Keywords: DPP-4، dipeptidyl peptidase-4; DPP-4, dipeptidyl peptidase-4; GLP-1, glucagon-like peptide-1; RT-PCR, real-time polymerase chain reaction; O2 consumption, oxygen consumption; UCP-3, uncoupling protein-3Dipeptidyl peptidase-4; Obesity; Energy expenditure; Adipocyte hypertrophy; Hepatic
مقالات ISI DPP-4، dipeptidyl peptidase-4 (ترجمه نشده)
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A post hoc analysis of saxagliptin efficacy and safety in patients with type 2 diabetes stratified by UKPDS 10-year cardiovascular risk score
Keywords: DPP-4، dipeptidyl peptidase-4; Coronary heart disease; Saxagliptin; Stroke; Type 2 diabetes; UKPDS risk scoreADA, American Diabetes Association; AEs, adverse events; CHD, coronary heart disease; CV, cardiovascular; CVD, cardiovascular disease; DPP-4, dipeptidyl peptidase-4; EASD, Europ
Dipeptidyl peptidase-4 inhibitor, linagliptin, ameliorates endothelial dysfunction and atherogenesis in normoglycemic apolipoprotein-E deficient mice
Keywords: DPP-4، dipeptidyl peptidase-4; DPP-4, dipeptidyl peptidase-4; Lina, linagliptin; ApoE−/−, apolipoprotein-E deficient; GLP-1, glucagon-like peptide-1; Ex-4, exendin-4; PA, palmitic acid; WTD, western-type diet; CMC, carboxymethyl cellulose; 8-OHdG, 8-hydroxy-2′-deoxyguanosine; MCP-1, mo
Albiglutide: Is a better hope against diabetes mellitus?
Keywords: DPP-4، dipeptidyl peptidase-4; T2DM, type 2 Diabetes mellitus; GLP-1R, glucagon like peptide-1 receptor; GIP, gastric inhibitory peptide; GIT, gastrointestinal tract; DPP-4, dipeptidyl peptidase-4; GPCR, G-protein coupled receptor; cAMP, cyclic adenosine monophosphate; AC, adenylyl cyc
The DPP-4 inhibitor linagliptin and the GLP-1 receptor agonist exendin-4 improve endothelium-dependent relaxation of rat mesenteric arteries in the presence of high glucose
Keywords: DPP-4، dipeptidyl peptidase-4; DPP-4, dipeptidyl peptidase-4; DPI, diphenyliodonium; eNOS, endothelial nitric oxide synthase; EDHF, endothelium-dependent hyperpolarization Factor; GIP, glucose-dependent insulinotropic polypeptide; GLP-1R, glucagon-like peptide-1 receptor; IKCa, interme
Ezetimibe Stimulates Intestinal Glucagon-Like Peptide 1 Secretion Via the MEK/ERK Pathway Rather Than Dipeptidyl Peptidase 4 Inhibition
Keywords: DPP-4، dipeptidyl peptidase-4; DPP-4, dipeptidyl peptidase-4; ERK, extracellular signal-regulated kinase; GLP-1, glucagon like peptide-1; MEK, mitogen-activated protein/extracellular signal-regulated kinase (MAPK/ERK) kinase; NPC1L1, Niemann-Pick C1-Like 1; PC3, prohormone convertase 3
Gemigliptin, a dipeptidyl peptidase-4 inhibitor, inhibits retinal pericyte injury in db/db mice and retinal neovascularization in mice with ischemic retinopathy
Keywords: DPP-4، dipeptidyl peptidase-4; ROS, reactive oxygen species; DPP-4, dipeptidyl peptidase-4; GLP-1, glucagon-like peptide-1; VEGF, vascular endothelial growth factor; ICAM-1, intercellular adhesion molecule-1; PAI-1, plasminogen activator inhibitor-1; PEDF, pigment epithelium-derived fa
Antidiabetic potential of a novel dual-target activator of glucokinase and peroxisome proliferator activated receptor-γ
Keywords: DPP-4، dipeptidyl peptidase-4; GK, glucokinase; PPARγ, peroxisome proliferator activated receptor-γ; GLP-1, glucogan-like peptide-1; DPP-4, dipeptidyl peptidase-4; SGLT2, sodium-dependent glucose cotransporter-2; TAC, tricarboxylic acid cycle; RXR, heterodimers with retinal X receptor;
A liquid chromatography-mass spectrometry assay for quantification of Exendin[9-39] in human plasma
Keywords: DPP-4، dipeptidyl peptidase-4; HI, Hyperinsulinism; GLP-R, Glucagon-like peptide-1 receptor; DPP-4, Dipeptidyl peptidase-4; SPE, Solid-phase extraction; SRM, Selected reaction monitoring; LLOQ, Lower limit of quantification; ULOQ, Upper limit of quantification; SD, Standard DeviationEx
Dipeptidyl peptidase-4 inhibition by Pterocarpus marsupium and Eugenia jambolana ameliorates streptozotocin induced Alzheimer's disease
Keywords: DPP-4، dipeptidyl peptidase-4; T2D, type 2 diabetes; AD, Alzheimer's disease; DPP-4, dipeptidyl peptidase-4; GLP-1, glucagon-like peptide-1; GSK-3, glycogen synthase kinase-3; STZ, streptozotocin; Aβ, amyloid beta; p-tau, phosphorylated tau; RAM, radial arm maze; HB, hole-board; TNF-α,
Serum levels of advanced glycation end products (AGEs) are independently correlated with circulating levels of dipeptidyl peptidase-4 (DPP-4) in humans
Keywords: DPP-4، dipeptidyl peptidase-4; DPP-4, dipeptidyl peptidase-4; GLP-1, glucagon-like peptide-1; GIP, glucose-dependent insulinotropic polypeptides; AGEs, advanced glycation end products; receptor for AGEs, RAGE; BP, blood pressure; hsCRP, high-sensitivity C-reactive protein; ELISA, enzym
A dipeptidyl peptidase-4 inhibitor, sitagliptin, exerts anti-inflammatory effects in type 2 diabetic patients
Keywords: DPP-4، dipeptidyl peptidase-4; DPP-4, dipeptidyl peptidase-4; GLP-1, glucagon-like peptide-1; HOMA-IR, homeostasis model assessment of insulin resistance; BMI, body mass index; LDL-C, low-density lipoprotein cholesterol; CRP, C-reactive protein; IL-6, interleukin-6; IL-10, interleukin-
Saxagliptin: A dipeptidyl peptidase-4 inhibitor ameliorates streptozotocin induced Alzheimer's disease
Keywords: DPP-4، dipeptidyl peptidase-4; Glucagon-like peptide-1; Type 2 diabetes; Amyloid beta; Tau; Inflammatory markers; Hippocampus; Wistar ratsT2D, type 2 diabetes; AD, Alzheimer's disease; DPP-4, dipeptidyl peptidase-4; GLP-1, glucagon-like peptide-1; GSK-3, glycogen synthase kinase-3; STZ
Effects of a single bout of aerobic exercise on short-term low-carbohydrate/high-fat intake-induced postprandial glucose metabolism during an oral glucose tolerance test
Keywords: DPP-4، dipeptidyl peptidase-4; ALT, alanine aminotransferase; iAUC, incremental area under curve; AST, aspartate transaminase; β-HBA, β-hydroxybutyric acid; DPP-4, dipeptidyl peptidase-4; FFA, free fatty acid; GIP, glucose-dependent insulinotropic polypeptide; GLP-1, glucagon-like pept
Serum level of soluble CD26/dipeptidyl peptidase-4 (DPP-4) predicts the response to sitagliptin, a DPP-4 inhibitor, in patients with type 2 diabetes controlled inadequately by metformin and/or sulfonylurea
Keywords: DPP-4، dipeptidyl peptidase-4; ALT, alanine transferase; BMI, body mass index; CV, coefficient of variation; DPP-4, dipeptidyl peptidase-4; eGFR, estimated glomerular filtration rate; GGT, glutamyl transpetidase; GIP, glucose-dependent insulinotropic polypeptide; GLP-1, glucagon-like p
Chronic administration of ezetimibe increases active glucagon-like peptide-1 and improves glycemic control and pancreatic beta cell mass in a rat model of type 2 diabetes
Keywords: DPP-4، dipeptidyl peptidase-4; ABCG5, ATP binding cassette transporters G5; DPP-4, dipeptidyl peptidase-4; FFA, free fatty acids; GLP-1, glucagon-like peptide-1; NASH, non-alcoholic steatohepatitis; NPC1L1, Niemann-Pick C1-like 1; TC, total cholesterol; TG, triglycerideEzetimibe; Gluca
An Albumin-Exendin-4 Conjugate Engages Central and Peripheral Circuits Regulating Murine Energy and Glucose Homeostasis
Keywords: DPP-4، dipeptidyl peptidase-4; DPP-4, dipeptidyl peptidase-4; Ex-4, exendin-4; GLP-1, glucagon-like peptide-1; GLP-1R, GLP-1 receptor; HSA, human serum albumin; T2DM, type 2 diabetes mellitus
Biology of Incretins: GLP-1 and GIP
Keywords: DPP-4، dipeptidyl peptidase-4; DPP-4, dipeptidyl peptidase-4; ER, endoplasmic reticulum; GIP, glucose-dependent insulinotropic polypeptide; GIPR, glucose-dependent insulinotropic polypeptide receptor; GLP-1, glucagon-like peptide-1; GLP-1R, glucagon-like peptide-1 receptor; HbA1c, hemo
Peptide substrate profiling defines fibroblast activation protein as an endopeptidase of strict Gly2-Pro1-cleaving specificity
Keywords: DPP-4، dipeptidyl peptidase-4; FAP, fibroblast activation protein; DPP-4, dipeptidyl peptidase-4; POP, prolyl oligopeptidase; α2AP, α2-antiplasmin; cmk, chloromethyl ketone; AFC, 7-amino-4-trifluoromethyl coumarin; Ac, acetyl; EDANS, 5-[(2-Aminoethyl)amino]naphthalene-1-sulfonic acid;