Down-regulation of aldo–keto reductase AKR1B10 gene expression by a phorbol ester via the ERK/c-Jun signaling pathway
Keywords: AKR, aldo–keto reductase; TPA, 12-O-tetradecanoyl phorbol 13-acetate; PKC, protein kinase C; cPKC, conventional PKC; nPKC, novel PKC; aPKC, atypical PKC; ERK, extracellular signal regulate kinase; SPAK/JNK, stress-activated kinase/c-Jun N-terminal kinaseA