
BIIB021, a synthetic Hsp90 inhibitor, induces mutant ataxin-1 degradation through the activation of heat shock factor 1
Keywords: 17-AAG; 17-allylamino-17-demethoxygeldanamycin; ALP; autophagy-lysosome pathway; AR; androgen receptor; ATXN1; ataxin-1; DMSO; dimethyl sulfoxide; DRPLA; dentatorubral pallidoluysian atrophy; HD; Huntington's disease; HSE; heat shock element; HSF1; heat