Keywords: GPCR; Ubiquitination; Deubiquitination; TLR4/CD14; Lung injury
مقالات ISI (ترجمه نشده)
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Keywords: AFC; 7-amino-4-trifluoro-methylcoumarin; CoV; coronavirus; DUB; deubiquitination; MERS; Middle East respiratory syndrome; 6MP; 6-mercaptopurine; NEM; N-ethylmaleimide; PLpro; papain-like protease; SARS; severe acute respiratory syndrome; 6TG; 6-thioguanin
Biochemical properties of K11,48-branched ubiquitin chains
Keywords: Post-translational modification; Ubiquitination; K11,48-branched chains; Affinity; Deubiquitination; Native chemical ligation of peptide hydrazine;
USP22 promotes resistance to EGFR-TKIs by preventing ubiquitination-mediated EGFR degradation in EGFR-mutant lung adenocarcinoma
Keywords: USP22; Deubiquitination; EGFR degradation; EGFR-TKIs resistance; EGFR-mutant lung adenocarcinoma;
Disulfiram can inhibit MERS and SARS coronavirus papain-like proteases via different modes
Keywords: MERS- and SARS-CoV; Papain-like protease; Disulfiram; 6-Thioguanine; Mycophenolic acid; Synergistic inhibition; CoV; coronavirus; Mpro; main protease; DDC; diethyldithiolcarbamate; DUB; deubiquitination; MERS; Middle East respiratory syndrome; βME; β-me
USP10 suppresses tumor progression by inhibiting mTOR activation in hepatocellular carcinoma
Keywords: HCC; USP10; Deubiquitination; mTOR;
ReviewThe emerging roles of the ubiquitination/deubiquitination system in tumor radioresistance regarding DNA damage responses, cell cycle regulation, hypoxic responses, and antioxidant properties: Insight into the development of novel radiosensitizing st
Keywords: Ubiquitination; Deubiquitination; Cancer cell; Radiosensitivity; Radioresistance;
Ubiquitin C-terminal hydrolase-L3 promotes interferon antiviral activity by stabilizing type I-interferon receptor
Keywords: UCHL3; Deubiquitination; SCFβâTrCP; Interferon; Antiviral response;
USP3 stabilizes p53 protein through its deubiquitinase activity
Keywords: USP3; p53; Deubiquitination; Cell proliferation; Cell transformation;
Possible roles of the transcription factor Nrf1 (NFE2L1) in neural homeostasis by regulating the gene expression of deubiquitinating enzymes
Keywords: Proteostasis; Ubiquitination; Deubiquitination; Neurodegeneration; Gene regulation; ARE; antioxidant response element; CNC; Cap'n'Collar; DUB; deubiquitinating enzyme; Nrf1; NF-E2-related factor 1; NFE2L1; NF-E2-like 1; qRT-PCR; quantitative real time- PC
Deubiquitinases and cancer: A snapshot
Keywords: Deubiquitinases; Ubiquitination; Cancer; Deubiquitination; DUBs; DUBs inhibitors;
Molecular hydrogen inhibits lipopolysaccharide-triggered NLRP3 inflammasome activation in macrophages by targeting the mitochondrial reactive oxygen species
Keywords: ATP; adenosine triphosphate; IL-1β; interleukin-1 beta; LPS; lipopolysaccharide; mtDNA; mitochondrial DNA; mtROS; mitochondrial reactive oxygen species; NLRP3; NOD like receptor family pyrin domain-containing 3; TLR4; toll-like receptor 4; 8-OHdG; 8-hydr
Structure of USP7 catalytic domain and three Ubl-domains reveals a connector α-helix with regulatory role
Keywords: Ubiquitin conjugation; Deubiquitination; USP7; Helix stability;
The role of deubiquitinating enzymes in chromatin regulation
Keywords: Cell cycle; Chromatin; Deubiquitination; Histones; Transcriptional regulationUb, ubiquitin; DUBs, deubiquitinating enzymes; OTUs, ovarian tumor proteases; MJDs, Josephin or Machado-Joseph disease protein domain proteases; JAMMs, Jab1/MPN domain-associated
USP15 stabilizes the transcription factor Nrf1 in the nucleus, promoting the proteasome gene expression
Keywords: Ubiquitination; Deubiquitination; Proteasomal degradation; Transcription factor; Gene regulation; ARE; antioxidant response element; CNC; Cap'n'Collar; DUB; deubiquitinating enzyme; ER; endoplasmic reticulum; NHB1; N-terminal homology box 1; Nrf1; NF-
Ubiquitin-specific Protease-7 Inhibition Impairs Tip60-dependent Foxp3Â + T-regulatory Cell Function and Promotes Antitumor Immunity
Keywords: Immuno-oncology; Anti-tumor immunity; T-regulatory cells; Deubiquitination;
The emerging role of deubiquitination in nucleotide excision repair
Keywords: UV; ultraviolet; NER; nucleotide excision repair; TC-NER; transcription coupled NER; GG-NER; global genome NER; XPC; xeroderma pigmentosum complementation group C; UV-DDB DUB; deubiquitinating enzyme; CS; cockayne syndrome; CSA; cockayne syndrome protein
Regulation of peroxisomal matrix protein import by ubiquitination
Keywords: AAA; ATPase associated with diverse cellular activities; APEM9; aberrant peroxisome morphology 9; HECT; homologous to the E6-AP carboxyl-terminus; PTS; peroxisomal targeting sequence; RBR ligase; RING-between-RING ligase; RING; really interesting new gene
Yersinia YopJ negatively regulates IRF3-mediated antibacterial response through disruption of STING-mediated cytosolic DNA signaling
Keywords: BMDMs; bone marrow-derived macrophages; c-di-GMP; cyclic diguanylate monophosphate; DMEM; Dulbecco's modified Eagle's medium; ER; endoplasmic reticulum; FBS; fetal bovine serum; GST; Glutathione S-transferase; HEK293T; human embryonic kidney; IB; immunobl
USP22 acts as an oncogene by regulating the stability of cyclooxygenase-2 in non-small cell lung cancer
Keywords: Ubiquitin-specific protease 22; Cyclooxygenase-2; Non-small cell lung cancer; Prostaglandin E2; Deubiquitination;
The deubiquitinating enzyme UBPy/USP8 interacts with TrkA and inhibits neuronal differentiation in PC12 cells
Keywords: TrkA; USP8/UBPy; Deubiquitination; Signaling endosomes; Differentiation; PC12 cells;
Cylindromatosis (CYLD) inhibits Streptococcus pneumonia-induced plasminogen activator inhibitor-1 expression via interacting with TRAF-6
Keywords: Streptococcus pneumoniae; PAI-1; Cyindromatosis (CYLD); TRAF-6; Deubiquitination;
Deubiquitination and stabilization of T-bet by USP10
Keywords: T-bet; USP10; Deubiquitination; Quercetin; Inflammation;
The Usp8 deubiquitination enzyme is post-translationally modified by tyrosine and serine phosphorylation
Keywords: Usp8; Ubiquitination; Deubiquitination; EGFR; Tyrosine phosphorylation; Serine phosphorylation;
Molecular mechanisms and functions of cytokine-inducible deubiquitinating enzymes
Keywords: Cytokine-inducible; Deubiquitination; Leukemia; Ubiquitin; Ubiquitination
Nonenzymatic assembly of branched polyubiquitin chains for structural and biochemical studies
Keywords: Ubiquitin; Polyubiquitin; Branched chain; Isopeptide bond; Unnatural amino acids; Deubiquitination
Ubiquitination and deubiquitination of REST and its roles in cancers
Keywords: REST; Ubiquitination; Deubiquitination; Neural stem cell; Tumorigenesis;
Differential domain structure stability of the severe acute respiratory syndrome coronavirus papain-like protease
Keywords: Viral protease; Deubiquitination; Reversible three-state unfolding; Molten globule; Analytical ultracentrifugation;
Roles of ubiquitin signaling in transcription regulation
Keywords: Ubiquitination; Deubiquitination; Transcription; Histone; p53; Myc; RNA polymerase; Ubiquitin
Ubiquitin C-terminal hydrolase-L3 regulates Smad1 ubiquitination and osteoblast differentiation
Keywords: Uch-L3; Smad1; Deubiquitination; Osteoblast differentiation
A novel small molecule deubiquitinase inhibitor blocks Jak2 signaling through Jak2 ubiquitination
Keywords: DUB; deubiquitinase; NEM; N-ethylmaleimide; Jak/Stat inhibitor; Deubiquitination; Signal transduction; Aggresome;
ERBB2 is a target for USP8-mediated deubiquitination
Keywords: Ubiquitination; Deubiquitination; Usp8; Cbl; Receptor tyrosine kinases;
Proteins that bind to IKKγ (NEMO) and down-regulate the activation of NF-κB
Keywords: IKKγ; NEMO; NF-κB; Ubiquitination; Deubiquitination;
C-terminal region of USP7/HAUSP is critical for deubiquitination activity and contains a second mdm2/p53 binding site
Keywords: USP7; HAUSP; mdm2; p53; Deubiquitination; Second binding site
Regulation of the epithelial sodium channel (ENaC) by membrane trafficking
Keywords: ENaC trafficking; Clathrin-mediated endocytosis; Rab proteins; Deubiquitination; Vesicle recycling
Negative regulation of Toll-like receptor signaling pathway
Keywords: TLR; Negative regulation; Degradation; Deubiquitination
Deubiquitination of Chfr, a checkpoint protein, by USP7/HAUSP regulates its stability and activity
Keywords: Chfr; USP7; HAUSP; Ubiquitination; Deubiquitination; Mass spectrometry
The expression of Usp42 during embryogenesis and spermatogenesis in mouse
Keywords: Deubiquitination; Embryogenesis; Protein degradation; Spermatogenesis; Ubiquitin specific protease
A substrate for deubiquitinating enzymes based on time-resolved fluorescence resonance energy transfer between terbium and yellow fluorescent protein
Keywords: Green fluorescent protein; Deubiquitination; TR-FRET
Selectivity in ISG15 and ubiquitin recognition by the SARS coronavirus papain-like protease
Keywords: Severe acute respiratory syndrome; Coronavirus; Papain-like protease; Deubiquitination; Ubiquitin; ISG15; Specificity
Functional properties of CYLD
Keywords: CYLD; Cylindromatosis; Deubiquitination; NF-κB
14-3-3-dependent inhibition of the deubiquitinating activity of UBPY and its cancellation in the M phase
Keywords: 14-3-3; Cell division; Deubiquitination; Deubiquitinating enzyme; Endosome; M phase; Phosphorylation; Ubiquitin
STAM-AMSH interaction facilitates the deubiquitination activity in the C-terminal AMSH
Keywords: AMSH; Deubiquitination; Isopeptidase; Lysine-63 link; Metalloprotease; Multivesicular body pathway; SH3 domain; Signal transduction; STAM; Ubiquitin;
The expression patterns of deubiquitinating enzymes, USP22 and Usp22
Keywords: Deubiquitinating enzyme; Deubiquitination; DUB; Gene expression; In situ hybridization; Mouse embryonic stage; Ubiquitination; USP22
Deubiquitinating enzyme USP36 contains the PEST motif and is polyubiquitinated
Keywords: Deubiquitination; HeLa DUB-1; PEST; Protein degradation; Ubiquitination; USP36;
Deubiquitination by proteasome is coordinated with substrate translocation for proteolysis in vivo
Keywords: Deubiquitination; Proteolysis; Substrate;