In vitro selection of optimal RelB/p52 DNA-binding motifs
Keywords: اتصال DNA; Nuclear factor kappa B; DNA binding; Transcriptional factor; Signaling pathways
مقالات ISI اتصال DNA (ترجمه نشده)
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Cloning, purification and initial characterization of E. coli McrA, a putative 5-methylcytosine-specific nuclease
Keywords: اتصال DNA; McrA; Zn2+ finger; DNA methylation; C5-methylcytosine (m5C); DNA binding; CpG island affinity purification
Expression, purification, and characterization of multiple, multifunctional human glucocorticoid receptor proteins
Keywords: اتصال DNA; Nuclear receptor; Glucocorticoid receptor; DNA binding; Coactivator protein binding; Steroid binding
Synthesis, DNA binding and cleavage activities of the copper (II) complexes of estrogen-macrocyclic polyamine conjugates
Keywords: اتصال DNA; 1,4,7,10-Tetraazacyclododecane (cyclen); Copper (II) complexes; Estrogens; DNA binding; DNA cleavage
Design, synthesis, and biological evaluation of new mitonafide derivatives as potential antitumor drugs
Keywords: اتصال DNA; Cytotoxicity; DNA binding; Antitumor activity; Benzo[de]isoquinolines
Substituent control of DNA binding modes in a series of chalcogenoxanthylium photosensitizers as determined by isothermal titration calorimetry and topoisomerase I DNA unwinding assay
Keywords: اتصال DNA; Chalcogenoxanthylium dyes; DNA binding; Topoisomerase I unwinding assay; Isothermal titration calorimetry
Stimulation of the DNA unwinding activity of human DNA helicase II/Ku by phosphorylation
Keywords: اتصال DNA; DNA binding; DNA-dependent ATPase; DNA-PKcs; DNA metabolism; DNA unwinding enzyme; HDH II/Ku; Protein phosphorylation; Protein dephosphorylation
Synthesis and spectroscopic DNA binding studies of [Ru(phen)2(tbtc)]2+ and [Ru(2,9-dmp)2(tbtc)]2+
Keywords: اتصال DNA; Ruthenium(II) complex; Polypyridyl ligand; DNA binding; Photocleavage;
Synthesis, characterization, antioxidant activity and DNA-binding studies of two rare earth(III) complexes with naringenin-2-hydroxy benzoyl hydrazone ligand
Keywords: اتصال DNA; Naringenin-2-hydroxy benzoyl hydrazone; Rare earth(III) complex; DNA binding; Antioxidant activity
Oxoisoaporphine alkaloid derivatives: Synthesis, DNA binding affinity and cytotoxicity
Keywords: اتصال DNA; Oxoisoaporphine alkaloid derivatives; Synthesis; DNA binding; Cytotoxicity
Design, synthesis, and antitumor activity of new bis-aminomethylnaphthalenes
Keywords: اتصال DNA; Bis-aminomethylnaphthalenes; Synthesis; Antitumor activity; DNA binding
Experimental and DFT studies on DNA binding and photocleavage of two cationic porphyrins
Keywords: اتصال DNA; Cationic porphyrin; DNA binding; DNA photocleavage; DFT;
Synthesis, cytotoxic evaluation, and DNA binding of novel thiazolo[5,4-b]quinoline derivatives
Keywords: اتصال DNA; Thiazolo[5,4-b]quinoline derivatives; Antitumoral; Cytotoxic activity; Structure–activity relationship; DNA binding
Novel linear triaryl guanidines, N-substituted guanidines and potential prodrugs as antiprotozoal agents
Keywords: اتصال DNA; Antiprotozoan; Bis-guanidines; DNA binding; Triaryl guanidines
Synthesis, cellular uptake and structure-activity relationships for potent cytotoxic trichloridoiridium(III) polypyridyl complexes
Keywords: اتصال DNA; Iridium; Polypyridyl ligands; Cytotoxicity; Cellular uptake; DNA binding
Assembly Architecture and DNA Binding of the Bacteriophage P22 Terminase Small Subunit
Keywords: اتصال DNA; dsDNA, double-stranded DNA; EM, electron microscopyP22 bacteriophage; terminase structure; DNA binding; electron microscopy; Raman spectroscopy
Cobalt complexes of terpyridine ligands: Crystal structure and nuclease activity
Keywords: اتصال DNA; Cobalt complexes; Crystal structures; DNA binding; Oxidative cleavage
Analysis of the SRY gene in two sex-reversed XY sisters identifies two new novel point mutations in the high mobility group box domain
Keywords: اتصال DNA; SRY gene; primary amenorrhea; 46; XY sex reversal; two sisters; DNA binding;
DNA interaction of some polymer–copper(II) complexes containing 2,2′-bipyridyl ligand and their antimicrobial activities
Keywords: اتصال DNA; Polymer–copper(II) complex; 2,2′-Bipyridine; DNA binding; Electrostatic interactions
DNA binding and bending by dinuclear complexes comprising ruthenium polypyridyl centres linked by a bis(pyridylimine) ligand
Keywords: اتصال DNA; Bimetallo complexes; Ruthenium metal complexes; DNA binding; Linear dichroism; DNA bending;
Complex oligomeric structure of a truncated form of DdrA: A protein required for the extreme radiotolerance of Deinococcus
Keywords: اتصال DNA; Deinococcus; Radiotolerance; Electron microscopy; DdrA; DNA binding
Synthesis, micellar properties, DNA binding and antimicrobial studies of some surfactant-cobalt(III) complexes
Keywords: اتصال DNA; Surfactant-metal complexes; DNA binding; Antibacterial activity; Antifungal activity;
Targeting the gene in Friedreich ataxia
Keywords: اتصال DNA; Triplet repeat; Neurodegenerative; HDAC inhibitors; DNA binding; Frataxin;
Synthesis, DNA binding, and cytotoxicity of 1,4-bis(2-amino-ethylamino)anthraquinone–amino acid conjugates
Keywords: اتصال DNA; Anthraquinone; DNA binding; DNA affinity; Conjugate; Cytotoxicity
Mutations in the AF-2 region abolish ligand-induced intranuclear immobilization of the liver X receptor α
Keywords: اتصال DNA; Nuclear receptor; Liver X receptor; Activation function-2; DNA binding; Fluorescence recovery after photobleaching (FRAP); Trafficking; Permeabilization
Perylene side chains modulate G-quadruplex conformation in biologically relevant DNA sequences
Keywords: اتصال DNA; Perylene; G-quadruplex; DNA binding; Circular dichroism; Electrophoretic mobility shift assay
Synthesis, metal ion binding, and biological evaluation of new anticancer 2-(2′-hydroxyphenyl)benzoxazole analogs of UK-1
Keywords: اتصال DNA; Antibacterial; Metal ion binding; Cancer cell cytotoxicity; DNA binding
LEF-1 recognition of platinated GG sequences within double-stranded DNA. Influence of flanking bases
Keywords: اتصال DNA; Anticancer drugs; Cisplatin; DNA binding; HMGB proteins;
Synthesis, structural characteristics, DNA binding properties and cytotoxicity studies of a series of Ru(III) complexes
Keywords: اتصال DNA; Ru(III) complexes; Anticancer drug; DNA binding
Synthesis, structure, DNA binding and DNA cleavage activity of oxovanadium(IV) N-salicylidene-S-methyldithiocarbazate complexes of phenanthroline bases
Keywords: اتصال DNA; Oxovanadium(IV) complexes; DNA binding; DNA photocleavage; Crystal structure; Dithiocarbazate; Phenanthroline bases
Synthesis, GC selective DNA binding and topoisomerase II inhibition activities of ruthenium(II) polypyridyl complex containing 11-aminopteridino[6,7-f][1,10]phenanthrolin-13(12H)-one
Keywords: اتصال DNA; Ruthenium(II) complexes; DNA binding; Photocleavage; Topoisomerase inhibition
The ATPase Domain of the Large Terminase Protein, gp17, from Bacteriophage T4 Binds DNA: Implications to the DNA Packaging Mechanism
Keywords: اتصال DNA; dsDNA, double-stranded DNA; GF, gel filtration; gp, gene product(s); HTH, helix–turn–helix; ssDNA, single-stranded DNAvirus assembly; bacteriophage T4; DNA packaging; ATPase; DNA binding
Synthesis, structure, DNA binding and oxidative cleavage activity of ternary (l-leucine/isoleucine) copper(II) complexes of heterocyclic bases
Keywords: اتصال DNA; Copper; DNA binding; DNA cleavage; Crystal structure; l-Leucine; l-Isoleucine; Phenanthroline base
Synthesis, DNA binding and antitumor activities of some novel polymer–cobalt(III) complexes containing 1,10-phenanthroline ligand
Keywords: اتصال DNA; Polyethyleneimine; Cobalt(III) complexes; 1,10-Phenanthroline; DNA binding; Antitumor activity
Novel thiosemicarbazone derivatives as potential antitumor agents: Synthesis, physicochemical and structural properties, DNA interactions and antiproliferative activity
Keywords: اتصال DNA; Thiosemicarbazone; Antitumor evaluation; UV/vis spectroscopy; DNA binding
DNA binding and biological studies of some novel water-soluble polymer-copper(II)-phenanthroline complexes
Keywords: اتصال DNA; Polymer-copper(II) complexes; Antitumor activity; Antimicrobial activity; DNA binding; Polyethyleneimine;
Energetics of the binding of phototoxic and cytotoxic plant alkaloid sanguinarine to DNA: Isothermal titration calorimetric studies
Keywords: اتصال DNA; Sanguinarine; DNA binding; Isothermal titration calorimetry; Thermodynamic parameters
2,2′-Bipyridinebutyldithiocarbamatoplatinum(II) and palladium(II) complexes: Synthesis, characterization, cytotoxicity, and rich DNA-binding studies
Keywords: اتصال DNA; DNA binding; Cytotoxicity; Platinum complex; Palladium complex
DNA-binding and photocleavage properties of cationic porphyrin–anthraquinone hybrids with different lengths of links
Keywords: اتصال DNA; Cationic porphyrin–anthraquinone hybrids; DNA binding; Wavelength-dependent DNA photocleavage
Experimental and theoretical studies on the DNA-binding and spectral properties of water-soluble complex [Ru(MeIm)4(dpq)]2+
Keywords: اتصال DNA; Ru(II) complex; 1-Methylimidazole; DNA binding; Spectral property; DFT/TDDFTMeIm, 1-methylimidazole; bpy, 2,2′-bipyridine; dpq, dipyridoquinoxaline = pyrazino[2,3-f][1,10]phenanthroline; dppz, dipyrido-[3,2-a:2′3′-c]phenazine; hqdppz, 5,18-dihydroxynaphth
Expression and characterization of two STAT isoforms from Sf9 cells
Keywords: اتصال DNA; STAT; DNA binding; Baculovirus; Insect Sf9 cells
Studies on the reactivity of organometallic Ru–, Rh– and Os–pta complexes with DNA model compounds
Keywords: اتصال DNA; Anticancer drugs; DNA binding; Electrospray ionization mass spectrometry; pta; Arene–ruthenium complexes; Bioorganometallic chemistry
Cytotoxic half-sandwich rhodium(III) complexes: Polypyridyl ligand influence on their DNA binding properties and cellular uptake
Keywords: اتصال DNA; Bioorganometallic chemistry; Rhodium; Polypyridyl ligands; DNA binding; Cytotoxicity; Cellular uptake
Elucidation of the Structural Determinants Responsible for the Specific Formation of Heterodimeric Mxd1/Max b-HLH-LZ and Its Binding to E-Box Sequences
Keywords: اتصال DNA; HLH, helix–loop–helix; LZ, leucine zipper; CD, circular dichroism; dsDNA, double-stranded DNA; PDB, Protein Data Bank; PCR, polymerase chain reactiontranscription factors; b-HLH-LZ; heterodimerization; DNA binding; Myc/Max/Mxd network
Nbs1-dependent binding of Mre11 to adenovirus E4 mutant viral DNA is important for inhibiting DNA replication
Keywords: اتصال DNA; Adenovirus; E4 mutant; DNA replication; DNA binding; DNA damage response; MRN complex; Mdc1
DNA binding and photocleavage properties of a novel cationic porphyrin-anthraquinone hybrid
Keywords: اتصال DNA; Porphyrin-anthraquinone hybrid; DNA binding; DFT calculations; DNA photocleavage; Wavelength-depending;
Remodeling of the Human Papillomavirus Type 11 Replication Origin into Discrete Nucleoprotein Particles and Looped Structures by the E2 Protein
Keywords: اتصال DNA; HPV, human papillomavirus; ori, replication origin; E2BS, E2 binding site; URR, upstream regulatory region; E1BS, E1 binding site; EM, electron microscopy; BPV, bovine papillomavirusHPV; E2; EM; DNA binding; DNA looping
Biochemical Identification of Base and Phosphate Contacts between Fis and a High-Affinity DNA Binding Site
Keywords: اتصال DNA; Fis, factor for inversion stimulation; GEMSA, gel electrophoretic mobility shift assay; HTH, helix–turn–helix; NAP, nucleoid-associated protein; WT, wild typeFis; nucleoid-associated protein; DNA binding; ethylation interference; missing base contact
Cytotoxicity, mutagenicity, cellular uptake, DNA and glutathione interactions of lipophilic trans-platinum complexes tethered to 1-adamantylamine
Keywords: اتصال DNA; Cytotoxicity; Mutagenicity; DNA binding; Antitumor platinum; Adamantylamine ligand
Cooperative damage recognition by UvrA and UvrB: Identification of UvrA residues that mediate DNA binding
Keywords: اتصال DNA; DNA binding; Damage recognition; Nucleotide excision repair; UvrA; UvrBNER, nucleotide excision repair; ABC ATPase, ATP binding cassette ATPase; dsDNA, double-stranded DNA; EMSA, electrophoretic mobility shift assay; UV DNA, UV irradiated DNA; Bca, Bacill