Substituent effect of N-benzylated gramine derivatives that prevent the PP2A inhibition and dissipate the neuronal Ca2+ overload, as a multitarget strategy for the treatment of Alzheimer's disease
Keywords: Ca2 + Cytosolic; ACh; acetylcholine; AD; Alzheimer's disease; Aβ; amyloid β peptide; [Ca2+]c; cytosolic Ca2+; CALHM1; Ca2+ homeostasis modulator-1 channel; FBS; fetal bovine serum; Mem; memantine; NCLX; mitochondrial Na±/Ca2+ exchanger; NFT; neurofibrillary tangles;