Keywords: ACTB; actin-β; ACTG1; actin-γ1; ADA; American Diabetes Association; Ascl1; achaete-scute homolog 1; BMPR2; bone morphogenetic protein receptor type 2; CCNG2; cyclin G2; CNS; central nervous system; CRKL; CRK-like proto-oncogene adaptor protein; CSNK2A2;
مقالات ISI (ترجمه نشده)
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Keywords: AKT1/AKT; AKT serine/threonine kinase 1; AXL; AXL receptor tyrosine kinase; Bmi1; BMI1 proto-oncogene, polycomb ring finger; CAF; cancer-associated fibroblast; CDH/CAD; cadherin; CRKL; CRK Like Proto-Oncogene; CSC; cancer stem cell; CSF-1; colony-stimulat
Keywords: ADCC; antibody-dependent cell-mediated cytotoxicity; AP3; adaptor protein 3; CHS; Chediak-Higashi syndrome; CMV; cytomegalovirus; CNKD; classical natural killer cell deficiency; CrkL; chicken tumor virus number 10 regulator of kinase-like; CTL; cytotoxi
Manganese exposure: Linking down-regulation of miRNA-7 and miRNA-433 with α-synuclein overexpression and risk of idiopathic Parkinson's disease
Keywords: BCL2; B-cell CLL/lymphoma 2; CCND1; cyclin D1; CCNE1; cyclin E1; CRKL; V-Crk avian sarcoma virus CT10 oncogene homolog-like; FGF20; fibroblast growth factor 20; FGF7; fibroblast growth factor 7; FOXO1; forkhead box protein O1A; GRB2; growth factor recepto
TCR crosslinking promotes Crk adaptor protein binding to tyrosine-phosphorylated CD3ζ chain
Keywords: T cell activation; TCR/CD3 crosslinking; CD3ζ chain; Crk adaptor proteins; Tyrosine phosphorylation; Signal transduction; C3G; Crk SH3 domain-binding guanine nucleotide-releasing factor; Crk; CT10 (chicken tumor virus number 10) regulator of kinase; CrkL
Crk adaptor proteins regulate CD3ζ chain phosphorylation and TCR/CD3 down-modulation in activated T cells
Keywords: Abl; Abelson tyrosine kinase; C3G; Crk SH3 domain-binding guanine nucleotide-releasing factor; Cbl; Casitas B-lineage lymphoma; CD3ζY1-6F; CD3ζ mutant in which all 6 tyrosines were replaced by phenylalanine; Crk; CT10 (chicken tumor virus number 10) reg
The effects of Micro-429 on inhibition of cervical cancer cells through targeting ZEB1 and CRKL
Keywords: miR-429; ZEB1; CRKL; Invasion; Cervical cancer
Reduction of CRKL expression in patients with partial DiGeorge syndrome is associated with impairment of T-cell functions
Keywords: CRKL; DiGeorge syndrome; c-Fos; proliferation; T-cell receptor activation; IL-2; signal transducer and activator of transcription 5; AP-1; Activator protein 1; APC; Allophycocyanin; CFSE; Carboxyfluorescein succinimidyl ester; CRKL; Crk-like; del22q11; De
CRKL overexpression suppresses in vitro proliferation, invasion and migration of murine hepatocarcinoma Hca-P cells
Keywords: CRKL; Hepatocarcinoma; Proliferation; Invasion; Migration
Reorganization of the host cell Crk(L)-PI3 kinase signaling complex by the influenza A virus NS1 protein
Keywords: Influenza NS1 protein; SH3 domain; Crk; CrkL; PI3K; Signal transduction;
CrkL meditates CCL20/CCR6-induced EMT in gastric cancer
Keywords: CrkL; CCL20/CCR6; Erk1/2; EMT; Gastric cancerCCL20, chemokine (C–C motif) ligand 20; CCR6, CC chemokine receptor; CrkL, Crk-like adapter protein; EMT, epithelial-to-mesenchymal transition; Erk1/2, the extracellular signal-regulated kinase 1 and 2; FBS, fe
CRKL knockdown promotes in vitro proliferation, migration and invasion, in vivo tumor malignancy and lymph node metastasis of murine hepatocarcinoma Hca-P cells
Keywords: CRKL; Hepatocarcinoma; Proliferation; Migration; Invasion; Metastasis
Quantitative comparison of CrkL-SH3 binding proteins from embryonic murine brain and liver: Implications for developmental signaling and the quantification of protein species variants in bottom-up proteomics
Keywords: Quantitative proteomics; CrkL; Crk; SH3; C3G; Splice variants; Protein species variants
MAPK-induced Gab1 translocation to the plasma membrane depends on a regulated intramolecular switch
Keywords: Crk; CT10 regulator of kinase; CRKL; Crk-like protein; ERK; extracellular signal regulated kinase; FCS; foetal calf serum; Gab1; Grb2-associated binder 1; Grb2; growth factor receptor bound protein 2; IL-6; interleukin-6; JAK; Janus kinase; HEK; human emb
Tyrosine phosphorylation of the orphan receptor ESDN/DCBLD2 serves as a scaffold for the signaling adaptor CrkL
Keywords: ESDN; endothelial and smooth muscle cell-derived neuropilin-like protein; DCBLD2; discoidin CUB and LCCL domain containing 2; CUB; complement C1r/C1s Uegf Bmp1; CrkL; CrkCT10 regulator of kinase Crk-Like; SFK; Src family tyrosine kinase; Cas; Crk-associat
Crystal structure of Src-like adaptor protein 2 reveals close association of SH3 and SH2 domains through β-sheet formation
Keywords: βME; β-mercaptoethanol; CrkL; Crk-like; DTT; dithiothreitol; Itk; interleukin-2 tyrosine kinase; SLAP; Src-like adaptor protein; SFK; Src family kinase; SH; Src-homology; SDS-PAGE; sodium dodecyl sulfate polyacrylamide gel electrophoresis; TCR; T cell r
Association study between genes in Reelin signaling pathway and autism identifies DAB1 as a susceptibility gene in a Chinese Han population
Keywords: DAB1; Dab, reelin signal transducer, homolog 1 (Drosophila); FYN; FYN oncogene related to SRC, FGR, YES; SRC; v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian); CRK; v-crk sarcoma virus CT10 oncogene homolog (avian); CRKL; v-crk sarcoma vi
CRKL promotes cell proliferation in gastric cancer and is negatively regulated by miR-126
Keywords: CRKL; miR-126; Gastric cancer; Cell proliferation;
Dab1 stabilizes its interaction with Cin85 by suppressing Cin85 phosphorylation at serine 587
Keywords: Dab1; Cin85; Reelin; Phosphorylation; CrkL; KinaseDab1, disabled-1; CIN85, Cbl-interacting protein of 85 kDa; ApoER2, apolipoprotein E receptor 2; Crk, CT10-regulator of kinase; CrkL, Crk-like; SFK, Src family kinase; SH3, Src homology-3 domain; SH2, Src
A perspective on non-catalytic Src homology (SH) adaptor signalling proteins
Keywords: Src Homology domain; Adaptor protein; Signal transduction; CrkL; Grb2; Nck
Beyond 'furballs' and 'dumpling soups' - towards a molecular architecture of signaling complexes and networks
Keywords: Abl; Abelson tyrosine-protein kinase 1; ADAP1; arf-GAP with dual PH domain-containing protein 1; AFM; atomic force microscopy; cAMP; cyclic adenosine monophosphate; ApoER2; apolipoprotein E receptor 2; BCAR1; breast cancer anti-estrogen resistance 1; p130
Intracellular adaptor molecules and AR signalling in the tumour microenvironment
Keywords: Androgen receptor; CRKL; Casodex; Intracellular adaptor molecules
Predictability of the response to tyrosine kinase inhibitors via in vitro analysis of Bcr-Abl phosphorylation
Keywords: CML; Tyrosine kinase inhibitor; Bcr-Abl; Crkl; Phosphorylation; Immunoblot;
Interaction between AR signalling and CRKL bypasses casodex inhibition in prostate cancer
Keywords: Androgen receptor; CRKL; Prostate cancer; Signal transduction
Phosphorylation levels of BCR-ABL, CrkL, AKT and STAT5 in imatinib-resistant chronic myeloid leukemia cells implicate alternative pathway usage as a survival strategy
Keywords: Chronic myeloid leukemia; BCR-ABL; CrkL; AKT; STAT5; Imatinib; Resistance; Survival pathways; Tyrosine kinase
CrkL plays a role in SDF-1-induced activation of the Raf-1/MEK/Erk pathway through Ras and Rac to mediate chemotactic signaling in hematopoietic cells
Keywords: CrkL; SDF-1; Lyn; Chemotaxis; Rac; Ras; Rap1; Erk
Interaction of Bcr/Abl with C3G, an exchange factor for the small GTPase Rap1, through the adapter protein Crkl
Keywords: Ph-positive leukemia; P190; P210; Crkl; Activation of guanine nucleotide exchange activity;
Hepatocyte growth factor, its receptor, and their potential value in cancer therapies
Keywords: Abl; Abelson murine leukemia viral oncogene; AGTR; angiotensin II receptor; Arf; Archaeal Rieske-type ferredoxin; Arp; actin-related protein; BCL2; B-cell CLL/lymphoma 2; BID; BH3 interacting domain death agonist; cMET; receptor for hepatocyte growth fact