دانلود مقالات ISI درباره بی رحم + ترجمه فارسی

هدف قرار دادن مسیرهای مولکولی در سلول های بنیادی سرطانی با ترکیبات طبیعی زیست فعال

Targeting molecular pathways in cancer stem cells by natural bioactive compounds

Keywords: بی رحم; 5-FU; 5-Fluorouracil; ABCB5; ATP-binding cassette sub-family B member 5; ABCC2; ATP-binding cassette sub-family C member 2; ABCG2; ATP-binding cassette sub-family G member 2; ACs; Anthocyanins; ALDH; aldehyde dehydrogenase; AML; acute myeloid leukemia; AP

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2018 سفارش ترجمه

بیان و اهمیت ریزش مو در گلیوم انسان

The expression and significance of dishevelled in human glioma

Keywords: بی رحم; Glioma; Dishevelled; β-catenin; Proliferation; Invasion

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Extract from Butea monosperma inhibits β-catenin/Tcf signaling in SW480 human colon cancer cells

Keywords: بی رحم; CRC; colorectal cancer; NBF-BMFE; n-butanol fraction of B. monosperma flower extract; APC; adenomatous polyposis coli; GSK-3β; glycogen synthase kinase 3β; CK1; casein kinase 1; LRP5/6; low density lipoprotein receptor- related protein; Dvl; dishevelled

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Cftr Modulates Wnt/β-Catenin Signaling and Stem Cell Proliferation in Murine Intestine

Keywords: بی رحم; Cystic Fibrosis; Dishevelled; Organoids; Intracellular pH; Neoplasia; CBC; crypt-base columnar cell; CCH; carbachol; CF; cystic fibrosis; Cftr; cystic fibrosis transmembrane conductance regulator; DEP; Dishevelled, Egl-10, and Pleckstrin; Dvl; Dishevelled

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2018 سفارش ترجمه

Hsa-miR-11181 regulates Wnt signaling pathway through targeting of APC2 transcripts in SW480 cell line

Keywords: بی رحم; Wnt; wingless-type; APC; adenomatosis polyposis coli; Axin; axis inhibition protein; FZ; frizzled; LEF; lymphoid enhancer binding factor; TCF; T-cell-specific factor; GSK3-β; glycogen synthase kinase 3-beta; TRE; transcriptional response element; Dsh; di

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2018 سفارش ترجمه

A promising natural product, pristimerin, results in cytotoxicity against breast cancer stem cells in vitro and xenografts in vivo through apoptosis and an incomplete autopaghy in breast cancer

Keywords: بی رحم; 7-AAD; 7-amino-actinomycin D; ABC; ATP-binding cassette; AEC; 3-amino-9-ethyl carbazole; ATD; acute toxicity determination; Atg5; autophagy protein 5; ATP; adenosine-5′-triphosphate; BCL-2; B-cell lymphoma 2; Bip/GRP78; binding immunoglobulin protein/78

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

The ciliary protein Rpgrip1l in development and disease

Keywords: بی رحم; BB; Basal body; Bbs; Bardet-Biedl syndrome; C. elegans; Caenorhabditis elegans; CC; Coiled-Coil; Cep290; Centrosomal Protein 290; COACH; Cerebellar Vermis Aplasia Oligophrenia Congenital Ataxia Coloboma Hepatic Fibrosis; CRD; Cone Rod Dystrophy; Cux1; Cut

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

Emerging role and therapeutic implication of Wnt signaling pathways in liver fibrosis

Keywords: بی رحم; α-SMA; α-smooth muscle actin; ALD; alcoholic liver disease; APC; adenomatous polyposis coli; CamKII; calcium sensitive enzymes calmodulin kinase II; CK1; casein kinase 1; CLD; chronic liver disease; COX-2; cyclooxygenase-2; CTGF; connective tissue growt

دانلود رایگان متن کامل مقاله ISI 73 صفحه سال انتشار : 2018 سفارش ترجمه

The origins of rimmed vacuoles and granulovacuolar degeneration bodies are associated with the Wnt signaling pathway

Keywords: بی رحم; AD; Alzheimer's disease; APC; adenomatous polyposis coli; Arf6; ADP-ribosylation factor 6; CK1δ; casein kinase 1δ; Dvl; dishevelled; GSK-3β; glycogen-synthase kinase 3β; GVD; granulovacuolar degeneration; Hsp70; heat shock protein 70; Lrp4; low dens

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Molecular basis for the regulation of the circadian clock kinases CK1δ and CK1ε

Keywords: بی رحم; ATP; adenosine triphosphate; CK1; casein kinase 1; CK2; casein kinase 2; CTD; C-terminal domain; TTFL; transcriptional and translational feedback loop; GSK-3β; glycogen synthase kinase 3β; MEFs; mouse embryonic fibroblast cells; ConA; concanavalin A; LP

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

FZD10-Gα13 signalling axis points to a role of FZD10 in CNS angiogenesis

Keywords: بی رحم; DMR; dynamic mass redistribution; DVL; dishevelled; dcFRAP; dual color fluorescence recovery after photobleaching; FRET; Förster resonance energy transfer; FZD; Frizzled; WNT; Wingless/Int-1 family of proteins; LRP5/6; Low Density Lipoprotein Receptor-Re

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Complexity of the Wnt/β‑catenin pathway: Searching for an activation model

Keywords: بی رحم; APC; adenomatous polyposis coli; BCL-9; B-cell lymphoma 9; BMPs; bone morphogenetic proteins; CARM; coactivator-associated arginine methyltransferase; CBP; CREB-binding protein; CK1α; casein kinase 1α; CRD; Cysteine-Rich Domain; DIX; Dishevelled interac

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Targeting of CXXC5 by a Competing Peptide Stimulates Hair Regrowth and Wound-Induced Hair Neogenesis

Keywords: بی رحم; AGA; androgenetic alopecia; ALP; alkaline phosphatase; DBM; Dvl-binding motif; DHT; dihydrotestosterone; Dvl; Dishevelled; HFDPC; human hair follicle dermal papilla cell; PCNA; proliferating cell nuclear antigen; PTD; protein transduction domain; VPA; val

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2017 سفارش ترجمه

Dishevelled stability is positively regulated by PKCζ-mediated phosphorylation induced by Wnt agonists

Keywords: بی رحم; Dishevelled; Atypical protein kinase C ζ; Dvl phosphorylation; Dvl stability; Wnt signaling;

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2017 سفارش ترجمه

Redox signaling in the gastrointestinal tract

Keywords: بی رحم; HNE; 4-hydroxynonenal; 8-OHdG; 8-oxo-7,8-dihydro-2′-deoxyguanosine; AP-1; Activator protein 1; APC; Adenomatous polyposis coli; APE-1; Apurinic/apyrimidinic endonuclease 1; Math1; Atonal homolog 1; Bax; BCL2-associated X protein; β-TrCP; Beta-transduci

دانلود رایگان متن کامل مقاله ISI 150 صفحه سال انتشار : 2017 سفارش ترجمه

Identification of small-molecule compounds targeting the dishevelled PDZ domain by virtual screening and binding studies

Keywords: بی رحم; Dishevelled; PDZ domain; Pharmacophore; Wnt; Virtual screening; Docking; Surface plasmon resonance; Fluorescence spectroscopy;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

APPL1 endocytic adaptor as a fine tuner of Dvl2-induced transcription

Keywords: بی رحم; AP-1; activating protein 1; APPL; adaptor protein containing pleckstrin homology domain, phosphotyrosine binding domain and leucine zipper motif; CKI; casein kinase I; Dvl; Dishevelled; GST; glutathione S-transferase; JNK; c-Jun N-terminal kinase; LRP; lo

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Structure-activity studies of Wnt/β-catenin inhibition in the Niclosamide chemotype: Identification of derivatives with improved drug exposure

Keywords: بی رحم; APC; adenomatous polyposis coli; CRC; colorectal cancer; Dvl; Dishevelled; LEF/TCF; lymphoid enhancer factor/T cell factor; Fzd1; Frizzled1; GFP; green fluorescent protein; NAFLD; non-alcoholic fatty liver disease; NASH; non-alcoholic steatohepatitis; SAR

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

NKD1 marks intestinal and liver tumors linked to aberrant Wnt signaling

Keywords: بی رحم; APC; adenomatous polyposis coli; BAC; bacterial artificial chromosome; CBC; crypt base columnar; Cp; crossing point; CRC; colorectal carcinoma; CTNNB1; the β-CATENIN gene; Dvl; dishevelled; EGFP; enhanced green fluorescent protein; EphB2; ephrin type-B r

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Selective multifaceted E3 ubiquitin ligases barricade extreme defense: Potential therapeutic targets for neurodegeneration and ageing

Keywords: بی رحم; AAD; active adenylation domain; 4-PBA; 4-phenylbutyric acid; 6-OHDA; 6-hydroxydopamine; ABCG5/8; ATP-binding cassette sub-family G member 5/8; AD; Alzheimer's disease; AIB1; amplified in breast cancer 1; AIP4; atrophin-1 interacting protein 4; AMPA; α-

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2015 سفارش ترجمه

Retinoic acid negatively regulates dact3b expression in the hindbrain of zebrafish embryos

Keywords: بی رحم; Dact; Dishevelled; Wnt signaling; Retinoic acid signaling; Vertebrate development;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

NEDD4L regulates convergent extension movements in Xenopus embryos via Disheveled-mediated non-canonical Wnt signaling

Keywords: بی رحم; NEDD4L; Dishevelled; Convergent-extension

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Small molecule modulators of Wnt/β-catenin signaling

Keywords: بی رحم; APC; adenomatous polyposis coli; CRC; colorectal cancer; Dvl; dishevelled; LEF/TCF; lymphoid enhancer factor/T cell factor; Fzd1; Frizzled1; GFP; green fluorescent protein; GSK3; glycogen synthase kinase 3; SAR; structure-activity relationships; Wnt sig

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

The distribution of Dishevelled in convergently extending mesoderm

Keywords: بی رحم; Planar cell polarity; Dishevelled; Xenopus; Convergent extension; Localisation; Image analysis; QuimP;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

A Gene Expression Signature of Epithelial Tubulogenesis and a Role for ASPM in Pancreatic Tumor Progression

Keywords: بی رحم; Pancreatic Cancer; Tumor Progression; Prognostic Factor; Biomarker; ASPM; abnormal spindle-like microcephaly associated; C-index; concordance index; CSC; cancer stem cell; 3D; 3-dimensional; Dvl; dishevelled; HPDE; human pancreatic ductal epithelial; PDAC

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

C. elegans fmi-1/flamingo and Wnt pathway components interact genetically to control the anteroposterior neurite growth of the VD GABAergic neurons

Keywords: بی رحم; Flamingo; Axon guidance; Neurite growth; Anterior/posterior patterning; Wnt; Frizzled; Dishevelled;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Adenosine A1 receptor stimulation enhances osteogenic differentiation of human dental pulp-derived mesenchymal stem cells via WNT signaling

Keywords: بی رحم; ADA; adenosine deaminase; A1R; adenosine A1 receptors; A2AR; adenosine A2A receptors; A2BR; adenosine A2B receptors; A3R; adenosine A3 receptors; ALP; alkaline phosphatase; ARS; Alizarin Red S staining; CCPA; 2-chloro-N6-cyclopentyladenosine; CGS21680; 2-

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

Frizzled7 as an emerging target for cancer therapy

Keywords: بی رحم; ALL; Acute lymphoblastic leukemia; APC; Adenomatous polyposis coli; CamKII; Calmodulin kinase II; Cthrc1; Collagen triple helix repeat containing protein; CK1; Caseine kinase 1; CTNNB1; β-catenin gene; CRD; Cysteine rich domain; CSC; Cancer stem cells; D

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

The selenoproteins GPx2, TrxR2 and TrxR3 are regulated by Wnt signalling in the intestinal epithelium

Keywords: بی رحم; GPx; glutathione peroxidase; TrxR; thioredoxin reductase; Gsk3β; glycogen synthase kinase 3β; APC; adenomatous polyposis coli; Dvl; dishevelled; Lgr5; leucine-rich repeat containing G protein-coupled receptor 5; Lrp; low density lipoprotein receptor-rel

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

RACK1 Suppresses Gastric Tumorigenesis by Stabilizing the β-Catenin Destruction Complex

Keywords: بی رحم; Dvl2; Tumor Suppressor; GNB2L1; Stomach Cancer; Dvl; Dishevelled; LRP; low-density lipoprotein receptor-related protein; MO; morpholino nucleotides; PKC; protein kinase C; RACK1; receptor for activated protein kinase C;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2012 سفارش ترجمه

Research ArticlePharmacological inhibition of Frizzled-7 displays anti-tumor properties in hepatocellular carcinoma

Keywords: بی رحم; HCC; hepatocellular carcinoma; FZD7; Frizzled-7; JNK; c-jun NH2-terminal kinase; PKC; protein kinase C; DVL; dishevelled; PDZ; postsynaptic density protein (PSD)-95, Discs-large and ZO-1; RHPD; Rhodamine-tagged Heptapeptide Protein transduction domain for

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

The expression and distribution of Wnt and Wnt receptor mRNAs during early sea urchin development

Keywords: بی رحم; Axis specification; Polarity; Early patterning; Wnt signaling; Wnt; Frizzled; LRP6; β-Catenin; Dishevelled; Maternal mRNA; Sea urchin; Protein degradation; Micromeres

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Dishevelled-DEP domain interacting protein (DDIP) inhibits Wnt signaling by promoting TCF4 degradation and disrupting the TCF4/β-catenin complex

Keywords: بی رحم; DDIP; Dishevelled; TCF4/β-catenin complex; Proteasome;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Dishevelled: The hub of Wnt signaling

Keywords: بی رحم; Dishevelled; Wnt; β-catenin; Planar cell polarity; Development

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Prickle promotes neurite outgrowth via the Dishevelled dependent pathway in C1300 cells

Keywords: بی رحم; Neurite-like process formation; Prickle; Dishevelled; PCP; Retinoic acid

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

The N- or C-terminal domains of DSH-2 can activate the C. elegans Wnt/β-catenin asymmetry pathway

Keywords: بی رحم; C. elegans; Dishevelled; Morphogenesis;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

CWN-1 functions with DSH-2 to regulate C. elegans asymmetric neuroblast division in a β-catenin independent Wnt pathway

Keywords: بی رحم; C. elegans; Dishevelled; Wnt; Asymmetric neuroblast division;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2009 سفارش ترجمه

Indole-2-amide based biochemical antagonist of Dishevelled PDZ domain interaction down-regulates Dishevelled-driven Tcf transcriptional activity

Keywords: بی رحم; Dishevelled; Tcf; PDZ domain; Wnt; Indole; Anti-cancer; Apoptosis

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2008 سفارش ترجمه

Dishevelled-induced phosphorylation regulates membrane localization of Par1b

Keywords: بی رحم; Par1; Dishevelled; Wnt; Microtubule; Polarity

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Drosophila Naked cuticle (Nkd) engages the nuclear import adaptor Importin-α3 to antagonize Wnt/β-catenin signaling

Keywords: بی رحم; Wnt; Wingless; Naked cuticle; Dishevelled; Importin-α3; Nuclear transport

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

Wnt-3a utilizes a novel low dose and rapid pathway that does not require casein kinase 1-mediated phosphorylation of Dvl to activate β-catenin

Keywords: بی رحم; Wnt-3a; Dishevelled; Dopaminergic cells; Casein kinase 1; Activation of β-catenin; Canonical Wnt signalling

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Dishevelled proteins regulate cell adhesion in mouse blastocyst and serve to monitor changes in Wnt signaling

Keywords: بی رحم; Dishevelled; Mouse; Blastocyst; Preimplantation; Development;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Asymmetric localizations of LIN-17/Fz and MIG-5/Dsh are involved in the asymmetric B cell division in C. elegans

Keywords: بی رحم; LIN-17; MIG-5; Asymmetric localization; Frizzled; Dishevelled; C. elegans; PCP

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

Differential activities of the core planar polarity proteins during Drosophila wing patterning

Keywords: بی رحم; Planar polarity; PCP; Drosophila; Frizzled; Strabismus; Flamingo; Dishevelled; Prickle; Diego;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2007 سفارش ترجمه

Frizzled-7 turnover at the plasma membrane is regulated by cell density and the Ca2+-dependent protease calpain-1

Keywords: بی رحم; EC; endothelial cell(s); BAEC; bovine aortic endothelial cell(s); HUVEC; human umbilical vein endothelial cell; HEK293 cells; human embryonic kidney 293 cells; TCF; T-cell factor; Fz; Frizzled; LRP; low density lipoprotein-related receptor protein; ER; en

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2007 سفارش ترجمه

Analysis of dishevelled localization and function in the early sea urchin embryo

Keywords: بی رحم; Dishevelled; DIX domain; Wnt signalling; Beta-catenin; Axis specification; Early petterning; Sea urchin embryo; Animal-vegetal axis

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2007 سفارش ترجمه

Cell-autonomous, myristyl-independent activity of the Drosophila Wnt/Wingless antagonist Naked cuticle (Nkd)

Keywords: بی رحم; Wnt; Wingless; Naked cuticle; Dishevelled; Signal transduction; Drosophila;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2007 سفارش ترجمه

Asymmetric developmental potential along the animal–vegetal axis in the anthozoan cnidarian, Nematostella vectensis, is mediated by Dishevelled

Keywords: بی رحم; Axial properties; Polarity; Cnidaria; Anthozoa; Nematostella vectensis; Dishevelled; Wnt; β-Catenin

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2007 سفارش ترجمه

Zebrafish Naked1 and Naked2 antagonize both canonical and non-canonical Wnt signaling

Keywords: بی رحم; Naked cuticle; Planar cell polarity; Silberblick; Bozozok; Wnt11; Wnt8; Dishevelled; β-Catenin

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2007 سفارش ترجمه

Wnt-dependent spindle polarization in the early C. elegans embryo

Keywords: بی رحم; Wnt signaling; C. elegans; Spindle polarity; Asymmetric cell division; Dishevelled

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه