Development of simulated intestinal fluids containing nutrients as transport media in the Caco-2 cell culture model: Assessment of cell viability, monolayer integrity and transport of a poorly aqueous soluble drug and a substrate of efflux mechanisms
Keywords: DMEM، Modified Eagle Medbill Dulbecco; A-B, apical to basolateral; B-A, basolateral to apical; DMEM, Dulbecco's modified eagle medium; FaSSIF, fasted state simulated intestinal fluid; FeSSIF, fed state simulated intestinal fluid; HBSS, Hanks’ balanced salt solution; L-15, Leibovitz's L-15 medi