Keywords: Cx، connexin; 4-PB, 4-phenylbutyrate; AZA, 5-azacytidine; Cx, connexin; DAC, decitabine; DNMT(i), DNA methyltransferase (inhibitor); EG, epigallocatechin-3-gallate; HDAC(i), histone deacetylase (inhibitor); HMBA, hexamethylene bisacetamide; J-1, 5-(4-dimethylaminobenzo
مقالات ISI Cx، connexin (ترجمه نشده)
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Keywords: Cx، connexin; 4AP, 4-aminopyridine; ACSF, artificial cerebrospinal fluid; CBX, carbenoxolone; Cx, connexin; CNQX, 6-cyano-7-nitro-quinoxaline-2,3-dione disodium salt; CPP, 3,3-(2-carboxypiperazine-4-yl)-propylphosphonate; GABA, γ-amino-butyric acid; GJ, Gap Junction; P
Keywords: Cx، connexin; GJ, gap junction; Cx, connexin; PKC, proteine kinase C; PKCps, phosphorylated PKC substrate; A, adenosine; ARs, adenosine receptor subtypes; LVD, left ventricular dysfunction; RV, right ventricle; LV, left ventricle; LVEDD, left ventricle end diastolic di
Keywords: Cx، connexin; ATP, adenosine triphosphate; CagA, cytotoxin-associated gene A; Cx, connexin; GJIC, gap junctional intercellular communication; HCC, hepatocellular carcinoma; mRNA, messenger RNA; Panx, pannexin; VacA, vacuolating toxin A
Keywords: Cx، connexin; AM, acetoxymethyl ester; CBX, carbenoxolone; Cx, connexin; EGCG, epigallocatechin gallate; FRAP, fluorescence recovery after photobleaching; GJ, gap junction; GJIC, gap junctional intercellular communication; YFP, yellow fluorescent proteinTerbinafine; Na
Data of the molecular dynamics simulations of mutations in the human connexin46 docking interface
Keywords: Cx، connexin; CL, cytoplasmic loop; Cx, connexin; DOPE, discrete optimized protein energy; E2, second extracellular loop; HB, hydrogen bond; hCx, human connexin; MD, molecular dynamics; SCAM, substituted cysteine accessibility method; wt, wild type
Connexin 43, breast cancer tumor suppressor: Missed connections?
Keywords: Cx، connexin; Breast cancer; Connexin 43; Gap junctions; MetastasisCx43, connexin 43; Cx, connexin; GJIC, gap junction intercellular communication; WT, wildtype; ErbB2, epidermal growth factor receptor 2; ZO-1, zona occludens-1; ZO-2, zona occludens-2; TCDD, 2,3,7,8-te
Connexin43 hemichannels contributes to the disassembly of cell junctions through modulation of intracellular oxidative status
Keywords: Cx، connexin; Cx, connexin; Cx43, connexin43; TJs, tight junctions; AJs, adherens junctions; GJs, gap junctions; siRNA, small interfering RNA; Cx43+/+, Cx43 wide-type mouse; Cx43+/-, Cx43 heterozygous mouse; Cx43-/-, Cx43 knockout mouse; JNK, c-Jun N-terminal kinase; G
Connexin45 contributes to global cardiovascular development by establishing myocardial impulse propagation
Keywords: Cx، connexin; AV, atrioventricular; CA, cardiac α-actin; CM, cardiac myocyte; cTnT, cardiac troponin T; Cx, connexin; E, embryonic day; EMT, epithelial–mesenchymal transformation; NFATc, nuclear factor of activated T-cells cytoplasmic; TRP, transient receptor potential
Models and methods for in vitro testing of hepatic gap junctional communication
Keywords: Cx، connexin; cAMP, cyclic adenosine monophosphate; Cx, connexin; DMSO, dimethyl sulfoxide; ECM, extracellular matrix; FRAP, fluorescence recovery after photobleaching; GJIC, gap junctional intercellular communication; HDAC(s), histone deacetylase(s); LAMP, local activ
Cx43 increases serum induced filopodia formation via activation of p21-activated protein kinase 1
Keywords: Cx، connexin; Aa, amino acids; Cx, connexin; CT, C-terminal part; Hsp27, heat shock protein 27; NT, N-terminal part; PAK1, p21-activated protein kinase 1Connexin; Gap junction independent; Actin cytoskeleton; Migration; p38
Astrocyte physiopathology: At the crossroads of intercellular networking, inflammation and cell death
Keywords: Cx، connexin; Ca2+, calcium; [Ca2+]i, intracellular concentration of calcium ions; BBB, blood–brain barrier; GFAP, glial fibrillary acidic protein; GS, glutamine synthetase; Cx, connexin; K+, potassium; Kir, inward rectifying potassium channel; NMDA, N-methyl-d-asparta
Glioma-associated microglia and macrophages/monocytes display distinct electrophysiological properties and do not communicate via gap junctions
Keywords: Cx، connexin; GAM, glioma-associated microglia; GAMP, glioma-associated macrophage; GJ, gap junction; GJC, gap junctional coupling; Cx, connexin; FACS, fluorescence-activated cell sortingGlioma-associated microglia; Glioma-associated macrophages/monocytes; Glioma; Gap
Endothelial connexin32 enhances angiogenesis by positively regulating tube formation and cell migration
Keywords: Cx، connexin; GJs, gap junctions; GJIC, gap junction intercellular communication; Cx, connexin; HUVECs, human umbilical vein endothelial cells; mAb, monoclonal antibody; pAb, polyclonal antibody; PCR, polymerase chain reaction; DAPI, 4',6-diamidino-2-phenylindole; PBS,
Coxsackie and Adenovirus Receptor Is a Modifier of Cardiac Conduction and Arrhythmia Vulnerability in the Setting of Myocardial Ischemia
Keywords: Cx، connexin; arrhythmia; ion channels; ischemia; single nucleotide polymorphism genetics; ventricular fibrillationAP, action potential; CAR, coxsackie and adenovirus receptor; CVL, longitudinal conduction velocity; CVT, transversal conduction velocity; Cx, connexin; G
Physiological bases of the K+ and the glutamate/GABA hypotheses of epilepsy
Keywords: Cx، connexin; AIS, axon initial segment; AMPA, alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; AQP4, aquaporin-4; Best1, bestrophin 1 channel; Cav, voltage-gated Ca2+ channel; Cx, connexin; EAAT, excitatory amino acid transporter; FBPase, fructose-1,6-bisphos
Digenic inheritance in autosomal recessive non-syndromic hearing loss cases carrying GJB2 heterozygote mutations: Assessment of GJB4, GJA1, and GJC3
Keywords: Cx، connexin; Cx, connexin; GJ, gap junction; HL, hearing loss; ARNSHL, autosomal recessive non-syndromic hearing lossDigenic inheritance; Hearing loss; Connexin; GJB2; GJB4; GJA1
Simvastatin attenuates the additive effects of TNF-α and IL-18 on the connexin 43 up-regulation and over-proliferation of cultured aortic smooth muscle cells
Keywords: Cx، connexin; Cx, connexin; DAB, 3,3′-diaminobenzidine; ERK, extracellular signal-regulated kinase; HCD, high-cholesterol diet; HDL-C, high density lipoprotein cholesterol; H&E, hematoxylin–eosin; IL-18, interleukin-18; IFN-γ, interferon-γ; IHC, immunohistochemistry; J
Gingko biloba extracts protect auditory hair cells from cisplatin-induced ototoxicity by inhibiting perturbation of gap junctional intercellular communication
Keywords: Cx، connexin; ABR, auditory brainstem response; ANOVA, analysis of variance; CDDP, cis-diamine-dichloroplatinum II; Cx, connexin; DAPI, 4′,6-diamidino-2-phenylindole; DMEM, Dulbecco’s modified Eagle medium; EDTA, ethylenediaminetetraacetic acid; EGb, extract of Gingko
Flufenamic acid as an ion channel modulator
Keywords: Cx، connexin; BKCa, big K+ channel; BLINaC, brain liver intestine Na+ channel; CaCC, Ca2+-activated chloride current; CFTR, cystic fibrosis transmembrane conductance regulator; ClC, chloride channel; ClC-K, chloride channel kidney; Cx, connexin; EC50, concentration for
Variety of horizontal cell gap junctions in the rabbit retina
Keywords: Cx، connexin; CX, connexin; GCL, ganglion cell layer; HC, horizontal cell; INL, inner nuclear layer; IPL, inner plexiform layer; ONL, outer nuclear layer; OPL, outer plexiform layerGap junction; Cx50; Cx57; Electron microscopy; Horizontal cells; Rabbit retina
Gap26, a connexin mimetic peptide, inhibits currents carried by connexin43 hemichannels and gap junction channels
Keywords: Cx، connexin; Cx, connexin; GJC, gap junction channels; GJ, gap junction; HC, hemichannels; EL1, extracellular loopGap26; Connexin43; Hemichannel; Gap junction channel; Electrophysiology
Re-establishment of gap junctional intercellular communication (GJIC) between human endometrial carcinomas by prostaglandin E2
Keywords: Cx، connexin; Cx, connexin; DIC, differential interference contrast; ELISA, enzyme linked immunosorbent assay; GJIC, gap junctional intercellular communication; IL-1, interleukin 1; KDa, kilodalton; LiCl, lithium chloride; Min, multiple intestinal neoplasia; PGE1, pros
Low extracellular Ca2+ conditions induce an increase in brain endothelial permeability that involves intercellular Ca2+ waves
Keywords: Cx، connexin; BCEC, bovine brain capillary endothelial cells; BK, bradykinin; Cx, connexin; CaMKII, Ca2+/calmodulin-dependent kinase II; DF, dextran fluorescein; ICW, intercellular Ca2+ wave; IP3, inositol-trisphosphate; LY, lucifer yellow; MLC, myosin light chain; PKC
NADPH oxidase-mediated upregulation of connexin43 contributes to podocyte injury
Keywords: Cx، connexin; DMNQ, 2,3-dimethoxy-1,4-naphthoquinone; SIN-1, 3-morpholinosydnonimine; α–GA, α-glycyrrhetinic acid; Cx, connexin; Cx43, connexin43; DPI, diphenyleneiodonium chloride; FFA, flufenamic acid; GJIC, gap-junctional intercellular communication; LY, lucifer yel
Two-Dimensional Kinetics of Inter-Connexin Interactions from Single-Molecule Force Spectroscopy
Keywords: Cx، connexin; Cx, connexin; 2D, two-dimensional; AFM, atomic force microscopy; DFS, dynamic force spectroscopy; PEG, polyethylene glycolgap junctions; connexins; adhesion; 2D kinetics; atomic force microscopy
Treatment with connexin 46 siRNA suppresses the growth of human Y79 retinoblastoma cell xenografts in vivo
Keywords: Cx، connexin; gap junction; GJA3; connexin 46; retinoblastoma; hypoxia; Y79 retinoblastoma cells; xenograftHIF, hypoxia-inducible factor; Cx, connexin; N2A, neuronal2A cells; siRNA, short interfering RNA; GJIC, gap junction intercellular communication; HLEC, human lens
Evaluation of the multipotent character of human foreskin-derived precursor cells
Keywords: Cx، connexin; ADM, adipocyte differentiation medium; ALB, albumin; AFP, alpha-foetoprotein; BDNF, brain-derived neurotrophic factor; BPE, bovine pituitary extract; C/EBP, CCAAT-enhancer bindings protein; CK, cytokeratin; Cx, connexin; FGF, fibroblast growth factor; dex
Altered differentiation and clustering of Sertoli cells in transgenic mice showing a Sertoli cell specific knockout of the connexin 43 gene
Keywords: Cx، connexin; Sertoli; Connexin 43; Knockout; Mouse; Differentiation; Cell clusterAMH, anti-Muellerian hormone; AR, androgen receptor; β-Gal, beta-galactosidase; 3β-HSD, 3-beta-hydroxysteroid dehydrogenase; BSA, bovine serum albumin; Cx, connexin; BTB, blood–testis-bar
Changes in hippocampal connexin 36 mRNA and protein levels during epileptogenesis in the kindling model of epilepsy
Keywords: Cx، connexin; ACSF, Artificial Cerebrospinal Fluid; AD, After-discharge; AMV, Avian Myeloblastoma Virus; bp, base pair; cDNA, Complementary Deoxyribonucleic acid; CNS, Central Nervous System; Cx, Connexin; ECL, Enhanced Chemiluminescence; i.c.v, intracerebroventricular
Connexin 26 (GJB2) mutations as a cause of the KID syndrome with hearing loss
Keywords: Cx، connexin; Cx, connexin; EP, endocochlear potential; ABR, auditory brainstem responses; GFP, green fluorescent proteinConnexin; Gap junctions; Mutations; KID syndrome; Deafness; Cell death
Expression of connexin57 in mouse development and in harmaline-tremor model
Keywords: Cx، connexin; gap junction; rodent; brain; neuronsBSA, bovine serum albumin; Cx, connexin; Cx57, connexin57; DEPC, diethyl pyrocarbonate; FITC, fluorescein isothiocyanate; GFAP, glial fibrillary acidic protein; GJ, gap junction; GJIC, gap junctional intercellular commu
Rac1-Induced Connective Tissue Growth Factor Regulates Connexin 43 and N-Cadherin Expression in Atrial Fibrillation
Keywords: Cx، connexin; atrial fibrillation; Rac1; CTGF; oxidative stress; connexin 43AF, atrial fibrillation; CTGF, connective tissue growth factor; Cx, connexin; ECG, electrocardiography; GTPase, guanosine triphosphatase; HMG-CoA, 3-hydroxy-3-methylglutaryl-coenzyme A; LA, lef
Connexin-mediated communication controls cell proliferation and is essential in retinal histogenesis
Keywords: Cx، connexin; BSA, bovine serum albumin; CB, calbindin-D; CBX, carbenoxolone; Cx, connexin; GFAP, glial fibrillary acidic protein; GJ, gap junction; kDa, kilo Dalton; Ki67, antigen identified by monoclonal antibody Ki-67; PB, phosphate buffer; PCNA, proliferating cell
Pharmacological and genetic approaches to study connexin-mediated channels in glial cells of the central nervous system
Keywords: Cx، connexin; CNS, central nervous system; Cx, connexin; GJC, gap junction channel; HC, hemichannel; Panx, pannexin; PNS, peripheral nervous system; RG, radial glia; SGZ, subgranular zoneGap junction; Hemichannel; Astrocyte; Oligodendrocyte; Glial network
Bystander effect from cytosine deaminase and uracil phosphoribosyl transferase genes in vitro: A partial contribution of gap junctions
Keywords: Cx، connexin; CD, cytosine deaminase; CodA, cytosine deaminase gene; Cx, connexin; 5-FC, 5-fluorocytosine; 5-FU, 5-fluorouracil; GJIC, gap junctional intercellular communication; upp, uracil phosphoribosyl transferaseBystander effect; Gap junction; Cytosine deaminase;
Differential regulation of the hydrogen-peroxide-induced inhibition of gap-junction intercellular communication by resveratrol and butylated hydroxyanisole
Keywords: Cx، connexin; ABTS, 2,2′-azinobis(3-ethylbenzthiazoline-6-sulfonic acid) diammonium salt; DPPH, 1,1-diphenyl-2-picrylhydrazyl; BHA, butylated hydroxyanisole; Cx, connexin; ERK 1/2, extracellular-signal-regulated protein kinase 1/2; GJIC, gap-junction intercellular comm
Characterization and hepatic differentiation of skin-derived precursors from adult foreskin by sequential exposure to hepatogenic cytokines and growth factors reflecting liver development
Keywords: Cx، connexin; ALB, albumin; AFP, alpha-foetoprotein; CK, cytokeratin; Cx, connexin; D, differentiation day; FGF, fibroblast growth factor; HGF, hepatocyte growth factor; HNF, hepatocyte nuclear factor; hSKP, human skin-derived precursors; ITS, insulin–transferrin–selen
Changes in microRNA-1 expression and IK1 up-regulation in human atrial fibrillation
Keywords: Cx، connexin; Inward rectifier potassium currents; IKACh; IK1; connexin; atrial fibrillation; microRNAAF, atrial fibrillation; BSA, bovine serum albumin; CAD, coronary artery disease; Cx, connexin; DTT, dithiothreitol; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; L
Upregulation and maintenance of gap junctional communication in lens cells
Keywords: Cx، connexin; lens; gap junctions; connexin; proteasome; ERKATO, arsenic trioxide; BFA, brefeldin A; Cx, connexin; DCDMLs, dissociated cell-derived monolayers; ERK, extracellular signal-regulated kinase; FGF, fibroblast growth factor; GJIC, gap junction-mediated interc
Eps15 interacts with ubiquitinated Cx43 and mediates its internalization
Keywords: Cx، connexin; Cx, connexin; GJIC, gap junction intercellular communication; CME, Clathrin-mediated endocytosis; UIM, ubiquitin-interacting motifCx43; Eps15; Ubiquitin; Endocytosis; Nedd4
Perturbing plasma membrane hemichannels attenuates calcium signalling in cardiac cells and HeLa cells expressing connexins
Keywords: Cx، connexin; Connexin mimetic peptides; Gap 26; Gap 27; Intracellular calcium stores; Myocytes; HL-1 cells18-GA, 18alpha-glycyrrhetinic acid; Cx, connexin; CxHc, connexin hemichannels (connexons); IP3, inositol-tris-phosphate; RyR, ryanodine receptor
Diverse deafness mechanisms of connexin mutations revealed by studies using in vitro approaches and mouse models
Keywords: Cx، connexin; 2-NBDG, 2-[N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino]-2-deoxy-d-glucose; Cx, connexin; eGFP, enhanced green fluorescent protein; EP, endolymphatic potential; GJ, gap junction; IP3, inositol 1,4,5-trisphosphate; Panxs, pannexins; ROS, reactive oxygen spec
Atrial-Selective Approaches for the Treatment of Atrial Fibrillation
Keywords: Cx، connexin; AF, atrial fibrillation; AP, action potential; APD, action potential duration; Cx, connexin; DPO, diphenylphosphine oxide; ERP, effective refractory period; IKACh, acetylcholine-regulated potassium current; IKr, rapid delayed-rectifier potassium current;
Double-membrane gap junction internalization requires the clathrin-mediated endocytic machinery
Keywords: Cx، connexin; AGJ, annular gap junction; AP-2, adaptor protein complex 2; CHC, clathrin heavy chain; CME, clathrin-mediated endocytosis; Cx, connexin; Dab2, disabled 2; GJ, gap junction; KD, knockdown; PM, plasma membrane; RNAi, RNA interference; Trfn, transferrinAnnul
Gossypol repressed the gap junctional intercellular communication between Sertoli cells by decreasing the expression of Connexin43
Keywords: Cx، connexin; Cx, connexin; DMEM, Dulbecco modified eagle medium; DMSO, dimethyl sulphoxide; FCB, fetal calf serum; GJIC, gap junctional intercellular communication; SLDT, scrape loading and dye transferGossypol; Sertoli cells; Gap junctional intercellular communicatio
Connexin 43 contributes to differentiation of retinal pigment epithelial cells via cyclic AMP signaling
Keywords: Cx، connexin; RPE, retinal pigment epithelium; Cx, connexin; GJIC, gap-junctional intercellular communication; CNV, choroidal neovascularization; AMD, age-related macular degeneration; shRNA, short hairpin RNA; rCx43, rat connexin 43; bFGF, basic FGF; CRALBP, cellular
Differential effects of hydroxamate histone deacetylase inhibitors on cellular functionality and gap junctions in primary cultures of mitogen-stimulated hepatocytes
Keywords: Cx، connexin; 4-Me2N-BAVAH, 5-(4-dimethylaminobenzoyl)-aminovaleric acid hydroxamide; AhRR, aryl hydrocarbon receptor repressor; BSA, bovine serum albumin; Cx, connexin; CYP, cytochrome P450; DAPI, diamidinophenylindole; EGF, epidermal growth factor; EROD, 7-ethoxyreso
Connexin26 expression is associated with aggressive phenotype in human papillary and follicular thyroid cancers
Keywords: Cx، connexin; Cx, connexin; PTC, thyroid papillary carcinoma; FTC, thyroid follicular carcinoma; FTA, thyroid follicular adenoma; GJIC, gap junction intercellular communicationConnexin26; Thyroid cancer; D2-40; CD34
Lack of photoreceptor signaling alters the expression of specific synaptic proteins in the retina
Keywords: Cx، connexin; plasticity; synapse; connexin; synaptophysin; synapsin; retinaCT, cycle threshold; Cx, connexin; GJ, gap junction; PB, phosphate buffer; rd/rd, (retinal degeneration) mouse model; WT, wild-type