Properties of dimeric, disulfide-linked rhBMP-2 recovered from E. coli derived inclusion bodies by mild extraction or chaotropic solubilization and subsequent refolding
Keywords: گره سیستین; BRE-Luc assay; Cystine-knot; Disulfide-bond; Heparin-affinity chromatography; Mild extraction; Purification; Refolding; Recombinant human bone morphogenetic protein-2;