دانلود مقالات ISI درباره COX-1، Cyclooxygenase-1 + ترجمه فارسی

آسیب کبد ناشی از استامینوفن: پیامدهای هوموتازی زمانی متابولیسم چربی و سیگنالینگ ایکوسانوئید

Acetaminophen-induced liver injury: Implications for temporal homeostasis of lipid metabolism and eicosanoid signaling pathway

Keywords: COX-1، Cyclooxygenase-1; Free fatty acids; Acetaminophen; Liver; Cyclooxygenase; EicosanoidsAPAP, acetaminophen; ELOVL, elongases; COX-1, cyclooxygenase-1; COX-2, cyclooxygenase-2; ALT, alanine aminotransferase; AST, aspartate aminotransferase; DAB, 3,3′-Diaminobenzidine; PBS, ph

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

استرس اکسیداتیو وابسته به سیکلوکوکسیژناز 2، باعث کاهش اختلال وابسته به اندوتلیوم در موش صحرایی موسوم به پالمیتات می شود

Cyclooxygenase-2-dependent oxidative stress mediates palmitate-induced impairment of endothelium-dependent relaxations in mouse arteries

Keywords: COX-1، Cyclooxygenase-1; ACh, acetylcholine; COX-1, cyclooxygenase-1; COX-2, cyclooxygenase-2; DHE, dihydroethidium; DMPO, 5,5-dimethyl-l-pyrroline-N-oxide; DTPA, diethylenetriaminepentaacetic acid; EDCFs, endothelium-derived contracting factors; EDR, endothelium-dependent relaxa

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Belamcanda chinensis (L.) DC-An ethnopharmacological, phytochemical and pharmacological review

Keywords: COX-1، Cyclooxygenase-1; AMPK, Adenosine 5′-Monophosphate-Activated Protein Kinase; COX-1, Cyclooxygenase-1; COX-2, Cyclooxygenase-2; Ca2+-ATPase, Calcium Pump; CPAE, Calf Pulmonary Arterial Endothelial; CCl4, Carbon Tetrachloride; DPPH, 1,1-Diphenyl-2-Picrylhydrazyl; ETOH, Ethan

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Liquid chromatography–tandem mass spectrometry for simultaneous measurement of thromboxane B2 and 12(S)-hydroxyeicosatetraenoic acid in serum

Keywords: COX-1، Cyclooxygenase-1; AA, arachidonic acid; COX-1, cyclooxygenase-1; TX, thromboxane; 12-LOX, 12-lipoxygenase; 12(S)-HETE, 12(S)-hydroxyeicosatetraenoic acid; SPE, solid-phase extraction; HHT, 12-l-hydroxy-5,8,10-hepta-decatrienoic acid; COX-2, cyclooxygenase-2; 12(S)-HpETE, 1

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

New direct and indirect methods for the detection of cyclooxygenase 1 acetylation by aspirin; the lack of aspirin resistance among healthy individuals

Keywords: COX-1، Cyclooxygenase-1; COX-1, cyclooxygenase-1; AA, arachidonic acid; TXA2, thromboxane A2; acCOX-1, acetylated COX-1; nacCOX-1, non-acetylated COX-1; PRP, Platelet rich plasma; PDP, Platelet depleted plasma; anti-nacCOX-1, antibody specific to non-acetylated COX-1; anti-acCOX-

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

High-dose aspirin in dogs increases vascular resistance with limited additional anti-platelet effect when combined with potent P2Y12 inhibition

Keywords: COX-1، Cyclooxygenase-1; COX-1, cyclooxygenase-1; TXA2, thromboxane A2; TXB2, thromboxane B2; ADP, adenosine diphosphate; TP, platelet thromboxane-prostanoid; PGI2, prostaglandin I2; CFR, cyclic flow reductions; TBV, total blood volume; MAP, mean aortic blood pressure; AA, arachi

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Embryonic exposure to PFOS induces immunosuppression in the fish larvae of marine medaka

Keywords: COX-1، Cyclooxygenase-1; CAT, Catalase; COX-1, Cyclooxygenase-1; COX-2, Cyclooxygenase-2; dpf, Days post fertilization; dph, Days post hatch; DMSO, Dimethyl sulfoxide; GPX, Glutathione peroxidase; IL-8, Interleukin-8; IL-1β, Interleukin-1 beta; LPS, Lipopolysaccharides; PFOS, Per

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Atropa acuminata Royle Ex Lindl. blunts production of pro-inflammatory mediators eicosanoids., leukotrienes, cytokines in vitro and in vivo models of acute inflammatory responses

Keywords: COX-1، Cyclooxygenase-1; AA, Arachidonic acid; COX-1, Cyclooxygenase-1; COX-2, Cyclooxygenase-2; AAEE, Ethanolic extract of Atropa acuminata; GPX, Glutathione peroxidase; GR, Glutathione reductase; g, Grams; H2O2, Hydrogen peroxide; iNOS, Inducible nitric oxide synthase; IL-6, In

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Gene therapy for the prevention of vein graft disease

Keywords: COX-1، Cyclooxygenase-1; Ad, adenovirus; AAV, adeno-associated virus; COX-1, cyclooxygenase-1; EC, endothelial cell; ECM, extracellular matrix; eNOS, endothelial nitric oxide synthase; HDAd, helper-dependent adenovirus; HVJ, hemagglutinating virus of Japan; IH, intimal hyperplasi

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2013 سفارش ترجمه

Novel selective COX-1 inhibitors suppress neuroinflammatory mediators in LPS-stimulated N13 microglial cells

Keywords: COX-1، Cyclooxygenase-1; AA, arachidonic acid; AD, Alzheimer's disease; ALS, amyotrophic lateral sclerosis; asa, aspirin; cel, celecoxib; CNS, central nervous system; COX-1, cyclooxygenase-1; COX-2, cyclooxygenase-2; eto, etoricoxib; HWBA, human whole blood assay; IκBα, inhibitor

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Semisynthesis and pharmacological investigation of lipo-alkaloids prepared from aconitine

Keywords: COX-1، Cyclooxygenase-1; COX-1, cyclooxygenase-1; COX-2, cyclooxygenase-2; LTB4, leukotriene B4Processed aconite roots; Lipo-alkaloids; COX-1; COX-2; LTB4

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Roles of prostaglandin E2 in the cochlea

Keywords: COX-1، Cyclooxygenase-1; AC, adenylyl cyclase; AA, arachidonic acid; cAMP, cyclic adenosine monophosphate; COX, cyclooxygenase; COX-1, cyclooxygenase-1; COX-2, cyclooxygenase-2; DAG, diacylglycerol; EP, E-prostanoid receptor; IP3, inositol-1,4,5-trisphosphate; MRP4, multidrug res

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Aspirin treatment influences platelet-related inflammatory biomarkers in healthy individuals but not in acute stroke patients

Keywords: COX-1، Cyclooxygenase-1; TRAP, thrombin receptor activating peptide; TxB2, thromboxane B2; ASA, acetylsalicylic acid; COX-1, cyclooxygenase-1; PerCp, peridinin chlorophyll protein; APC-Cy™7, allophycocyanin and cyanine 7; FITC, fluorescein isothiocyanate; PE, phycoerythrin; APC,

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

UVB light regulates expression of antioxidants and inflammatory mediators in human corneal epithelial cells

Keywords: COX-1، Cyclooxygenase-1; COX-1, cyclooxygenase-1; COX-2, cyclooxygenase-2; FLAP, 5-lipoxygenase activating protein; GST, glutathione S-transferase; mGST, microsomal GST; HO-1, heme oxygenase-1; LTA4 hydrolase, leukotriene A4 hydrolase; LTC4 synthase, leukotriene C4 synthase; LOX,

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Sulfur mustard analog, 2-chloroethyl ethyl sulfide-induced skin injury involves DNA damage and induction of inflammatory mediators, in part via oxidative stress, in SKH-1 hairless mouse skin

Keywords: COX-1، Cyclooxygenase-1; ATM, ataxia telangiectasia mutated; ATR, ataxia telangiectasia-Rad3-related; CEES, 2-chloroethyl ethyl sulfide; COX-1, cyclooxygenase-1; COX-2, cyclooxygenase-2; ECM, extra cellular matrix protein; eNOS, endothelial NOS; GSH, glutathione; iNOS, inducible

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Protective effect of Chrysanthemum indicum Linne against 1-methyl-4-phenylpridinium ion and lipopolysaccharide-induced cytotoxicity in cellular model of Parkinson’s disease

Keywords: COX-1، Cyclooxygenase-1; BCL2, B-cell CLL/lymphoma 2; BAX, BCL2-associated X protein; iNOS, inducible nitric oxide synthase; COX-1, cyclooxygenase-1; COX-2, cyclooxygenase-2; IL-1β, interleukin-1β; IL-6, interleukin-6; TNF-α, tissue necrosis factor-alpha; GAPDH, glyceraldehydes-3

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Reduced platelet response to aspirin in patients with coronary artery disease and type 2 diabetes mellitus

Keywords: COX-1، Cyclooxygenase-1; AA, Arachidonic acid; ARU, Aspirin reaction units; AUC, Area under the curve; CAD, Coronary artery disease; COX-1, Cyclooxygenase-1; DM, Diabetes mellitus; HbA1c, Haemoglobin A1c; MI, Myocardial infarction; TxA2, Thromboxane A2; TxB2, Thromboxane B2; sP-s

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Toll-like receptor 4 participates in gastric mucosal protection through Cox-2 and PGE2

Keywords: COX-1، Cyclooxygenase-1; TLR4, Toll-like receptor 4; Cox-1, cyclooxygenase-1; Cox-2, cyclooxygenase-2; PGE2, prostaglandin E2; ELISA, enzyme-linked immunosorbent assay; LPS, lipopolysaccharide; IF, immunofluorescent; PAMPs, pathogen-associated molecular patterns; DAMPs, damage-as

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Liquid chromatography/tandem mass spectrometry study of anti-inflammatory activity of Plantain (Plantago L.) species

Keywords: COX-1، Cyclooxygenase-1; 12-HETE, 12(S)-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoic acid; 12-HHT, 12(S)-hydroxy-(5Z,8E,10E)-heptadecatrienoic acid; 12-LOX, 12-lipoxygenase; COX-1, cyclooxygenase-1; COX-2, cyclooxygenase-2; MRM, multiple reaction monitoring; MS2SIM, single-stage mass

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Emergency Reversal of Antiplatelet Agents in Patients Presenting with an Intracranial Hemorrhage: A Clinical Review

Keywords: COX-1، Cyclooxygenase-1; Antiplatelet agent; Aspirin; Clopidogrel; Coagulopathy; Intracranial hemorrhage; Platelet transfusion; Stroke; TraumaASA, Aspirin (acetylsalicylic acid); COX-1, Cyclooxygenase-1; ICH, Intracranial hemorrhage; NSAIDs, Nonsteroidal anti-inflammatory drugs;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Role of MAP kinases in regulating expression of antioxidants and inflammatory mediators in mouse keratinocytes following exposure to the half mustard, 2-chloroethyl ethyl sulfide

Keywords: COX-1، Cyclooxygenase-1; CEES, 2-chloroethyl ethyl sulfide; COX-1, cyclooxygenase-1; COX-2, cyclooxygenase-2; GST, glutathione S-transferase; mGST, microsomal GST; LTA4, leukotriene A4; LTC4, leukotriene C4; 5-LOX, 5-lipoxygenase; FLAP, 5-LOX activating protein; 8-LOX, 8-lipoxyge

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Characterization of 4-methyl-2-oxo-1,2-dihydroquinolin-6-yl acetate as an effective antiplatelet agent

Keywords: COX-1، Cyclooxygenase-1; AA, arachidonic acid; AQ, acetoxy quinolone; CDNB, 1-cloro 2,4-dinitro benzene; Cox-1, cyclooxygenase-1; Cox-2, cyclooxygenase-2; CRTAase, calreticulin transacetylase; DAMC, 7,8-diacetoxy-4-methyl coumarin; DCFH-DA, dichlorofluorescin diacetate; NOS, nitr

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Ibuprofen-induced hypersensitivity syndrome

Keywords: COX-1، Cyclooxygenase-1; ADR, adverse drug reaction; AUC, area under the concentration-time curve; Cmax, maximum plasma concentration; CoA, coenzyme A; COX-1, cyclooxygenase-1; COX-2, cyclooxygenase-2; CYP, cytochrome P450; HSRs, hypersensitivity reactions; NSAID, nonsteroidal an

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2010 سفارش ترجمه

Anti-inflammatory effect of coumarins isolated from Corydalis heterocarpa in HT-29 human colon carcinoma cells

Keywords: COX-1، Cyclooxygenase-1; COX-1, cyclooxygenase-1; COX-2, cyclooxygenase-2; COX, cyclooxygenases; ELISA, enzyme-linked immunosorbent assay; eNOS, endothelial nitric oxide synthase; I-κB, inhibitor of kappa B; IKK, I kappaB kinase; IL-1 α,β, interleukin-1 α,β; IL-6, interleukin 6;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Platelet inhibition assessed with VerifyNow, flow cytometry and PlateletMapping in patients undergoing heart surgery

Keywords: COX-1، Cyclooxygenase-1; CABG, coronary artery bypass grafting; VASP, vasodilator-stimulated phosphoprotein; ADP, adenosine diphosphate; COX-1, cyclooxygenase-1; PRI, platelet reactivity index; TEG, thrombelastograph; ACT, activated clotting time; FITC, fluorescein isothiocyanate

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Cyclooxygenase-2 mediates hydrogen peroxide-induced wound repair in human endothelial cells

Keywords: COX-1، Cyclooxygenase-1; Cox-2, cyclooxygenase-2; Cox-1, cyclooxygenase-1; PGE2, prostaglandin E2; HUVEC, human umbilical vein endothelial cells; ROS, reactive oxygen species; eNOS, NO synthase; TNFα, tumor necrosis factor-α; TTFA, thenoyltrifluoroacetone; L-NAME, Nω-nitro-l-argi

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Multiple defects in negative regulation of the PKB/Akt pathway sensitise human cancer cells to the antiproliferative effect of non-steroidal anti-inflammatory drugs

Keywords: COX-1، Cyclooxygenase-1; Cdk2, cyclin-dependent kinase-2; COX-1, cyclooxygenase-1; COX-2, cyclooxygenase-2; Egr-1, early growth response-1; ERK, extracellular signal-regulated protein kinase; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; GDF-15, growth/differentiation factor-1

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2009 سفارش ترجمه

15-Deoxy-delta12,14-prostaglandin-J2 up-regulates cyclooxygenase-2 but inhibits prostaglandin-E2 production through a thiol antioxidant-sensitive mechanism

Keywords: COX-1، Cyclooxygenase-1; BSO, buthionine sulfoximine; COX, cyclooxygenase; COX-1, cyclooxygenase-1; COX-2, cyclooxygenase-2; DCFH-DA, 2′,7′-dichloro-fluorescein diacetate; DMSO, dimethyl sulfoxide; ERK1/2, extracellular-regulated 1/2 kinase; FBS, fetal bovine serum; GSH, reduced

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

COX-2 expression and function in the hyperalgesic response to paw inflammation in mice

Keywords: COX-1، Cyclooxygenase-1; NSAID, nonsteroidal anti-inflammatory drug; COX, cyclooxygenase; COX-1, cyclooxygenase-1; COX-2, cyclooxygenase-2; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; HPWL, hindpaw withdrawl latency; PGE2, prostaglandin E2; PGH2, prostaglandin H2; PGI2, pros

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Ceramide elevates 12-hydroxyeicosatetraenoic acid levels and upregulates 12-lipoxygenase in rat primary hippocampal cell cultures containing predominantly astrocytes

Keywords: COX-1، Cyclooxygenase-1; cPLA2, cytosolic phospholipase A2; COX-1, cyclooxygenase-1; COX-2, cyclooxygenase-2; Ddit3, DNA-damage inducible transcript, 3; DMEM, Dulbecco's Modified Eagle's Medium; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; 12-LOX, 12-lipoxygenase; 12-(S)-HETE

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

UVB light upregulates prostaglandin synthases and prostaglandin receptors in mouse keratinocytes

Keywords: COX-1، Cyclooxygenase-1; CRTH2, Chemoattractant receptor-homologous molecule expressed on T helper type 2 cells; COX-1, cyclooxygenase-1; COX-2, cyclooxygenase-2; cPLA2, cytosolic phospholipase A2; DAGL, diacylglycerol lipase; EETs, epoxyeicosatrienoic acids; HETEs, 19- and 20-hy

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

The anti-apoptotic MAP kinase pathway is inhibited in NIH3T3 fibroblasts with increased expression of phosphatidylinositol transfer protein β

Keywords: COX-1، Cyclooxygenase-1; PI-TP, phosphatidylinositol transfer protein; PI, phosphatidylinositol; PC, phosphatidylcholine; SM, sphingomyelin; PKC, protein kinase C; COX-1, cyclooxygenase-1; COX-2, cyclooxygenase-2; DMEM, Dulbecco's modified Eagle medium; CM, conditioned medium; NC

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Anti-inflammatory and gastrointestinal effects of a novel diclofenac derivative

Keywords: COX-1، Cyclooxygenase-1; ADT, anethole trithione; AP-1, activator protein-1; COX-1, cyclooxygenase-1; COX-2, cylcooxygenase-2; CBS, cystathionine β-synthetase; CSE, cystathionine γ-lyase; HO-1, heme oxygenase-1; IL-1β, interleukin-1β; IL-10, interleukin-10; LPS, lipopolysaccharid

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2007 سفارش ترجمه

Inhibition of COXs and 5-LOX and activation of PPARs by Australian Clematis species (Ranunculaceae)

Keywords: COX-1، Cyclooxygenase-1; ACN, acetonitrile; COX-1, cyclooxygenase-1; COX-2, cyclooxygenase-2; EtAc, ethyl acetate; 5-HETE, 5-hydroxyeicosatetraenoic acid; HepG2, human Caucasian hepatocyte carcinoma; HPLC, high-performance liquid chromatography; 5-LOX, 5-lipoxygenase; NSAIDs, non

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Selective induction of cyclooxygenase-2 plays a role in lysophosphatidic acid regulated Fas ligand cell surface presentation

Keywords: COX-1، Cyclooxygenase-1; Cox-2, cyclooxygenase-2; ASA, acetylsalicylic acid; NS-398 (NS), Cox-2 inhibitor; Cox-1, cyclooxygenase-1; FasL, Fas ligand; LPA, lysophosphatidic acid; sPLA2- IIA, type II secretory PLA2; GPCR, G-protein-coupled receptor; ERK, extracellular signal regula

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Aspirin therapy for inhibition of platelet reactivity in the presence of erythrocytes in patients with vascular disease

Keywords: COX-1، Cyclooxygenase-1; ADP, adenosine 5′-diphosphate; ANOVA, analysis of variance; ASA, acetylsalicylic acid; ATP, adenosine triphosphate; BID, twice-daily; 14C-5HT, 14C-serotonin; COX-1, cyclooxygenase-1; L, loading dose; OD, daily; PRP, platelet-rich plasma; PPP, platelet-poo

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

QSAR analysis of meclofenamic acid analogues as selective COX-2 inhibitors

Keywords: COX-1، Cyclooxygenase-1; COX-1, Cyclooxygenase-1; COX-2, Cyclooxygenase-2; MOE, molecular operating environment; QSAR, quantitative structure–activity relationshipCOX-1/COX-2/MOE/QSAR/meclofenamic acid analogues

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه