Keywords: 6-OHDA; 6-hydroxydopamine; Aβ; amyloid-β; AD; Alzheimer disease; ALS; amyotrophic lateral sclerosis; APOE4; apolipoprotein E4; APP; amyloid precursor protein; ASCL1; achaete-scute family basic helix-loop-helix transcription factor 1; ATP; adenosine trip
مقالات ISI (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: α-KG; alpha-ketoglutarate; 2-HG; 2-hydroxyglutarate; 5hmC; 5-hydroxymethylcytosine; 5mC; 5-methylcytosine; AML; acute myeloid leukemia; ASXL1; additional sex combs-like 1; AZA; azacytidine; CMML; chronic myelomonocytic leukemia; DAC; decitabine; DNMT3A;
Keywords: Induced pluripotent stem cells; Regenerative medicine; Sarcopenia; In vivo reprogramming; DOT1L
Discovery of potent DOT1L inhibitors by AlphaLISA based High Throughput Screening assay
Keywords: DOT1L; MLL-rearranged leukemia; AlphaLISA; HTS; Novel inhibitors;
Double sword role of EZH2 in leukemia
Keywords: EZH1,2; enhancer of Zeste 1 and 2; SUZ12; suppressor of zeste 12 homolog; EED; embryonic ectoderm development; AEBP2; adipocyte enhancer-binding protein 2; RBAP46/48; retinoblastoma binding proteins 46 and 48; PRC; polycomb-repressive complex; PcG; Polyco
JNK1 as a signaling node in VDR-BRAF induction of cell death in AML
Keywords: AP-1; Activator protein 1, c-Jun and dimerization partners; AKT; Serine/threonine protein kinase B (PKB); AML; Acute myeloid leukemia; AraC; Cytarabine/Arabinocytosine; ASK1; Apoptosis signal regulating kinase 1; BCL2; B-cell lymphoma 2; BIM; Bcl-2-like p
Association of H3K79 monomethylation (an epigenetic signature) with arsenic-induced skin lesions
Keywords: Arsenic-induced skin lesion; Epigenetic signature; DNA damage; H3K79me1; DOT1L;
Update on rational targeted therapy in AML
Keywords: High-risk AML; IDH; BET; HDAC inhibitors; LSD1; DOT1L; Flavopiridol; Palbociclib; Volasertib; Wee1; Idasanutlin; Aurora kinase; Rigosertib; Hedgehog; BH3-mimetic; Venetoclax; Pevonedistat; Tosedostat
ReviewResetting the epigenome for heart regeneration.
Keywords: BMP; bone morphogenetic protein; Bvht; braveheart; CBP; CREB-binding protein; Cdkn; cyclin dependent kinase inhibitor; DOT1L; disruptor of telomeric silencing-1; DNMTs; DNA methyltransferases; eRNAs; , enhancer RNAs; ESCs; embryonic stem cells; FGF; fibro
Leukemogenic MLL-ENL Fusions Induce Alternative Chromatin States to Drive a Functionally Dichotomous Group of Target Genes
Keywords: leukemia; chromatin; MLL-ENL; P-TEFb; DOT1L; inhibitors
Genética de la artrosis
Keywords: ADNmt; ADN mitocondrial (mitochondrial DNA); ALDH1A2; retinaldehÃdo deshidrogenasa 2 (retinaldehyde dehydrogenase 2); ASTN2; astrotactina 2 (astrotactin-2); BMI; Ãndice de masa corporal (body mass index); BMP; proteÃna morfogenética ósea (bone minera
Exploring drug delivery for the DOT1L inhibitor pinometostat (EPZ-5676): Subcutaneous administration as an alternative to continuous IV infusion, in the pursuit of an epigenetic target
Keywords: Pinometostat (EPZ-5676); EPZ-5676; Pinometostat; MLL-r; DOT1L; Subcutaneous; Continuous IV;
MLL-Rearranged Acute Lymphoblastic Leukemias Activate BCL-2 through H3K79 Methylation and Are Sensitive to the BCL-2-Specific Antagonist ABT-199
Keywords: apoptosis pathways; leukemias; bcl-2 family members; MLL/AF4; DOT1L; H3K79 methylation
Opportunities for translation: Targeting DNA repair pathways in pancreatic cancer
Keywords: ATR; ATM-Rad3-related; BER; base excision repair; Chk1; checkpoint kinase 1; DDR; DNA damage response and repair; DNA-PKcs; DNA-PK catalytic subunit; DOT1L; DOT1-like; DSB; double strand break; FOLFIRINOX; folinic acid, 5-FU, irinotecan, oxaliplatin; 5-FU
Bromo-deaza-SAH: A potent and selective DOT1L inhibitor
Keywords: Protein methyltransferase; DOT1L; Leukemia; Inhibitor; Crystallography;