دانلود مقالات ISI درباره Drp1 + ترجمه فارسی

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Mitochondrial Diseases of the Brain

Keywords: PD; Parkinson's disease; AD; Alzheimer's disease; HD; Huntington's Disease; ALS; Amyotrophic Lateral Sclerosis; TAR DNA; binding protein TDP-43; TCA; tricarboxylic acid cycle; ROS; reactive oxygen species; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydrod

دانلود رایگان متن کامل مقاله ISI 93 صفحه سال انتشار : 2013 سفارش ترجمه

Data of expression status of miR- 29a and its putative target mitochondrial apoptosis regulatory gene DRP1 upon miR-15a and miR-214 inhibition

Keywords: DRP1; miR-15a; Apoptosis; miRNAs inhibition;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2018 سفارش ترجمه

Discovery and characterization of selective small molecule inhibitors of the mammalian mitochondrial division dynamin, DRP1

Keywords: DRP1; Mitochondria; Small molecule inhibitor; Fission; Dynamics;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Intracellular calcium is a rheostat for the STING signaling pathway

Keywords: STING; Mitochondria; Calcium; DRP1; Type I interferon;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

D-chiro-inositol enriched Fagopyrum tataricum (L.) Gaench extract alleviates mitochondrial malfunction and inhibits ER stress/JNK associated inflammation in the endothelium

Keywords: CMC-Na; carboxymethylcellulose sodium; DCI; D-chiro-inositol; DHE; dihydroethidium; Drp1; dynamin-related protein 1; ER; endoplasmic reticulum; FFAs; free fatty acids; HFD; high fat diet; IRE-1α; inositol-requiring enzyme-1α; JNK; Jun n-terminal kinase

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Different mitochondrial fragmentation after irradiation with X-rays and carbon ions in HeLa cells and its influence on cellular apoptosis

Keywords: Mitochondrial dynamics; Different quality radiations; Release of cytochrome c; Apoptosis; Radiosensitivity; LET; linear energy transfer; RBE; relative biological effectiveness; Mfn1; mitofusin1; Mfn2; mitofusin 2; OPA1; optic atrophy 1; Drp1; Dynamin-rela

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Mitochondrial fission is associated with UCP1 activity in human brite/beige adipocytes

Keywords: hMADS; UCP1; DRP1; Brite/beige adipocyte; Mitochondria;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Inhibition of ERK-Drp1 signaling and mitochondria fragmentation alleviates IGF-IIR-induced mitochondria dysfunction during heart failure

Keywords: AAV; adenovirus-associated virus; ANP; atrial natriuretic protein; ANG II; angiotensin II; BNP; brain natriuretic protein; Drp1; dynamin-related protein 1; ERK; extracellular signal-regulated kinase; IGF-II; insulin-like growth factor II; IGF-IIR; insulin

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Mechanisms of mitochondrial toxicity of the kinase inhibitors ponatinib, regorafenib and sorafenib in human hepatic HepG2 cells

Keywords: MKI; multikinase inhibitor; ALT; alanine aminotransferase; AST; aspartate aminotransferase; DRP1; dynamin-related protein 1; FIS1; mitochondrial fission 1; ROS; reactive oxygen species; DMSO; dimethylsulfoxide; AK; adenylate kinase; PBS; phosphate buffere

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Renal ischemia/reperfusion-induced mitophagy protects against renal dysfunction via Drp1-dependent-pathway

Keywords: Acute kidney injury; Ischemia reperfusion; Mitophagy; Drp1;

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2018 سفارش ترجمه

TDP-43 interacts with mitochondrial proteins critical for mitophagy and mitochondrial dynamics

Keywords: APP; amyloid precursor protein; VDAC1; voltage dependent anion channel 1; TDP-43; TAR DNA binding protein of 43 kDa; PSEN1/PS1; presenilin 1; AD; Alzheimer disease; hnRNP; heterogeneous nuclear ribonucleoprotein; ALS; amyotrophic lateral sclerosis; MND;

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2018 سفارش ترجمه

Protective effect of mitochondrial-targeted antioxidant MitoQ against iron ion 56Fe radiation induced brain injury in mice

Keywords: IR; iron ion 56Fe radiation; ROS; reactive oxygen species; cyto c; cytochrome c; Mfn2; mitofusin2; Drp1; dynamic-like protein; OPA1; andoptic atrophy gene1; ATP; adenosine triphosphate; mtDNA; mitochondrial DNA; nDNA; nuclear DNA; ADP; adenosine 5′-diph

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2018 سفارش ترجمه

RhoA regulates Drp1 mediated mitochondrial fission through ROCK to protect cardiomyocytes

Keywords: RhoA; Sphingosine-1-phosphate; Drp1; Mitochondria; Fission; Cardioprotection;

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2018 سفارش ترجمه

PGAM5 regulates PINK1/Parkin-mediated mitophagy via DRP1 in CCCP-induced mitochondrial dysfunction

Keywords: CCCP; PGAM5; DRP1; PINK1; Mitophagy; Mitochondrial dynamics;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

Relationship between OPA1 and cardiolipin in mitochondrial inner-membrane fusion

Keywords: OPA1; optic atrophy 1; IM; inner membrane; OM; outer membrane; CL; cardiolipin; KO; knockout; Mfns; mitofusins; MEF; mouse embryonic fibroblast; mtDNA; mitochondrial DNA; Drp1; dynamin-related protein 1; Mff; mitochondrial fission factor; MiD49/MIEF2; mit

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

Isoliquiritigenin attenuates glutamate-induced mitochondrial fission via calcineurin-mediated Drp1 dephosphorylation in HT22 hippocampal neuron cells

Keywords: Glutamate; Isoliquiritigenin; Neurotoxicity; Mitochondrial dynamics; Drp1; Calcineurin;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

Melatonin inhibits rotenone-induced SH-SY5Y cell death via the downregulation of Dynamin-Related Protein 1 expression

Keywords: Melatonin; Rotenone; SH-SY5Y cell; Drp1; Cell death; Mitochondrial dysfunction;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

Loss of DJ-1 promotes browning of white adipose tissue in diet-induced obese mice

Keywords: ACC; acyl-CoA carboxylase; Actb; beta-actin encoding gene; AMPK; AMP-activated protein kinase; ATG; autophagy-related protein; ATGL; adipose triglyceride lipase; ATP5B; ATP synthase subunit beta; β3-AR; beta 3 adrenergic receptor; C/EBPα; CCAAT/enhancer

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Heme oxygenase-1 protects liver against ischemia/reperfusion injury via phosphoglycerate mutase family member 5-mediated mitochondrial quality control

Keywords: ALT; Alanine aminotransferase; Drp1; dynamin-related protein 1; EDTA; ethylenediaminetetraacetic acid; GDH; glutamate dehydrogenase; H&E; hematoxylin&eosin; HO-1; heme oxygenase-1; H/R; hypoxia/reoxygenation; IL; interleukin; I/R; ischemia/reperfusion; LP

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Mitochondria as pharmacological targets in Down syndrome

Keywords: AD; Alzheimer's disease; AGO; Argonaute proteins; AMPK; AMP-activated protein kinase; ANTs; adenine nucleotide translocators; AK; adenylate kinase; APP; amyloid-β precursor protein; ASD; autism spectrum disorder; CAT; catalase; CNS; central nervous syste

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2018 سفارش ترجمه

ALS-associated mutation SOD1G93A leads to abnormal mitochondrial dynamics in osteocytes

Keywords: ALS; Amyotrophic lateral sclerosis; Drp1; dynamin-related protein 1; G93A; an ALS mouse model with overexpression of ALS-associated mutation SOD1G93A; GFP; green fluorescence protein; OPA1; optic atrophy protein 1; SOD1; superoxide dismutase 1; SOD1G93A;

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2018 سفارش ترجمه

Modulating autophagy in cancer therapy: Advancements and challenges for cancer cell death sensitization

Keywords: 3-MA; 3-Methyl Adenine; Akt; Protein kinase B; AMP; Adenosine monophosphate; AMPK; AMP-activated protein kinase; Atg; Autophagy related genes; ATP; Adenosine triphosphate; Bak; Bcl-2 homologous antagonist/killer; Bax; Bcl-2-associated X protein; BCL-2; B-

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2018 سفارش ترجمه

Effect of a long-term treatment with metformin in dystrophic mdx mice: A reconsideration of its potential clinical interest in Duchenne muscular dystrophy

Keywords: DMD; Duchenne muscular dystrophy; DGC; dystrophin-associated glycoprotein complex; ECM; extracellular matrix; SIRT1; Sirtuin1; PGC-1α; peroxisome proliferator-activated receptor γ coactivator 1α; PPARγ; peroxisome proliferator-activated receptor γ; B

دانلود رایگان متن کامل مقاله ISI 60 صفحه سال انتشار : 2018 سفارش ترجمه

FOXO1 inhibition potentiates endothelial angiogenic functions in diabetes via suppression of ROCK1/Drp1-mediated mitochondrial fission

Keywords: AGEs; advanced glycation end products; Drp1; dynamin-relatedprotein-1; ECs; endothelial cells; FOXO1; forkhead box O1; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; HUVECs; human umbilical vein endothelial cells; HG; high glucose concentration; mtROS;

دانلود رایگان متن کامل مقاله ISI 63 صفحه سال انتشار : 2018 سفارش ترجمه

Inhibition of Drp1 attenuates mitochondrial damage and myocardial injury in Coxsackievirus B3 induced myocarditis

Keywords: Viral myocarditis; Drp1; Mdivi1; Mitochondrial damage;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Anti-inflammatory effect of oleuropein on microglia through regulation of Drp1-dependent mitochondrial fission

Keywords: NADPH oxidase; nicotinamide adenine dinucleotide phosphate oxidase; Oleuropein; Microglia; Inflammation; Mitochondrial dynamics; Drp1; ROS;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Developmentally regulated GTP-binding protein 2 depletion leads to mitochondrial dysfunction through downregulation of dynamin-related protein 1

Keywords: DRG2; Mitochondrial dysfunction; Drp1; Mitochondrial swelling;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Tyrphostin A9 improves blastocyst development in porcine embryos through induction of dynamin-related protein 1-dependent mitochondrial fission

Keywords: TA9; tyrphostin A9; Drp1; dynamics-related protein 1; MMP; mitochondrial membrane potential; COCs; cumulus-oocyte complexes; PMSG; pregnant mare's serum gonadotropin; hCG; human chorionic gonadotropin; IVM; in vitro maturation; IVF; in vitro fertilization

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Drp1 mediates compression-induced programmed necrosis of rat nucleus pulposus cells by promoting mitochondrial translocation of p53 and nuclear translocation of AIF

Keywords: Intervertebral disc degeneration; Nucleus pulposus cells; Compression; Programmed necrosis; Dynamin-related protein 1 (Drp1); p53; Apoptosis-inducing factor (AIF); LBP; low back pain; IDD; intervertebral disc degeneration; NP; nucleus pulposus; Drp1; dyna

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Sulforaphane is a Nrf2-independent inhibitor of mitochondrial fission

Keywords: Sulforaphane; Nrf2; Drp1; Mitochondria; Fission; Fusion; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Redox regulation of electrophilic signaling by reactive persulfides in cardiac cells

Keywords: CBS; cystathionine β-synthase; CSE; cystathionine γ-lyase; Drp1; dynamin-related protein 1; 15d-PGJ2; 15-deoxy-Δ12,14-prostaglandin J2; ERK; extracellular signal-regulated kinase; G protein; GTP-binding protein; GC; guanylate cyclase; GDP; guanosine 5'

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Research PaperRIP1-RIP3-DRP1 pathway regulates NLRP3 inflammasome activation following subarachnoid hemorrhage

Keywords: RIP1; RIP3; DRP1; NLRP3; Early brain injury; Subarachnoid hemorrhage;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Drp1 regulates mitochondrial morphology and cell proliferation in cutaneous squamous cell carcinoma

Keywords: Drp1; dynamin-related protein 1; SCC; squamous cell carcinoma; EGFR; epidermal growth factor receptor; HPEKp; human primary epidermal keratinocyte progenitor; NHDF; normal human dermal fibroblasts; FACS; fluorescence-activated cell sorting; MAPK; mitogen-

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Inhibition of Drp1 protects against senecionine-induced mitochondria-mediated apoptosis in primary hepatocytes and in mice

Keywords: ALT; Alanine aminotransferase; ActD; Actinomycin D; CYP; Cytochrome P450; CQ; Chloroquine; Drp1; Dynamin-related protein 1; DHPAs; Dehydropyrrolizidine alkaloids; DHR; dehydroretronecine; EM; Electron microscopy; GSH; Glutathione; GAPDH; Glyceradehyde-3-p

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

TRPC6-mediated ERK1/2 phosphorylation prevents dentate granule cell degeneration via inhibiting mitochondrial elongation

Keywords: DRP1; Epilepsy; Mitochondria; Protein kinase; Protein phosphatase; Seizure; U0126; Atropine methylbromide (PubChem CIH: 656597); Isoflurane (PubChem CIH: 3763); LiCl (PubChem CIH: 433294); Pilocarpine hydrochloride (PubChem CIH: 5909); U0126 (PubChem CIH:

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Modulating mitochondrial morphology enhances antitumor effect of 5-ALA-mediated photodynamic therapy both in vitro and in vivo

Keywords: PDT; photodynamic therapy; 5-ALA; 5-aminolevulinic acid; ROS; reactive oxygen species; TMRM; tetramethylrhodamine methyl esters; PpIX; protoporphyrin IX; Drp1; dynamin-related protein 1; Mff; mitochondrial fusion protein; mPTP; mitochondrial permeability

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

LCZ696 improves cardiac function via alleviating Drp1-mediated mitochondrial dysfunction in mice with doxorubicin-induced dilated cardiomyopathy

Keywords: LCZ696; Doxorubicin; Mitochondrial dynamics; Drp1; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Dengue virus induces mitochondrial elongation through impairment of Drp1-triggered mitochondrial fission

Keywords: Dengue virus; Drp1; Mitochondria; Fusion; Fission; Live-cell imaging; Dendritic cells;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Expanding perspectives on the significance of mitophagy in cancer

Keywords: ALS; amyotrophic lateral sclerosis; AR; androgen receptor; ASC; apoptosis-associated speck-like protein containing a CARD; ATM; ataxia telangiectasia mutated; BCL-2; breakpoint cluster locus-2; BCL-XL; BCL2-like 1 long; BNIP3; BCL2 interacting protein 3;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

CDK5 inhibitors prevent astroglial apoptosis and reactive astrogliosis by regulating PKA and DRP1 phosphorylations in the rat hippocampus

Keywords: SE; status epilepticus; MFN1; mitofusin 1; MFN2; mitofusin 2; OPA1; optic atrophy 1; DRP1; dynamin-related protein 1; Fis-1; fission related protein-1; MFF; mitochondrial fission factor; CDK5; cyclin-dependent kinase 5; PKA; protein kinase A; AIF; apoptot

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Research PaperInhibition of Drp1 hyper-activation is protective in animal models of experimental multiple sclerosis

Keywords: Drp1; Oligodendrocytes; Necroptosis; Multiple sclerosis;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Role of PARL-PINK1-Parkin pathway in adipocyte differentiation

Keywords: Adipogenesis; Parkin; Peroxisome proliferator-activated receptor-γ (PPARγ); Presenilin associated rhomboid-like protein (PARL); PTEN-induced kinase 1 (PINK1); C/EBPα/β; CCAAT-enhancer-binding protein-α/− β; DRP1; dynamin-related protein-1; FABP4;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2017 سفارش ترجمه

Mitophagy and age-related pathologies: Development of new therapeutics by targeting mitochondrial turnover

Keywords: AMPK; AMP-activated protein kinase; ATP; adenosine triphosphate; BNIP3; Bcl2/adenovirus E1B 19 kDa-interacting protein 3; BNIP3-like; (BNIP3L)/NIX; DRP1; dynamin related protein 1; ETC; electron transport chain; FUNDC1; FUN14 domain-containing 1; GABARAP

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2017 سفارش ترجمه

Metabolic reprogramming in cancer cells, consequences on pH and tumour progression: Integrated therapeutic perspectives with dietary lipids as adjuvant to anticancer treatment

Keywords: α-SMA; α-smooth muscle actin; AMPK; AMP-activated protein kinase; bHLH; basic Helix-Loop-Helix; DHA; docosahexaenoic acid (22:6n-3); Drp1; dynamin-related protein 1; ECM; extracellular matrix; EMT; epithelial-to-mesenchymal transition; EPA; eicosapentae

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2017 سفارش ترجمه

Connecting mitochondrial dynamics and life-or-death events via Bcl-2 family proteins

Keywords: Mitochondria; Apoptosis; Mitochondrial dynamics; Neurons; Bcl-xL; Drp1;

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2017 سفارش ترجمه

Stress-induced hyperacetylation of microtubule enhances mitochondrial fission and modulates the phosphorylation of Drp1 at 616Ser

Keywords: Mitochondria; Microtubule; Acetylation; αTAT-1; Drp1; Fission;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2017 سفارش ترجمه

Exercise increases mitochondrial complex I activity and DRP1 expression in the brains of aged mice

Keywords: PGC-1α; peroxisome proliferator-activated receptor gamma co-activator 1α; TFAM; mitochondrial transcription factor A; BDNF; brain-derived neurotrophic factor; ETC; electron transport chain; OC; old control group; OT; old trained group; YC; young control

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2017 سفارش ترجمه

Advanced glycation end products receptor RAGE controls myocardial dysfunction and oxidative stress in high-fat fed mice by sustaining mitochondrial dynamics and autophagy-lysosome pathway

Keywords: ADP; adenosine diphosphate; AFC; amino-4-trifluoromethyl coumarin; Akt; protein kinase B; ATP; adenosine triphosphate; Drp1; dynamin-related protein 1; ERK; extracellular signal regulated kinases; Fis1; mitochondrial fission-1 protein; Gp91phox; glycoprot

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2017 سفارش ترجمه

Inhibition of Drp1-mediated mitochondrial fission improves mitochondrial dynamics and bioenergetics stimulating neurogenesis in hippocampal progenitor cells from a Down syndrome mouse model

Keywords: AR; aspect ratio; BrdU; bromodeoxyuridine; CaN; calcineurin; DAPI; 4',6-diamidino-2-phenylindole; DCX; doublecortin; Drp1; dynamin-related protein 1; DS; Down syndrome; L-Opa; long Opa1; Mdivi-1; mitochondrial division inhibitor 1; Mnf2; mitofusin 2; NPCs

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2017 سفارش ترجمه

Deficiencies in mitochondrial dynamics sensitize Caenorhabditis elegans to arsenite and other mitochondrial toxicants by reducing mitochondrial adaptability

Keywords: OMM; outer mitochondrial membrane; DRP1; dynamin-related protein-1; MFN1; mitofusin 1; MFN2; mitofusin 2; mtDNA; mitochondrial DNA; PINK1; PTEN-induced putative kinase 1; PARK2; parkin; DOA; dominant optic atrophy; CMT2A; Charcot-Marie-Tooth neuropathy ty

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2017 سفارش ترجمه