californicus reflects a diversity of prey types and a novel evolutionary history
Keywords: کنونوکسین ها; Conotoxins; C. californicus; Feeding diversity; cDNA library; RT-PCR; Signal peptides; Cys; cysteine; HPLC; high performance liquid chromatography; MALDI; matrix-assisted laser desorption/ionization; MS; mass spectrometry; PTM; posttranslational modificat
A novel approach for in vivo screening of toxins using the Drosophila Giant Fiber circuit
Keywords: کنونوکسین ها; Neuromodulation; Conotoxins; ImI; In vivo drug screening assay; Acetylcholine receptor antagonists; Neuronal circuit function; Electrophysiology; DrosophilaGF, Giant Fiber; DLM, Dorsal Longitudinal Muscle; TTM, Tergo Trochanteral Muscle; EJP, Excitatory J
New conopeptides of the D-superfamily selectively inhibiting neuronal nicotinic acetylcholine receptors
Keywords: کنونوکسین ها; Conus; Conotoxins; αD-conopeptide superfamily; Conus mustelinus; Conus capitaneus; Nicotinic acetylcholine receptor
Multiple genes elucidate the evolution of venomous snail-hunting Conus species
Keywords: کنونوکسین ها; COI; 16S rRNA; ITS2; 12S rRNA; Conidae; Conus; Molecular phylogeny; Molluscivorous; Piscivorous; Vermivorous; Conotoxins
Two new 4-Cys conotoxins (framework 14) of the vermivorous snail Conus austini from the Gulf of Mexico with activity in the central nervous system of mice
Keywords: کنونوکسین ها; Conoidea; Conidae; Cone snail; Conus austini; Conotoxins; Vermivorous; Worm-hunting; 4-Cys; Framework 14;
Voltage-gated ion channels and gating modifier toxins
Keywords: کنونوکسین ها; Sodium channel; Neurotoxins; Tetrodotoxin; Saxitoxin; Scorpion toxins; Anemone toxins; Batrachotoxin; Veratridine; Conotoxins; Toxin receptor sites; Insect toxins
Amino acid sequence and biological activity of a γ-conotoxin-like peptide from the worm-hunting snail Conus austini
Keywords: کنونوکسین ها; Conoidea; Conidae; Cone snail; Conus austini; Conotoxins; Vermivorous; Worm-hunting; γ-Conotoxin
Secondary structure formations of conotoxin genes: A possible role in mediating variability
Keywords: کنونوکسین ها; Secondary structures; Mutation; Conotoxins; Conservation; Variability
Clinico-toxinological characterization of the acute effects of the venom of the marine snail, Conus loroisii
Keywords: کنونوکسین ها; Conotoxins; Conus loroisii; Conus envenomation; Marine toxin
Biochemical and gene expression analyses of conotoxins in Conus textile venom ducts
Keywords: کنونوکسین ها; Conotoxins; Conus; Cone snails; Biosynthesis; Conotoxin gene expression; Venom duct;