دانلود مقالات ISI درباره CPT، camptothecin + ترجمه فارسی

پیامدهای پیشرفت های اخیر در داروهای تزریق دارویی هدفمند و کربوکسی متیل کیتوزان و برنامه های کاربردی مهندسی بافت

The implications of recent advances in carboxymethyl chitosan based targeted drug delivery and tissue engineering applications

Keywords: CPT، camptothecin; ADR, adriamycin; AQCOM, alginate-Q-CMCS-organic montmorillonite; bFGF, basic fibroblast growth gactor; BSA, bovine serum albumin; BMSCs, bone marrow stromal cells; CPT, camptothecin; CMC, critical micelle concentration; CMCS, carboxymethyl chitosan; O-CMC

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2014 سفارش ترجمه

Human topoisomerase IB is a target of a thiosemicarbazone copper(II) complex

Keywords: CPT، camptothecin; Human DNA topoisomerase IB; Thiosemicarbazone; Copper(II) complex; Catalytic inhibitor; Molecular docking; Cytotoxicitytopo IB, human topoisomerase IB; complex (1), [Cu(PyCT4BrPh)Cl]; CPT, camptothecin

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Combination treatment with Rhizoma Paridis and Rhizoma Curcuma longa extracts and 10-hydroxycamptothecin enhances the antitumor effect in H22 tumor model by increasing the plasma concentration

Keywords: CPT، camptothecin; HCPT, 10-hydroxycamptothecin; LH, prescription of Rhizoma Paridis and Rhizoma Curcuma longa; DJ, the part between duodenum and jejunum; F, permeation flux; Papp, apparent permeability; CPT, camptothecin; HPLC-FLD, high-performance liquid chromatography wi

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Synthesis and biological evaluation of quinazolin-4(3H)-one derivatives bearing dithiocarbamate side chain at C2-position as potential antitumor agents

Keywords: CPT، camptothecin; Quinazolin-4(3H)-one; Dithiocarbamate; Synthesis; Antiproliferative activity; G2/M arrest; Spindle assembly checkpoint5-FU, 5-fluorouracil; ATR, attenuated total reflection; BubR1, Bub1-related protein kinase; CPT, camptothecin; 7,8-DHF, 7,8-dihydrofolate

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Synthesis and biological evaluation of new fluorinated and chlorinated indenoisoquinoline topoisomerase I poisons

Keywords: CPT، camptothecin; CPT, camptothecin; Top1, topoisomerase IB; TDP1, tyrosyl-DNA phosphodiesterase 1; TDP2, tyrosyl-DNA phosphodiesterase 2; PAGE, polyacrylamide gel electrophoresis; SDS, sodium dodecyl sulfateTopoisomerase I; Indenoisoquinoline; Anticancer; Cytotoxicity; Ty

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

A Selective Small Molecule DNA2 Inhibitor for Sensitization of Human Cancer Cells to Chemotherapy

Keywords: CPT، camptothecin; BLM, Bloom Syndrome; CPT, camptothecin; DNA2, DNA2 nuclease/helicase; DSB, double-strand break; EMSA, electrophoretic mobility shift assay; EXO1, exonuclesae 1; FA, Fanconi anemia; FEN1, flap endonuclease 1; HDR, homology direct repair; HTS, high throughp

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

DNA repair defects ascribed to pby1 are caused by disruption of Holliday junction resolvase Mus81-Mms4

Keywords: CPT، camptothecin; YKO, yeast knockout; P body, cytoplasmic processing body; SSL, synthetic sick/syntheticlethal; SGD, Saccharomyces genome database; MMS, methyl methanesulfonate; HU, hydroxyurea; CPT, camptothecin; DRYGIN, data repository of yeast genetic interactionsSacch

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Mutation of Gly717Phe in human topoisomerase 1B has an effect on enzymatic function, reactivity to the camptothecin anticancer drug and on the linker domain orientation

Keywords: CPT، camptothecin; hTop1B, human topoisomerase 1B; CPT, camptothecin; TPT, topotecan; DMSO, dimethyl sulfoxide; EDTA, ethylenediaminetetraacetic acid; EGTA, ethylene glycol tetraacetic acid; DTT, dithiothreitol; BSA, bovine serine albumin; TBE, tris-borate-EDTA; PMSF, pheny

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Characterization of 9-nitrocamptothecin-in-cyclodextrin-in-liposomes modified with transferrin for the treating of tumor

Keywords: CPT، camptothecin; BCA, bicinchoninic acid; CD, cyclodextrin; CPT, camptothecin; DCL, drug-in-cyclodextrin-in-liposome; DSPC, 1,2-distearoyl-sn-glycero-3-phosphatidylcholine; DSPE-PEG2000, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-(carbonyl-methoxypolyethyleneglycol

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Distinct and overlapping functions of the cullin E3 ligase scaffolding proteins CUL4A and CUL4B

Keywords: CPT، camptothecin; 6-4PP, 6-4 photoproduct; BMC, bone marrow cell; Cdk, cyclin-dependent kinase; CPD, cyclopyrimidine dimer; CPT, camptothecin; CRBN, Cereblon; CRL4, cullin RING ligase; CS, Cockayne syndrome; CSN, COP9 signalosome; CUL4A, cullin 4A; CUL4B, cullin 4B; DCAF,

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Determination of irinotecan and its metabolite SN-38 in rabbit plasma and tumors using a validated method of tandem mass spectrometry coupled with liquid chromatography

Keywords: CPT، camptothecin; CPT, camptothecin; CPT-11, irinotecan; CV, coefficient of variation; IS, internal standard; LLE, liquid-liquid extraction; MRM, multiple reaction monitoring; SD, standard deviationIrinotecan; SN-38; Camptothecin; Rabbit; VX2 tumor; LC–MS/MS

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

UVA generated free radicals in irinotecan (CPT-11) in the presence of copper ions

Keywords: CPT، camptothecin; ACN, acetonitrile; CPT, camptothecin; CPT-11, irinotecan; DIPPMPO, 5-(diisopropoxy-phosphoryl)-5-methyl-1-pyrroline N-oxide; DPPH, 2,2-diphenyl-1-picrylhydrazyl; DMPO, 5,5-dimethyl-1-pyrroline N-oxide; DMSO, dimethylsulfoxide; DNA, deoxyribonucleic acid;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Nanotoxicology applied to solid lipid nanoparticles and nanostructured lipid carriers – A systematic review of in vitro data

Keywords: CPT، camptothecin; Chol, cholesterol; COM, Compritol™ 888 ATO; CP, cetyl palmitate; CPC, cetylpyrimidium chloride; CPT, camptothecin; CTAB, cetyltrimethylammonium bromide, hexadecyltrimethylammonium bromide; CysA, Cyclosporine A; DOPE, dioleoylphosphatidyl ethanolamine; DOT

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2014 سفارش ترجمه

Increased Cdc7 expression is a marker of oral squamous cell carcinoma and overexpression of Cdc7 contributes to the resistance to DNA-damaging agents

Keywords: CPT، camptothecin; DDK, Dbf4-dependent kinase; DDR, DNA damage response; OSCC, oral squamous cell carcinoma; IHC, immunohistochemistry; HU, hydroxyurea; CPT, camptothecin; CI, confidence interval; HR, hazard ratios; TUNEL, terminal deoxynucleotidyl transferase-mediated dUTP

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Oxo-heterocyclic fused naphthalimides as antitumor agents: Synthesis and biological evaluation

Keywords: CPT، camptothecin; Oxo-heterocyclic; Naphthalimides; Antitumor agents; Topo I; Topo II; DNA intercalationCD, circular dichroism; CPT, camptothecin; ctDNA, calf thymus DNA; kDNA, kinetoplast DNA; SAR, structure–activity relationship

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Evodiamine, a dual catalytic inhibitor of type I and II topoisomerases, exhibits enhanced inhibition against camptothecin resistant cells

Keywords: CPT، camptothecin; CPT, camptothecin; DMSO, dimethylsulphoxide; EtBr, ethidium bromide; m-AMSA, amsacrine; MTT, 3-(4,5-dimethyl thiazol-2yl)-2,5-diphemyltetrazolium bromide; Nck, nicked; Rel, relaxed; Sc, supercoiled; Topo I, topoisomerase I; Topo II, topoisomerase IIEvodia

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Alternatively spliced tissue factor and full-length tissue factor protect cardiomyocytes against TNF-α-induced apoptosis

Keywords: CPT، camptothecin; asTF, alternatively spliced TF; AV, annexin-V; Bad, Bcl-2-antagonist of cell death; Bax, Bcl-2-associated X; Bcl-2, B-cell lymphoma 2; Bcl-xL, B-cell lymphoma-extra large; CPT, Camptothecin; Clk, Cdc2-like kinases; cRGD, cyclic arginine–glycine–aspartate

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Genotoxic stress modulates CDC25C phosphatase alternative splicing in human breast cancer cell lines

Keywords: CPT، camptothecin; CDC25 phosphatases; Alternative splicing; Genotoxic stress; Breast cancer cellsATM, ataxia telangiectasia-mutated; ATR, ATM- and Rad3-related; CDC25, cell division cycle 25; CDK, cyclin-dependent kinase; CPT, camptothecin; DAPI, 4′,6-diamidino-2-phenylind

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Hypoxia modulates the effect of dihydroartemisinin on endothelial cells

Keywords: CPT، camptothecin; BSO, buthionine sulfoximine; CPT, camptothecin; DCF-DA, dihydrodichlorofluorescein diacetate; DeoxyDHA, dihydrodeoxyartemisinin; DHA, dihydroartemisinin; EC, endothelial cell; GSH, glutathione; HIF-1α, hypoxia inducible factor; HMEC-1, human microvascular

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Sodium salicylate is a novel catalytic inhibitor of human DNA topoisomerase II alpha

Keywords: CPT، camptothecin; 5-IDNR, 5-iminodaunorubicin; ASA, acetylsalicylic acid; ATM, ataxia telangiectasia mutated; COX-2, cyclooxygenase-2; CPT, camptothecin; DEM, diethyl maleate; DSB, double-stranded break; ICE, in vivo complex of enzyme; IR, ionizing radiation; kDNA, kinetop

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Role of senataxin in DNA damage and telomeric stability

Keywords: CPT، camptothecin; AOA, ataxia with oculomotor apraxia; ChIP, chromatin immunoprecipitation; CPT, camptothecin; LCLs, lymphoblastoid cell lines; MMC, mitomycin C; Q-FISH, quantitative-FISH; RT, room temperature; SETX, senataxinAOA2; SETX; Helicase domain; DNA damage; Telome

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Kinetic modelling of the role of the aldehyde dehydrogenase enzyme and the breast cancer resistance protein in drug resistance and transport

Keywords: CPT، camptothecin; Efflux pump; Drug kinetics; Topotecan; Aldehyde dehydrogenase; Structural identifiability; Parameter estimationALDH, aldehyde dehydrogenase; BRCP, breast cancer resistance protein; CPT, camptothecin; DNA, deoxyribonucleic acid; dsDNA, double-stranded DNA;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Phenylbutyrate inhibits homologous recombination induced by camptothecin and methyl methanesulfonate

Keywords: CPT، camptothecin; CPT, camptothecin; Top1, topoisomerase I; HDAC, histone deacetylase; PBA, sodium phenylbutyrate; HR, homologous recombination; RPA, replication protein A; HAT, histone acetyltransferase; YPD, yeast extract-peptone-dextrose; SC, synthetic complete; TSA, tr

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Schizosaccharomyces pombe Mms1 channels repair of perturbed replication into Rhp51 independent homologous recombination

Keywords: CPT، camptothecin; BER, base excision repair; ChIP, chromatin immunoprecipitation; CPT, camptothecin; D loop, displacement loop; DSB, double strand break; FPC, fork protection complex; HR, homologous recombination; HU, hydroxyurea; IR, ionizing radiation; MMS, methyl methan

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2011 سفارش ترجمه

COX-2 inhibitors block chemotherapeutic agent-induced apoptosis prior to commitment in hematopoietic cancer cells

Keywords: CPT، camptothecin; Bak, Bcl-2 homologous antagonist killer; Bax, Bcl-2-associated X protein; Bcl-2, B-cell lymphoma 2; Bcl-Xl, B-cell lymphoma-extra large; CPT, camptothecin; CISP, cisplatin; COX-2, cyclooxygenase-2; CTR-1, copper transporter 1; CYT, cytarabine; DMC, 2,5-di

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2011 سفارش ترجمه

Combination of arsenic trioxide and BCNU synergistically triggers redox-mediated autophagic cell death in human solid tumors

Keywords: CPT، camptothecin; APL, acute promyelocytic leukemia; AVO, acidic vesicular organelles; BCNU, N,N′-bis(2-chloroethyl)-N-nitrosourea; BSO, l-buthionine sulfoximine; CPT, camptothecin; DHA, docosahexaenoic acid; 5-FU, 5-fluorouracil; GR, glutathione reductase; GSH, reduced gl

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2011 سفارش ترجمه

Prodrug-based intracellular delivery of anticancer agents

Keywords: CPT، camptothecin; 5-FdU, 5-fluoro-2′-deoxyuridine; Ag, Antigen; ApoE, Apolipolipoprotein E; AraC, 1-β-d-Arabinofuranosylcytosine (cytarabine); BE, Benzyl elimination; CALI, NAc-gamma calicheamycin; CPP, Cell-penetrating peptide; CPT, Camptothecin; DAUN, Daunorubicin; dFdC,

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2011 سفارش ترجمه

Squalene protects against oxidative DNA damage in MCF10A human mammary epithelial cells but not in MCF7 and MDA-MB-231 human breast cancer cells

Keywords: CPT، camptothecin; AAPH, 2,2′-azobis (2-methylpropionamidine) dihydrochloride; ABTS, 2,2′-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid); CPT, camptothecin; DCFH-DA, 2′,7′-dichlorofluorescein diacetate; DMSO, dimethyl sulfoxide; DPPH, 2,2-diphenyl-1-picrylhydrazyl; EDTA,

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

An unusual DNA binding compound, S23906, induces mitotic catastrophe in cultured human cells

Keywords: CPT، camptothecin; CPT, camptothecin; CDDP, cisplatin; Cdk1, cyclin-dependent kinase 1; Chk1, checkpoint kinase 1Cytotoxic drug; Cyclin-dependent kinases; Cdk1; DNA damage response; Checkpoint kinase 1; Histone γ-H2AX; Checkpoint adaptation

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Divergent cellular phenotypes of human and mouse cells lacking the Werner syndrome RecQ helicase

Keywords: CPT، camptothecin; CFE, colony-forming efficiency; cis-Pt, cis-diammineplatinum(II)dichloride; CPT, camptothecin; WS, Werner syndrome; MearF, mouse ear fibroblastsWerner syndrome; RecQ helicase; Mouse model; Progeroid syndrome; Genetic instability

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2010 سفارش ترجمه

Down-regulation of adenine nucleotide translocase 3 and its role in camptothecin-induced apoptosis in human hepatoma QGY7703 cells

Keywords: CPT، camptothecin; ANT, adenine nucleotide translocase; CPT, camptothecin; MPTP, mitochondrial permeability transition pore; ΔΨm, mitochondrial membrane potentialCamptothecin; Adenine nucleotide translocase 3; Apoptosis; Hepatoma QGY7703 cell; Mitochondrial permeability tra

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Cytotoxicity and TOP1-targeting activity of 8- and 9-amino derivatives of 5-butyl- and 5-(2-N,N-dimethylamino)ethyl-5H-dibenzo[c,h][1,6]naphthyridin-6-ones

Keywords: CPT، camptothecin; Topoisomerase I-targeting agents; 5H-Dibenzo[c,h][1,6]naphthyridin-6-ones; Cytotoxicity; Multidrug resistanceTOP1, topoisomerase I; CPT, camptothecin

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

De novo ceramide synthesis is responsible for the anti-tumor properties of camptothecin and doxorubicin in follicular thyroid carcinoma

Keywords: CPT، camptothecin; CPT, camptothecin; DOX, doxorubicin; FB1, fumonisin B1; FTC, follicular thyroid carcinoma; GCS, glucosylceramide synthase; LASS, longevity assurance homolog; PDMP, phenyl-2-decanoylamino-3-morpholino-1-propanol; SMase, sphingomyelinase; TSP-1, thrombospon

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Nanoparticle-based targeted drug delivery

Keywords: CPT، camptothecin; BBB, blood–brain barrier; CPT, camptothecin; DT-A, diphtheria toxin suicide gene; DOX, doxorubicin; EPR, enhanced permeability and retention; PEO-PPO, ethylene oxide–propylene oxide block copolymer; C60, fullerenes; GBM, glioblastoma multiforme; GCS, gluc

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Dual inhibition of topoisomerase I and tubulin polymerization by BPR0Y007, a novel cytotoxic agent

Keywords: CPT، camptothecin; Top I, topoisomerase I; CPT, camptothecin; PLDBs, protein-linked DNA breaksTopoisomerase I; Tubulin; Dual inhibitor

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Frequent Inactivation of Axon Guidance Molecule RGMA in Human Colon Cancer Through Genetic and Epigenetic Mechanisms

Keywords: CPT، camptothecin; 5aza-dC, 5-aza-2′-deoxycytidine; BMP, bone morphogenetic protein; bp, base pair; CPT, camptothecin; CRC, colorectal cancer; DAPI, 4′,6-diamidino-2-phenylindole; DCC, deleted-in-colorectal cancer; LOH, loss of heterozygosity; MSP, methylation-specific poly

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2009 سفارش ترجمه

Delocalization of nucleolar poly(ADP-ribose) polymerase-1 to the nucleoplasm and its novel link to cellular sensitivity to DNA damage

Keywords: CPT، camptothecin; PARP-1, poly(ADP-ribose) polymerase-1; AIF, apoptosis induction factor; MNNG, N-methyl-N′-nitro-N-nitrosoguanidin; CPT, camptothecin; Topo I, topoisomerase I; PI, propidium iodidePARP-1; DNA damage; The nucleolus

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2009 سفارش ترجمه

Modulation of nucleobindin-1 and nucleobindin-2 by caspases

Keywords: CPT، camptothecin; CPT, camptothecin; NUCB1, nucleobindin-1; NUCB2, nucleobindin-2; TNT, coupled in vitro transcription and translationCaspase substrates; Nucleobindin-1 (NUCB1); Nucleobindin-2 (NUCB2); EF-hand motif; Ca2+-binding proteins; Cleavage of functional domain

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Development and validation of a reverse-phase HPLC with fluorescence detector method for simultaneous determination of CZ48 and its active metabolite camptothecin in mouse plasma

Keywords: CPT، camptothecin; CPT, camptothecin; CZ48, C20-propionate ester of camptothecin; Cmax, maximum plasma drug concentration following a single dose; Tmax, time to Cmax; Ke, the elimination rate constants; AUC0–t, area under the plasma drug concentration–time curve from time z

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

From bench to drug: Human seizure modeling using Drosophila

Keywords: CPT، camptothecin; AED, antiepileptic drug; BS, bang-sensitive Drosophila mutant; CNS, central nervous system; CPT, camptothecin; DLM, dorsal longitudinal muscle; ECS, electroconvulsive shock; ECT, electroconvulsive shock treatment; HF, high-frequency; PSI, peripherally syn

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Hyperphosphorylation of RNA Polymerase II in Response to Topoisomerase I Cleavage Complexes and Its Association with Transcription- and BRCA1-dependent Degradation of Topoisomerase I

Keywords: CPT، camptothecin; APD, aphidicolin; Cdk, cyclin-dependent kinase; CPT, camptothecin; CSK, cytoskeleton; CTD, carboxy-terminal domain; DRB, 5,6-dichlorobenzimidazole 1-β-d-ribofuranoside; FLV, flavopiridol; Pol II, RNA polymerase II; Pol IIa, hypophosphorylated Pol II; Pol

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Bloom's syndrome workshop focuses on the functional specificities of RecQ helicases

Keywords: CPT، camptothecin; ALT, alternative lengthening of telomeres; BS, Bloom's syndrome; CPT, camptothecin; dsDNA, double-stranded DNA; DSB, double-strand break; ES cells, embryonic stem cells; G4, G quartet; G4P, G4 DNA-forming potential; HR, homologous recombination; HU, hydro

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Gene tagging and gene replacement using recombinase-mediated cassette exchange in Schizosaccharomyces pombe

Keywords: CPT، camptothecin; 5-FOA, 5-fluoroorotic Acid; MCS, multiple cloning site; CPT, Camptothecin; YE, yeast extract; EMM, Edinburgh minimal media; PCR, polymerase chain reaction; kb, kilobase(s) or 1000 bp; S., Schizosaccharomyces.Cre recombination; Intron; RMCE; Epitope tag; C

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

γ-Secretase Inhibitors Enhance Taxane-Induced Mitotic Arrest and Apoptosis in Colon Cancer Cells

Keywords: CPT، camptothecin; APC, adenomatous polyposis coli; cdk, cyclin-dependent kinase; CPT, camptothecin; DAPT, N-[N-(3,5-difluorophenacetyl-l-alanyl)-S-phenylglycine]-t-butyl ester; FBS, fetal bovine serum; 5-FU, 5-fluorouracil; NICD, Notch intracellular domain; RT-PCR, reverse

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2008 سفارش ترجمه

Signal transduction events in aluminum-induced cell death in tomato suspension cells

Keywords: CPT، camptothecin; Aluminum; Antioxidants; Ethylene; Phospholipid signalling; Programmed cell death; TomatoAA, ascorbic acid; ACC, 1-aminocyclopropane-1-carboxylic acid; Al, aluminum; AVG, aminoethoxy vinylglycine; CPT, camptothecin; DAG, diacylglycerol; FDA, fluorescein di

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Vasoactive intestinal peptide–camptothecin conjugates inhibit the proliferation of breast cancer cells

Keywords: CPT، camptothecin; VIP, vasoactive intestinal peptide; CPT, camptothecin; PACAP, pituitary adenylate cyclase activating polypeptide; (A-NL-K)VIP, (Ala2,8.9.19.24.25.27, Nle17, Lys28) VIP; Ki, inhibitory constant; L2, N-(N-methyl-amino-ethyl)-glycine carbamate; IP, inositol

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Mutation of a Conserved Active Site Residue Converts Tyrosyl-DNA Phosphodiesterase I into a DNA Topoisomerase I-dependent Poison

Keywords: CPT، camptothecin; Tdp1, tyrosyl-DNA phosphodiesterase; Top1, topoisomerase I; CPT, camptothecin; 3′PG, 3′phosphoglycolate; SCAN1, spinocerebellar ataxia with axonal neuropathy; MAD, multiple anomalous dispersion; ssDNA, single-strand DNAcamptothecin; DNA topoisomerase I; e

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2007 سفارش ترجمه

Circadian regulation of mouse topoisomerase I gene expression by glucocorticoid hormones

Keywords: CPT، camptothecin; Topo I, topoisomerase I; CPT, camptothecin; CORT, corticosterone; CPT-11, 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin; ICR, Institute of Cancer Research; RU486, 11β-(4-dimethyl-amino)phenyl-17β-hydroxy-17-(1-propynyl)estra-4,9-dien-3

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Involvement of ethylene and lipid signalling in cadmium-induced programmed cell death in tomato suspension cells

Keywords: CPT، camptothecin; Antioxidants; Cadmium; Calcium; Ethylene; Lycopersicon esculentum Mill.; Phospholipids; Programmed cell death; Tomato cell cultureAA, ascorbic acid; AVG, aminoethoxy vinylglycine; CPT, camptothecin; DEVD-CMK, Asp-Glu-Val-Asp-chloromethylketone; DPI, diphe

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Chemotherapy induces an increase in coenzyme Q10 levels in cancer cell lines

Keywords: CPT، camptothecin; 4AB, 4-aminobenzoate; BHA, butylated hydroxianisole; CPT, camptothecin; CoQ, coenzyme Q10; COX, cytochrome c oxidase; H2DCF-DA, carboxy-2′,7′-dichlorodihydrofluorescein diacetate; ETOP, etoposide; DOXO, doxorubicin; IOD, integrated optical density; LOV, l

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه