Lipid raft: A floating island of death or survival
Keywords: گیرنده مرگ; Lipid raft; Cholesterol; Death receptor; Kinase; Calcium channel; Apoptosis
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Peroxisome proliferator-activated receptor-γ cross-regulation of signaling events implicated in liver fibrogenesis
Keywords: گیرنده مرگ; AdipoR; adiponectin receptor; AMPK; 5â²-AMP-activated protein kinase; AP1; activator protein 1; C/EBP; CCAAT/enhancer binding protein; CHB; chronic hepatitis B; Cidea; mitochondrial cell death-inducing DNA fragmentation factor α-like effector A; CTGF; c
Anti-cancer effect of bee venom toxin and melittin in ovarian cancer cells through induction of death receptors and inhibition of JAK2/STAT3 pathway
Keywords: گیرنده مرگ; Bee venom; Ovarian cancer; Death receptor; JAK/STAT3
Glutathione and modulation of cell apoptosis
Keywords: گیرنده مرگ; âΨ; mitochondrial membrane potential; ANT; adenine nucleotide translocase; Apaf-1; apoptotic protease-activating factor-1; ASK-1; apoptosis signal-regulating kinase-1; ATO; arsenic trioxide; AVD; apoptotic volume decrease; BSO; l-buthionine (S,R)-sulfo
Apigenin induces apoptosis via tumor necrosis factor receptor- and Bcl-2-mediated pathway and enhances susceptibility of head and neck squamous cell carcinoma to 5-fluorouracil and cisplatin
Keywords: گیرنده مرگ; 5-Fu; 5-fluorouracil; EGFR; epidermal growth factor receptor; HNSCC; human head and neck squamous cell carcinoma; NF-κB; nuclear transcription factor kappa B; ROS; reactive oxygen species; TNF-R; tumor necrosis factor receptor; TRAIL-R; TNF-related apopt
The proteasome inhibitor MG132 potentiates TRAIL receptor agonist-induced apoptosis by stabilizing tBid and Bik in human head and neck squamous cell carcinoma cells
Keywords: گیرنده مرگ; TRAIL; tumor necrosis factor-related apoptosis inducing ligand; DR; death receptor; HNSCC; head and neck squamous cell carcinoma; MOMP; mitochondrial outer membrane permeabilization; mAb; monoclonal antibody; CI; combination index.; TRAIL receptors; Prote
Impact of death receptor signaling on the malignancy of pancreatic ductal adenocarcinoma
Keywords: گیرنده مرگ; Cancer of the pancreas; PDAC; Apoptosis; Death receptor; TNF; TRAIL; CD95L; Signal transduction
Treatment of small cell lung cancer with TRA-8 in combination with cisplatin and radiation
Keywords: گیرنده مرگ; Small Cell; Anti-DR5; Cisplatin; Radiation; Death receptor;
Dual role of NO donors in the reversal of tumor cell resistance and EMT: Downregulation of the NF-κB/Snail/YY1/RKIP circuitry
Keywords: گیرنده مرگ; Bcl-xL; B-cell leukemia-xL; CDDP; cis-diammine-dichloro-platinum; DETANONOate; (Z)-1-[2-(2-aminoethyl)-N-(2-ammonio-ethyl) amino] diazen-1-ium-1, 2-diolate; DHMEQ; dehydroxymethylepoxyquinomicin; DR; death receptor; ERK; extracellular signal-regulated kin
Apoptosis-induced changes in mitochondrial lipids
Keywords: گیرنده مرگ; Mitochondria; Cardiolipin; Lysophosphatidyl-choline; MOMP; Bid; Bcl-2; Death receptor; Apoptosis; Membrane lipids;
Piceatannol enhances TRAIL-induced apoptosis in human leukemia THP-1 cells through Sp1- and ERK-dependent DR5 up-regulation
Keywords: گیرنده مرگ; Piceatannol; TRAIL; Death receptor; Sp1; ERK;
Research ArticleHIV infection increases HCV-induced hepatocyte apoptosis
Keywords: گیرنده مرگ; HCV-HIV coinfection; Apoptosis; TRAIL receptor; JFH-1; Japanese Fulminant Hepatitis 1; TRAIL; TNF-related apoptosis-inducing ligand; PARP; poly (ADP-ribose)polymerase; TGF-β1; transforming growth factor beta1; DR4; Death receptor 4; DR5; death receptor
Pathways of macrophage apoptosis within the interface membrane in aseptic loosening of prostheses
Keywords: گیرنده مرگ; Wear debris; Death receptor; Endoplasmic reticulum stress apoptosis; Macrophage
Diosgenin induces death receptor-5 through activation of p38 pathway and promotes TRAIL-induced apoptosis in colon cancer cells
Keywords: گیرنده مرگ; Colon cancer cells; Diosgenin; Death receptor; TRAIL; p38 MAPK; ApoptosisTRAIL, the tumor necrosis factor (TNF) α-related apoptosis-inducing ligand; DR, death receptor; MAPK, mitogen activated protein kinase; COX-2, cyclooxygenase-2
Oxaliplatin Sensitizes Human Colon Cancer Cells to TRAIL Through JNK-Dependent Phosphorylation of Bcl-xL
Keywords: گیرنده مرگ; Chemotherapy; Cell Death; Kinase; Colorectal Cancer Therapy; DR; death receptor; EV; empty vector; IC50; median inhibitory concentration; JNK; c-Jun N-terminal kinase; PI; propidium iodide; siRNA; small interfering RNA; S62; serine 62; S62A; serine 62 ala
The synthesized novel fluorinated compound (LJJ-10) induces death receptor- and mitochondria-dependent apoptotic cell death in the human osteogenic sarcoma U-2 OS cells
Keywords: گیرنده مرگ; 6-Fluoro-2-(3-fluorophenyl)-4-substituted anilinoquinazoline derivatives; LJJ-10; U-2 OS cells; Death receptor; Mitochondrial apoptotic signaling
Seleno-cyclodextrin sensitises human breast cancer cells to TRAIL-induced apoptosis through DR5 induction and NF-κB suppression
Keywords: گیرنده مرگ; Seleno-cyclodextrin; TRAIL; Apoptosis; Death receptor; Nuclear factor-κB;
Lactobacillus strains induce TRAIL production and facilitate natural killer activity against cancer cells
Keywords: گیرنده مرگ; TRAIL; tumor necrosis factor-related apoptosis-inducing ligand; PBMC; peripheral blood mononuclear cells; DR; death receptor; DcR; decoy receptor; GAPDH; glycerlaldehyde-3-phosphate dehydrogenase; GMFI; geometric mean fluorescence intensity; TRAIL; Cancer
Up-regulation of death receptor 4 and 5 by celastrol enhances the anti-cancer activity of TRAIL/Apo-2L
Keywords: گیرنده مرگ; TRAIL/APO-2L, the tumor necrosis factor (TNF) α–related apoptosis-inducing ligand; PI, propidium iodide; PBS, phosphate buffer saline; DR, Death receptor; MAPK, mitogen activated protein kinasesCelastrol; Death receptor; TRAIL/Apo-2L; Apoptosis; Anti-canc
Lipid raft connection between extrinsic and intrinsic apoptotic pathways
Keywords: گیرنده مرگ; APAF-1; apoptotic protease-activating factor-1; CASMER; clusters of apoptotic signaling molecule-enriched rafts; CTx; cholera toxin; DiOC6(3); 3,3â²-dihexyloxacarbocyanine iodide; DR4; death receptor 4; DR5; death receptor 5; DISC; death-inducing signali
2(±)-7,8,3â²,4â²,5â²-pentamethoxyflavan induces G2/M phase arrest and apoptosis in HL60 cells
Keywords: گیرنده مرگ; Flavan; G2/M arrest; Apoptosis; Death receptor; Mitochondria;
Hypoxia/reoxygenation up-regulates death receptor expression and enhances apoptosis in human biliary epithelial cells
Keywords: گیرنده مرگ; Hypoxia/reoxygenation; Death receptor; TRAIL; Apoptosis; Biliary cells
Functional analysis of the posttranslational modifications of the death receptor 6
Keywords: گیرنده مرگ; Death receptor; TNFRSF21; Glycosylation; Palmitoylation; Lipid rafts
Molecular targeted therapies for pancreatic cancer
Keywords: گیرنده مرگ; Death receptor; Epidermal growth factor receptor; Molecular targeted therapy; Pancreatic cancer; Vascular endothelial growth factor
TL1A (TNFSF15) Regulates the Development of Chronic Colitis by Modulating Both T-Helper 1 and T-Helper 17 Activation
Keywords: گیرنده مرگ; APC; antigen-presenting cell; DC; dendritic cell; DR; death receptor; DSS; dextran sodium sulfate; GALT; gut-associated lymphoid tissue; IFN; interferon; IL; interleukin; IL-23R; interleukin-23 receptor; LP; lamina propria; mAb; monoclonal antibody; MLN;
Normal levels of constitutive and death receptor-mediated apoptosis of peripheral blood neutrophils from patients with chronic idiopathic neutropenia
Keywords: گیرنده مرگ; Apoptosis; Caspase; Chronic idiopathic neutropenia; Death receptor; Granulocyte colony-stimulating factor; Neutrophil; Phosphatidylserine externalization;
Induction of apoptosis by tumor suppressor FHIT via death receptor signaling pathway in human lung cancer cells
Keywords: گیرنده مرگ; FHIT; Tumor suppressor; Apoptosis; Death receptor; Caspase; Lung cancer
Sensitization of chronic lymphocytic leukemia cells to TRAIL-induced apoptosis by hyperthermia
Keywords: گیرنده مرگ; TRAIL; TNF-related apoptosis inducing ligand; CLL; chronic lymphocytic leukemia; DR; death receptor; FADD; Fas associated death domain; DISC; death signaling inducing complex; FlipL; long forms of FADD-like ICE inhibitory protein; TNF; tumor necrosis fact
Molecular effectors of multiple cell death pathways initiated by photodynamic therapy
Keywords: گیرنده مرگ; 1O2; singlet oxygen; ÎÏm; mitochondrial transmembrane potential; [Ca2+]cyt; cytosolic Ca2+-concentration; AlPc; aluminum phthalocyanine; ALA; 5-aminolevulinic acid; AIF; apoptosis inducing factor; ANT; adenine nucleotide translocator; Apaf-1; apoptosis
Anti-tumor activity of TRA-8 anti-death receptor 5 (DR5) monoclonal antibody in combination with chemotherapy and radiation therapy in a cervical cancer model
Keywords: گیرنده مرگ; Apoptosis; Cervical cancer; Death receptor; Mononclonal antibodies; Chemoradiation
p73 induces apoptosis by different mechanisms
Keywords: گیرنده مرگ; p53; p63; p73; Apoptosis; Cell death; DNA damage; Scotin; PUMA; Bax; CD95; Death receptor; Cancer;
The sunburn cell: Regulation of death and survival of the keratinocyte
Keywords: گیرنده مرگ; Sunburn cell; Keratinocyte; UVB; Apoptosis; Survival; p53; MAPK; Death receptor; Apoptosome;
Characterisation of monoclonal antibodies to the TNF and TNF receptor families
Keywords: گیرنده مرگ; DcR; Decoy receptor; DR; death receptor; TRAIL; TNF related apoptosis inducing ligand; APRIL; a proliferation inducing ligand; BAFF; B cell activating factor of the TNF family; BAFF-R; BAFF receptor; BCMA; B cell maturation antigen; TACI; transmembrane ac
Cocaine-induced changes in the expression of apoptosis-related genes in the fetal mouse cerebral wall
Keywords: گیرنده مرگ; Frontal lobe; Occipital lobe; Death receptor; Mitochondria; Caspases; DNA microarray;
Interactive Effects of HDAC Inhibitors and TRAIL on Apoptosis Are Associated with Changes in Mitochondrial Functions and Expressions of Cell Cycle Regulatory Genes in Multiple Myeloma
Keywords: گیرنده مرگ; TRAIL/Apo-2L; apoptosis; histone deacetylase inhibitor; multiple myeloma; death receptors; DR; death receptor; DcR; decoy receptor; HDAC; histone deacetylase; IAP; inhibitor of apoptosis protein; PARP; poly(ADP-ribose) polymerase; SAHA; suberoylanilide hy
Involvement of death receptor signaling in mechanical stretch-induced cardiomyocyte apoptosis
Keywords: گیرنده مرگ; Mechanical stretch; Death receptor; FADD; Apoptosis; Cardiomyocyte;