دانلود مقالات ISI درباره DKO، دو شکست ناپذیر + ترجمه فارسی

گلیوز بیفزیک، نوروپاتولوژی را در یک مدل موس موسوم به سندوف کنترل می کند

Bi-phasic gliosis drives neuropathology in a Sandhoff disease mouse model

Keywords: DKO، دو شکست ناپذیر; AMPAR, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; CNS, central nervous system; DKO, double knockout; GFAP, glial fibrillary acidic protein; IL-6, interleukin-6; NF-L, neurofilament-L; PBMC, peripheral blood mononuclear cells; PSD-95, p

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Single administration of a novel γ-secretase modulator ameliorates cognitive dysfunction in aged C57BL/6J mice

Keywords: DKO، دو شکست ناپذیر; Aβ, β-amyloid; ACSF, artificial cerebrospinal fluid; AD, Alzheimer׳s disease; APP, amyloid precursor protein; Ca2+, calcium ion; CTF, C terminal fragment; DKO, double knockout; DMSO, dimethyl sulfoxide; ER, endoplasmic reticulum; FAD, familial early-onset

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Methylation-dependent and independent regulatory regions in the Na,K-ATPase alpha4 (Atp1a4) gene may impact its testis-specific expression

Keywords: DKO، دو شکست ناپذیر; bp, base pair; CGI, CpG island; CMV, human cytomegalovirus; Dnmt, DNA methyltransferase; DMEM, Dulbecco's Modified Eagle's media; DKO, double knockout; ES cell, mouse embryonic stem cell; FBS, fetal bovine serum; HB-EGF-C, C-terminal fragment of heparin-b

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Murine CD8+ T cells but not macrophages express the vitamin D 1α-hydroxylase

Keywords: DKO، دو شکست ناپذیر; 1,25(OH)2D3, 1,25-dihydroxyvitamin D3; 25(OH)D3, 25-hydroxyvitamin D3; BM, bone marrow; BMDM, bone marrow derived macrophages; BW, body weight; Cyp, Cyp27B1; DSS, dextran sodium sulfate; DKO, double knockout; gal, galactosidase; IFN, interferon; KO, knock

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

CYP26B1 promotes male germ cell differentiation by suppressing STRA8-dependent meiotic and STRA8-independent mitotic pathways

Keywords: DKO، دو شکست ناپذیر; BrdU, 5-bromo-2′-deoxyuridine; Cyp26b1, cytochrome P450 b261; dKO, double knockout; E, embryonic day; ES, embryonic stem; Fgf9, fibroblast growth factor 9; IHC, immunohistochemistry; KO, knockout; RA, retinoic acid; RAR, retinoic acid receptor; PBS, phosp

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Phospholipase C-β in immune cells

Keywords: DKO، دو شکست ناپذیر; BCR, B cell receptor; CT, C-terminal; DAG, diacylglycerol; dko, double knockout; GAP, GTPase-activating protein; GPCR, G-protein-coupled receptor; HSC, hematopoietic stem cell; IL, interleukin; IP3, inositol 1,4,5-trisphosphate; ITAM, immunoreceptor tyros

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Loss of PHLPP protects against colitis by inhibiting intestinal epithelial cell apoptosis

Keywords: DKO، دو شکست ناپذیر; CRC, colorectal cancer; DKO, double knockout; IBD, inflammatory bowel disease; IEC, intestine epithelial cell; IHC, immunohistochemistry; PHLPP, PH domain Leucine-rich-repeats Protein Phosphatase; PI3K, phosphoinositide 3-kinase; UC, ulcerative colitisPHL

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

TNFR1 signaling kinetics: Spatiotemporal control of three phases of IKK activation by posttranslational modification

Keywords: DKO، دو شکست ناپذیر; ASK1, apoptosis signal-regulating kinase 1; cFLIP, cellular caspase-8 (FLICE)-like inhibitory protein; cIAP1, cellular inhibitor of apoptosis 1; DICS, death-inducing signaling complex; DKO, double knockout; FADD, Fas-associated death domain; IκB, inhibito

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Type I Interferons Maintain Foxp3 Expression and T-Regulatory Cell Functions Under Inflammatory Conditions in Mice

Keywords: DKO، دو شکست ناپذیر; Adoptive Transfer; Inflammatory Bowel Disease; Mouse Model; Immune RegulationBrdU, bromodeoxyuridine; DAI, Disease Activity Index; DKO, double knockout; ELISA, enzyme-linked immunosorbent assay; FACS, fluorescence-activated cell sorted; HPRT, hypoxanthine

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

A Feedback Loop Between the Liver-Enriched Transcription Factor Network and Mir-122 Controls Hepatocyte Differentiation

Keywords: DKO، دو شکست ناپذیر; Liver Development; Gene Regulatory Network; Biliary Hyperplasia; EmbryonicAlb, albumin; Apo, apolipoprotein; BMEL, bipotential murine embryonic liver; ChIP-Seq, chromatin immunoprecipitation/ultra-high throughput sequencing; dKO, double knockout; E, embry

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Small heat shock proteins in redox metabolism: Implications for cardiovascular diseases

Keywords: DKO، دو شکست ناپذیر; AF, atrial fibrillation; CHF, congestive heart failure; CryAB, αB-crystallin; DKO, double knockout; DOXO, doxorubicin; Evo-Devo, evolutionary developmental biology; EST, expressed sequence tag; G6PD, glucose 6-phosphate dehydrogenase; GSH, glutathione; GP

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

Genetic deletion of regulator of G-protein signaling 4 (RGS4) rescues a subset of fragile X related phenotypes in the FMR1 knockout mouse

Keywords: DKO، دو شکست ناپذیر; dKO, double knockout; FMRP, fragile X mental retardation protein; FXS, fragile X syndrome; GAP, GTPase activating protein; GIRK, G-protein coupled inwardly rectifying K+ channel; GPCR, G-protein coupled receptor; KO, knockout; mGluR, metabotropic glutamat

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Granzyme B contributes to extracellular matrix remodeling and skin aging in apolipoprotein E knockout mice

Keywords: DKO، دو شکست ناپذیر; apoE, apolipoprotein E; KO, knockout; DKO, double knockout; ECM, extracellular matrix; GrB, granzyme B; UV, ultraviolet; SHG, second harmonic generationApolipoprotein E; Skin; Aging; Diet; Granzyme B; Decorin

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Molecular disruptions of the panglial syncytium block potassium siphoning and axonal saltatory conduction: pertinence to neuromyelitis optica and other demyelinating diseases of the central nervous system

Keywords: DKO، دو شکست ناپذیر; aquaporin4 (AQP4); connexin; freeze-fracture replica immunogold labeling (FRIL); gap junction; Kir4.1; NaV1AQP4, aquaporin-4; cdKO, conditional double-knockout; CMTX, Charcot–Marie–Tooth disease; CNS, central nervous system; dKO, double knockout; FRIL, fr

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2010 سفارش ترجمه

The importance of synapsin I and II for neurotransmitter levels and vesicular storage in cholinergic, glutamatergic and GABAergic nerve terminals

Keywords: DKO، دو شکست ناپذیر; ACh, acetylcholine; ChAT, choline acetyltransferase; DKO, double knockout; GAD, glutamic acid decarboxylase; PCA, perchloric acid; SDS, sodium dodecyl sulphate; SV2A, synaptic vesicle protein 2A; VAChT, vesicular acetylcholine transporter; VGAT, vesicular

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Structural and functional link between the mitochondrial network and the endoplasmic reticulum

Keywords: DKO، دو شکست ناپذیر; Ca2+, calcium ions; [Ca2+], Ca2+ concentration; [Ca2+]c, cytosolic Ca2+ concentration; [Ca2+]ER, resting concentration of ER Ca2+; [Ca2+]m, mitochondrial Ca2+ concentration; DKO, double knockout; EM, electron microscopy; ER, endoplasmic reticulum; ERAD, e

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Disturbances in the secretion of neurotransmitters in IA-2/IA-2β null mice: Changes in behavior, learning and lifespan

Keywords: DKO، دو شکست ناپذیر; IA-2; IA-2β; secretory vesicles; behaviorANOVA, analysis of variance; CTA, conditioned-taste aversion; DCV, dense core secretory vesicles; DKO, double knockout; FSH, follicular stimulating hormone; HPLC, high-performance liquid chromatography; IA-2, islet

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Synapsin-dependent development of glutamatergic synaptic vesicles and presynaptic plasticity in postnatal mouse brain

Keywords: DKO، دو شکست ناپذیر; gene knockout; synaptogenesis; facilitation; delayed response enhancement; vesicular transporter; Schaffer collateralACSF, artificial cerebrospinal fluid; DKO, double knockout; DRE, delayed response enhancement; fEPSP, field excitatory postsynaptic potent

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

EphB2 and EphA4 receptors regulate formation of the principal inter-hemispheric tracts of the mammalian forebrain

Keywords: DKO، دو شکست ناپذیر; anterior commissure; axon guidance; Eph; MRIAC, anterior commissure; ACpa, anterior commissure pars anterior; ACpp, anterior commissure pars posterior; DKO, double knockout; DM, deformation magnitude; E, embryonic day; MRI, magnetic resonance imaging; PBS

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2009 سفارش ترجمه

Suppressor of Cytokine Signaling-1 Regulates Inflammatory Bowel Disease in Which Both IFNγ and IL-4 Are Involved

Keywords: DKO، دو شکست ناپذیر; COX, cyclooxygenase; DKO, double knockout; IFN, interferon; IκB, inhibitor of nuclear factor κB; IL, interleukin; iNOS, inducible nitric oxide synthase; JAK, Janus kinase; KO, knockout; LPS, lipopolysaccharides; MAb, monoclonal antibody; MEF, mouse embryo

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2006 سفارش ترجمه