دانلود مقالات ISI درباره CYP3A4، سیتوکروم P450 3A4 + ترجمه فارسی

خطوط سلولی هپاتوم انسانی در مورد داربست آلژینات فوم گازی برای آزمایشات متابولیسم درمانی و متابولیسم

Human hepatoma cell lines on gas foaming templated alginate scaffolds for in vitro drug-drug interaction and metabolism studies

Keywords: CYP3A4، سیتوکروم P450 3A4; 6β-OH-testosterone, 6β-hydroxy-testosterone; Alg-GAL, galactosilated alginate; CYP3A4, cytochrome P450 3A4; DXM, dexamethasone; GC–MS, gas-chromatography coupled to mass spectrometry; HIPF, high internal phase foam; KETO, ketoconazole; LDH, lactate dehydr

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

SUMOylation of pregnane X receptor suppresses rifampicin-induced CYP3A4 and P-gp expression and activity in LS174T cells

Keywords: CYP3A4، سیتوکروم P450 3A4; Pregnane X receptor; SUMOylation; Transcriptional activity; CYP3A4; P-gpSUMO, small ubiquitin-related modifier; PXR, pregnane X receptor; RIF, rifampicin; CYP3A4, cytochrome P450 3A4; P-gp, p-glycoprotein; MDZ, midazolam; 1′-OHMDZ, 1′-Hydroxymidazolam; Rh

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

MicroRNA-30c-1-3p is a silencer of the pregnane X receptor by targeting the 3′-untranslated region and alters the expression of its target gene cytochrome P450 3A4

Keywords: CYP3A4، سیتوکروم P450 3A4; CYP3A4, cytochrome P450 3A4; DMEM, Dulbecco's modified eagle medium; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; miR, microRNA; PXR, pregnane X receptor; RT-qPCR, reverse transcription-quantitative polymerase chain reaction; UTR, untranslated regionN

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Multiple modes of inhibition of human cytochrome P450 2J2 by dronedarone, amiodarone and their active metabolites

Keywords: CYP3A4، سیتوکروم P450 3A4; AA, arachidonic acid; ACN, acetonitrile; AF, atrial fibrillation; CYP2D6, cytochrome P450 2D6; CYP2J2, cytochrome P450 2J2; CYP3A4, cytochrome P450 3A4; CYP3A5, cytochrome P450 3A5; DDI, drug–drug interaction; EET, epoxyeicosatrienoic acid; GSH, glutathio

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Amine-free melanin-concentrating hormone receptor 1 antagonists: Novel 1-(1H-benzimidazol-6-yl)pyridin-2(1H)-one derivatives and design to avoid CYP3A4 time-dependent inhibition

Keywords: CYP3A4، سیتوکروم P450 3A4; MCH, melanin-concentrating hormone; MCHR1, melanin-concentrating hormone receptor 1; CYP3A4, cytochrome P450 3A4; TDI, time-dependent inhibition; DIO, diet-induced obesity; hERG, human ether-a-go-go related gene; DMEDA, N,N′-dimethylethylenediamine; HATU,

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2016 سفارش ترجمه

Diindolylmethane, a naturally occurring compound, induces CYP3A4 and MDR1 gene expression by activating human PXR

Keywords: CYP3A4، سیتوکروم P450 3A4; DIM, , 3,3′-diindolylmethane; PXR, pregnane X receptor; hPXR, human pregnane X receptor; mPXR, mouse pregnane X receptor; rPXR, rat pregnane X receptor; CYP, cytochrome p450; CYP3A4, cytochrome p450 3A4; MDR1, multidrug resistance protein 1; DMSO, dimethy

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Inhibitory effects of herbal constituents on P-glycoprotein in vitro and in vivo: Herb–drug interactions mediated via P-gp

Keywords: CYP3A4، سیتوکروم P450 3A4; AG, andrographolide; AP, apical; AUC, the area under the concentration–time curve; BL, basolateral; Cmax, the maximum plasma concentration; CMC, carboxymethylcellulose; CYP3A4, cytochrome P450 3A4; DAG, dehydroandrographolide; DDIs, drug–drug interactions

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Everolimus and intensive behavioral therapy in an adolescent with tuberous sclerosis complex and severe behavior ★

Keywords: CYP3A4، سیتوکروم P450 3A4; ABA, applied behavioral analysis; CYP3A4, cytochrome p450 3A4; FDA, Food and Drug Administration; SEGA, subependymal giant cell astrocytoma; mTOR, mammalian target of rapamycin; mTORC, mammalian target of rapamycin complex; TSC, tuberous sclerosis complex

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

In vivo effect of Schisandrin B on cytochrome P450 enzyme activity

Keywords: CYP3A4، سیتوکروم P450 3A4; Sch A, Schisandrin A; Sch B, Schisandrin B; SchE, Schisandra sphenanthera extract; P-gp, P-glycoprotein; MDR, multidrug resistance; CYP, cytochrome P450; CYP3A, cytochrome P450 3A; CYP3A4, cytochrome P450 3A4; IC50, the half maximal (50%) inhibitory conce

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Controlled systemic delivery by polymeric implants enhances tissue and plasma curcumin levels compared with oral administration

Keywords: CYP3A4، سیتوکروم P450 3A4; PCL-121, poly (ε-caprolactone) of 121,000 molecular weight; PEG 8K, polyethylene glycol (molecular weight 8000); CYP1A1, cytochrome P450 1A1; CYP3A4, cytochrome P450 3A4; GSTM, glutathione S-transferase (μ); PBS, phosphate-buffered-saline; BCS, bovine cal

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Identification of novel pregnane X receptor activators from traditional Chinese medicines

Keywords: CYP3A4، سیتوکروم P450 3A4; PXR, pregnane X receptor; TCM, traditional Chinese medicine; CYP3A4, cytochrome P450 3A4; DMSO, dimethylsulfoxide; RT-PCR, reverse transcriptase-polymerase chain reaction; CAR, constitutive androstane receptor; GR, glucocorticoid receptorTraditional Chine

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Effect of ethanol on spectral binding, inhibition, and activity of CYP3A4 with an antiretroviral drug nelfinavir

Keywords: CYP3A4، سیتوکروم P450 3A4; CYP3A4, cytochrome P450 3A4; CPR, cytochrome P450 reductase; b5, cytochrome b5; ART, antiretroviral therapy; NNRTIs, non-nucleoside reverse transcriptase inhibitors; PIs, protease inhibitors; 7-BFC, 7-benzyloxy-4-trifluoromethylcoumarin; 7-HFC, 7-hydroxy-

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Evidence Supports a Faster Growth Rate and/or Earlier Transformation to Clinically Significant Prostate Cancer in Black Than in White American Men, and Influences Racial Progression and Mortality Disparity

Keywords: CYP3A4، سیتوکروم P450 3A4; prostate; prostatic neoplasms; African continental ancestry group; European continental ancestry group; disease progressionAAM, black men; CXCR4, CXC chemokine receptor; CYP3A4, cytochrome P450 3A4; EAM, white men; HGPIN, high grade prostatic intraepithel

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Inhibitory effects of polyphenols on human cytochrome P450 3A4 and 2C9 activity

Keywords: CYP3A4، سیتوکروم P450 3A4; CYP, cytochrome P450; CYP2C9, cytochrome P450 2C9; CYP3A4, cytochrome P450 3A4; DIC, diclofenac; KET, ketoconazole; SPZ, sulfaphenazole; TST, testosteroneAmentoflavone; Apigenin; Cytochrome P450; Imperatorin; Polyphenols

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

A synonymous polymorphism in a common MDR1 (ABCB1) haplotype shapes protein function

Keywords: CYP3A4، سیتوکروم P450 3A4; ABC, ATP-binding cassette; ATP, adenosine triphosphate; ADP, adenosine diphosphate; CFTR, cystic fibrosis trans-membrane conductance regulator; CYP3A4, cytochrome P450 3A4; CYP3A5, cytochrome P450 3A5; IVS, intervening sequence; MDR1, multidrug resistant

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2009 سفارش ترجمه

Pharmacology of Schisandra chinensis Bail.: An overview of Russian research and uses in medicine

Keywords: CYP3A4، سیتوکروم P450 3A4; ACTH, adrenocorticotrophic hormone; ADS, astheno-depressive syndrome; ARD, acute respiratory disease; CFLF, critical frequency of light flashes; CNS, central nervous system; CYP3A4, cytochrome P450 3A4; ECG, electrocardiogram; ED, effective dose; FPS, fet

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2008 سفارش ترجمه

Mechanism-based inhibition of CYP3A4 and CYP2D6 by Indonesian medicinal plants

Keywords: CYP3A4، سیتوکروم P450 3A4; CYP, cytochrome P450; CYP3A4, cytochrome P450 3A4; CYP2D6, cytochrome P450 2D6; NADPH, nicotinamide adenine dinucleotide phosphate; HLM, human liver microsomesIndonesian medicinal plants; Mechanism-based inhibition; Cytochrome P450; CYP3A4; CYP2D6

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Pregnane X Receptor Activators Inhibit Human Hepatic Stellate Cell Transdifferentiation In Vitro

Keywords: CYP3A4، سیتوکروم P450 3A4; α-SMA, α–smooth muscle actin; cRNA, complementary RNA; CYP3A4, cytochrome P450 3A4; DMSO, dimethyl sulfoxide; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; HSC, hepatic stellate cell; IL, interleukin; PPAR, peroxisome proliferator activated receptor; P

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2006 سفارش ترجمه