دانلود مقالات ISI درباره Cyp46A1 + ترجمه فارسی

استرس اکسیداتیو و پپتید بتا آمیلوئید در بیماری آلزایمر

Oxidative stress and the amyloid beta peptide in Alzheimer's disease

Keywords: 4-HNE; 4-HydroxyNonenal; AD; Alzheimer's Disease; AICD; Amino-terminal APP Intra Cellular Domain; ApoE; Apolipoprotein E; APP; Amyloid Precursor Protein; ATP; Adenosine TriPhosphate; Aβ; Amyloid beta peptide; AβDP; Aβ-Degrading Proteases; CNS; Centra

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

کلسترول 24-هیدروکسیلاز: متابولیسم کلسترول مغزی و فراتر از آن

Cholesterol 24-hydroxylase: Brain cholesterol metabolism and beyond

Keywords: CYP46A1; Cytochrome P450; Brain cholesterol; Neuronal function; Neurodegeneration; 24 (S)-hydroxycholesterol;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2016 سفارش ترجمه

اکسسترل: تأثیر بر روی میکرو دیمن های پلاستیکی غشای پلاسما و توسعه بیماری های چشم

Oxysterols: Influence on plasma membrane rafts microdomains and development of ocular diseases

Keywords: Oxysterols; Lipid rafts; Retinopathy; Cholesterol; CYP46A1;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

اختلال متابولیسم کلسترول در بیماری هانتینگتون

The impairment of cholesterol metabolism in Huntington disease

Keywords: 24OHC; 24S-Hydroxycholesterol; 27OHC; 27-Hydroxycholesterol; ABC; ATP-binding cassette transporter; ACAT; Acyl-Coa:cholesterol acyltransferase; AD; Alzheimer disease; ApoE; Apolipoprotein E; BACHD; Bacterial artificial chromosome HD; BDNF; Brain-derived n

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

کلسترول در بیوگرافی میکولین و اختلالات هیپوومینینات

Cholesterol in myelin biogenesis and hypomyelinating disorders

Keywords: 7DHC; 7-dehydrocholesterol; ABC transporter; ATP binding cassette transporter; ApoA1; apolipoprotein A1; ApoE; apolipoprotein E; CNS; central nervous system; CYP46A1; cholesterol 24-hydroxylase; CYP51; lanosterol 14 alpha-demethylase; DHCR7; 7-dehydrochol

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

تنظیم اپی ژنتیک تشکیل اکسیسترول

Epigenetic regulation of oxysterol formation

Keywords: Cholesterol; Oxysterol; CYP46A1; CYP27A1; CYP3A4; CYP39A1; CYP7B1; CH25H; Cholesterol 7α-hydroxylase; Sterol 27-hydroxylase; Cholesterol 24-hydroxylase; Cholesterol 25-hydroxylase; Oxysterol 7α-hydroxylase; 24-hydroxycholesterol 7α-hydroxylase; Epigene

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Dietary betaine supplementation in hens modulates hypothalamic expression of cholesterol metabolic genes in F1 cockerels through modification of DNA methylation

Keywords: ACAT1; acetyl-CoA cholesterol acyltransferase 1; APOA1; apolipoprotein A1; BHMT; betaine homocysteine methyltransferase; BBB; blood brain barrier; CYP46A1; cholesterol 24-hydroxylase A 1; DNMT1; DNA methyltransferase 1; DNMT3A; DNA methyltransferase 3 A;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Part A: Temporal and dose-dependent transcriptional responses in the liver of fathead minnows following short term exposure to the polycyclic aromatic hydrocarbon phenanthrene

Keywords: SREBF1; sterol regulatory element binding transcription factor 1; FASN; fatty acid synthase; HSD17B12; hydroxysteroid (17-beta) dehydrogenase 12; ACACA; acetyl-CoA carboxylase alpha; CYB5A; cytochrome b5 type A (microsomal); SLC27A4; solute carrier family

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

CYP46A1 protects against NMDA-mediated excitotoxicity in Huntington's disease: Analysis of lipid raft content

Keywords: Excitotoxicity; CYP46A1; Huntington's disease; Lipid rafts; GluN2B; Cholesterol;

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

PPAR-γ and CYP46A1 genes polymorphism is associated with Primary Open Angle Glaucoma (POAG) in hypertensive North Indians

Keywords: POAG; Primary Open Angle Glaucoma; IOP; intraocular pressure; PPAR-γ; peroxisome proliferator-activated receptor gamma; CYP46A1; cholesterol-24S-hydroxylase; SNP; single-nucleotide polymorphism; PCR; polymerase chain reaction; RFLP; restriction fragment

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Cholesterol-metabolizing enzyme cytochrome P450 46A1 as a pharmacologic target for Alzheimer's disease

Keywords: CYP46A1; Efavirenz; Alzheimer's disease; 24-Hydroxycholesterol; Amyloid; Cholesterol;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Cholesterol metabolism and glaucoma: Modulation of Muller cell membrane organization by 24S-hydroxycholesterol

Keywords: 24S-hydroxycholesterol; Muller cells; Raft microdomain; CYP46A1; 24S-hydroxylase; DMEM; Dulbecco's modified eagle medium; ERKs ½; regulating kinases of extra-cellular signal; FBS; fetal bovine serum; GC/MS; gas chromatography/mass spectrometry; GFAP; g

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Suppression of brain cholesterol synthesis in male Mecp2-deficient mice is age dependent and not accompanied by a concurrent change in the rate of fatty acid synthesis

Keywords: 24S-OHC; 24(S)-hydroxycholesterol; Apoe; apolipoprotein E; CNS; central nervous system; Cyp27a1; cholesterol 27-hydroxylase; Cyp46a1; cholesterol 24-hydroxylase; Hmgcr; 3-hydroxy-3-methylglutaryl-CoA reductase; Mecp2; methyl CpG-binding protein 2; SC4mol;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2017 سفارش ترجمه

The association between CYP46A1 rs4900442 polymorphism and the risk of Alzheimer's disease: A meta-analysis

Keywords: Alzheimer's disease; rs4900442; CYP46A1; Meta-analysis;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Brain cortical cholesterol metabolism is highly affected by human APP overexpression in mice

Keywords: Alzheimer's disease; Aβ; Cholesterol; Amyloid precursor protein overexpression; Mouse model; APPSL; AD; Alzheimer's disease; Aβ; amyloid beta; ACAT; Acetyl-CoA acetyltransferases; APP; amyloid precursor protein; ApoB-100; apolipoprotein B-100; ApoE; apo

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2016 سفارش ترجمه

24(S)-Hydroxycholesterol induces RIPK1-dependent but MLKL-independent cell death in the absence of caspase-8

Keywords: 24S-OHC; 24(S)-hydroxycholesterol; ACAT1; acyl-CoA:cholesterol acyltransferase 1; AD; Alzheimer's disease; cIAP; cellular inhibitor of apoptosis protein; CYP46A1; cholesterol 24-hydroxylase; JurkatCas8−/−; caspase-8-deficient Jurkat; LDH; lactate de

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

New aspects of 24(S)-hydroxycholesterol in modulating neuronal cell death

Keywords: 24S-OHC; 24(S)-hydroxycholesterol; 5,6-epoxyC; cholesterol-5,6-epoxide; 7-OOHC; 7-hydroperoxycholesterol; 7-OHC; 7-hydroxycholesterol; Aβ; amyloid-β; ACAT1; acyl-CoA:cholesterol acyltransferase 1; AD; Alzheimer disease; APP; amyloid precursor protein; C

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2015 سفارش ترجمه

Oxysterols in the brain of the cholesterol 24-hydroxylase knockout mouse

Keywords: 24S-Hydroxycholesterol; 24R-Hydroxycholesterol; 24S,25-Epoxycholesterol; Oxysterol; Brain; Cyp46a1; Cyp; cytochrome P450; ESI; electrospray ionisation; FT; Fourier transform; GP; Girard P reagent; INSIG; insulin induced gene; LC; liquid chromatography; Lx

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

In vivo consequences of cholesterol-24S-hydroxylase (CYP46A1) inhibition by voriconazole on cholesterol homeostasis and function in the rat retina

Keywords: Retinal ganglion cell; Glia; Cholesterol homeostasis; CYP46A1; Voriconazole;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Inhibition and stimulation of activity of purified recombinant CYP11A1 by therapeutic agents

Keywords: Adx; adrenodoxin; Adr; adrenodoxin reductase; DLPC; dilauroylglycerol-3-phosphatidylcholine; HPCD; 2-hydroxypropyl-β-cyclodextrin; KPi; potassium phosphate; PL; phospholipid; Cytochrome P450; CYP11A1; CYP46A1; Inhibition; Activation; Drug target;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

24S-hydroxycholesterol in plasma: A marker of cholesterol turnover in neurodegenerative diseases

Keywords: LXR; Oxysterols; Dementia; Biomarker; Mass spectrometry; 24OHC; 24S-hydroxycholesterol; 27OHC; 27-hydroxycholesterol; Aβ; amyloid beta; ABC; ATP-binding cassette transporter; ACAT; acyl-Coa:cholesterol acyltransferase; AD; Alzheimer disease; Apoe; apolip

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2013 سفارش ترجمه

CYP46A1 intron-2T/C polymorphism and Alzheimer's disease: An updated meta-analysis of 16 studies including 3960 cases and 3828 controls

Keywords: Alzheimer's disease; CYP46A1; Polymorphism; Meta-analysis

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Features of the retinal environment which affect the activities and product profile of cholesterol-metabolizing cytochromes P450 CYP27A1 and CYP11A1

Keywords: CYP11A1; CYP27A1; CYP46A1; Retina; Retinal pigment epithelium; Cholesterol; 5-Cholestenoic acid; 22R-Hydroxycholesterol; Phospholipids; A2E

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Marked variability in hepatic expression of cytochromes CYP7A1 and CYP27A1 as compared to cerebral CYP46A1. Lessons from a dietary study with omega 3 fatty acids in hamsters

Keywords: Fish oil; n-3 polyunsaturated fatty acids; American Heart Association; Dietary guidelines; Cholesterol turnover; Brain; CYP7A1; CYP27A1; CYP46A1

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Transcriptional regulation of cholesterol 24-hydroxylase by histone deacetylase inhibitors

Keywords: 24S-hydroxycholesterol; CYP46A1; CYP39A1; Epigentics; Histone deacetylase inhibitor; Oxysterol; Brain cholesterol

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Combined use of mass spectrometry and heterologous expression for identification of membrane-interacting peptides in cytochrome P450 46A1 and NADPH-cytochrome P450 oxidoreductase

Keywords: CYP46A1; CPR; Crystal structure; MALDI; Membrane topology; Cholesterol; Mass spectrometry; Missed cleavage; Brain; Active site;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Oxysterols: Novel biologic roles for the 21st century

Keywords: Oxysterols; Hedgehog proteins; Fetal development; Photoxidation; Retina metabolism; CYP27A1; CYP46A1; Sulfotransferases

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه