Keywords: مبادله دامنه; Endolysin; Enzybiotics; Engineering; Mutagenesis; Truncation; Domain swapping; Fusions; clinical trials;
مقالات ISI مبادله دامنه (ترجمه نشده)
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Keywords: مبادله دامنه; Amylosucrase; Deinococcus geothermalis; Neisseria polysaccharea; Domain swapping; Chimeric enzyme
Keywords: مبادله دامنه; Perilla; Labiatae; Geraniol synthase; Linalool synthase; Domain swapping; Site-directed mutagenesis; Chimeric enzymes; Regiospecific hydroxylation; Essential oil;
Domain swapping dissection in Thermotoga maritima arginine binding protein: How structural flexibility may compensate destabilization
Keywords: مبادله دامنه; TmArgBP; arginine binding protein isolated from Thermotoga maritima; TmArgBP20-233; truncated form of TmArgBP; arg-TmArgBP20-233; arginine-bound form of TmArgBP20-233; lf-TmArgBP20-233; ligand-free form of TmArgBP20-233; TmArgBP_C-ter232-246; peptide corr
Domain swapping between FabGs deciphers the structural determinant for in-solution oligomerization and substrate binding
Keywords: مبادله دامنه; Fatty acid biosynthesis; Domain swapping; In-solution oligomerization; Fluorescence spectroscopy; in vivo complementation; Acyl-CoA binding;
Engineered domain swapping indicates context dependent functional role of RNA G-quadruplexes
Keywords: مبادله دامنه; RNA engineering; G-quadruplex; Domain swapping; Nucleic acid structure-function relationship;
An atypical segment swap in the DN and DC domains of the Acr_tran family resistance-nodulation-cell division pump
Keywords: مبادله دامنه; Domain swapping; Fold change; Metamorphic proteins; Membrane proteins; Domain duplication; RND pump;
The integrin αL leg region controls the Mg/EGTA mediated activation of LFA-1
Keywords: مبادله دامنه; Divalent cation; Integrin activation; Domain swapping; Cell adhesion; EGTA; Ethylene glycol tetra-acetic acid; LFA-1; Leukocyte function associated antigen-1 (αLβ2); Mac-1; Macrophage antigen-1 (αMβ2); ICAM; Intercellular adhesion molecule; BSA; Bovin
The βγ-crystallins: Native state stability and pathways to aggregation
Keywords: مبادله دامنه; Crystallin; Stability; Aggregation; Folding intermediate; Amyloid; Domain swapping
OmpA can form folded and unfolded oligomers
Keywords: مبادله دامنه; cmc; critical micelle concentration; FL-OmpA; full-length OmpA; OmpA; outer membrane protein A; POPC; 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine; POPG; 1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1â²-rac-glycerol) (sodium salt); SDS-PAGE; sodium dod
The sequence variation responsible for the functional difference between the CONSTANS protein, and the CONSTANS-like (COL) 1 and COL2 proteins, resides mostly in the region encoded by their first exons
Keywords: مبادله دامنه; CO; COL1; COL2; Flowering time; Domain swapping; Evolution;
Investigating Monoclonal Antibody Aggregation Using a Combination of H/DX-MS and Other Biophysical Measurements
Keywords: مبادله دامنه; Antibody dimerization; Protein aggregation; Chromatography; Electrophoresis; Hydrogen-deuterium exchange mass spectrometry (H/DX-MS); Calorimetry (DSC); Protein structure; Small-angle X-ray solution scattering (SAXS); Domain swapping;
Verification of the interdomain contact site in the inactive monomer, and the domain-swapped fold in the active dimer of Hsp33 in solution
Keywords: مبادله دامنه; Hsp33; Molecular chaperone; Interdomain contact site; Domain swapping; Chemical shift perturbation; Fluorescence quenching
p38α MAP Kinase Dimers with Swapped Activation Segments and a Novel Catalytic Loop Conformation
Keywords: مبادله دامنه; MAPK, mitogen-activated protein kinase; MKK, MAPK kinase; SLK, Ste20-like kinase; ESRF, European Synchrotron Radiation Facility; PDB, Protein Data Bankp38α; homodimerization; noncanonical; autoactivation; domain swapping
Insights into Strand Exchange in BTB Domain Dimers from the Crystal Structures of FAZF and Miz1
Keywords: مبادله دامنه; FAZF, Fanconi anemia zinc finger; PLZF, promyelocytic leukemia zinc finger; PDB, Protein Data Bank; PEG, polyethylene glycolBTB domains; protein–protein associations; domain swapping; molecular evolution
Does domain swapping improve the stability of RNase A?
Keywords: مبادله دامنه; Ribonuclease; RNase A; Domain swapping; Biomaterials
Substrate specificities of family 1 UGTs gained by domain swapping
Keywords: مبادله دامنه; Domain swapping; Glycosylation; Glycosyltransferase; Biocatalysis; Resveratrol; Etoposide; Curcumin; ADME improvement; Combinatorial biochemistry;
Engineering and kinetic characterisation of two glucosyltransferases from Arabidopsis thaliana
Keywords: مبادله دامنه; Protein engineering; Glucosyltransferases; Domain swapping; Glycosylation; Enzyme kineticsGT, glucosyltransferase; UDP-Glc, uridine-diphospho-β-d-glucose; ORF, open reading frame; UDP-2FGlc, UDP-2-deoxy-2-fluoro glucose
Crystal Structure of the Ig1 Domain of the Neural Cell Adhesion Molecule NCAM2 Displays Domain Swapping
Keywords: مبادله دامنه; crystal structure; differential scanning calorimetry; domain swapping; gel filtration; neural cell adhesion molecule 2CAM, cell adhesion molecule; NCAM, neural cell adhesion molecule
Mechanism and Energy Landscape of Domain Swapping in the B1 Domain of Protein G
Keywords: مبادله دامنه; GB1, immunoglobulin G binding protein from group G of Streptococcus; wt, wild type; NCSD, non-contiguous structural domain; RC, reaction coordinate; MG, molten globule; MRR, multiple replica repulsionprotein interactions; domain swapping; encounter comple
Sequence and Structural Determinants of Strand Swapping in Cadherin Domains: Do All Cadherins Bind Through the Same Adhesive Interface?
Keywords: مبادله دامنه; EC, extracellular cadherin; HMM, hidden Markov modelcadherins; adhesion; domain swapping; strand swapping; cell surface receptors
A single amino acid in the PSPG-box plays an important role in the catalytic function of CaUGT2 (Curcumin glucosyltransferase), a Group D Family 1 glucosyltransferase from Catharanthus roseus
Keywords: مبادله دامنه; Glucosyltransferase; Curcumin; PSPG-box; Catalytic function; Domain swapping; Site-directed mutagenesis
The lid is a structural and functional determinant of lipase activity and selectivity
Keywords: مبادله دامنه; Candida rugosa lipase isoform 1; Bacillus subtilis lipase A; Pseudomonas fragi lipase; Specificity; Temperature stability; Enantioselectivity; Site-directed mutagenesis; Domain swapping
The membrane anchors of the heme chaperone CcmE and the periplasmic thioredoxin CcmG are functionally important
Keywords: مبادله دامنه; Cytochrome c maturation; Domain swapping; Heme chaperone; Membrane anchor; Periplasmic proteins; Thioredoxin
The three-dimensional structure of an eukaryotic glutamine synthetase: Functional implications of its oligomeric structure
Keywords: مبادله دامنه; Glutamine synthetase; Electron microscopy; Oligomerization; Domain swapping
On the thermal stability of the two dimeric forms of ribonuclease A
Keywords: مبادله دامنه; Domain swapping; Circular dichroism; Differential scanning calorimetry; Structure-stability relationship; Protein aggregation; Open and closed interface;
Odorant binding initially occurring at the central pocket in bovine odorant-binding protein
Keywords: مبادله دامنه; Odorant-binding protein; Dimeric structure; Domain swapping; Central pocket; Internal cavity; Tryptophan fluorescence;
Synthesis and analysis of chimeric maize glutathione transferases
Keywords: مبادله دامنه; Dimerisation; GSTs; Herbicide detoxification; Protein engineering; Domain swapping; Phi class GST; Tau class GST; Zea mays;