Keywords: 8-Hydroxy-efavirenz; CYP2B6; Time-dependent CYP450 induction; Thiolomic signature; S-thiolated proteins;
مقالات ISI (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: VPA; valproic acid; FABP2; fatty acid binding protein 2; UGT1A6; uridine diphosphate glucuronosyltransferase family 1 member A6; UGT2B7; uridine diphosphate glucuronosyltransferase family 2 member B7; CYP2C9; cytochrome P450 family 2 subfamily C member 9;
Keywords: anesthesia – genetics; pharmacogenetics; drug–drug interactions; drug–gene interactions; CYP2D6; CYP3A4; CYP2B6; opioid metabolism; OPRM1; OPRK1; UGT2B7; COMT; GABA; ABCB1; MC1R
Keywords: CAR; constitutive androstane receptor; CYP2B6; cytochrome P450 2B6; CYP3A4; cytochrome P450 3A4; DMSO; dimethyl sulfoxide; GR; glucocorticoid receptor; HBSS; Hanks' balanced salt solution; hCAR; human constitutive androstane receptor; hGR; human glucoco
Keywords: ATF-4; activating transcription factor-4; ARNT; aryl hydrocarbon receptor nuclear translocator; bHLH; basic helix-loop-helix; BBB; Basso, Beattie, and Bresnahan; cFLIP; cellular FLICE-inhibitory protein; cyt C; cytochrome C; Cygb; cytoglobin; CYP2B6; cyto
Keywords: Nicotine; Addiction; Adolescent; Smoking; Genetics; CYP2A6; CYP2B6
A CYP2B6-humanized mouse model and its potential applications
Keywords: CYP2B6; Liver; Drug metabolism; Xenobiotic toxicity; Knockout mice; Humanized mice; WT; wild-type; CYPs; cytochromes P450; CAR; constitutive androstane receptor; PXR; pregnane X receptor; GR; glucocorticoid receptor; PB; phenobarbital; and DEX; dexamethas
Investigation of miR-136-5p key target genes and pathways in lung squamous cell cancer based on TCGA database and bioinformatics analysis
Keywords: LUSC; lung squamous cell cancer; TCGA; the Cancer Genome Atlas; GTEx; genotype-tissue expression; UGT1A1; UDP glucuronosyltransferase family 1 member A1; UGT1A3; UDP glucuronosyltransferase family 1 member A3 UGT1A6 UDP glucuronosyltransferase family 1 me
Functional characterization of 40 CYP2B6 allelic variants by assessing efavirenz 8-hydroxylation
Keywords: Efavirenz (PubChem CID: 64139); 8-Hydroxyefavirenz (PubChem CID: 487643); 7-Ethoxy-4-trifluorometylcoumarin (PubChem CID: 24869840); 7-Hydroxy-4-trifluoromethylcoumarin (PubChem CID: 24862915); Dimanganese decacarbonyl (PubChem CID: 517769); Sodium hydros
Ketamine and ketamine metabolites as novel estrogen receptor ligands: Induction of cytochrome P450 and AMPA glutamate receptor gene expression
Keywords: Ketamine; Ketamine metabolites; Estrogens; CYP2A6; CYP2B6; AMPA receptors;
Full length articleGenetic and methylation variation in the CYP2B6 gene is related to circulating p,pâ²-dde levels in a population-based sample
Keywords: GWAS; CYP2B6; DDE; Metabolism; Methylation;
The CYP2B6 G516T polymorphism influences CD4+ T-cell counts in HIV-positive patients receiving antiretroviral therapy in an ethnically diverse region of the Amazon
Keywords: HIV-1; CYP2B6; Miscegenation; Antiretroviral drugs; Treatment response;
Pharmacogenetics of ecstasy: CYP1A2, CYP2C19, and CYP2B6 polymorphisms moderate pharmacokinetics of MDMA in healthy subjects
Keywords: 3,4-Methylenedioxymethamphetamine; 3,4-Methylenedioxyamphetamine; Pharmacokinetics; CYP1A2; CYP2C19; CYP2B6;
Association of CYP2B6 gene polymorphisms and anti-tuberculosis drug-induced hepatotoxicity in a Chinese population
Keywords: TB; tuberculosis; ADR; adverse drug reaction; ATDH; Anti-TB drug-induced hepatotoxicity; DDI; drug-drug interaction; HIV; human immunodeficiency virus; NAT2; N-acetyltransferase 2; CYP; cytochrome P450; GST; glutathione S-transferase; ALT; alanine aminotr
Nitric oxide-regulated proteolysis of human CYP2B6 via the ubiquitin-proteasome system
Keywords: AAF; L-alanyl-N-[(1S)â3-chloro-2-oxo-1-(phenylmethyl)propyl]-L-alaninamide, mono trifluoro-acetate; ALLN; N-acetyl-L-leucyl-N-[(1S)â1-formylpentyl]-L-leucinamide; Cal III; N-[(1S)â1-[[(1-formyl-2-phenylethyl)amino]carbonyl]â2-methylpropyl]-carbami
Regular ArticlePrecise prediction of activators for the human constitutive androstane receptor using structure-based three-dimensional quantitative structure-activity relationship methods
Keywords: Constitutive androstane receptor (CAR); 3D-QSAR; Drug-drug interactions (DDIs); In silico ADME; Ensemble docking; CYP2B6;
Gene-gene interactions between DRD3, MRP4 and CYP2B6 polymorphisms and its influence on the pharmacokinetic parameters of efavirenz in HIV infected patients
Keywords: Efavirenz pharmacokinetics; Genetic factors; Gene-gene interactions; CYP2B6; MRP4; DRD3;
Efavirenz pharmacogenetics in a cohort of Italian patients
Keywords: Pharmacokinetics; SNP; ABCB1; CYP2B6; HNF4α
Effect of mid-dose efavirenz concentrations and CYP2B6 genotype on viral suppression in patients on first-line antiretroviral therapy
Keywords: Virological failure; Therapeutic drug monitoring; Pharmacokinetic; Pharmacogenetic; Efavirenz; CYP2B6
Relationship between CYP2B6*6 and cold pressor pain sensitivity in opioid dependent patients on methadone maintenance therapy (MMT)
Keywords: CYP2B6; CYP2B6*6; Cold pressor test (CPT); Pain sensitivity; Methadone maintenance therapy (MMT); Opioid dependence; Male patients;
Ordered chimerogenesis applied to CYP2B P450 enzymes
Keywords: P450; CYP2B6; CYP2B11; Chimera; Cyclophosphamide; Channel;
Rifampin enhances cytochrome P450 (CYP) 2B6-mediated efavirenz 8-hydroxylation in healthy volunteers
Keywords: Rifampin; Efavirenz; 8-Hydroxylation; CYP2B6; Induction; In vivo probe;
Insights into CYP2B6-mediated drug-drug interactions
Keywords: CAR; constitutive androstane receptor; C/EBP; CCAAT/enhancer-binding protein; CHOP; cyclophosphamide-doxorubicin-vincristine-prednisone; CITCO; (6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde-O-(3,4-dichlorobenzyl)oxime); COUP-TF; chic
Association of the CYP2B6 gene with anti-tuberculosis drug-induced hepatotoxicity in a Brazilian Amazon population
Keywords: Tuberculosis; Hepatotoxicity; CYP2B6; CYP3A5
Increased prevalence of functional minor allele variants of drug metabolizing CYP2B6 and CYP2D6 genes in Roma population samples
Keywords: CYP2B6; CYP2D6; Pharmacogenetics; Roma; Hungarian
CYP2B6 poor metaboliser alleles involved in efavirenz and nevirapine metabolism: CYP2B6*9 and CYP2B6*18 distribution in HIV-exposed subjects from Dschang, Western Cameroon
Keywords: CYP2B6; Efavirenz; Nevirapine; Pharmacogenetics; Poor metabolisers; Cameroon;
Influence of HIV antiretrovirals on methadone N-demethylation and transport
Keywords: Methadone; Hepatocytes; Protease inhibitors; Cytochrome P450 3A; CYP3A; Cytochrome P450 2B6; CYP2B6;
Evaluation of metabolism dependent inhibition of CYP2B6 mediated bupropion hydroxylation in human liver microsomes by monoamine oxidase inhibitors and prediction of potential as perpetrators of drug interaction
Keywords: CYP2B6; Metabolism based inhibition; Selegiline; Drug interaction; Static model
Impact of gender on efficacy and acute toxicity of alkylating agent -based chemotherapy in Ewing sarcoma: Secondary analysis of the Euro-Ewing99-R1 trial
Keywords: Ewing sarcomas; Alkylating agent; Gender; Efficacy; Toxicity; Interaction; Metabolism; Constitutive androstane receptor; CYP3A4; CYP2B6;
CYP2B6 haplotype and biological factors responsible for hepatotoxicity in HIV-infected patients receiving efavirenz-based antiretroviral therapy
Keywords: HIV; Tuberculosis; CYP2B6; Efavirenz; Antiretroviral therapy
Effects of CYP3A5, CYP2C19, and CYP2B6 on the clinical efficacy and adverse outcomes of sibutramine therapy: A crucial role for the CYP2B6*6 allele
Keywords: CYP2B6; Polymorphisms; Sibutramine
Combining metabolomic analysis and microarray gene expression analysis in the characterization of the medicinal plant Chelidonium majus L
Keywords: Chelidonii herba; Herbal safety; Gene expression profiling; 1H-NMR fingerprint; IPA; Ingenuity pathway analysis; PCA; Principal component analysis; qRT-PCR; quantitative real-time PCR; AhRR; Aryl-hydrocarbon receptor repressor; AKR1B10; Aldo-keto reductas
MDR-1 and GST polymorphisms are involved in myelodysplasia progression
Keywords: AML; acute myeloid leukemia; CYP2B6; Cytochrome P450 2B6; del5q; 5qchrosome deletion; Gln; glutamine; GST; glutathione S-transferase; GSTM1; glutathione S-transferase Mu 1; GSTT1; glutathione S-transferase Theta 1; His; histidine; Ile; isoleucine; IPSS; i
Pharmacogenomics study in a Taiwanese methadone maintenance cohort
Keywords: Clinical Opioid Withdrawal Scale; CYP2B6; Methadone; Opioid receptors; Pharmacogenomics; Treatment Emergent Symptoms Scale
Ethanol self-administration and nicotine treatment induce brain levels of CYP2B6 and CYP2E1 in African green monkeys
Keywords: CYP2B6; CYP2E1; Nicotine; Ethanol; Monkey; Induction; BrainCYPs, cytochrome P450 enzymes; CYP2E1, cytochrome P450 2E1; CYP2B, cytochrome P450 2B; AGM, African green monkey
Correlation of CYP2B6, CYP2C19, ABCC4 and SOD2 genotype with outcomes in allogeneic blood and marrow transplant patients
Keywords: CYP2B6; CYP2C19; ABCC4; SOD2; Cyclophosphamide; Blood or marrow transplantation
Reversible time-dependent inhibition of cytochrome P450 enzymes by duloxetine and inertness of its thiophene ring towards bioactivation
Keywords: ACN; acetonitrile; APAP; acetaminophen; CYP1A2; cytochrome P450 1A2 enzyme; CYP2B6; cytochrome P450 2B6 enzyme; CYP2C19; cytochrome P450 2C19 enzyme; CYP2D6; cytochrome P450 2D6 enzyme; CYP3A4; cytochrome P450 3A4 enzyme; CYP450; cytochrome P450 enzymes;
Enantioselective capillary electrophoresis for identification and characterization of human cytochrome P450 enzymes which metabolize ketamine and norketamine in vitro
Keywords: Capillary electrophoresis; Ketamine; Norketamine; CYP3A4; CYP2A6; CYP2B6; Pharmacokinetics; Stereoselective metabolism
Endosulfan induces CYP2B6 and CYP3A4 by activating the pregnane X receptor
Keywords: Pesticide; Endosulfan; PXR; CAR; CYP3A4; CYP2B6; Human hepatocytes; HepG2 cell line
Association of CYP2B6 G15631T polymorphism with acute leukemia susceptibility
Keywords: Acute lymphoblastic leukemia; Acute myeloid leukemia; CYP2B6; Polymorphism; Pharmacogenomics; Xenobiotics
Human hepatic CYP2B6 developmental expression: The impact of age and genotype
Keywords: CYP450; Ontogeny; CYP2B6; CYP3A; Hepatic
In vitro assessment of P450 induction potential of novel chemopreventive agents SR13668, 9-cis-UAB30, and pentamethychromanol in primary cultures of human hepatocytes
Keywords: Chemoprevention; SR13668; 9-cis-UAB30; Pentamethylchromanol; Human hepatocytes; CYP1A2; CYP2B6; CYP3A4
Methadone metabolism and clearance are induced by nelfinavir despite inhibition of cytochrome P4503A (CYP3A) activity
Keywords: Methadone; Nelfinavir; CYP3A; CYP2B6; HIV; Drug interactions
Detection of ABCC2, CYP2B6 and CYP3A4 in human peripheral blood mononuclear cells using flow cytometry
Keywords: ABCC2 (MRP2); CYP2B6; CYP3A4; PBMC; Lymphocyte; Flow cytometry;
The monoterpenoids citral and geraniol are moderate inhibitors of CYP2B6 hydroxylase activity
Keywords: P450, cytochrome P450; HLM, human liver microsomes; LC/MS/MS, liquid chromatography/tandem mass spectrometryMonoterpenoids; Inhibition; CYP2B6; Bupropion; Citral; Geraniol
Regulation of CYP3A4 and CYP2B6 expression by liver X receptor agonists
Keywords: Liver X receptor agonists; Pregnane X receptor; T0901317; CYP3A4; CYP2B6; Human hepatocytes
CYP2B6 Genotype Alters Abstinence Rates in a Bupropion Smoking Cessation Trial
Keywords: Bupropion; CYP2A6; CYP2B6; genetic; nicotine; pharmacogenetic; smoking
Pharmacogenetics of antiretroviral drugs for the treatment of HIV-infected patients: An update
Keywords: Pharmacogenomics; HIV; Antiretroviral; MDR1; CYP2B6; Hypersensitivity reactions
CYP2B6 is expressed in African Green monkey brain and is induced by chronic nicotine treatment
Keywords: CYP2B6; Nicotine; Brain; Smoking; Monkey; Induction; Bupropion