Selective novel inverse agonists for human GPR43 augment GLP-1 secretion
Keywords: SCFA, short chain fatty acid; SAR, structure-activity relationship; GPCR, G-protein coupled receptor; hGPR43, human GPR43; mGPR43, mouse GPR43; NF-κB, nuclear factor kappa B; GLP-1, glucagon-like peptide-1; HTS, high throughput screening; DMSO, dimethyl s