Keywords: Alarmin; Bronchial asthma; IL-33; Innate immunity; Platelets; ADP; adenosine diphosphate; AERD; aspirin-exacerbated respiratory disease; cysLT; cysteinyl leukotriene; DAMPs; danger-associated molecular patterns; EETosis; eosinophil extracellular DNA trap
مقالات ISI (ترجمه نشده)
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Keywords: RA; rheumatoid arthritis; RF; rheumatoid factor; ACPA; anti-citrullinated protein antibodies; AA; arachidonic acid; PG; prostaglandins; LT; leukotrienes; TX; thromboxanes; LX; lipoxins; NSAID; non steroidal anti-inflammatory drugs; COXIB; COX-2 selective
Keywords: CT; controlled trial; cysLT; cysteinyl leukotrienes; EAACI; European Academy of Allergy and Clinical Immunology; ECP; eosinophilic cationic protein; eNO; exhaled nitric oxide; FEV1; forced expiratory volume at one second; ITT; intention-to-treat; MS; medi
Keywords: Group 2 innate lymphoid cells; aspirin-exacerbated respiratory disease; AERD; Aspirin-exacerbated respiratory disease; CRTH2; Chemoattractant receptor-homologous molecule expressed on TH2 cells; CysLT; Cysteinyl leukotriene; ILC2; Group 2 innate lymphoid
Keywords: asthma; COPD; pulmonary fibrosis; pulmonary hypertension; ADDS; antibody-dependent degranulatory synapse; ASM; airway smooth muscle; β2-AR; β2-adrenergic receptor; Ca2+; calcium ion; CADM1; cell adhesion molecule 1; CD; cluster of differentiation; CPA3;
Keywords: AHR; airway hyper-responsiveness; BBA; bisbenzylisoquinoline alkaloid; β-hex; beta-hexosaminidase; COX; cyclooxygenase; CysLT; cysteinyl leukotriene; DNP; dinitrophenol; IgE; Immunoglobulin E; IL-(); interleukin-(); OVA; ovalbumin; PG (); prostaglandin;
Keywords: Asthma; diet; obesity; fatty acids; n-6; n-3; inflammation; resolution; AA; Arachidonic acid; AHR; Airway hyperresponsiveness; AIA; Aspirin-intolerant asthma; cLA; Conjugated linoleic acid; CRTH2/DP2; Chemoattractant receptor-homologous molecule express
Keywords: Aspirin; aspirin-exacerbated respiratory disease; asthma phenotype; latent class analysis; nonsteroidal anti-inflammatory drugs; AERD; Aspirin-exacerbated respiratory disease; cysLT; Cysteinyl leukotriene; ED; Emergency department; ICU; Intensive care uni
Leukotriene E4 induces airflow obstruction and mast cell activation through the cysteinyl leukotriene type 1 receptor
Keywords: Asthma; cysteinyl leukotrienes; receptors; bronchoconstriction; mast cells; sputum cells; leukotrienes; mass spectrometry; lipid mediators in urine; AERD; Aspirin-exacerbated respiratory disease; CysLT; Cysteinyl leukotriene; CysLT1; Cysteinyl leukotriene
Cysteinyl leukotriene receptor 1 expression identifies a subset of neutrophils during the antiviral response that contributes to postviral atopic airway disease
Keywords: Asthma; viral infection; nasal lavage; neutrophils; cysteinyl leukotrienes; BAL; Bronchoalveolar lavage; cDC; Conventional dendritic cell; CysLT; Cysteinyl leukotriene; CysLTR; Cysteinyl leukotriene receptor; FDR; False discovery rate; LT; Leukotriene; PI
Too much of a good thing: How modulating LTB4 actions restore host defense in homeostasis or disease
Keywords: LT; leukotriene; PAMP; pathogen associated molecular patterns; PRR; pattern recognition receptor; AA; arachidonic acid; LO; lipoxygenase; cPLA2; cytosolic phospholipase A2; FLAP; 5-lipoxygenase-activating protein; cysLT; cysteinyl LT; BLT; B leukotriene r
The role of cysteinyl leukotrienes and their receptors in refractory nasal polyps
Keywords: CRSw/sNP; chronic rhinosinusitis with/without nasal polyp; IL; interleukin; KCN; key cytokines negative; CysLT; cysteinyl leukotriene; CYSLTR; cysteinyl leukotriene receptor; LTRA; leukotriene receptor antagonist; FESS; functional endoscopic sinus surgery
Endogenous secreted phospholipase A2 group X regulates cysteinyl leukotrienes synthesis by human eosinophils
Keywords: Eosinophil; leukotriene; phospholipase A2; mitogen-activated kinase; asthma; allergy; 5-LO; 5-Lipoxygenase; cPLA2α; Cytosolic phospholipase A2α; CysLT; Cysteinyl leukotriene; DMSO; Dimethyl sulfoxide; ER; Endoplasmic reticulum; ERK1/2; Extracellular-sig
Schistosome infection-derived Hepatic Stellate Cells are cellular source of prostaglandin D2: Role in TGF-β-stimulated VEGF production
Keywords: COX-2; Cyclooxygenase-2; cysLT; cysteinyl-leukotriene; GM-CSF; Granulocyte-macrophage colony-stimulating factor; GR-HSCs; Hepatic Stellate Cells derived from liver granulomas of S. mansoni infected mice; HPGDS; Hematopoietic Prostaglandin D synthase; HSCs
Asthma and lower airway diseaseProstaglandin E2 inhibits mast cell-dependent bronchoconstriction in human small airways through the E prostanoid subtype 2 receptor
Keywords: Aspirin-exacerbated respiratory disease; asthma; COX products; E prostanoid receptor; explanted human tissue model; human bronchi; pharmacologic testing; prostanoid receptors; thromboxane receptor; CysLT; Cysteinyl leukotriene; DMEM; Dulbecco modified Eag
Prostaglandin D2 and leukotriene E4 synergize to stimulate diverse TH2 functions and TH2 cell/neutrophil crosstalk
Keywords: Prostaglandin D2; leukotriene E4; chemoattractant receptor-homologous molecule expressed on TH2 cells; TH2 cells; neutrophils; CAIA; Cell activation-induced aggregation; CRTH2; Chemoattractant receptor-homologous molecule expressed on TH2 cells; cysLT;
Aspirin desensitization in patients with aspirin-induced and aspirin-tolerant asthma: AÂ double-blind study
Keywords: Aspirin-induced asthma; aspirin-tolerant asthma; oral aspirin desensitization; ACQ; Asthma Control Questionnaire; AD; Aspirin desensitization; AIA; Aspirin-induced asthma; ASA; Acetylsalicylic acid; ATA; Aspirin-tolerant asthma; CT; Computed tomography; c
Prostaglandin D2 activates group 2 innate lymphoid cells through chemoattractant receptor-homologous molecule expressed on TH2 cells
Keywords: Group 2 innate lymphoid cell; PGD2; chemoattractant receptor-homologous molecule expressed on TH2 cells; IL-25; IL-33; innate type 2 immunity; adaptive type 2 immunity; CRTH2; Chemoattractant receptor-homologous molecule expressed on TH2 cells; CSF-1; Mac
Nationwide cohort study of the leukotriene receptor antagonist montelukast and incident or recurrent cardiovascular disease
Keywords: Atherosclerosis; inflammation; myocardial infarction; pharmacoepidemiology; stroke; ACE; Angiotensin-converting enzyme; ATC; Anatomical Therapeutical Chemical; COPD; Chronic obstructive pulmonary disease; CysLT; Cysteinyl leukotriene; HR; Hazard ratio; IC
Reduced expression of the prostaglandin E2 receptor E-prostanoid 2 on bronchial mucosal leukocytes in patients with aspirin-sensitive asthma
Keywords: Aspirin; prostaglandin E2, E-prostanoid receptor; asthma; AERD; Aspirin-exacerbated respiratory disease; ASA; Aspirin-sensitive asthma; BAL; Bronchoalveolar lavage; Ct; Cycle threshold; CysLT; Cysteinyl leukotriene; EP; E-prostanoid; HC; Healthy control s
Advances in mechanisms of asthma, allergy, and immunology in 2010
Keywords: Allergic conjunctivitis; allergic inflammation; anaphylaxis; asthma; asthma genetics; atopic dermatitis; cytokines; eosinophils; food allergy; immediate hypersensitivity; mast cells; nasal polyposis; polymorphisms; CSS; Churg-Strauss syndrome; cysLT; Cyst
The increasing challenge of discovering asthma drugs
Keywords: ACQ; asthma control questionnaire; AHR; airway hyper-responsiveness; AQLQ; asthma quality-of-life questionnaire; BALF; bronchoalveolar lavage fluid; bn; billion; cysLT; cysteinyl leukotrienes; DZ; dizygotic; EAR; early airway response; FDA; Food and Drug
Old and new generation lipid mediators in acute inflammation and resolution
Keywords: 5-HT; 5-hydroxytryptamine; HETEs; hydroxyeicosatetraenoic acids; 5-HEDH; 5-hydroxyeicosanoid dehydrogenase; 5(S)-HPETE; hydroperoxyeicosatetranoic acid; 15R-HETE; 15-R-hydroxyeicosatetraenoic acid; 17R-HDHA; 17R-hydroxydocosahexaenoic acid; AA; arachidoni
Asthma translational medicine: Report card
Keywords: ACQ; asthma control questionnaire; AHR; airway hyper-responsiveness; AP-1; activator protein 1; APC; antigen-presenting cell; AQLQ; asthma quality-of-life questionnaire; BALF; bronchoalveolar lavage fluid; CTLA-4; cytotoxic T lymphocyte-associated antigen
Exosomes from human macrophages and dendritic cells contain enzymes for leukotriene biosynthesis and promote granulocyte migration
Keywords: Antigen-presenting cells; eicosanoids; exosomes; inflammation; leukotrienes; TGF-β1; AA; Arachidonic acid; APC; Antigen-presenting cell; cysLT; Cysteinyl leukotriene; DC; Dendritic cell; FITC; Fluorescein isothiocyanate; FLAP; 5-Lipoxygenase-activating
Profile of eicosanoid generation in aspirin-intolerant asthma and anaphylaxis assessed by new biomarkers
Keywords: Aspirin; asthma; anaphylaxis; cysteinyl-leukotriene; 2,3-dinor-9α,11β-PGF2; ent-PGF2α, urine; AIA; Aspirin-intolerant asthma; ATA; Aspirin-tolerant asthma; CysLT; Cysteinyl leukotriene; EIA; Enzyme immunoassay; ent-PGF2α; Prostaglandin F2α enantiomer
Eoxins: AÂ new inflammatory pathway in childhood asthma
Keywords: Exhaled breath condensate; leukotrienes; 15-hydroxyeicosatetraenoic acid; eoxins; asthma; child; BAL; Bronchoalveolar lavage; BHR; Bronchial hyperresponsiveness; BMI; Body mass index; CysLT; Cysteinyl leukotriene; EBC; Exhaled breath condensate; ECP; Eosi
Leukotriene E4: Perspective on the forgotten mediator
Keywords: Cysteinyl leukotriene; leukotriene E4; asthma; aspirin-sensitive respiratory disease; cysteinyl leukotriene receptor; ASRD; Aspirin-sensitive respiratory disease; CysLT; Cysteinyl leukotriene; LT; Leukotriene; SRS-A; Slow-reacting substance of anaphylaxis
Urine Concentrations of Cysteinyl Leukotrienes in Children With Obstructive Sleep-Disordered Breathing
Keywords: adenoidal hypertrophy; cysteinyl leukotrienes; montelukast; obstructive sleep-disordered breathing; sleep apnea; tonsillar hypertrophy; BMI; body mass index; CysLT; cysteinyl leukotriene; lnCysLT; natural logarithm of cysteinyl leukotriene concentration i
Differential kinase requirement for enhancement of FcγR-mediated phagocytosis in alveolar macrophages by leukotriene B4 vs. D4
Keywords: LT; leukotriene; cysLT; cysteinyl LT; cysLT1; cysLT type 1; BLT1; BLT type 1; AM; alveolar macrophage; GPCR; G protein coupled receptor; PLC; phospholipase C; PKC; protein kinase C; ERK; extracellular related kinase 1/2; Lipid mediators; Cell signaling; P
Leukotriene Pathways and In Vitro Adenotonsillar Cell Proliferation in Children With Obstructive Sleep Apnea
Keywords: cysLT; cysteinyl leukotriene; ELISA; enzyme-linked immunosorbent assay; LT; leukotriene; OSA; obstructive sleep apnea; PBS; phosphate-buffered saline; T&A; tonsillectomy and adenoidectomy; TNF; tumor necrosis factor;
Notch signaling confers antigen-presenting cell functions on mast cells
Keywords: Mast cells; Notch; MHC class II; OX40 ligand; antigen presentation; APC; Antigen-presenting cell; BMDC; Bone marrow-derived cultured dendritic cell; BMMC; Bone marrow-derived cultured mast cell; cysLT; Cysteinyl leukotriene; DAPT; N-[N-(3,5-difluoroph
Increased urinary leukotriene E4 excretion in obstructive sleep apnea: Effects of obesity and hypoxia
Keywords: Leukotriene E4; obstructive sleep apnea syndrome; nocturnal oxygen desaturation; obesity; AHI; Apnea-hypopnea index; BMI; Body mass index; CPAP; Continuous positive air pressure; CRP; C-reactive protein; cysLT; Cysteinyl leukotriene; 11-DehydroTXB2; 11-De
Concurrent blockade of platelet-activating factor and histamine prevents life-threatening peanut-induced anaphylactic reactions
Keywords: Peanut allergy; anaphylaxis; mast cells; histamine; PAF; leukotrienes; mathematical modeling; 5-LO; 5-Lipoxygenase; AU; Area under response; cysLT; Cysteinyl leukotriene; MC; Mast cell; PA; Peanut allergy; PAF; Platelet-activating factor; PAF-R; Platelet-
Association of the cysteinyl leukotriene receptor 1 gene with atopy in the British 1958 birth cohort
Keywords: Atopy; asthma; British 1958 birth cohort; cysteinyl leukotriene receptor 1; genetics; leukotriene receptor; CysLT; Cysteinyl leukotriene; CysLTR; Cysteinyl leukotriene receptor; CYSLTR1; Cysteinyl leukotriene receptor 1 gene; LD; Linkage disequilibrium; L
Analysis of behavior-related adverse experiences in clinical trials of montelukast
Keywords: Montelukast; placebo; clinical trial; behavior; psychiatric; adverse experiences; asthma; allergic rhinitis; AE; Adverse experience; Akath-PT; Akathisia-related preferred term; BRAE; Behavior-related adverse experience; CNS; Central nervous system; CysLT1
Leukotriene D4 induces gene expression in human monocytes through cysteinyl leukotriene type I receptor
Keywords: Human monocytes; cysteinyl leukotrienes; immediate-early genes; chemotaxis; CysLT; Cysteinyl leukotriene; CysLTR1; Cysteinyl leukotriene type 1 receptor; CysLTR2; Cysteinyl leukotriene type 2 receptor; EGR; Early growth response; EGTA; Ethyleneglycol-bis-
Eicosanoid Lipid Mediators in Fibrotic Lung Diseases
Keywords: airway remodeling; leukotrienes; prostaglandins; pulmonary fibrosis; cAMP; cyclic adenosine monophosphate; cysLT; cysteinyl leukotriene; COX; cyclooxygenase; cysLT1; cysteinyl leukotriene receptor 1; EP; E prostanoid receptor; IL; interleukin; IP; I prost
12/15-Lipoxygenase deficiency protects mice from allergic airways inflammation and increases secretory IgA levels
Keywords: Asthma; allergy; inflammation; lipoxygenase; IL-13; IgA; B cells; airway; lung; AA; Arachidonic acid; APRIL; A proliferation-inducing ligand; BAFF; B cell-activating factor from the TNF superfamily; BAFF-R; BAFF receptor; BALF; Bronchoalveolar lavage fl
Role of MUC5AC in the pathogenesis of exercise-induced bronchoconstriction
Keywords: Asthma; exercise-induced bronchoconstriction; epithelial cell; goblet cell; mucin; AREG; Amphiregulin; AUC; Area under the FEV1 time curve; cysLT; Cysteinyl leukotriene; DTT; Dithiothreitol; EGF; Epidermal growth factor; EIB; Exercise-induced bronchoconst
Lipoxin A4 inhibits acute edema in mice: Implications for the anti-edematogenic mechanism induced by aspirin
Keywords: ASA; acetylsalicylic acid (aspirin); ALX-r; lipoxin receptor; ATL; aspirin-triggered lipoxin; BK; bradykinin; Boc2; butoxycarbonyl-Phe-Leu-Phe-Leu-Phe; COX-2; cyclooxygenase-2; CysLT; cysteinyl leukotriene; HTAB; hexadecyl trimethylammonium bromide; i.p.;
Leukotriene E4-induced persistent eosinophilia and airway obstruction are reversed by zafirlukast in patients with asthma
Keywords: Asthma; airways; biopsies; CysLT1 receptor; LTE4; inflammation; eosinophilia; CysLT; Cysteinyl leukotriene; 5-LO; 5-Lipoxygenase; LT; Leukotriene; Mab; Mouse monoclonal antibodies;
5-Lipoxygenase products regulate basophil functions: 5-Oxo-ETE elicits migration, and leukotriene B4 induces degranulation
Keywords: Basophils; leukotriene D4; leukotriene B4; 5-oxo-6,8,11,14-eicosatetraenoic acid; receptor; CD11b; chemotaxis; degranulation; Ca2+ influx; human; CysLT; Cysteinyl leukotriene; ED50; Median effective dose; 5-LO; 5-Lipoxygenase; LT; Leukotriene; MACS; Magne
Airway immunopathology of asthma with exercise-induced bronchoconstriction
Keywords: Asthma; exercise-induced bronchoconstriction; epithelial cell; leukotriene; prostaglandin; eosinophil; mast cell; AUC; Area under the FEV1-time curve; BHR; Bronchial hyperresponsiveness; CysLT; Cysteinyl leukotriene; EIB; Exercise-induced bronchosontricti
Cysteinyl Leukotrienes in Allergic Inflammation
Keywords: asthma; cytokines; eosinophils; inflammation; leukotrienes; leukotriene receptor antagonists; remodeling; rhinitis; AR; allergic rhinitis; AUC; area under the FEV1-vs-time curve; CysLT; cysteinyl leukotriene; GM-CSF; granulocyte-macrophage colony-stimul