دانلود مقالات ISI درباره Dnmt + ترجمه فارسی

DNA modifications in models of alcohol use disorders

Keywords: Alcohol; Epigenetics; DNA methylation; DNMT; DNA hydroxymethylation; TET; Alcohol use disorder; AUD; substance use disorder; SUD; fetal alcohol spectrum disorder; FASD; cytosine-phosphate-guanine; CpG; cytosine-phosphate-[non guanine base]; CpH; DNA methy

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Design, synthesis and anticancer potential of NSC-319745 hydroxamic acid derivatives as DNMT and HDAC inhibitors

Keywords: Epigenetic targets; Multi-target; Drug design; Antitumor bioactivity; DNMT; HDAC; ZQXQMHUCXRXRGT-FHWVORQXSA-N;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

DNA methyltransferase inhibitors in cancer: From pharmacology to translational studies

Keywords: DNMT; DNA methyltransferase; 5azadC; 5-aza-2′-deoxycytidine; 5azaC; 5-azacytidine; SAM; S-adenosyl-l-methionine; SAH; S-adenosyl-l-homocysteine; DNMTi; DNMT inhibitors; HDACi; histone deacetylase inhibitors; CpGs; 5′-CpG-3′ dinucleotides; CGis; CpG

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Dynamics and Context-Dependent Roles of DNA Methylation

Keywords: mES; murine embryonic stem; DNMT; DNA methyltransferase; DNMT3A; DNA methyltransferase 3A; DNMT3B; DNA methyltransferase 3B; DNMT1; DNA methyltransferase 1; H3K36me3; histone H3 lysine-36 trimethylation; ES; embryonic stem; UHRF1; ubiquitin-like with PHD

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2017 سفارش ترجمه

Metabolic programming of the epigenome: host and gut microbial metabolite interactions with host chromatin

Keywords: α-KG; alpha-ketoglutarate; acetyl-CoA; acetyl coenzyme A; BBB; blood brain barrier; bSCFA; branched short chain fatty acid; CoA; coenzyme A; ConvD; conventionalized; ConvR; conventionally raised; CRC; colorectal cancer; DNMT; DNA methyltransferase; GF; g

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2017 سفارش ترجمه

Inhibition of DNA Methylation in the COL1A2 Promoter by Anacardic Acid Prevents UV-Induced Decrease of Type I Procollagen Expression

Keywords: 5-AZA-dc; 5-AZA-2′-deoxycytidine; AA; anacardic acid; bp; base pair; ChIP; chromatin immunoprecipitation; CPG; 5′-cytosine-phosphate-guanine-3′; DNMT; DNA methyltransferase; HAT; histone acetyltransferase; HDF; human dermal fibroblast; MMP; matrix m

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2017 سفارش ترجمه

Radiation-induced DNA-protein cross-links: Mechanisms and biological significance

Keywords: C-ion; carbon-ion; DNMT; DNA methyltransferase; DPC; DNA-protein cross-link; DSB; DNA double-strand break; FITC; fluorescein isothiocyanate; GC-MS; gas chromatography-mass spectrometry; HR; homologous recombination; LET; linear energy transfer; MAR; mat

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2017 سفارش ترجمه

Atrazine exposure decreases the activity of DNMTs, global DNA methylation levels, and dnmt expression

Keywords: Atrazine; dnmt; Epigenetics; Methylation; Zebrafish;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2017 سفارش ترجمه

TGFβ-incurred epigenetic aberrations of miRNA and DNA methyltransferase suppress Klotho and potentiate renal fibrosis

Keywords: CKD; chronic kidney disease; UUO; unilateral ureteral occlusion; TGFβ; transforming growth factor-beta; DNMT; DNA methyltransferase; MTD; myofibroblast trans-differentiation; MSP; methylation-specific PCR; BSP; bisulfite-sequencing PCR; Renal fibrosis; K

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2017 سفارش ترجمه

Hyper-methylation of the upstream CpG island shore is a likely mechanism of GPER1 silencing in breast cancer cells

Keywords: GPER1; G-protein coupled Estrogen Receptor; COBRA; Combined Bisulfite and Restriction Analysis; RT-PCR; Reverse Transcriptase Polymerase Chain Reaction; TBE-PAGE; Tris Borate EDTA Polyacrylamide Gel Electrophoresis; cAMP; cyclic adenosine monophosphate; P

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2017 سفارش ترجمه

DNA methylation in lung tissues of mouse offspring exposed in utero to polycyclic aromatic hydrocarbons

Keywords: Polycyclic aromatic hydrocarbon; Lung cancer; DNA methylation; Transplacental; Epigenetics; Methylated DNA immunoprecipitation; AdjBaP; lung tissue adjacent to a tumor from BaP-exposed offspring; AdjDBC; lung tissue adjacent to a tumor from BaP-exposed of

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2017 سفارش ترجمه

In utero exposure to carcinogens: Epigenetics, developmental disruption and consequences in later life

Keywords: 5-mc; 5-methylcytosine; AhR; aryl hydrocarbon receptor; AKT; protein kinase B; BPA; bisphenol A; CNS; central nervous system; CS; cigarette smoke; DBP; dibenzo(α1) pyrene; DES; diethylstilboestrol; DNMT; N-methyltransferase; E2; 17-β-oestradiol; ED; end

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

DNA methylation in Huntington's disease: Implications for transgenerational effects

Keywords: HD; Huntington's disease; Htt; huntingtin; DNMT; DNA methyltransferase; HDAC; histone deacetylase; DNA methylation; Epigenetic; Transgenerational; Neurodegenerative;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

DNMT3a expression pattern and its prognostic value in lung adenocarcinoma

Keywords: DNMT; DNA methyl transferase; IHC; immunohistochemistry; AAH; adenomatous atypical hyperplasia; AIS; adenocarcinoma in situ; MIA; minimally invasive adenocarcinoma; DNMT3a; Expression pattern; Lung adenocarcinoma; Prognosis;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Combined effects of DNA methyltransferase 1 and 3A polymorphisms and urinary total arsenic levels on the risk for clear cell renal cell carcinoma

Keywords: Arsenic; DNMT; Renal cell carcinoma;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Biflorin induces cytotoxicity by DNA interaction in genetically different human melanoma cell lines

Keywords: AKT; murine thymoma viral oncogene homolog 1; BRAF; v-raf murine sarcoma viral oncogene homolog B; DNMT; DNA methyltransferase; ERK; extracellular regulating kinase; MAPK; mitogenic activated protein kinase; MBP; methyl-CpG binding proteins; MELK; materna

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Nephrotoxicity of epigenetic inhibitors used for the treatment of cancer

Keywords: Epigenetic inhibitors; Prostate cancer; Kidney cells; Nephrotoxicity; 5-Aza; 5-aza-2ʹ-deoxycytidine; CBZ; carbamazapine; CDK; cyclin-dependent kinase; CDKN1a; cyclin-dependent kinase inhibitor 1a; CFZ; carfilzomib; ChIP; chromatin immunoprecipitation; DM

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Regulation of the ErbB network by the MIG6 feedback loop in physiology, tumor suppression and responses to oncogene-targeted therapeutics

Keywords: RTK; receptor tyrosine kinase; EGF; epidermal growh factor; EGFR; epidermal growth factor receptor; LRIG1; leucin-rich repeats and immunoglobulin-like domains1; MIG; 6mitogen inducible gene 6; RALT; receptor associated late transducer; ERRFI1; ErbB recept

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Research updateOxidative stress, autophagy, epigenetic changes and regulation by miRNAs as potential therapeutic targets in osteoarthritis

Keywords: ADAMTS; a disintegrin and metalloproteinase with thrombospondin motifs; AGEs; advanced glycation end products; ATG; autophagy-related gene; Col2; type II collagen; DNMT; DNA methyltransferase; ERK; extracellular signal-regulated kinase; HDAC; histone deac

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Active DNA demethylation by DNA repair: Facts and uncertainties

Keywords: 5mC; 5-methylcytosine; 5hmC; 5-hydroxymethylcytosine; 5hmU; 5-hydroxymethyluracil; 5fC; 5-formylcytosine; 5caC; 5-carboxycytosine; AID; activation-induced deaminase; APE1; apurinic/apyrimidinic endonuclease 1; APOBEC; apolipoprotein B mRNA editing enzyme,

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

5-aza-2′-deoxycytidine impairs mouse spermatogenesis at multiple stages through different usage of DNA methyltransferases

Keywords: Mouse spermatogenesis; DNA methylation; HELMET; DNMT; 5-aza-2′-deoxycytidine; Apoptosis

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Research ArticleHepatic stellate cell transdifferentiation involves genome-wide remodeling of the DNA methylation landscape

Keywords: 5-hmC; 5-hydroxymethylcytosine; 5-mC; 5-methylcytosine; aHSC; activated hepatic stellate cells; ALD; alcoholic liver disease; DNMT; DNA methyltransferase; HSC; hepatic stellate cells; MeCP2; methyl-CpG binding protein 2; NHL; normal human liver; PSC; prim

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Mechanisms of allergy and clinical immunologyIL-6 promotes an increase in human mast cell numbers and reactivity through suppression of suppressor of cytokine signaling 3

Keywords: Mast cells; signal transducer and activator of transcription 3; suppressor of cytokine signaling 3; stem cell factor; IL-6; mastocytosis; ADAM; A disintegrin and metalloproteinase; DNMT; DNA methyltransferase; ERK; Extracellular signal-regulated kinase; g

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

Hepatitis B virus basal core promoter mutations show lower replication fitness associated with cccDNA acetylation status

Keywords: BCP; basal core promoter; CHB; chronic HBV; cccDNA; covalently closed circular DNA; DNMT; DNA methyltransferases; DS DNA; double stranded DNA; HATs; histone acetyltransferases; HDAC1; class 1 histone deacetylase; OC DNA; open circular DNA; ORFs; open read

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2016 سفارش ترجمه

HIC1 epigenetically represses CIITA transcription in B lymphocytes

Keywords: Transcriptional regulation; Epigenetics; HIC1; CIITA; DNMT;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2016 سفارش ترجمه

Dynamic epigenetic mechanisms regulate age-dependent SOX9 expression in mouse articular cartilage

Keywords: ACs; articular chondrocytes; H3K4me2; histone 3 lysine 4 dimethylation; OA; osteoarthritis; WT; wild-type; IHC; immunohistochemistry; HE; haematoxylin and eosin; qPCR; quantitative real-time RT-PCR; P1; first passage of cultured cells; MeDIP; methylated D

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2016 سفارش ترجمه

Epigenetic modifications of triterpenoid ursolic acid in activating Nrf2 and blocking cellular transformation of mouse epidermal cells

Keywords: UA; Nrf2; JB6 P+; DNMT; HDAC; Skin cancer;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2016 سفارش ترجمه

Epigenetic response to environmental stress: Assembly of BRG1-G9a/GLP-DNMT3 repressive chromatin complex on Myh6 promoter in pathologically stressed hearts

Keywords: Histone methylation; DNA methylation; Chromatin remodeling; Gene silencing; Myosin heavy chain; G9a; Dnmt; Brg1; H3K9me2; Cardiac hypertrophy; Cardiomyopathy; Heart failure;

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2016 سفارش ترجمه

Epigenetic reactivation of RASSF1A by phenethyl isothiocyanate (PEITC) and promotion of apoptosis in LNCaP cells

Keywords: PEITC; phenethyl isothiocyanate; RASSF1A; RAS superfamily protein isoform 1A; DNMT; DNA methyl transferases; HDAC; histone deacetylases; MSP; methylation specific PCR; BGS; bisulfite genomic sequencing; PCa; prostate cancer; RASSF1A; Epigenetics; Demethyl

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2016 سفارش ترجمه

Global changes in DNA methylation in Alzheimer's disease peripheral blood mononuclear cells

Keywords: Alzheimer's disease; APOE; DNA methylation; DNMT; Epigenetics; PBMC; Peripheral markers; Pyrosequencing;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Effect of DNMT inhibitor on bovine parthenogenetic embryo development

Keywords: DNMT; RG108; DNA methylation; Bovine parthenogenetic preimplantation embryos; DNMT; DNA methyltransferase; DNMTi; DNA methyltransferase inhibitor; P2; parthenogenetic 2-cell embryos; P4; parthenogenetic 4-cell embryos; P8; parthenogenetic 8-cell embryos;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

DNMT1 and EZH2 mediated methylation silences the microRNA-200b/a/429 gene and promotes tumor progression

Keywords: Histone modifications; DNA methylation; miR-200; DNMT; EZH2

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

DNA methylation regulates neurophysiological spatial representation in memory formation

Keywords: Memory; Spatial memory; Place cells; Epigenetic; Neuroepigenetics; DNA methylation; Bdnf; DNMT; Hippocampus

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

SALL4: An emerging cancer biomarker and target

Keywords: ESCs; embryonic stem cells; AML; acute myeloid leukemia; CSCs; cancer stem cells; iPS; induced pluripotent stem cell; HSCs/HPCs; hematopoietic stem/progenitor cells; MDS; myelodysplastic syndrome; LSCs; leukemic stem cells; CML; chronic myeloid leukemia;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Hypermethylation in gastric cancer

Keywords: 5-hmC; 5-hydroxymethylcytosine; 5-mC; 5-methylcytosine; ADAM23; ADAM metallopeptidase domain 23; APC; adenomatosis polyposis coli; ATP; adenosine-triphosphate; BCL6B; B-Cell CLL/Lymphoma 6, Member B; BGS; bisulfite genomic sequencing; BMP-2; bone morphoge

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Research reportReduced serine racemase expression in aging rat cerebellum is associated with oxidative DNA stress and hypermethylation in the promoter

Keywords: SR; serine racemase; DAAOx; D-amino acid oxidase; DNMT; DNA methyltransferase; HDAC1; histone deacetylase 1; 5-mC; 5-methylcytosine; 5-hmC; 5-hydroxymethylcytosine; PCR; polymerase chain reaction; qRT-PCR; quantitative real-time PCR; BSP; bisulfite sequen

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Epimutagenesis: A prospective mechanism to remediate arsenic-induced toxicity

Keywords: WHO; World Health Organization; MPL; maximum permissible limit; NPDS; National Poison Data System; BCC; basal cell carcinoma; SCC; squamous cell carcinoma; BD; Bowen's disease; iAs; inorganic arsenic; SAM; S-adenosyl methionine; ROS; reactive oxygen speci

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Developmental exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin alters DNA methyltransferase (dnmt) expression in zebrafish (Danio rerio)

Keywords: TCDD; Zebrafish development; dnmt; Aryl hydrocarbon receptor; Dioxin; DNA methylation;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Blockage of TGFβ-SMAD2 by demethylation-activated miR-148a is involved in caffeic acid-induced inhibition of cancer stem cell-like properties in vitro and in vivo

Keywords: CaA; 3,4-dihydroxycinnamic acid; CSCs; cancer stem cells; DNMT; DNA methyltransferases; HCC; hepatocellular carcinoma; miR-148a; microRNA-148a; qMSP; quantitative methylation-specific polymerase chain reaction; SAM; S-adenosylmethionine; TGFβ; transformi

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Psammaplin A induces Sirtuin 1-dependent autophagic cell death in doxorubicin-resistant MCF-7/adr human breast cancer cells and xenografts

Keywords: AMPK; AMP-activated protein kinase; Atg; autophagy-related gene; BAX; Bcl-2-associated X protein; DNMT; DNA methyltransferase; Dox; doxorubicin; DRAM; damage-regulated autophagy modulator; HDAC; histone deacetylase; LC3; microtubule-associated protein 1 l

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Hydroxymethylation and its potential implication in DNA repair system: A review and future perspectives

Keywords: C; Cytosine; DNMT; DNA methyl transferase; BER; Base Excision Repair; NER; Nucleotide Excision Repair; TET; Ten Eleven Translocation protein; 5mC; 5methylcytosine; 5hmC; 5-hydroxymethylcytosine; 5fC; 5-formylcytosine; 5caC; 5-carboxylcytosine; ESC; Embryo

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Dynamic expression of DNA methyltransferases (DNMTs) in oocytes and early embryos

Keywords: DNMT; DNA methylation; Oocyte; Early embryo; Gene expression

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Epigenetic control of EMT/MET dynamics: HNF4α impacts DNMT3s through miRs-29

Keywords: ChIP; chromatin immunoprecipitation; DNMT; DNA methyltransferase; EMT; epithelial to mesenchymal transition; MET; mesenchymal to epithelial transition; TGFβ; transforming growth factor β; HNF4α; hepatocyte nuclear factor 4 alpha; qPCR; real-time polyme

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Germline-derived DNA methylation and early embryo epigenetic reprogramming: The selected survival of imprints

Keywords: 5mC; 5-methylcytosine; ES cells; embryonic stem cells; SAM; S-adenosyl-methionine; Dnmt; DNA methyltransferase; Uhrf1; Ubiquitin-like, containing PHD and RING finger domains 1; H3K; Histone H3 lysine; Cfp1; CXXC finger protein 1; Ezh2; enhancer of zeste h

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Novel aberrant genetic and epigenetic events in Friedreich׳s ataxia

Keywords: FRDA; Friedreich׳s ataxia; FXN; frataxin; ISC; iron-sulphur cluster; hPDL; human periodontal ligament; CASP3; active caspase-3; DNMT; DNA methyltransferase; CpG; cytosine phosphate group guanine; TSS; transcription start site; UP; upstream GAA repetiti

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Using patient-specific induced pluripotent stem cells to interrogate the pathogenicity of a novel retinal pigment epithelium-specific 65 kDa cryptic splice site mutation and confirm eligibility for enrollment into a clinical gene augmentation trial

Keywords: Best1; Bestrophin1; bFGF; basic fibroblast growth factor; DMEM; Dulbecco's Modified Eagle Medium; DNMT; DNA methyltransferases; ERG; Electroretinography; KLF4; Kruppel-like factor 4; LB; Lysogeny broth; LCA; Leber congenital amaurosis; MEM; minimum essent

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Effects of oral exposure to bisphenol A on gene expression and global genomic DNA methylation in the prostate, female mammary gland, and uterus of NCTR Sprague-Dawley rats

Keywords: BPA; bisphenol A; bw; body weight; C3; complement component 3-coding gene; CMC; carboxymethylcellulose; Ct; threshold cycle; Dnmt; DNA methyltransferase-coding gene; EE2; ethinyl estradiol; ER; estrogen receptor; Esr; estrogen receptor-coding gene; FDR; f

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Epigenetics of idiopathic pulmonary fibrosis

Keywords: α-SMA; α-smooth muscle actin; DNMT; DNA methyltransferase; ECM; extracellular matrix; EMT; epithelial-mesenchymal transition; HDAC; histone deacetylase; IPF; idiopathic pulmonary fibrosis; MeCP2; methyl CpG binding protein 2; miRNA; micro-RNA; MMP; matr

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Genistein increases estrogen receptor beta expression in prostate cancer via reducing its promoter methylation

Keywords: 5-Aza-dC; 5-Aza-2′-deoxycytidine; AR; androgen receptor; DMSO; dimethyl sulfoxide; DNMT; DNA methyltransferase; ER-β; estrogen receptor beta; FOXO-1; forkhead box O-1; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; MBD; methyl binding domain; MSP; me

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

A piece of the pi(e): The diverse roles of animal piRNAs and their PIWI partners

Keywords: AGO; Argonaute clade protein; Ago3; Argonaute 3; Armi; Armitage; Arx; Asterix; Aub; Aubergine; CBC; cap-binding complex; Dnmt; DNA methyltransferase; dsRNA; double-stranded RNA; ESC; embryonic stem cell; esiRNA; endogenous small interfering RNA; GSC; germ

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه