In vivo consequences of cholesterol-24S-hydroxylase (CYP46A1) inhibition by voriconazole on cholesterol homeostasis and function in the rat retina

- Inhibition of CYP46A1 by voriconazole impairs retinal function.
- Inhibition of CYP46A1 by voriconazole activates glia in the retina.
- Inhibition of microglia by minocycline exacerbates the effects of voriconazole.