دانلود مقالات ISI درباره DDR، پاسخ آسیب DNA + ترجمه فارسی

اثرات محافظتی لوپئول در برابر ژنوتوکسل ناشی از مانکوئزب در لنفوسیت های کشت شده انسان

Protective effects of lupeol against mancozeb-induced genotoxicity in cultured human lymphocytes

Keywords: DDR، پاسخ آسیب DNA; Mancozeb; Lupeol; Genotoxicity; Oxidative stress; NF-κb; Human lymphocytesCA, chromosomal aberration; MN, micronuclei; chls, cultured human lymphocytes; ROS, reactive oxygen species; DDR, DNA damage response; DMSO, dimethyl sulfoxide; PBS, phosphate buffe

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

بررسی و بهره برداری از اثرات سیستمیک از مجوز تکرار مجدد مقررات

Exploring and exploiting the systemic effects of deregulated replication licensing

Keywords: DDR، پاسخ آسیب DNA; Cdc6; Cdt1; Replication licensing factors; Replication stress; CancerRS, replication stress; DDR, DNA damage response; RLM, replication licensing machinery; pre-RC, pre-replication complex; CDK, cyclin-dependent kinase; ORC, origin recognition complex; Cd

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

شبکه زیست شناسی ردوکس در پاتوفیزیولوژی سرطان و درمان

The redox biology network in cancer pathophysiology and therapeutics

Keywords: DDR، پاسخ آسیب DNA; BER, base excision repair; CSC, cancer stem cells; DAMPs, danger-associated molecular patterns; DDR, DNA damage response; EGFR, epidermal growth factor receptor; HMGB1, high-mobility Group Box 1; HR, homologous recombination repair; IR, ionizing radiation

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

خاموش کردن ژن Che1 باعث ایجاد apoptosis سلول osteosarcoma با مهار بیان جهش p53 می شود

Che-1 gene silencing induces osteosarcoma cell apoptosis by inhibiting mutant p53 expression

Keywords: DDR، پاسخ آسیب DNA; Osteosarcoma; Che-1; Mutant p53; Cell apoptosisOS, osteosarcoma; ChIP, chromatin immunoprecipitation; AATF, apoptosis-antagonizing transcription factor; Pol II, polymerase II; DDR, DNA damage response; FBS, fetal bovine serum

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Quantitative analysis by next generation sequencing of hematopoietic stem and progenitor cells (LSK) and of splenic B cells transcriptomes from wild-type and Usp3-knockout mice

Keywords: DDR، پاسخ آسیب DNA; BM, bone marrow; DDR, DNA damage response; DUBs, deubiquitinating enzymes; HSC, hematopoietic stem cell; LSK, Lin-Sca1+ cKit+ cells; RNA-seq, RNA sequencing; Ub, ubiquitin; USP3, Ub-specific protease 3B cell; Deubiquitinating enzymes (DUBs); DNA damage re

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

PELP1: Structure, biological function and clinical significance

Keywords: DDR، پاسخ آسیب DNA; AP1, activator protein 1; AR, androgen receptor; CBP, CREB- binding protein; CDK, cyclin-dependent kinase; DDR, DNA damage response; E2F, E2F transcription factor 1; EGF, epidermal growth factor; EGFR, EGF receptor; ESR1, estrogen receptor alpha; ESR2, Es

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

DNA damage response (DDR) pathway engagement in cisplatin radiosensitization of non-small cell lung cancer

Keywords: DDR، پاسخ آسیب DNA; NSCLC, non-small cell lung cancer; CDDP, cisplatin; IR, ionizing radiation; CDDP-IR, combination treatment with cisplatin followed by ionizing radiation; DDR, DNA damage response; DSB, double strand break; NER, nucleotide excision repair; HRR, homologous

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Hydroxyurea-induced replication stress causes poly(ADP-ribose) polymerase-2 accumulation and changes its intranuclear location in root meristems of Vicia faba

Keywords: DDR، پاسخ آسیب DNA; DDR, DNA Damage Response; dNTP, deoxyribonucleoside triphosphates; DSBs, double-Strand Breaks; TEM, transmission electron microscopy; HU, hydroxyurea; NAD+, nicotinamide adenine dinucleotide; NE, nuclear envelope; NER, nucleotide excision repair; pADPRT,

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Chromatin plasticity in response to DNA damage: The shape of things to come

Keywords: DDR، پاسخ آسیب DNA; ARR, Access–Repair–Restore; ASF1, Anti-Silencing Function 1; ATP, Adenosine triphosphate; CAF-1, Chromatin Assembly Factor-1; CENPA, Centromeric Protein A; ChIP, chromatin immuno-precipitation; DDB2, DNA damage binding protein 2; DDR, DNA damage response;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

DNA damage stress induces the expression of Ribosomal Protein S27a gene in a p53-dependent manner

Keywords: DDR، پاسخ آسیب DNA; ARF, alternative reading frame; ARPP P0, acidic ribosomal phosphoprotein P0; ChIP, chromatin immunoprecipitation; DDR, DNA damage response; IHH, immortalized human hepatocyte; rDNA, ribosomal DNA; rRNA, ribosomal RNA; RPs, ribosomal proteins; RPS27a, ribo

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Tissue specific response to DNA damage: C. elegans as role model

Keywords: DDR، پاسخ آسیب DNA; BER, base excision repair; CO, crossover; DDR, DNA damage response; DSB, double strand break; FA, Fanconi anemia; GG-NER, global genome nucleotide excision repair; HR, homologous recombination; ICLR, interstrand-crosslink repair; IR, ionizing radiation; N

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

DNA damage response – A double-edged sword in cancer prevention and cancer therapy

Keywords: DDR، پاسخ آسیب DNA; DDR, DNA damage response; BER, base excision repair; MMR, mismatch repair; NER, nucleotide excision repair; TLS, translesion DNA synthesis; NHEJ, nonhomologous end joining; HR, homologous recombination; SSBs, single strand DNA breaks; DSBs, double strand

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

MKP1 phosphatase mediates G1-specific dephosphorylation of H3Serine10P in response to DNA damage

Keywords: DDR، پاسخ آسیب DNA; DDR, DNA damage response; MSK1, Mitogen and stress-activated protein kinase-1; MKP1, Mitogen-activated protein kinase phosphatase-1; ATM, Ataxia telangiectasia mutated; VEGF, Vascular endothelial growth factor; S10P, serine10 phosphorylation; IR, ionizati

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Histone markers identify the mode of action for compounds positive in the TK6 micronucleus assay

Keywords: DDR، پاسخ آسیب DNA; ATM, ataxia telangiectasia mutated; DAPI, 4′,6-diamidino-2-phenylindole; DDR, DNA damage response; DSB, double strand break; EMA, ethydium monoazide; ETO, etoposide; γH2AX, phosphorylated histone H2AX serine 139/140; IVMN, in vitro micronucleus; NOS, nosc

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Pleiotropic effects of spongean alkaloids on mechanisms of cell death, cell cycle progression and DNA damage response (DDR) of acute myeloid leukemia (AML) cells

Keywords: DDR، پاسخ آسیب DNA; DNA damage response; Cell death; Acute myeloid leukemia; Natural compounds; Spongean alkaloids; AnthrayclinesAa, aaptamine; AML, acute myeloid leukemia; Ap, aeroplysinin-1; dauno, daunorubicin; DDR, DNA damage response; H2AX, histone H2AX; γH2AX, S139-pho

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

HSP90 inhibition as a means of radiosensitizing resistant, aggressive soft tissue sarcomas

Keywords: DDR، پاسخ آسیب DNA; Soft tissue sarcoma; Radiotherapy; Radioresistance; HSP90 inhibition; RadiosensitizationATM, ataxia telangiectasia mutated; ATR, ataxia telangiectasia and RAD3 related; C12-FDG, 5-dodecanoylaminofluorescein-di-β-galactopyranoside; DDR, DNA damage response

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Enhanced susceptibility of ovaries from obese mice to 7,12-dimethylbenz[a]anthracene-induced DNA damage

Keywords: DDR، پاسخ آسیب DNA; DMBA, 7,12-dimethylbenz[a]anthracene; DDR, DNA damage response; DSBs, double-strand breaks; NHEJ, Non-Homologous End Joining; HR, Homologous Recombination; TLR, Toll like receptor; Cyp, cytochromes p450; IGF, insulin growth factor; PI3K, phosphatidylinosi

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Loss of HuR leads to senescence-like cytokine induction in rodent fibroblasts by activating NF-κB

Keywords: DDR، پاسخ آسیب DNA; SASP, senescence-associated secretory phenotype; HuR, human antigen R; IL-6, interleukin 6; MEF, mouse embryonic fibroblast; sh-RNA, short hairpin RNA; DDR, DNA damage response; IR, ionizing radiation; UV, ultravioletSenescence; SASP; HuR; NF-κB

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

p53-Dependent suppression of genome instability in germ cells

Keywords: DDR، پاسخ آسیب DNA; Medaka fish; Microsatellite instability; Radiation; Spermatogonial stem cell; msh2; p53CE, fluorescent capillary electrophoresis; DDR, DNA damage response; DSB, double-strand break; ESTR, expanded simple tandem repeat; HRM, high-resolution melting; MMR, m

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Neurodegeneration-associated instability of ribosomal DNA

Keywords: DDR، پاسخ آسیب DNA; ALB, albumin; AD, Alzheimer's disease; CpG, cytosine–phosphate–guanine; DLB, dementia with Lewy bodies; DDR, DNA damage response; HR, homologous recombination; tRNAK-ctt, lysine-ctt tRNA; MCI, mild cognitive impairment; MMSE, Minimental State Examination;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

IGFBP-3: A cell fate pivot in cancer and disease

Keywords: DDR، پاسخ آسیب DNA; DNA-PK, deoxyribonucleic acid-protein kinase; DDR, DNA damage response; DSB, double-strand breaks; ER, Endoplasmic reticulum; IGF, insulin-like growth factor; IGFBP-3, insulin-like growth factor binding protein-3; IGF1R, insulin-like growth factor recepto

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Chromatin structure and radiation-induced DNA damage: From structural biology to radiobiology

Keywords: DDR، پاسخ آسیب DNA; Chromatin; Nucleosome; DNA damage; Radiation; RadiobiologyAR, adaptive response; BD, base damage; bp, base pair; CT, computed tomography [or] chromosome territory; DDR, DNA damage response; DSB, double strand break; FISH, fluorescence in situ hybridizatio

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Targeting the nucleolus for cancer intervention

Keywords: DDR، پاسخ آسیب DNA; DDR, DNA Damage Response; DSB, Double Stranded Break; IR, Ionizing Radiation; NAD, Nucleolus Associated Domain; NCL, Nucleolin; NOR, Nucleolar Organizer Region; NPM, Nucleophosmin; PIC, Pre-Initiation Complex; Pol I, DNA-dependent RNA Polymerase I; Pol II

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2014 سفارش ترجمه

Modulators of cellular senescence: mechanisms, promises, and challenges from in vitro studies with dietary bioactive compounds

Keywords: DDR، پاسخ آسیب DNA; AMPK, adenosine monophosphate–activated protein kinase; CS, cellular senescence; Cu, copper; DDR, DNA damage response; EGCG, epigallocatechin gallate; hF, human fibroblasts; hTERT, human telomerase reverse transcriptase; IL-1β, interleukin-1 beta; mTOR, m

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2014 سفارش ترجمه

Protective role of the endoplasmic reticulum protein mitsugumin23 against ultraviolet C-induced cell death

Keywords: DDR، پاسخ آسیب DNA; 7-AAD, 7-aminoactinomycin D; DDR, DNA damage response; DSBs, double-strand breaks; EGFP, enhanced green fluorescent protein; Etop, etoposide; HEK293T, human embryonic kidney 293T; Iv, insertless vector; MEFs, murine embryonic fibroblasts; RT-PCR, reverse

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Parg deficiency confers radio-sensitization through enhanced cell death in mouse ES cells exposed to various forms of ionizing radiation

Keywords: DDR، پاسخ آسیب DNA; Parg, poly(ADP-ribose) glycohydrolase; LET, linear-energy-transfer; Parp-1, poly(ADP-ribose) polymerase 1; PAR, poly(ADP-ribose); γ-H2AX, phosphorylated H2AX; DDR, DNA damage response; SSB, single strand break; DSB, double strand break; PAR, poly(ADP-ribo

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Increased Cdc7 expression is a marker of oral squamous cell carcinoma and overexpression of Cdc7 contributes to the resistance to DNA-damaging agents

Keywords: DDR، پاسخ آسیب DNA; DDK, Dbf4-dependent kinase; DDR, DNA damage response; OSCC, oral squamous cell carcinoma; IHC, immunohistochemistry; HU, hydroxyurea; CPT, camptothecin; CI, confidence interval; HR, hazard ratios; TUNEL, terminal deoxynucleotidyl transferase-mediated dUTP

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Alteration of the DNA damage response in colorectal tumor progression

Keywords: DDR، پاسخ آسیب DNA; DSB(s), DNA double-strand break(s); DDR, DNA damage response; 53BP1, p53-binding protein 1; LI, labeling indexColorectal carcinoma; Double-strand breaks; DNA damage response; γH2AX; p53-binding protein 1

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Long non-coding RNA ANRIL (CDKN2B-AS) is induced by the ATM-E2F1 signaling pathway

Keywords: DDR، پاسخ آسیب DNA; DDR, DNA damage response; hnRNP-K, heterogeneous nuclear ribonucleoprotein K; PTEN, phosphatase and tensin homolog; PTENP1, PTEN pseudogene 1; PI3K, phosphatidylinositide 3-kinases; CTNNB1, cadherin-associated protein β1; INK4, inhibitors of CDK4Long non-

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Tools and strategies for DNA damage interactome analysis

Keywords: DDR، پاسخ آسیب DNA; DDR, DNA damage response; DIGE, differential in-gel electrophoresis; DPC, DNA-protein crosslink; EMSA, electrophoretic mobility shift assay; ESI-MS/MS, electrospray ionisation tandem mass spectrometry; FRET, fluorescence resonance energy transfer; IRIF, i

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Dimerization, but not phosphothreonine binding, is conserved between the forkhead-associated domains of Drosophila MU2 and human MDC1

Keywords: DDR، پاسخ آسیب DNA; MU2, mutator 2; MDC1, mediator of DNA damage checkpoint protein 1; FHA, forkhead-associated; DDR, DNA damage response; DSB, double-strand breakX-ray crystallography; DNA damage response; Forkhead-associated domain; MDC1; Molecular evolution

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

RAD18–BRCTx interaction is required for efficient repair of UV-induced DNA damage

Keywords: DDR، پاسخ آسیب DNA; BRCT, BRCA1 carboxyl-terminal; DDR, DNA damage response; HRR, homologous recombination repair; IRIF, ionizing radiation-induced foci; MEFs, mouse embryonic fibroblasts; PRR, postreplication repair; PCNA, proliferating cell nuclear antigen; SFB, S-protein,

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

SIRT1 as a therapeutic target in inflammaging of the pulmonary disease

Keywords: DDR، پاسخ آسیب DNA; AICAR, 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside; AMPK, AMP-activated kinase; ATM, ataxia telangiectasia mutated; CHK2, checkpoint kinase 2; COPD, chronic obstructive pulmonary disease; DDR, DNA damage response; DSB, double-strand break; EGCG, e

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Quantitative phosphoproteomics to characterize signaling networks

Keywords: DDR، پاسخ آسیب DNA; AT1R, angiotensin II type 1A receptor; cAMP, cyclic AMP; CXCR, C-X-C chemokine receptor; DDR, DNA damage response; EGFR, epidermal growth factor receptor; ESC, embryonic stem cell; GPCR, G-protein coupled receptors; IMAC, immobilized metal affinity chroma

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Differential function of NBS1 and ATR in neurogenesis

Keywords: DDR، پاسخ آسیب DNA; DDR, DNA damage response; DSB, DNA double-strand breaks; SSB, DNA single-strand breaks; MRN, MRE11/RAD50/NBS1 complex; CNS, central nervous system; VZ, ventricular zone; SVZ, subventricular zone; GL, granule layer; ML, molecular layer; MEF, mouse embryoni

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Small molecule inhibitor of the RPA70 N-terminal protein interaction domain discovered using in silico and in vitro methods

Keywords: DDR، پاسخ آسیب DNA; Replication Protein A; Inhibitors; High-throughput screen; EMSA; DockingDNA, deoxyribonucleic acid; DDR, DNA damage response; BER, base excision repair; HRR, homologous recombination repair; SMI, small molecule inhibitor; RPA, Replication Protein A; kDa,

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Epigenetic alterations associated with cellular senescence: A barrier against tumorigenesis or a red carpet for cancer?

Keywords: DDR، پاسخ آسیب DNA; HC, heterochromatin; SAHF, senescence-associated heterochromatin foci; OIS, oncogene-induced senescence; DDR, DNA damage response; HMT, histone methyltransferase; HDM, histone demethylase; HDAC, histone deacetylase; ROS, reactive oxygen species; DNMT, DNA

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Dynamics of the transcriptome response of cultured human embryonic stem cells to ionizing radiation exposure

Keywords: DDR، پاسخ آسیب DNA; hESC, human embryonic stem cell; IR, ionizing radiation; DDR, DNA damage response; PBS, phosphate buffer saline; BSA, bovine serum albumin; PI, propidium iodide; SAM, Significance Analysis of Microarrays; FDR, false discovery rate; GO, Gene Ontology; DNA

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

The DNA damage checkpoint allows recombination between divergent DNA sequences in budding yeast

Keywords: DDR، پاسخ آسیب DNA; DDR, DNA damage response; SSA, single-strand annealing; DSB, double-strand break; BIR, break-induced replication; HR, homologous recombination; ssDNA, single-stranded DNA; NHEJ, non-homologous end joining; SDSA, synthesis-dependent strand annealing; TLS,

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Mevalonate pathway inhibitors affect anticancer drug-induced cell death and DNA damage response of human sarcoma cells

Keywords: DDR، پاسخ آسیب DNA; Mevalonate pathway; Small GTPases; Anticancer drugs; DNA damage response (DDR); Sarcoma cellsATM, ataxia telangiectasia mutated; ATR, ATM and Rad3-related; Chk, checkpoint kinase; DDR, DNA damage response; ERK, extracellular regulated kinase; H2AX, histon

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Poly(ADP-ribosyl)ation affects stabilization of Che-1 protein in response to DNA damage

Keywords: DDR، پاسخ آسیب DNA; 3-ABA, 3-aminobenzamide; A-T, ataxia-telangiectasia; ATM, ataxia telangiectasia mutated; DDR, DNA damage response; Doxo, doxorubicin; DSB, double strand break; MEF, mouse embryonic fibroblasts; PAR, polymers of ADP-ribose; PARG, poly(ADP-ribose) glycohydr

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

M2, a novel anthracenedione, elicits a potent DNA damage response that can be subverted through checkpoint kinase inhibition to generate mitotic catastrophe

Keywords: DDR، پاسخ آسیب DNA; AN-9, pivaloyloxymethyl butyrate; ATM, ataxia telangiectasia mutated; ATR, ataxia telangiectasia mutated-related; CC, closed; Chk1, checkpoint kinase 1; Chk2, checkpoint kinase 2; CI, combination index; DDR, DNA damage response; DNA-PK, DNA protein kinase

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2011 سفارش ترجمه

At the stem of youth and health

Keywords: DDR، پاسخ آسیب DNA; AGE, advanced glycation end product; CDKI, cyclin-dependent kinase inhibitor; CR, caloric restriction; DDR, DNA damage response; DNMT, DNA methyltransferases; DSB, double-strand breaks; eNOS, endothelial Nitric Oxide Synthase; eNoSC, energy-dependent nucl

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2011 سفارش ترجمه

Anticancer drug 5-fluorouracil induces reproductive and developmental defects in Caenorhabditis elegans

Keywords: DDR، پاسخ آسیب DNA; 5-FU, 5-fluorouracil; AO, acridine orange; BER, base excision repair; DAPI, 4′6-diamidino-2-phenylindole; DDR, DNA damage response; DPD, dihydropyrimidine dehydrogenase; FdUMP, fluorodeoxyuridine monophosphate; FdUTP, fluorodeoxyuridine triphosphate; FUMP

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Fine tuning chemotherapy to match BRCA1 status

Keywords: DDR، پاسخ آسیب DNA; DDR, DNA damage response; DSB, double stranded break; HR, homologous recombination; NER, nucleotide excision repair; NHEJ, non-homologous end joining; NSCLC, non-small cell lung carcinoma; PARP, poly ADP ribose polymerase; siRNA, small interfering RNA; SS

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

3rd US–EU Workshop: Systems level understanding of DNA damage responses

Keywords: DDR، پاسخ آسیب DNA; AT, ataxia telangiectasia; ATM, Ataxia telangiectasia mutated; ATR, ataxia telangiectasia related; CC, catalytic core; DBD, DNA binding domain; DDR, DNA damage response; DSB, double strand break; HR, homologous recombination; HRD, HR-defective; MEF, mouse

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Oxidation in the nucleotide pool, the DNA damage response and cellular senescence: Defective bricks build a defective house

Keywords: DDR، پاسخ آسیب DNA; 8-oxo-dG, 8-oxo-7,8-dihydro-2′-deoxyguanosine; 8-oxoG, 8-oxoguanine; BER, base excision repair; DDR, DNA damage response; dNTP, deoxyribonucleotide triphosphate; DSB, DNA double-strand break; ETC, electron transport chain; hTERT, human telomeric reverse t

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Sirt1 physically interacts with Tip60 and negatively regulates Tip60-mediated acetylation of H2AX

Keywords: DDR، پاسخ آسیب DNA; DDR, DNA damage response; DSB, DNA double-strand break; IRIF, irradiation-induced foci; γIR, γ-ray irradiationSirt1; Tip60; H2AX; IR-induced foci (IRIF)

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Expression of DNA damage response genes indicate progressive breast tumors

Keywords: DDR، پاسخ آسیب DNA; DDR, DNA damage response; ER, estrogen receptor; PR, progesterone receptorBreast Cancer; DNA damage response; Transcript level; Real-time PCR; Western

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Nucleotide excision repair and the degradation of RNA pol II by the Caenorhabditis elegans XPA and Rsp5 orthologues, RAD-3 and WWP-1

Keywords: DDR، پاسخ آسیب DNA; AMA-1, C. elegans large subunit RNA polymerase; C. elegans, Caenorhabditis elegans; CS, Cockayne syndrome; DDR, DNA damage response; NER, nucleotide excision repair; ROS, reactive oxygen species; UV, ultraviolet; XP, xeroderma pigmentosumxpa-1; rad-3; Rsp

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2008 سفارش ترجمه